Assembly of active LPL and LIPC lipase complexes
|
|
|
- ANGPT5
- ANGPTL3
- ANGPTL4
- ANGPTL8
- APC2
- APOA4
- APOA5
- APOC2
- ARP4
- C16orf26
- C19orf80
- CREB3L3
- CREBH
- FGF21
- FUR
- FURIN
- GPIHBP1
- HBP1
- HFARP
- HTGL
- KIAA0091
- LIPC
- LIPD
- LMF1
- LMF2
- LPL
- MBTPS1
- MBTPS2
- PACE
- PACE4
- PC5
- PC6
- PCSK3
- PCSK5
- PCSK6
- PGAR
- RAP3
- RIFL
- S1P
- S2P
- SKI1
- TMEM112
- TMEM112B
- TMEM153
|
|
CREB3 factors activate genes
|
|
|
- AIBZIP
- BBF2H7
- C5orf41
- CREB3
- CREB3L1
- CREB3L2
- CREB3L3
- CREB3L4
- CREB4
- CREBH
- CREBRF
- DCSTAMP
- JAL
- KIAA0091
- LZIP
- MBTPS1
- MBTPS2
- OASIS
- S1P
- S2P
- SKI1
- TM7SF4
|
|
Voltage gated Potassium channels
|
|
|
- C1orf30
- EAG
- EAG1
- EAG2
- ERG
- ERG1
- ERG2
- ERG3
- HERG
- HGK5
- KCNA1
- KCNA10
- KCNA1B
- KCNA2
- KCNA2B
- KCNA3
- KCNA3B
- KCNA4
- KCNA4L
- KCNA5
- KCNA6
- KCNA7
- KCNA8
- KCNA9
- KCNAB1
- KCNAB2
- KCNAB3
- KCNB1
- KCNB2
- KCNC1
- KCNC2
- KCNC3
- KCNC4
- KCND1
- KCND2
- KCND3
- KCNF1
- KCNF2
- KCNG1
- KCNG2
- KCNG3
- KCNG4
- KCNH1
- KCNH2
- KCNH3
- KCNH4
- KCNH5
- KCNH6
- KCNH7
- KCNH8
- KCNK2
- KCNQ1
- KCNQ2
- KCNQ3
- KCNQ4
- KCNQ5
- KCNS1
- KCNS2
- KCNS3
- KCNV1
- KCNV2
- KIAA1044
- KIAA1144
- KIAA1282
- KVLQT1
|
|
Specification of primordial germ cells
|
|
|
- BLIMP1
- BMP2B
- BMP4
- CBFA2T2
- CXCR4
- DVR4
- EHT
- EOMES
- GP36
- KIAA1546
- MTGR1
- NANOG
- NANOS3
- NOS3
- OCT3
- OCT4
- OTF3
- PDPN
- POU5F1
- PRDM1
- SOX17
- TBR2
- TET2
- TFAP2C
|
|
RHOBTB2 GTPase cycle
|
|
|
- 99D8.1
- ACTG
- ACTG1
- ACTN1
- BAT1
- CCT2
- CCT6
- CCT6A
- CCT7
- CCTB
- CCTH
- CCTZ
- CDC37
- CDC37A
- CUL3
- D0S117E
- DBC2
- DBN1
- DCAF14
- DDX39B
- HNRNPC
- HNRPC
- HNRPG
- HSP90A
- HSP90AA1
- HSP90AB1
- HSP90B
- HSPC1
- HSPC2
- HSPC3
- HSPCA
- HSPCB
- KIAA0389
- KIAA0617
- KIAA0717
- MSI2
- MYO6
- NDR1
- NIP7-1
- PHIP
- PTK9
- RBMX
- RBMXP1
- RHOBTB2
- SFRS10
- SRM160
- SRRM1
- STK38
- TMOD3
- TRA2B
- TRP32
- TWF1
- TXL
- TXNL
- TXNL1
- UAP56
- WDR11
|
|
RHOBTB1 GTPase cycle
|
|
|
- 99D8.1
- BRE1A
- CCT2
- CCT7
- CCTB
- CCTH
- COPS1
- COPS2
- COPS4
- CPSF7
- CSN1
- CSN2
- CSN4
- CUL3
- D0S117E
- DBN1
- GPS1
- HNRNPC
- HNRPC
- HNRPG
- KIAA0389
- KIAA0617
- KIAA0619
- KIAA0740
- KIAA0929
- MINT
- MYO6
- NDR1
- NIP7-1
- P2PR
- PACT
- PDE5
- PDE5A
- RBBP6
- RBMX
- RBMXP1
- RBQ1
- RHOBTB1
- RNF20
- ROCK1
- ROCK2
- SFRS10
- SHARP
- SPEN
- SRM160
- SRRM1
- STK38
- TRA2B
- TRIP15
- TRP32
- TXL
- TXNL
- TXNL1
- VIM
|
|
Ovarian tumor domain proteases
|
|
|
- ABIN2
- ABIN3
- APC
- ARH12
- ARHA
- C14orf137
- C15orf16
- CAP-1
- CARD15
- CARD4
- CARDIAK
- CDC2
- CDC28A
- CDK1
- CDKN1
- CEZANNE2
- CRAF1
- DDX58
- DP2.5
- DUBA8
- EFP
- ESR
- ESR1
- FIP3
- FLIP1
- HEL-220
- HEL-S-70
- HIN7
- IFIH1
- IKBKG
- IPS1
- KIAA0113
- KIAA0459
- KIAA1271
- KIAA1850
- LIND
- MAVS
- MDA5
- MMAC1
- NAF1
- NEMO
- NOD1
- NOD2
- NR3A1
- OTB1
- OTB2
- OTU1
- OTU2
- OTUB1
- OTUB2
- OTUD2
- OTUD3
- OTUD5
- OTUD7
- OTUD7A
- OTUD7B
- OTUD7C
- P34CDC2
- P53
- PTEN
- RH116
- RHO12
- RHOA
- RICK
- RIGI
- RIP
- RIP1
- RIP2
- RIPK1
- RIPK2
- RNF128
- RNF135
- RNF147
- RNF85
- RNF87
- RPS27A
- SFT
- TEP1
- TNFAIP3
- TNIP1
- TNIP2
- TNIP3
- TP53
- TRABID
- TRAF3
- TRAF6
- TRAFAMN
- TRIM25
- TRIM4
- UBA52
- UBA80
- UBB
- UBC
- UBC5A
- UBCEP1
- UBCEP2
- UBCH5
- UBCH5A
- UBE2D1
- VCIP135
- VCP
- VCPIP1
- VISA
- YOD1
- ZA20D1
- ZNF147
- ZRANB1
|
|
Selenoamino acid metabolism
|
|
|
- AIMP1
- AIMP2
- AIMP3
- DARS
- DARS1
- EEF1E1
- EMAP2
- EPRS
- EPRS1
- GLNS
- IARS
- IARS1
- JTV1
- KARS
- KARS1
- KIAA0070
- KIAA1352
- LARS
- LARS1
- MARS
- MARS1
- P18
- PARS
- QARS
- QARS1
- QPRS
- RARS
- RARS1
- SCYE1
|
|
Cytosolic tRNA aminoacylation
|
- Alanine--tRNA ligase, cytoplasmic
- Aminoacyl tRNA synthase complex-interacting multifunctional protein 1
- Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
- Arginine--tRNA ligase, cytoplasmic
- Asparagine--tRNA ligase, cytoplasmic
- Aspartate--tRNA ligase, cytoplasmic
- Bifunctional glutamate/proline--tRNA ligase
- Cysteine--tRNA ligase, cytoplasmic
- Eukaryotic translation elongation factor 1 epsilon-1
- Glutamine--tRNA ligase
- Glycine--tRNA ligase
- Histidine--tRNA ligase, cytoplasmic
- Inorganic pyrophosphatase
- Isoleucine--tRNA ligase, cytoplasmic
- Leucine--tRNA ligase, cytoplasmic
- Lysine--tRNA ligase
- Methionine--tRNA ligase, cytoplasmic
- Phenylalanine--tRNA ligase alpha subunit
- Phenylalanine--tRNA ligase beta subunit
- Serine--tRNA ligase, cytoplasmic
- Threonine--tRNA ligase 1, cytoplasmic
- Tryptophan--tRNA ligase, cytoplasmic
- Tyrosine--tRNA ligase, cytoplasmic
- Valine--tRNA ligase
|
|
- AARS
- AARS1
- AIMP1
- AIMP2
- AIMP3
- CARS
- CARS1
- DARS
- DARS1
- EEF1E1
- EMAP2
- EPRS
- EPRS1
- FARS
- FARSA
- FARSB
- FARSL
- FARSLA
- FARSLB
- FRSB
- G7A
- GARS
- GARS1
- GLNS
- HARS
- HARS1
- HRS
- IARS
- IARS1
- IFI53
- IOPPP
- JTV1
- KARS
- KARS1
- KIAA0070
- KIAA1352
- LARS
- LARS1
- MARS
- MARS1
- NARS
- NARS1
- NRS
- P18
- PARS
- PP
- PPA1
- QARS
- QARS1
- QPRS
- RARS
- RARS1
- SARS
- SARS1
- SCYE1
- SERS
- TARS
- TARS1
- VARS
- VARS1
- VARS2
- WARS
- WARS1
- WRS
- YARS
- YARS1
|
|
HHAT G278V doesn't palmitoylate Hh-Np
|
|
|
- DHH
- HHAT
- IHH
- MART2
- SHH
- SKI1
|
|
Ligand-receptor interactions
|
|
|
- BOC
- CDO
- CDON
- DHH
- GAS1
- HHIP
- HIP
- IHH
- PTCH
- PTCH1
- SHH
|
|
Transcriptional regulation of testis differentiation
|
|
|
- AD4BP
- AMH
- DHH
- DMRT1
- DMT1
- FGF9
- FOG2
- FTZF1
- GATA4
- MIF
- NR5A1
- PDS
- PTGDS
- SF1
- SOX9
- SRY
- TDF
- WT1
- ZFPM2
- ZNF89B
|
|
FGFR3c ligand binding and activation
|
|
|
- FGF1
- FGF16
- FGF18
- FGF2
- FGF20
- FGF23
- FGF4
- FGF9
- FGFA
- FGFB
- GALNT3
- HST
- HSTF1
- HYPF
- KS3
|
|
PI-3K cascade:FGFR3
|
|
|
- FGF1
- FGF16
- FGF18
- FGF2
- FGF20
- FGF23
- FGF4
- FGF9
- FGFA
- FGFB
- FRS2
- GAB1
- GRB1
- HST
- HSTF1
- HYPF
- KS3
- PIK3CA
- PIK3R1
- PTP2C
- PTPN11
- SHPTP2
|
|
Signaling by activated point mutants of FGFR3
|
|
|
- FGF1
- FGF16
- FGF18
- FGF2
- FGF20
- FGF23
- FGF4
- FGF9
- FGFA
- FGFB
- FGFR3
- HST
- HSTF1
- HYPF
- JTK4
- KS3
|
|
Phospholipase C-mediated cascade; FGFR3
|
|
|
- FGF1
- FGF16
- FGF18
- FGF2
- FGF20
- FGF23
- FGF4
- FGF9
- FGFA
- FGFB
- HST
- HSTF1
- HYPF
- KS3
- PLC1
- PLCG1
|
|
FGFR2c ligand binding and activation
|
|
|
- FGF1
- FGF16
- FGF18
- FGF2
- FGF20
- FGF23
- FGF4
- FGF6
- FGF9
- FGFA
- FGFB
- HST
- HST2
- HSTF1
- HSTF2
- HYPF
- KS3
|
|
Negative regulation of FGFR3 signaling
|
|
|
- CBL
- CBL2
- ERK1
- ERK2
- FGF1
- FGF16
- FGF18
- FGF2
- FGF20
- FGF23
- FGF4
- FGF9
- FGFA
- FGFB
- FRS2
- HST
- HSTF1
- HYPF
- KS3
- MAPK1
- MAPK3
- PRKM1
- PRKM2
- PRKM3
- PTP2C
- PTPN11
- RNF55
- RPS27A
- SHPTP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
|
|
SHC-mediated cascade:FGFR3
|
|
|
- FGF1
- FGF16
- FGF18
- FGF2
- FGF20
- FGF23
- FGF4
- FGF9
- FGFA
- FGFB
- HRAS
- HRAS1
- HST
- HSTF1
- HYPF
- KS3
- NRAS
- SOS1
|
|
Signaling by FGFR3 in disease
|
|
|
- FGF1
- FGF16
- FGF18
- FGF2
- FGF20
- FGF23
- FGF4
- FGF9
- FGFA
- FGFB
- FGFR3
- FRS2
- GAB1
- GRB1
- HRAS
- HRAS1
- HST
- HSTF1
- HYPF
- JTK4
- KS3
- NRAS
- PIK3CA
- PIK3R1
- PLC1
- PLCG1
- SOS1
|
|
FGFR4 ligand binding and activation
|
|
|
- FGF1
- FGF16
- FGF18
- FGF19
- FGF2
- FGF20
- FGF23
- FGF4
- FGF6
- FGF9
- FGFA
- FGFB
- FGFR4
- HST
- HST2
- HSTF1
- HSTF2
- HYPF
- JTK2
- KS3
- TKF
|
|
PI-3K cascade:FGFR4
|
|
|
- FGF1
- FGF16
- FGF18
- FGF19
- FGF2
- FGF20
- FGF23
- FGF4
- FGF6
- FGF9
- FGFA
- FGFB
- FGFR4
- FRS2
- GAB1
- GRB1
- HST
- HST2
- HSTF1
- HSTF2
- HYPF
- JTK2
- KLB
- KS3
- PIK3CA
- PIK3R1
- PTP2C
- PTPN11
- SHPTP2
- TKF
|
|
Phospholipase C-mediated cascade; FGFR4
|
|
|
- FGF1
- FGF16
- FGF18
- FGF19
- FGF2
- FGF20
- FGF23
- FGF4
- FGF6
- FGF9
- FGFA
- FGFB
- FGFR4
- HST
- HST2
- HSTF1
- HSTF2
- HYPF
- JTK2
- KLB
- KS3
- PLC1
- PLCG1
- TKF
|
|
Negative regulation of FGFR4 signaling
|
|
|
- CBL
- CBL2
- ERK1
- ERK2
- FGF1
- FGF16
- FGF18
- FGF19
- FGF2
- FGF20
- FGF23
- FGF4
- FGF6
- FGF9
- FGFA
- FGFB
- FGFR4
- FRS2
- HST
- HST2
- HSTF1
- HSTF2
- HYPF
- JTK2
- KLB
- KS3
- MAPK1
- MAPK3
- PRKM1
- PRKM2
- PRKM3
- PTP2C
- PTPN11
- RNF55
- RPS27A
- SHPTP2
- TKF
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
|
|
SHC-mediated cascade:FGFR4
|
|
|
- FGF1
- FGF16
- FGF18
- FGF19
- FGF2
- FGF20
- FGF23
- FGF4
- FGF6
- FGF9
- FGFA
- FGFB
- FGFR4
- HRAS
- HRAS1
- HST
- HST2
- HSTF1
- HSTF2
- HYPF
- JTK2
- KLB
- KS3
- NRAS
- SOS1
- TKF
|
|