GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **1351 - 1375** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol
TGFBR1 LBD Mutants in Cancer	Peptidyl-prolyl cis-trans isomerase FKBP1A TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein	P01137 P36897 P37173 P62942	ALK5 FKBP1 FKBP12 FKBP1A SKR4 TGFB TGFB1 TGFBR1 TGFBR2
SMAD2/3 Phosphorylation Motif Mutants in Cancer	Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein	P01137 P36897 P37173 P84022 Q15796	ALK5 MADH2 MADH3 MADR2 SKR4 SMAD2 SMAD3 TGFB TGFB1 TGFBR1 TGFBR2
TGFBR1 KD Mutants in Cancer	Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein	P01137 P36897 P37173 P84022 Q15796	ALK5 MADH2 MADH3 MADR2 SKR4 SMAD2 SMAD3 TGFB TGFB1 TGFBR1 TGFBR2
TGFBR2 Kinase Domain Mutants in Cancer	TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein	P01137 P36897 P37173	ALK5 SKR4 TGFB TGFB1 TGFBR1 TGFBR2
TGFBR2 MSI Frameshift Mutants in Cancer	TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein	P01137 P37173	TGFB TGFB1 TGFBR2
ARMS-mediated activation	14-3-3 protein beta/alpha Adapter molecule crk Beta-nerve growth factor High affinity nerve growth factor receptor Kinase D-interacting substrate of 220 kDa Ras-related protein Rap-1A Serine/threonine-protein kinase B-raf	P01138 P04629 P15056 P31946 P46108 P62834 Q9ULH0	ARMS BRAF BRAF1 CRK KIAA1250 KIDINS220 KREV1 MTC NGF NGFB NTRK1 RAFB1 RAP1A TRK TRKA YWHAB
Signalling to p38 via RIT and RIN	Beta-nerve growth factor GTP-binding protein Rit1 GTP-binding protein Rit2 High affinity nerve growth factor receptor Serine/threonine-protein kinase B-raf	P01138 P04629 P15056 Q92963 Q99578	BRAF BRAF1 MTC NGF NGFB NTRK1 RAFB1 RIBB RIN RIT RIT1 RIT2 ROC1 ROC2 TRK TRKA
PLC-gamma1 signalling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Beta-nerve growth factor High affinity nerve growth factor receptor	P01138 P04629 P19174	MTC NGF NGFB NTRK1 PLC1 PLCG1 TRK TRKA
Signalling to STAT3	Beta-nerve growth factor High affinity nerve growth factor receptor Signal transducer and activator of transcription 3	P01138 P04629 P40763	APRF MTC NGF NGFB NTRK1 STAT3 TRK TRKA
TRKA activation by NGF	Beta-nerve growth factor High affinity nerve growth factor receptor	P01138 P04629	MTC NGF NGFB NTRK1 TRK TRKA
NRIF signals cell death from the nucleus	Beta-nerve growth factor Centromere protein R Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Mitogen-activated protein kinase 8 Nicastrin Polyubiquitin-B Polyubiquitin-C Presenilin-1 Presenilin-2 Sequestosome-1 TNF receptor-associated factor 6 Tumor necrosis factor receptor superfamily member 16 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P01138 P08138 P0CG47 P0CG48 P45983 P49768 P49810 P62979 P62987 Q13352 Q13501 Q8WW43 Q92542 Q96BI3 Q9NZ42 Q9Y4K3	AD3 AD4 APH1A APH1B CENPR ITGB3BP JNK1 KIAA0253 MAPK8 NCSTN NGF NGFB NGFR NRIF3 ORCA OSIL PEN2 PRKM8 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RNF85 RPS27A SAPK1 SAPK1C SQSTM1 STM2 TNFRSF16 TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
NADE modulates death signalling	14-3-3 protein epsilon Beta-nerve growth factor Caspase-2 Caspase-3 Protein BEX3 Tumor necrosis factor receptor superfamily member 16	P01138 P08138 P42574 P42575 P62258 Q00994	BEX3 CASP2 CASP3 CPP32 DXS6984E ICH1 NADE NEDD2 NGF NGFB NGFR NGFRAP1 TNFRSF16 YWHAE
Axonal growth stimulation	Beta-nerve growth factor Rho GDP-dissociation inhibitor 1 Transforming protein RhoA Tumor necrosis factor receptor superfamily member 16	P01138 P08138 P52565 P61586	ARH12 ARHA ARHGDIA GDIA1 NGF NGFB NGFR RHO12 RHOA TNFRSF16
NFG and proNGF binds to p75NTR	Beta-nerve growth factor Sortilin-related VPS10 domain containing receptor 3 Tumor necrosis factor receptor superfamily member 16	P01138 P08138 Q17R88	NGF NGFB NGFR SORCS3 TNFRSF16
NGF processing	Beta-nerve growth factor Furin Proprotein convertase subtilisin/kexin type 5 Proprotein convertase subtilisin/kexin type 6	P01138 P09958 P29122 Q92824	FUR FURIN NGF NGFB PACE PACE4 PC5 PC6 PCSK3 PCSK5 PCSK6
Frs2-mediated activation	14-3-3 protein beta/alpha Beta-nerve growth factor Crk-like protein Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibroblast growth factor receptor substrate 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Rap guanine nucleotide exchange factor 1 Ras-related protein Rap-1A Serine/threonine-protein kinase B-raf	P01138 P15056 P27361 P28482 P31946 P36507 P46109 P62834 Q02750 Q13905 Q8WU20	BRAF BRAF1 CRKL ERK1 ERK2 FRS2 GRF2 KREV1 MAP2K1 MAP2K2 MAPK1 MAPK3 MEK1 MEK2 MKK2 NGF NGFB PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 RAFB1 RAP1A RAPGEF1 YWHAB
Physiological factors	Atrial natriuretic peptide receptor 1 Atrial natriuretic peptide receptor 2 Atrial natriuretic peptide-converting enzyme C-type natriuretic peptide Histone acetyltransferase KAT2B Homeobox protein Nkx-2.5 Homeodomain-interacting protein kinase 1 Homeodomain-interacting protein kinase 2 Liver carboxylesterase 1 Natriuretic peptides A Neprilysin T-box transcription factor TBX5 Transcription factor GATA-4 WW domain-containing transcription regulator protein 1	P01160 P08473 P16066 P20594 P23141 P23582 P43694 P52952 Q86Z02 Q92831 Q99593 Q9GZV5 Q9H2X6 Q9Y5Q5	ANP ANPRA ANPRB CES1 CES2 CNP2 CORIN CRN CSX EPN GATA4 HIPK1 HIPK2 KAT2B KIAA0630 MME MYAK NBAK2 NKX2-5 NKX2.5 NKX2E NPPA NPPC NPR1 NPR2 PCAF PND SES1 TAZ TBX5 TMPRSS10 WWTR1
YAP1- and WWTR1 (TAZ)-stimulated gene expression	CCN family member 2 Histone acetyltransferase KAT2B Homeobox protein Nkx-2.5 Homeodomain-interacting protein kinase 1 Homeodomain-interacting protein kinase 2 Natriuretic peptides A T-box transcription factor TBX5 Transcription factor GATA-4 Transcriptional coactivator YAP1 Transcriptional enhancer factor TEF-1 Transcriptional enhancer factor TEF-3 Transcriptional enhancer factor TEF-4 Transcriptional enhancer factor TEF-5 WW domain-containing transcription regulator protein 1	P01160 P28347 P29279 P43694 P46937 P52952 Q15561 Q15562 Q86Z02 Q92831 Q99593 Q99594 Q9GZV5 Q9H2X6	ANP CCN2 CSX CTGF GATA4 HCS24 HIPK1 HIPK2 IGFBP8 KAT2B KIAA0630 MYAK NBAK2 NKX2-5 NKX2.5 NKX2E NPPA PCAF PND RTEF1 TAZ TBX5 TCF13 TCF13L1 TEAD1 TEAD2 TEAD3 TEAD4 TEAD5 TEF1 TEF3 TEF4 TEF5 WWTR1 YAP1 YAP65
Vasopressin-like receptors	Oxytocin receptor Oxytocin-neurophysin 1 Vasopressin V1a receptor Vasopressin V1b receptor Vasopressin V2 receptor Vasopressin-neurophysin 2-copeptin	P01178 P01185 P30518 P30559 P37288 P47901	ADHR ARVP AVP AVPR1 AVPR1A AVPR1B AVPR2 AVPR3 DIR DIR3 OT OXT OXTR V2R VP VPR3
Defective AVP does not bind AVPR2 and causes neurohypophyseal diabetes insipidus (NDI)	Vasopressin V2 receptor Vasopressin-neurophysin 2-copeptin	P01185 P30518	ADHR ARVP AVP AVPR2 DIR DIR3 V2R VP
Defective AVP does not bind AVPR1A,B and causes neurohypophyseal diabetes insipidus (NDI)	Vasopressin V1a receptor Vasopressin V1b receptor Vasopressin-neurophysin 2-copeptin	P01185 P37288 P47901	ARVP AVP AVPR1 AVPR1A AVPR1B AVPR3 VP VPR3
Opioid Signalling	Mu-type opioid receptor Pro-opiomelanocortin Proenkephalin-B	P01189 P01213 P35372	MOR1 OPRM1 PDYN POMC
Androgen biosynthesis	17-beta-hydroxysteroid dehydrogenase type 3 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 3-oxo-5-alpha-steroid 4-dehydrogenase 1 3-oxo-5-alpha-steroid 4-dehydrogenase 2 Glycoprotein hormones alpha chain Lutropin subunit beta Polyprenol reductase Pro-opiomelanocortin Steroid 17-alpha-hydroxylase/17,20 lyase Very-long-chain 3-oxoacyl-CoA reductase	P01189 P01215 P01229 P05093 P14060 P18405 P26439 P31213 P37058 Q53GQ0 Q9H8P0	3BH CGA CYP17 CYP17A1 EDH17B3 HSD17B12 HSD17B3 HSD3B1 HSD3B2 HSDB3A HSDB3B LHB POMC S17AH SDR12C1 SDR12C2 SRD5A1 SRD5A2 SRD5A2L SRD5A3
Glucocorticoid biosynthesis	11-beta-hydroxysteroid dehydrogenase 1 11-beta-hydroxysteroid dehydrogenase type 2 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 Corticosteroid-binding globulin Cytochrome P450 11B1, mitochondrial Cytochrome P450 11B2, mitochondrial Pro-opiomelanocortin Steroid 17-alpha-hydroxylase/17,20 lyase Steroid 21-hydroxylase	P01189 P05093 P08185 P08686 P14060 P15538 P19099 P26439 P28845 P80365	3BH CBG CYP11B1 CYP11B2 CYP17 CYP17A1 CYP21 CYP21A2 CYP21B HSD11 HSD11B1 HSD11B2 HSD11K HSD11L HSD3B1 HSD3B2 HSDB3A HSDB3B POMC S11BH S17AH SDR26C1 SDR9C3 SERPINA6
Peptide hormone biosynthesis	Neuroendocrine convertase 1 Pro-opiomelanocortin	P01189 P29120	NEC1 PCSK1 POMC

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