GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1251 - 1275** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism
Formation of apoptosome	Apoptotic protease-activating factor 1 Caspase recruitment domain-containing protein 8 Caspase-9 Cell death regulator Aven Cytochrome c Methylthioribulose-1-phosphate dehydratase	O14727 P55211 P99999 Q96GX9 Q9NQS1 Q9Y2G2	APAF1 APIP AVEN CARD8 CASP9 CYC CYCS DACAR KIAA0413 KIAA0955 MCH6 NDPP1	Homo sapiens (human)
Activation of caspases through apoptosome-mediated cleavage	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS IAP3 KIAA0413 MCH3 MCH6 XIAP	Homo sapiens (human)
SMAC (DIABLO) binds to IAPs	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999 Q9NR28	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS DIABLO IAP3 KIAA0413 MCH3 MCH6 SMAC XIAP	Homo sapiens (human)
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999 Q9NR28	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS DIABLO IAP3 KIAA0413 MCH3 MCH6 SMAC XIAP	Homo sapiens (human)
Regulation of the apoptosome activity	Apoptotic protease-activating factor 1 Caspase recruitment domain-containing protein 8 Caspase-9 Cell death regulator Aven Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP Methylthioribulose-1-phosphate dehydratase Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Uveal autoantigen with coiled-coil domains and ankyrin repeats	O14727 P27361 P28482 P55211 P98170 P99999 Q96GX9 Q9BZF9 Q9NQS1 Q9NR28 Q9Y2G2	APAF1 API3 APIP AVEN BIRC4 CARD8 CASP9 CYC CYCS DACAR DIABLO ERK1 ERK2 IAP3 KIAA0413 KIAA0955 KIAA1561 MAPK1 MAPK3 MCH6 NDPP1 PRKM1 PRKM2 PRKM3 SMAC UACA XIAP	Homo sapiens (human)
Activation of the TFAP2 (AP-2) family of transcription factors	CREB-binding protein Cbp/p300-interacting transactivator 1 Cbp/p300-interacting transactivator 2 Cbp/p300-interacting transactivator 4 Histone acetyltransferase p300 Transcription factor AP-2 gamma Transcription factor AP-2-alpha Transcription factor AP-2-beta Transcription factor AP-2-delta Transcription factor AP-2-epsilon WW domain-containing oxidoreductase YEATS domain-containing protein 4	O95619 P05549 Q09472 Q6VUC0 Q7Z6R9 Q92481 Q92754 Q92793 Q96RK1 Q99966 Q99967 Q9NZC7	AP2TF CBP CITED1 CITED2 CITED4 CREBBP EP300 FOR GAS41 MRG1 MRG2 MSG1 P300 SDR41C1 TFAP2 TFAP2A TFAP2B TFAP2BL1 TFAP2C TFAP2D TFAP2E WOX1 WWOX YEATS4	Homo sapiens (human)
Negative regulation of activity of TFAP2 (AP-2) family transcription factors	BTB/POZ domain-containing protein KCTD15 BTB/POZ domain-containing protein KCTD1 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Transcription factor AP-2 gamma Transcription factor AP-2-alpha Transcription factor AP-2-beta Transcription factor AP-2-delta Transcription factor AP-2-epsilon WW domain-containing oxidoreductase	P05549 P63165 P63279 Q6VUC0 Q719H9 Q7Z6R9 Q92481 Q92754 Q96SI1 Q9NZC7	AP2TF C18orf5 FOR KCTD1 KCTD15 SDR41C1 SMT3C SMT3H3 SUMO1 TFAP2 TFAP2A TFAP2B TFAP2BL1 TFAP2C TFAP2D TFAP2E UBC9 UBCE9 UBE2I UBL1 WOX1 WWOX	Homo sapiens (human)
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation	60 kDa heat shock protein, mitochondrial Myb-related protein B Nucleophosmin Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase Transcription factor AP-2-alpha	P05549 P06748 P10244 P10809 P46087	AP2TF BMYB HSP60 HSPD1 MYBL2 NOL1 NOP2 NPM NPM1 NSUN1 TFAP2 TFAP2A	Homo sapiens (human)
Specification of the neural plate border	Bone morphogenetic protein 4 Catenin beta-1 Fibroblast growth factor 4 Homeobox protein DLX-5 Homeobox protein GBX-2 Homeobox protein MSX-1 POU domain, class 5, transcription factor 1 Paired box protein Pax-3 Paired box protein Pax-7 Protein Wnt-3a Transcription factor 7-like 1 Transcription factor AP-2 gamma Transcription factor AP-2-alpha Transcription factor AP-2-beta Transcription factor SOX-2 Transcriptional activator Myb Zinc finger protein ZIC 1	P05549 P08620 P10242 P12644 P23759 P23760 P28360 P35222 P48431 P52951 P56178 P56704 Q01860 Q15915 Q92481 Q92754 Q9HCS4	AP2TF BMP2B BMP4 CTNNB CTNNB1 DLX5 DVR4 FGF4 GBX2 HOX7 HST HSTF1 HUP1 HUP2 KS3 MSX1 MYB OCT3 OCT4 OTF3 PAX3 PAX7 POU5F1 SOX2 TCF3 TCF7L1 TFAP2 TFAP2A TFAP2B TFAP2C WNT3A ZIC ZIC1 ZNF201	Homo sapiens (human)
TFAP2 (AP-2) family regulates transcription of cell cycle factors	Cyclin-dependent kinase inhibitor 1 Lysine-specific demethylase 5B Myc proto-oncogene protein Transcription factor AP-2 gamma Transcription factor AP-2-alpha	P01106 P05549 P38936 Q92754 Q9UGL1	AP2TF BHLHE39 CAP20 CDKN1 CDKN1A CIP1 JARID1B KDM5B MDA6 MYC PIC1 PLU1 RBBP2H1 SDI1 TFAP2 TFAP2A TFAP2C WAF1	Homo sapiens (human)
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	ATPase family AAA domain-containing protein 2 Choriogonadotropin subunit beta 3 Epidermal growth factor receptor Estrogen receptor Glycoprotein hormones alpha chain Mast/stem cell growth factor receptor Kit Protransforming growth factor alpha Receptor tyrosine-protein kinase erbB-2 Transcription factor AP-2 gamma Transcription factor AP-2-alpha Transcription factor AP-2-beta Transcriptional repressor protein YY1 Vascular endothelial growth factor A, long form	P00533 P01135 P01215 P03372 P04626 P05549 P0DN86 P10721 P15692 P25490 Q6PL18 Q92481 Q92754	AP2TF ATAD2 CGA CGB CGB3 CGB5 CGB8 EGFR ERBB ERBB1 ERBB2 ESR ESR1 HER1 HER2 INO80S KIT MLN19 NEU NGL NR3A1 SCFR TFAP2 TFAP2A TFAP2B TFAP2C TGFA VEGF VEGFA YY1	Homo sapiens (human)
TFAP2 (AP-2) family regulates transcription of other transcription factors	Cbp/p300-interacting transactivator 2 Pituitary homeobox 2 Transcription factor AP-2 gamma Transcription factor AP-2-alpha	P05549 Q92754 Q99697 Q99967	AP2TF ARP1 CITED2 MRG1 PITX2 RGS RIEG RIEG1 TFAP2 TFAP2A TFAP2C	Homo sapiens (human)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	Apolipoprotein E Protein DEK Transcription factor AP-2-alpha	P02649 P05549 P35659	AP2TF APOE DEK TFAP2 TFAP2A	Homo sapiens (human)
Formation of annular gap junctions	AP-2 complex subunit mu Clathrin heavy chain 1 Clathrin heavy chain 2 Clathrin light chain A Clathrin light chain B Disabled homolog 2 Dynamin-1 Dynamin-2 Gap junction alpha-1 protein	P09496 P09497 P17302 P50570 P53675 P98082 Q00610 Q05193 Q96CW1	AP2M1 CLAPM1 CLH17 CLH22 CLTA CLTB CLTC CLTCL CLTCL1 CLTCL2 CLTD DAB2 DNM DNM1 DNM2 DOC2 DYN2 GJA1 GJAL KIAA0034 KIAA0109	Homo sapiens (human)
Gap junction degradation	AP-2 complex subunit mu Clathrin heavy chain 1 Clathrin heavy chain 2 Clathrin light chain A Clathrin light chain B Disabled homolog 2 Dynamin-1 Dynamin-2 Gap junction alpha-1 protein Unconventional myosin-VI	P09496 P09497 P17302 P50570 P53675 P98082 Q00610 Q05193 Q96CW1 Q9UM54	AP2M1 CLAPM1 CLH17 CLH22 CLTA CLTB CLTC CLTCL CLTCL1 CLTCL2 CLTD DAB2 DNM DNM1 DNM2 DOC2 DYN2 GJA1 GJAL KIAA0034 KIAA0109 KIAA0389 MYO6	Homo sapiens (human)
Nef mediated downregulation of CD28 cell surface expression	AP-2 complex subunit mu Protein Nef T-cell-specific surface glycoprotein CD28	P04601 P10747 Q96CW1	AP2M1 CD28 CLAPM1 KIAA0109 nef	Homo sapiens (human)
SUMO is conjugated to E1 (UBA2:SAE1)	SUMO-activating enzyme subunit 1 SUMO-activating enzyme subunit 2 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3	P55854 P61956 P63165 Q9UBE0 Q9UBT2	AOS1 SAE1 SAE2 SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SUA1 SUMO1 SUMO2 SUMO3 UBA2 UBL1 UBLE1A UBLE1B	Homo sapiens (human)
SUMO is transferred from E1 to E2 (UBE2I, UBC9)	RWD domain-containing protein 3 SUMO-activating enzyme subunit 1 SUMO-activating enzyme subunit 2 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3	P55854 P61956 P63165 P63279 Q9UBE0 Q9UBT2 Q9Y3V2	AOS1 RSUME RWDD3 SAE1 SAE2 SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SUA1 SUMO1 SUMO2 SUMO3 UBA2 UBC9 UBCE9 UBE2I UBL1 UBLE1A UBLE1B	Homo sapiens (human)
Detoxification of Reactive Oxygen Species	Aquaporin-8 Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] Catalase Copper chaperone for superoxide dismutase Copper transport protein ATOX1 Copper-transporting ATPase 1 Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytochrome c ERO1-like protein alpha Epididymal secretory glutathione peroxidase Extracellular superoxide dismutase [Cu-Zn] Glutathione S-transferase P Glutathione peroxidase 1 Glutathione peroxidase 2 Glutathione peroxidase 3 Glutathione peroxidase 6 Glutathione peroxidase 7 NADPH oxidase 4 NADPH oxidase 5 Neutrophil cytosol factor 1 Neutrophil cytosol factor 2 Neutrophil cytosol factor 4 Peroxiredoxin-1 Peroxiredoxin-2 Peroxiredoxin-6 Probable glutathione peroxidase 8 Protein disulfide-isomerase Superoxide dismutase [Cu-Zn] Superoxide dismutase [Mn], mitochondrial Thioredoxin reductase 1, cytoplasmic Thioredoxin reductase 2, mitochondrial Thioredoxin, mitochondrial Thioredoxin-dependent peroxide reductase, mitochondrial Thioredoxin	O00244 O14618 O75715 O94778 P00441 P04040 P04179 P04839 P07203 P07237 P08294 P09211 P10599 P13498 P14598 P18283 P19878 P22352 P30041 P30048 P32119 P50583 P59796 P99999 Q04656 Q06830 Q15080 Q16881 Q8TED1 Q96HE7 Q96PH1 Q96SL4 Q99757 Q9NNW7 Q9NPH5	AOP1 AOP2 APAH1 AQP8 ATOX1 ATP7A CAT CCS CYBA CYBB CYC CYCS ERBA2L ERO1A ERO1L FAEES3 GPX1 GPX2 GPX3 GPX5 GPX6 GPX7 GPX8 GPXP GRIM12 GST3 GSTP1 HAH1 KDRF KIAA0106 KIAA1652 MC1 MNK NCF1 NCF2 NCF4 NKEFB NOX2 NOX4 NOX5 NOXA2 NOXO2 NUDT2 P4HB P67PHOX PAGA PAGB PDI PDIA1 PO4DB PRDX1 PRDX2 PRDX3 PRDX6 RENOX SH3PXD1A SH3PXD4 SOD1 SOD2 SOD3 TDPX1 TDPX2 TRDX TRX TRX1 TRX2 TRXR2 TXN TXN2 TXNRD1 TXNRD2	Homo sapiens (human)
Regulation of PTEN gene transcription	Atrophin-1 Cellular tumor antigen p53 Chromobox protein homolog 2 Chromobox protein homolog 6 Chromobox protein homolog 8 Chromodomain-helicase-DNA-binding protein 3 Chromodomain-helicase-DNA-binding protein 4 Cyclic AMP-dependent transcription factor ATF-2 E3 SUMO-protein ligase CBX4 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 Early growth response protein 1 GTP-binding protein Rheb Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 5 Histone deacetylase 7 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase EZH2 Histone-lysine N-methyltransferase MECOM Lysine-specific histone demethylase 1A Metastasis-associated protein MTA1 Metastasis-associated protein MTA2 Metastasis-associated protein MTA3 Methyl-CpG-binding domain protein 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Neutral amino acid transporter 9 Nuclear receptor subfamily 2 group E member 1 Peroxisome proliferator-activated receptor gamma Polycomb complex protein BMI-1 Polycomb protein EED Polycomb protein SUZ12 Polyhomeotic-like protein 1 Polyhomeotic-like protein 2 Polyhomeotic-like protein 3 RE1-silencing transcription factor REST corepressor 1 Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR Repressor of RNA polymerase III transcription MAF1 homolog Sal-like protein 4 Serine/threonine-protein kinase mTOR Target of rapamycin complex subunit LST8 Transcription factor Jun Transcriptional repressor p66-alpha Transcriptional repressor p66-beta Zinc finger protein SNAI1 Zinc finger protein SNAI2	O00257 O15379 O43504 O43623 O60341 O75530 O94776 O95503 O95863 O95983 P04637 P05412 P15336 P18146 P27361 P28482 P35226 P37231 P42345 P54259 P78364 Q03112 Q06587 Q09028 Q0VGL1 Q12873 Q13127 Q13330 Q13547 Q14781 Q14839 Q15022 Q15382 Q15910 Q16576 Q5VZM2 Q6IAA8 Q7L523 Q86YP4 Q8IXK0 Q8N122 Q8NBW4 Q8NDX5 Q8WUI4 Q8WXI9 Q92769 Q99496 Q9BTC8 Q9BVC4 Q9H063 Q9HB90 Q9HC52 Q9NQL2 Q9UHA4 Q9UJQ4 Q9UKL0 Q9UQL6 Q9Y2Q5 Q9Y466	AOF2 ATF2 ATN1 BAP1 BMI1 C11orf59 C7orf59 CBX2 CBX4 CBX6 CBX8 CHD3 CHD4 CHET9 CREB2 CREBP1 D12S755E DING DRPLA EDR1 EDR2 EDR3 EED EGR1 ERK1 ERK2 EVI1 EZH2 FRAP FRAP1 FRAP2 GATAD2A GATAD2B GBL HBXIP HDAC1 HDAC2 HDAC3 HDAC5 HDAC7 HDAC7A HIPI3 JJAZ1 JUN KDM1 KDM1A KIAA0071 KIAA0160 KIAA0600 KIAA0601 KIAA1150 KIAA1266 KIAA1303 KMT6 KROX24 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LSD1 LST8 MAF1 MAP2K1IP1 MAPBPIP MAPK1 MAPK3 MAPKSP1 MBD3 MDS1 MECOM MLST8 MTA1 MTA1L1 MTA2 MTA3 MTOR NR1C3 NR2E1 NRSF P53 PC3 PCGF4 PDRO PH1 PH2 PH3 PHC1 PHC2 PHC3 PID PPARG PRDM3 PRKM1 PRKM2 PRKM3 RAFT1 RAPT1 RAPTOR RBAP46 RBAP48 RBBP4 RBBP7 RC1 RCOR RCOR1 REST RHEB RHEB2 RING1 RING1A RING1B RNF1 RNF2 RNF51 ROBLD3 RPD3L1 RPTOR RRAGA RRAGB RRAGC RRAGD SALL4 SLC38A9 SLUG SLUGH SNAH SNAI1 SNAI2 SUZ12 TLX TP53 URLC11 XBR XIP ZNF225 ZNF797	Homo sapiens (human)
HDACs deacetylate histones	AT-rich interactive domain-containing protein 4A AT-rich interactive domain-containing protein 4B Breast cancer metastasis-suppressor 1 Chromodomain-helicase-DNA-binding protein 3 Chromodomain-helicase-DNA-binding protein 4 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 G protein pathway suppressor 2 Histone H2A type 1-A Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-H Histone H2A type 1-J Histone H2A type 1 Histone H2A type 2-A Histone H2A type 2-B Histone H2A type 2-C Histone H2A type 3 Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 2-F Histone H2B type 3-B Histone H3.1 Histone H3.2 Histone H4 Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 8 Histone deacetylase complex subunit SAP18 Histone deacetylase complex subunit SAP30 Histone deacetylase complex subunit SAP30L Histone-binding protein RBBP4 Histone-binding protein RBBP7 Lysine-specific histone demethylase 1A Metastasis-associated protein MTA1 Metastasis-associated protein MTA2 Metastasis-associated protein MTA3 Methyl-CpG-binding domain protein 3 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 PHD finger protein 21A Polyamine deacetylase HDAC10 RE1-silencing transcription factor REST corepressor 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related Sin3 histone deacetylase corepressor complex component SDS3 Transcriptional repressor p66-alpha Transcriptional repressor p66-beta	O00422 O15379 O60341 O60814 O60907 O75376 O75446 O94776 O95983 P04908 P06899 P0C0S8 P20671 P23527 P29374 P33778 P58876 P62805 P62807 P68431 Q09028 Q12873 Q13127 Q13227 Q13330 Q13547 Q14839 Q16576 Q16777 Q16778 Q4LE39 Q5QNW6 Q6FI13 Q71DI3 Q7L7L0 Q86YP4 Q8IUE6 Q8N257 Q8WXI9 Q92769 Q93077 Q93079 Q969S8 Q96A08 Q96BD5 Q96KK5 Q96QV6 Q99877 Q99878 Q99879 Q99880 Q9BTC8 Q9BY41 Q9BZK7 Q9H7L9 Q9HAJ7 Q9HCU9 Q9P0W2 Q9UKL0 Q9Y618	AOF2 ARID4A ARID4B BHC80 BRAF35 BRCAA1 BRMS1 CHD3 CHD4 CTG26 GATAD2A GATAD2B GPS2 H2AC1 H2AC11 H2AC12 H2AC13 H2AC14 H2AC15 H2AC16 H2AC17 H2AC18 H2AC19 H2AC20 H2AC21 H2AC25 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFC H2AFD H2AFE H2AFG H2AFI H2AFL H2AFM H2AFN H2AFO H2AFP H2AFQ H2AFR H2AW H2BC1 H2BC10 H2BC11 H2BC12 H2BC13 H2BC14 H2BC15 H2BC17 H2BC18 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFT H2BU1 H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HDAC1 HDAC10 HDAC2 HDAC3 HDAC8 HDACL1 HIRIP1 HIRIP2 HIST1H2AA HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AG HIST1H2AH HIST1H2AI HIST1H2AJ HIST1H2AK HIST1H2AL HIST1H2AM HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AB HIST2H2AC HIST2H2BE HIST2H2BF HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2A HIST3H2BB HIST4H4 HMG20B HMGX2 HMGXB2 IRA1 KDM1 KDM1A KIAA0071 KIAA0601 KIAA1047 KIAA1150 KIAA1266 KIAA1696 LSD1 MBD3 MTA1 MTA1L1 MTA2 MTA3 NCOR1 NCOR2 NRSF NS4ATP2 PHF21A PID RBAP46 RBAP48 RBBP1 RBBP1L1 RBBP4 RBBP7 RBP1 RBP1L1 RCOR RCOR1 REST RPD3L1 SAP18 SAP180 SAP30 SAP30L SAP45 SDS3 SMARCE1R SUDS3 TBL1 TBL1X TBL1XR1 TBLR1 TSH2B XBR	Homo sapiens (human)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	Androgen receptor Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Kallikrein-2 Lysine-specific demethylase 4C Lysine-specific histone demethylase 1A Nuclear receptor coactivator 2 Prostate-specific antigen Serine/threonine-protein kinase N1	O60341 O60814 P04908 P06899 P07288 P0C5Y9 P10275 P16104 P20151 P20671 P23527 P33778 P57053 P58876 P62805 P62807 P68431 P84243 Q15596 Q16512 Q16777 Q16778 Q6FI13 Q71DI3 Q71UI9 Q8N257 Q93077 Q93079 Q96A08 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9H3R0	AOF2 APS AR BHLHE75 DHTR GASC1 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 JHDM3C JMJD2C KDM1 KDM1A KDM4C KIAA0601 KIAA0780 KLK2 KLK3 LSD1 NCOA2 NR3C4 PAK1 PKN PKN1 PRK1 PRKCL1 SRC2 TIF2 TSH2B	Homo sapiens (human)
HDMs demethylate histones	AT-rich interactive domain-containing protein 5B Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 Histone H3.1 Histone H3.2 Histone H4 Histone demethylase UTY Histone lysine demethylase PHF8 Lysine-specific demethylase 2A Lysine-specific demethylase 2B Lysine-specific demethylase 3A Lysine-specific demethylase 3B Lysine-specific demethylase 4A Lysine-specific demethylase 4B Lysine-specific demethylase 4C Lysine-specific demethylase 4D Lysine-specific demethylase 5A Lysine-specific demethylase 5B Lysine-specific demethylase 5C Lysine-specific demethylase 5D Lysine-specific demethylase 6A Lysine-specific demethylase 6B Lysine-specific demethylase 7A Lysine-specific demethylase PHF2 Lysine-specific histone demethylase 1A Lysine-specific histone demethylase 2 Ribosomal oxygenase 2	O14607 O15054 O15550 O60341 O75151 O75164 O94953 P29375 P41229 P62805 P68431 Q14865 Q6B0I6 Q6NYC1 Q6ZMT4 Q71DI3 Q7LBC6 Q8IUF8 Q8NB78 Q8NHM5 Q9BY66 Q9H3R0 Q9UGL1 Q9UPP1 Q9Y2K7 Q9Y4C1	AOF1 AOF2 ARID5B C5orf7 C6orf193 CENP-35 CXXC2 CXXC8 DESRT DXS1272E FBL10 FBL11 FBL7 FBXL10 FBXL11 GASC1 H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST4H4 HY HYA JARID1A JARID1B JARID1C JARID1D JHDM1A JHDM1B JHDM1D JHDM2A JHDM2B JHDM3A JHDM3B JHDM3C JHDM3D JMJD1 JMJD1A JMJD1B JMJD2 JMJD2A JMJD2B JMJD2C JMJD2D JMJD3 JMJD6 KDM1 KDM1A KDM1B KDM2A KDM2B KDM3A KDM3B KDM4A KDM4B KDM4C KDM4D KDM5A KDM5B KDM5C KDM5D KDM6A KDM6B KDM6C KDM7 KDM7A KIAA0234 KIAA0346 KIAA0585 KIAA0601 KIAA0662 KIAA0677 KIAA0742 KIAA0780 KIAA0876 KIAA1004 KIAA1082 KIAA1111 KIAA1718 LSD1 LSD2 MDIG MINA MINA53 MRF2 NDY1 NO52 PCCX2 PHF2 PHF8 PLU1 PSR PTDSR RBBP2 RBBP2H1 RBP2 RIOX2 SMCX SMCY TSGA UTX UTY XE169 ZNF422	Homo sapiens (human)
Vitamin B6 activation to pyridoxal phosphate	Aldehyde oxidase Pyridoxal kinase Pyridoxine-5'-phosphate oxidase	O00764 Q06278 Q9NVS9	AO AOX1 C21orf124 C21orf97 PDXK PKH PNK PNPO	Homo sapiens (human)
HuR (ELAVL1) binds and stabilizes mRNA	Acidic leucine-rich nuclear phosphoprotein 32 family member A ELAV-like protein 1 Exportin-1 Nuclear pore complex protein Nup214 Protein SET Protein kinase C alpha type Protein kinase C delta type Tumor necrosis factor ligand superfamily member 13	O14980 O75888 P17252 P35658 P39687 Q01105 Q05655 Q15717	ANP32A APRIL C15orf1 CAIN CAN CRM1 ELAVL1 HUR KIAA0023 LANP MAPM NUP214 PHAP1 PKCA PKCD PRKACA PRKCA PRKCD SET TALL2 TNFSF13 XPO1 ZTNF2	Homo sapiens (human)

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