GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1451 - 1475** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism
Defective VWF cleavage by ADAMTS13 variant	A disintegrin and metalloproteinase with thrombospondin motifs 13 von Willebrand factor	P04275 Q76LX8	ADAMTS13 C9orf8 F8VWF VWF	Homo sapiens (human)
Enhanced cleavage of VWF variant by ADAMTS13	A disintegrin and metalloproteinase with thrombospondin motifs 13 von Willebrand factor	P04275 Q76LX8	ADAMTS13 C9orf8 F8VWF VWF	Homo sapiens (human)
Defective VWF binding to collagen type I	von Willebrand factor	P04275	F8VWF VWF	Homo sapiens (human)
Assembly Of The HIV Virion	Envelope glycoprotein gp160 Gag polyprotein Gag-Pol polyprotein Peptidyl-prolyl cis-trans isomerase A Polyubiquitin-B Polyubiquitin-C Protein Nef Protein Rev Protein Vpr Protein Vpu Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Virion infectivity factor	P04578 P04585 P04591 P04601 P04618 P05919 P0CG47 P0CG48 P62937 P62979 P62987 P69723 P69726	CYPA PPIA RPS27A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 env gag gag-pol nef rev vif vpr vpu	Homo sapiens (human)
Synthesis and processing of ENV and VPU	Envelope glycoprotein gp160 Furin Protein Vpu	P04578 P05919 P09958	FUR FURIN PACE PCSK3 env vpu	Homo sapiens (human)
Uncoating of the HIV Virion	Gag polyprotein Gag-Pol polyprotein Peptidyl-prolyl cis-trans isomerase A Protein Nef Protein Rev Protein Vpr Protein Vpu Virion infectivity factor	P04585 P04591 P04601 P04618 P05919 P62937 P69723 P69726	CYPA PPIA gag gag-pol nef rev vif vpr vpu	Homo sapiens (human)
Early Phase of HIV Life Cycle	DNA ligase 1 Flap endonuclease 1 Gag polyprotein Gag-Pol polyprotein Peptidyl-prolyl cis-trans isomerase A Protein Rev Protein Vpr Protein Vpu Virion infectivity factor	P04585 P04591 P04618 P05919 P18858 P39748 P62937 P69723 P69726	CYPA FEN1 LIG1 PPIA RAD2 gag gag-pol rev vif vpr vpu	Homo sapiens (human)
Minus-strand DNA synthesis	Gag polyprotein Gag-Pol polyprotein Peptidyl-prolyl cis-trans isomerase A Protein Rev Protein Vpr Protein Vpu Virion infectivity factor	P04585 P04591 P04618 P05919 P62937 P69723 P69726	CYPA PPIA gag gag-pol rev vif vpr vpu	Homo sapiens (human)
Plus-strand DNA synthesis	Gag polyprotein Gag-Pol polyprotein Peptidyl-prolyl cis-trans isomerase A Protein Rev Protein Vpr Protein Vpu Virion infectivity factor	P04585 P04591 P04618 P05919 P62937 P69723 P69726	CYPA PPIA gag gag-pol rev vif vpr vpu	Homo sapiens (human)
Synthesis And Processing Of GAG, GAGPOL Polyproteins	Gag polyprotein	P04591	gag	Homo sapiens (human)
Nef and signal transduction	Dedicator of cytokinesis protein 2 Engulfment and cell motility protein 1 Protein Nef Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 2 Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lck	P04601 P06239 P06241 P08631 P63000 Q13177 Q92556 Q92608	DOCK2 ELMO1 FYN HCK KIAA0209 KIAA0281 LCK PAK2 RAC1 TC25 nef	Homo sapiens (human)
Nef mediated downregulation of CD28 cell surface expression	AP-2 complex subunit mu Protein Nef T-cell-specific surface glycoprotein CD28	P04601 P10747 Q96CW1	AP2M1 CD28 CLAPM1 KIAA0109 nef	Homo sapiens (human)
Late Phase of HIV Life Cycle	Glycylpeptide N-tetradecanoyltransferase 1 Protein Nef	P04601 P30419	NMT NMT1 nef	Homo sapiens (human)
Resistance of ERBB2 KD mutants to lapatinib	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL	Homo sapiens (human)
Resistance of ERBB2 KD mutants to sapitinib	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL	Homo sapiens (human)
Resistance of ERBB2 KD mutants to AEE788	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL	Homo sapiens (human)
Drug-mediated inhibition of ERBB2 signaling	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL	Homo sapiens (human)
Resistance of ERBB2 KD mutants to tesevatinib	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL	Homo sapiens (human)
Drug resistance in ERBB2 TMD/JMD mutants	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL	Homo sapiens (human)
Resistance of ERBB2 KD mutants to trastuzumab	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL	Homo sapiens (human)
Resistance of ERBB2 KD mutants to afatinib	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL	Homo sapiens (human)
Resistance of ERBB2 KD mutants to neratinib	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL	Homo sapiens (human)
Resistance of ERBB2 KD mutants to osimertinib	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL	Homo sapiens (human)
NGF-independant TRKA activation	Adenosine receptor A2a BDNF/NT-3 growth factors receptor High affinity nerve growth factor receptor Pituitary adenylate cyclase-activating polypeptide type I receptor Pituitary adenylate cyclase-activating polypeptide	P04629 P18509 P29274 P41586 Q16620	ADCYAP1 ADCYAP1R1 ADORA2 ADORA2A MTC NTRK1 NTRK2 TRK TRKA TRKB	Homo sapiens (human)
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	Calcineurin-binding protein cabin-1 Cellular tumor antigen p53 E1A-binding protein p400 High mobility group protein HMG-I/HMG-Y High mobility group protein HMGI-C Histone H1.0 Histone H1.1 Histone H1.2 Histone H1.3 Histone H1.4 Histone H1.5 Histone chaperone ASF1A Lamin-B1 Protein HIRA Retinoblastoma-associated protein Ubinuclein-1	P04637 P06400 P07305 P10412 P16401 P16402 P16403 P17096 P20700 P52926 P54198 Q02539 Q96L91 Q9NPG3 Q9Y294 Q9Y6J0	ASF1A CABIN1 CAGH32 DGCR1 EP400 H1-0 H1-1 H1-2 H1-3 H1-4 H1-5 H1F0 H1F1 H1F2 H1F3 H1F4 H1F5 H1FV HIR HIRA HIST1H1A HIST1H1B HIST1H1C HIST1H1D HIST1H1E HMGA1 HMGA2 HMGIC HMGIY KIAA0330 KIAA1498 KIAA1818 LMN2 LMNB LMNB1 P53 RB1 TNRC12 TP53 TUPLE1 UBN1	Homo sapiens (human)

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