GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1976 - 2000** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
Defective ABCC8 can cause hypo- and hyper-glycemias	ATP-binding cassette sub-family C member 8 ATP-sensitive inward rectifier potassium channel 11	Q09428 Q14654	ABCC8 HRINS KCNJ11 SUR SUR1	Homo sapiens (human)
Defective MGAT2 causes CDG-2a	Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Q10469	MGAT2	Homo sapiens (human)
Acetylcholine inhibits contraction of outer hair cells	Calcium-activated potassium channel subunit alpha-1 Calcium-activated potassium channel subunit beta-1 Neuronal acetylcholine receptor subunit alpha-10 Neuronal acetylcholine receptor subunit alpha-9 Small conductance calcium-activated potassium channel protein 2	Q12791 Q16558 Q9GZZ6 Q9H2S1 Q9UGM1	CHRNA10 CHRNA9 KCNMA KCNMA1 KCNMB1 KCNN2 NACHRA10 NACHRA9 SLO	Homo sapiens (human)
MPS IX - Natowicz syndrome	Hyaluronidase-1	Q12794	HYAL1 LUCA1	Homo sapiens (human)	G35674CY
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	Cell division cycle protein 20 homolog Mitotic spindle assembly checkpoint protein MAD2A	Q12834 Q13257	CDC20 MAD2 MAD2L1	Homo sapiens (human)
Defective RIPK1-mediated regulated necrosis	Caspase-8 FAS-associated death domain protein Receptor-interacting serine/threonine-protein kinase 1 TNF receptor-associated factor 2 Tumor necrosis factor receptor type 1-associated DEATH domain protein	Q12933 Q13158 Q13546 Q14790 Q15628	CASP8 FADD MCH5 MORT1 RIP RIP1 RIPK1 TRADD TRAF2 TRAP3	Homo sapiens (human)
Coenzyme A biosynthesis	Bifunctional coenzyme A synthase Dephospho-CoA kinase domain-containing protein Pantothenate kinase 1 Pantothenate kinase 2, mitochondrial Pantothenate kinase 3 Phosphopantothenate--cysteine ligase Phosphopantothenoylcysteine decarboxylase	Q13057 Q8TE04 Q8WVC6 Q96CD2 Q9BZ23 Q9H999 Q9HAB8	C20orf48 COAB COAC COASY DCAKD PANK PANK1 PANK2 PANK3 PPCDC PPCS	Homo sapiens (human)
Signalling to ERK5	Dual specificity mitogen-activated protein kinase kinase 5 Mitogen-activated protein kinase 7	Q13163 Q13164	BMK1 ERK5 MAP2K5 MAPK7 MEK5 MKK5 PRKM7 PRKMK5	Homo sapiens (human)
Sodium-coupled sulphate, di- and tri-carboxylate transporters	Na(+)/citrate cotransporter Na(+)/dicarboxylate cotransporter 3 Solute carrier family 13 member 1 Solute carrier family 13 member 2 Solute carrier family 13 member 4	Q13183 Q86YT5 Q8WWT9 Q9BZW2 Q9UKG4	NACT NADC1 NADC3 NAS1 NASI1 SDCT1 SDCT2 SLC13A1 SLC13A2 SLC13A3 SLC13A4 SLC13A5 SUT1	Homo sapiens (human)
Leukotriene receptors	Cysteinyl leukotriene receptor 1 Cysteinyl leukotriene receptor 2 Leukotriene B4 receptor 1 Leukotriene B4 receptor 2 Uracil nucleotide/cysteinyl leukotriene receptor	Q13304 Q15722 Q9NPC1 Q9NS75 Q9Y271	BLT BLT1 BLT2R BLTR BLTR2 CMKRL1 CYSLT1 CYSLT2 CYSLT2R CYSLTR1 CYSLTR2 GPR16 GPR17 LTB4R LTB4R2 P2RY7	Homo sapiens (human)
Transport of bile salts and organic acids, metal ions and amine compounds	Choline transporter-like protein 1 Choline transporter-like protein 2 Choline transporter-like protein 3 Choline transporter-like protein 4 Choline transporter-like protein 5 High affinity choline transporter 1 Multidrug and toxin extrusion protein 1 Multidrug and toxin extrusion protein 2 Sodium-dependent organic anion transporter Urea transporter 1 Urea transporter 2	Q13336 Q15849 Q3KNW5 Q53GD3 Q86VL8 Q8IWA5 Q8N4M1 Q8NCS7 Q8WWI5 Q96FL8 Q9GZV3	C6orf29 CD92 CDW92 CHT1 CTL1 CTL2 CTL3 CTL4 CTL5 HUT11 HUT2 JK MATE1 MATE2 NG22 RACH1 SLC10A6 SLC14A1 SLC14A2 SLC44A1 SLC44A2 SLC44A3 SLC44A4 SLC44A5 SLC47A1 SLC47A2 SLC5A7 SOAT TPPT1 UT1 UT2 UTE	Homo sapiens (human)
Zinc influx into cells by the SLC39 gene family	Metal cation symporter ZIP14 Metal cation symporter ZIP8 Zinc transporter SLC39A7 Zinc transporter ZIP10 Zinc transporter ZIP1 Zinc transporter ZIP2 Zinc transporter ZIP3 Zinc transporter ZIP4 Zinc transporter ZIP5 Zinc transporter ZIP6	Q13433 Q15043 Q6P5W5 Q6ZMH5 Q92504 Q9BRY0 Q9C0K1 Q9NP94 Q9NY26 Q9ULF5	BIGM103 HKE4 IRT1 KIAA0062 KIAA1265 LIV1 RING5 SLC39A1 SLC39A10 SLC39A14 SLC39A2 SLC39A3 SLC39A4 SLC39A5 SLC39A6 SLC39A7 SLC39A8 ZIP1 ZIP10 ZIP14 ZIP2 ZIP3 ZIP4 ZIP5 ZIP6 ZIP8 ZIRTL	Homo sapiens (human)
Loss of MECP2 binding ability to 5mC-DNA	Histone deacetylase 1 Paired amphipathic helix protein Sin3a	Q13547 Q96ST3	HDAC1 RPD3L1 SIN3A	Homo sapiens (human)
Defective SLC12A1 causes Bartter syndrome 1 (BS1)	Solute carrier family 12 member 1	Q13621	NKCC2 SLC12A1	Homo sapiens (human)
Defective MOGS causes CDG-2b	Mannosyl-oligosaccharide glucosidase	Q13724	GCS1 MOGS	Homo sapiens (human)
RUNX3 regulates RUNX1-mediated transcription	Core-binding factor subunit beta Runt-related transcription factor 3	Q13761 Q13951	AML2 CBFA3 CBFB PEBP2A3 RUNX3	Homo sapiens (human)
Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3	Dystroglycan 1 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1	Q14118 Q8WZA1	DAG1 MGAT1.2 POMGNT1	Homo sapiens (human)
Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1	Dystroglycan 1 Protein O-mannosyl-transferase 1 Protein O-mannosyl-transferase 2	Q14118 Q9UKY4 Q9Y6A1	DAG1 POMT1 POMT2	Homo sapiens (human)
Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2	Dystroglycan 1 Protein O-mannosyl-transferase 1 Protein O-mannosyl-transferase 2	Q14118 Q9UKY4 Q9Y6A1	DAG1 POMT1 POMT2	Homo sapiens (human)
Defective GALE causes EDG	UDP-glucose 4-epimerase	Q14376	GALE	Homo sapiens (human)
IRF3 mediated activation of type 1 IFN	E3 ubiquitin-protein ligase DTX4 Interferon regulatory factor 3 NACHT, LRR and PYD domains-containing protein 4 Serine/threonine-protein kinase TBK1 Z-DNA-binding protein 1	Q14653 Q96MN2 Q9H171 Q9UHD2 Q9Y2E6	C20orf183 DLM1 DTX4 IRF3 KIAA0937 NAK NALP4 NLRP4 PAN2 PYPAF4 RNF155 RNH2 TBK1 ZBP1	Homo sapiens (human)
Toll Like Receptor 9 (TLR9) Cascade	Early endosome antigen 1 Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphoinositide 3-kinase regulatory subunit 4 Rabenosyn-5 Toll-like receptor 9	Q15075 Q8NEB9 Q99570 Q9H1K0 Q9NR96	EEA1 PIK3C3 PIK3R4 RBSN TLR9 VPS15 VPS34 ZFYVE2 ZFYVE20	Homo sapiens (human)
Pyrophosphate hydrolysis	Inorganic pyrophosphatase 2, mitochondrial Inorganic pyrophosphatase Phospholysine phosphohistidine inorganic pyrophosphate phosphatase	Q15181 Q9H008 Q9H2U2	IOPPP LHPP PP PPA1 PPA2	Homo sapiens (human)
Cellular response to hypoxia	Endothelial PAS domain-containing protein 1 Hypoxia-inducible factor 1-alpha inhibitor Hypoxia-inducible factor 1-alpha	Q16665 Q99814 Q9NWT6	BHLHE73 BHLHE78 EPAS1 FIH1 HIF1A HIF1AN HIF2A MOP1 MOP2 PASD2 PASD8	Homo sapiens (human)
Defective CYP1B1 causes Glaucoma	Cytochrome P450 1B1	Q16678	CYP1B1	Homo sapiens (human)

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