GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **2051 - 2075** of **2090** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism
gilteritinib-resistant FLT3 mutants	Receptor-type tyrosine-protein kinase FLT3	P36888	CD135 FLK2 FLT3 STK1	Homo sapiens (human)
lestaurtinib-resistant FLT3 mutants	Receptor-type tyrosine-protein kinase FLT3	P36888	CD135 FLK2 FLT3 STK1	Homo sapiens (human)
linifanib-resistant FLT3 mutants	Receptor-type tyrosine-protein kinase FLT3	P36888	CD135 FLK2 FLT3 STK1	Homo sapiens (human)
lorlatinib-resistant ALK mutants	ALK tyrosine kinase receptor	Q9UM73	ALK	Homo sapiens (human)
mRNA 3'-end processing	ATP-dependent RNA helicase DDX39A Chromatin target of PRMT1 protein Cleavage and polyadenylation specificity factor subunit 1 Cleavage and polyadenylation specificity factor subunit 2 Cleavage and polyadenylation specificity factor subunit 3 Cleavage and polyadenylation specificity factor subunit 4 Cleavage and polyadenylation specificity factor subunit 5 Cleavage and polyadenylation specificity factor subunit 7 Cleavage stimulation factor subunit 1 Cleavage stimulation factor subunit 2 tau variant Cleavage stimulation factor subunit 2 Cleavage stimulation factor subunit 3 Eukaryotic initiation factor 4A-III Leucine zipper protein 4 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Poly(A) polymerase alpha Polyadenylate-binding protein 2 Polymerase delta-interacting protein 3 Polyribonucleotide 5'-hydroxyl-kinase Clp1 Pre-mRNA 3'-end-processing factor FIP1 Pre-mRNA cleavage complex 2 protein Pcf11 Pre-mRNA-processing factor 17 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 Pre-mRNA-splicing factor SLU7 Protein CASC3 Protein mago nashi homolog 2 Protein mago nashi homolog RNA-binding protein 8A RNA-binding protein with serine-rich domain 1 Regulator of nonsense transcripts 3B SAP domain-containing ribonucleoprotein Serine/arginine repetitive matrix protein 1 Serine/arginine-rich splicing factor 11 Serine/arginine-rich splicing factor 1 Serine/arginine-rich splicing factor 2 Serine/arginine-rich splicing factor 3 Serine/arginine-rich splicing factor 4 Serine/arginine-rich splicing factor 5 Serine/arginine-rich splicing factor 6 Serine/arginine-rich splicing factor 7 Serine/arginine-rich splicing factor 9 Spliceosome RNA helicase DDX39B Splicing factor U2AF 26 kDa subunit Splicing factor U2AF 35 kDa subunit Splicing factor U2AF 65 kDa subunit Symplekin THO complex subunit 1 THO complex subunit 2 THO complex subunit 3 THO complex subunit 4 THO complex subunit 5 homolog THO complex subunit 6 homolog THO complex subunit 7 homolog UAP56-interacting factor Zinc finger CCCH domain-containing protein 11A pre-mRNA 3' end processing protein WDR33	O00148 O15234 O43809 O60508 O75152 O94913 O95391 O95639 P26368 P33240 P38919 P51003 P52298 P61326 P82979 P84103 Q01081 Q01130 Q05048 Q05519 Q07955 Q08170 Q09161 Q10570 Q12996 Q13242 Q13243 Q13247 Q13769 Q13838 Q15287 Q16629 Q6I9Y2 Q6UN15 Q86U42 Q86V81 Q86W42 Q8IYB3 Q8N684 Q8NI27 Q8WU68 Q92620 Q92797 Q92989 Q96A72 Q96FV9 Q96J01 Q96QD9 Q9BY77 Q9BZI7 Q9C0J8 Q9H0L4 Q9P127 Q9P2I0 Q9UKF6 Q9Y3Y2 Q9Y5S9	ALY ALYREF ASF BAT1 BEF C1orf77 C22orf19 CASC3 CBP20 CBP80 CDC40 CFIM25 CHTOP CLP1 CPSF1 CPSF100 CPSF160 CPSF2 CPSF25 CPSF3 CPSF30 CPSF4 CPSF5 CPSF7 CPSF73 CSTF1 CSTF2 CSTF2T CSTF3 CXorf3 DDX38 DDX39 DDX39A DDX39B DDX48 DHX38 EHB3 EIF4A3 FIP1 FIP1L1 FOP FYTTD1 HCC1 HEAB HPR1 HRS KIAA0111 KIAA0224 KIAA0663 KIAA0689 KIAA0824 KIAA0983 KIAA1367 KIAA1649 LDC2 LUZP4 MAGOH MAGOH2 MAGOHA MAGOHB MLN51 NAR NCBP NCBP1 NCBP2 NEB1 NIF3L1BP1 NUDT21 PAB2 PABP2 PABPN1 PAP PAPOLA PCF11 PDIP46 POLDIP3 PRP16 PRP17 PRPF17 RBM8 RBM8A RENT3B RHE RNPS1 SARNP SF2 SF2P33 SFRS1 SFRS11 SFRS2 SFRS3 SFRS4 SFRS5 SFRS6 SFRS7 SFRS9 SLU7 SPK SRM160 SRP20 SRP30C SRP40 SRP55 SRP75 SRRM1 SRSF1 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF9 SYMPK THOC1 THOC2 THOC3 THOC4 THOC5 THOC6 THOC7 U2AF1 U2AF1-RS3 U2AF1L3 U2AF1L4 U2AF2 U2AF35 U2AF65 U2AFBP UAP56 UIF UPF3B UPF3X WDC146 WDR33 WDR58 ZC3H11A ZC3HDC11A	Homo sapiens (human)
mRNA Capping	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-dependent kinase 7 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Transcription elongation factor SPT5 mRNA cap guanine-N7 methyltransferase mRNA-capping enzyme	O00267 O15514 O43148 O60942 P13984 P18074 P19387 P19388 P19447 P24928 P30876 P32780 P35269 P36954 P50613 P51946 P51948 P52298 P52434 P52435 P53803 P61218 P62487 P62875 Q09161 Q13888 Q13889 Q6ZYL4 Q92759	BTF2 BTF2P44 C6orf175 CAK CAK1 CAP1A CAP35 CBP20 CBP80 CCNH CDK7 CDKN7 ERCC2 ERCC3 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 KIAA0398 MAT1 MNAT1 MO15 NCBP NCBP1 NCBP2 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RNF66 RNGTT RNMT RPB7 SPT5 SPT5H STK1 SUPT5H TTDA XPB XPBC XPD XPDC	Homo sapiens (human)
mRNA Editing: C to U Conversion	APOBEC1 complementation factor C->U-editing enzyme APOBEC-1 C->U-editing enzyme APOBEC-2 DNA dC->dU-editing enzyme APOBEC-3A DNA dC->dU-editing enzyme APOBEC-3B DNA dC->dU-editing enzyme APOBEC-3C DNA dC->dU-editing enzyme APOBEC-3H Putative C->U-editing enzyme APOBEC-4	P31941 P41238 Q6NTF7 Q8WW27 Q9NQ94 Q9NRW3 Q9UH17 Q9Y235	A1CF ACF APOBEC1 APOBEC1L APOBEC2 APOBEC3A APOBEC3B APOBEC3C APOBEC3H APOBEC4 ASP C1orf169 PBI	Homo sapiens (human)
mRNA decay by 3' to 5' exoribonuclease	7-methylguanosine phosphate-specific 5'-nucleotidase Exosome complex component CSL4 Exosome complex component MTR3 Exosome complex component RRP40 Exosome complex component RRP41 Exosome complex component RRP42 Exosome complex component RRP43 Exosome complex component RRP45 Exosome complex component RRP46 Exosome complex component RRP4 Exosome complex exonuclease RRP44 HBS1-like protein Superkiller complex protein 2 Superkiller complex protein 3 Superkiller complex protein 8 m7GpppX diphosphatase	Q06265 Q13868 Q15024 Q15477 Q5RKV6 Q6PGP7 Q969T7 Q96B26 Q96C86 Q9GZS3 Q9NPD3 Q9NQT4 Q9NQT5 Q9Y2L1 Q9Y3B2 Q9Y450	CML28 CSL4 DCPS DCS1 DDX13 DIS3 EXOSC1 EXOSC2 EXOSC3 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 HBS1 HBS1L HINT5 KIAA0116 KIAA0372 KIAA1008 KIAA1038 MTR3 NT5C3B NT5C3L OIP2 PMSCL1 RRP4 RRP40 RRP41 RRP42 RRP43 RRP44 RRP46 SKI2W SKI6 SKIC2 SKIC3 SKIC8 SKIV2 SKIV2L TTC37 W WDR61	Homo sapiens (human)
mRNA decay by 5' to 3' exoribonuclease	5'-3' exoribonuclease 1 Enhancer of mRNA-decapping protein 3 Enhancer of mRNA-decapping protein 4 Probable ATP-dependent RNA helicase DDX6 Protein PAT1 homolog 1 U6 snRNA-associated Sm-like protein LSm1 U6 snRNA-associated Sm-like protein LSm2 U6 snRNA-associated Sm-like protein LSm3 U6 snRNA-associated Sm-like protein LSm4 U6 snRNA-associated Sm-like protein LSm5 U6 snRNA-associated Sm-like protein LSm6 U6 snRNA-associated Sm-like protein LSm7 m7GpppN-mRNA hydrolase mRNA-decapping enzyme 1A mRNA-decapping enzyme 1B	O15116 P26196 P62310 P62312 Q6P2E9 Q86TB9 Q8IU60 Q8IZD4 Q8IZH2 Q96F86 Q9NPI6 Q9UK45 Q9Y333 Q9Y4Y9 Q9Y4Z0	C6orf28 CASM DCP1A DCP1B DCP2 DDX6 EDC3 EDC4 G7B HEDLS HLR2 LSM1 LSM16 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 NUDT20 PATL1 RCK SEP1 SMIF XRN1 YJDC YJEFN2	Homo sapiens (human)
mTORC1-mediated signalling	14-3-3 protein beta/alpha Eukaryotic elongation factor 2 kinase Eukaryotic translation initiation factor 4 gamma 1 Eukaryotic translation initiation factor 4B Eukaryotic translation initiation factor 4E-binding protein 1 Eukaryotic translation initiation factor 4E GTP-binding protein Rheb Neutral amino acid transporter 9 Peptidyl-prolyl cis-trans isomerase FKBP1A Proline-rich AKT1 substrate 1 Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR Ribosomal protein S6 kinase beta-1 Serine/threonine-protein kinase mTOR Small ribosomal subunit protein eS6 Target of rapamycin complex subunit LST8	O00418 O43504 P06730 P23443 P23588 P31946 P42345 P62753 P62942 Q04637 Q0VGL1 Q13541 Q15382 Q5VZM2 Q6IAA8 Q7L523 Q8N122 Q8NBW4 Q96B36 Q9BVC4 Q9HB90 Q9NQL2 Q9UHA4 Q9Y2Q5	AKT1S1 C11orf59 C7orf59 EEF2K EIF4B EIF4E EIF4EBP1 EIF4EL1 EIF4F EIF4G EIF4G1 EIF4GI FKBP1 FKBP12 FKBP1A FRAP FRAP1 FRAP2 GBL HBXIP KIAA1303 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LST8 MAP2K1IP1 MAPBPIP MAPKSP1 MLST8 MTOR PDRO PRAS40 RAFT1 RAPT1 RAPTOR RHEB RHEB2 ROBLD3 RPS6 RPS6KB1 RPTOR RRAGA RRAGB RRAGC RRAGD SLC38A9 STK14A URLC11 XIP YWHAB	Homo sapiens (human)
midostaurin-resistant FLT3 mutants	Receptor-type tyrosine-protein kinase FLT3	P36888	CD135 FLK2 FLT3 STK1	Homo sapiens (human)
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids	2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial Enoyl-CoA delta isomerase 1, mitochondrial Long-chain specific acyl-CoA dehydrogenase, mitochondrial Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P11310 P28330 P40939 P42126 P55084 Q16698	ACADL ACADM DCI DECR DECR1 ECI1 HADH HADHA HADHB SDR18C1	Homo sapiens (human)
p130Cas linkage to MAPK signaling for integrins	Adapter molecule crk Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Breast cancer anti-estrogen resistance protein 1 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin Focal adhesion kinase 1 Integrin alpha-IIb Integrin beta-3 Proto-oncogene tyrosine-protein kinase Src Ras-related protein Rap-1A Ras-related protein Rap-1b Talin-1 von Willebrand factor	P02671 P02675 P02679 P02751 P04275 P05106 P08514 P12931 P46108 P56945 P61224 P62834 Q05397 Q7Z5R6 Q9Y490	APBB1IP BCAR1 CAS CASS1 CRK CRKAS F8VWF FAK FAK1 FGA FGB FGG FN FN1 GP2B GP3A ITGA2B ITGAB ITGB3 KIAA1027 KREV1 PREL1 PTK2 RAP1A RAP1B RARP1 RIAM SRC SRC1 TLN TLN1 VWF	Homo sapiens (human)
p38MAPK events	GTPase HRas GTPase NRas MAP kinase-activated protein kinase 2 MAP kinase-activated protein kinase 3 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 12 Mitogen-activated protein kinase 13 Mitogen-activated protein kinase 14 Ral guanine nucleotide dissociation stimulator Ras-related protein Ral-A Ras-related protein Ral-B	O15264 P01111 P01112 P11233 P11234 P49137 P53778 Q12967 Q15759 Q16539 Q16644	CSBP CSBP1 CSBP2 CSPB1 ERK6 HRAS HRAS1 KIAA1308 MAPK11 MAPK12 MAPK13 MAPK14 MAPKAPK2 MAPKAPK3 MXI2 NRAS PRKM11 PRKM13 RAL RALA RALB RALGDS RGF SAPK2 SAPK2A SAPK2B SAPK3 SAPK4	Homo sapiens (human)
p53-Dependent G1 DNA Damage Response	Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B G1/S-specific cyclin-E1 G1/S-specific cyclin-E2	O96020 P20248 P24864 P24941 P38936 P46527 P78396	CAP20 CCN1 CCNA CCNA1 CCNA2 CCNE CCNE1 CCNE2 CDK2 CDKN1 CDKN1A CDKN1B CDKN2 CIP1 KIP1 MDA6 PIC1 SDI1 WAF1 p27	Homo sapiens (human)
p75NTR negatively regulates cell cycle via SC1	Beta-nerve growth factor Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 PR domain zinc finger protein 4 Tumor necrosis factor receptor superfamily member 16	O15379 P01138 P08138 Q13547 Q92769 Q9UKN5	HDAC1 HDAC2 HDAC3 NGF NGFB NGFR PFM1 PRDM4 RPD3L1 TNFRSF16	Homo sapiens (human)
p75NTR recruits signalling complexes	Beta-nerve growth factor Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 Myeloid differentiation primary response protein MyD88 Polyubiquitin-B Polyubiquitin-C Protein kinase C iota type Receptor-interacting serine/threonine-protein kinase 2 Sequestosome-1 TNF receptor-associated factor 6 Tumor necrosis factor receptor superfamily member 16 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14920 O43353 P01138 P08138 P0CG47 P0CG48 P41743 P51617 P62979 P62987 Q13501 Q99836 Q9Y4K3	CARDIAK DXS1179E IKBKB IKKB IRAK IRAK1 MYD88 NGF NGFB NGFR ORCA OSIL PRKCI RICK RIP2 RIPK2 RNF85 RPS27A SQSTM1 TNFRSF16 TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
pexidartinib-resistant FLT3 mutants	Receptor-type tyrosine-protein kinase FLT3	P36888	CD135 FLK2 FLT3 STK1	Homo sapiens (human)
phospho-PLA2 pathway	Cytosolic phospholipase A2 Mitogen-activated protein kinase 1	P28482 P47712	CPLA2 ERK2 MAPK1 PLA2G4 PLA2G4A PRKM1 PRKM2	Homo sapiens (human)
ponatinib-resistant FLT3 mutants	Receptor-type tyrosine-protein kinase FLT3	P36888	CD135 FLK2 FLT3 STK1	Homo sapiens (human)
pre-mRNA splicing	116 kDa U5 small nuclear ribonucleoprotein component 17S U2 SnRNP complex component HTATSF1 ATP-dependent RNA helicase A ATP-dependent RNA helicase DDX42 ATP-dependent RNA helicase DHX15 ATP-dependent RNA helicase DHX8 Apoptotic chromatin condensation inducer in the nucleus BUD13 homolog Beta-catenin-like protein 1 CWF19-like protein 2 Calcium homeostasis endoplasmic reticulum protein Cell division cycle 5-like protein Cell division cycle and apoptosis regulator protein 1 Coiled-coil domain-containing protein 12 Crooked neck-like protein 1 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 DnaJ homolog subfamily C member 8 E3 ubiquitin-protein ligase RNF113A Eukaryotic initiation factor 4A-III Exosome RNA helicase MTR4 G patch domain-containing protein 1 G-patch domain and KOW motifs-containing protein General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Heat shock cognate 71 kDa protein Heterogeneous nuclear ribonucleoprotein A1 Heterogeneous nuclear ribonucleoprotein A3 Heterogeneous nuclear ribonucleoprotein D0 Heterogeneous nuclear ribonucleoprotein F Heterogeneous nuclear ribonucleoprotein H2 Heterogeneous nuclear ribonucleoprotein H Heterogeneous nuclear ribonucleoprotein K Heterogeneous nuclear ribonucleoprotein L Heterogeneous nuclear ribonucleoprotein M Heterogeneous nuclear ribonucleoprotein R Heterogeneous nuclear ribonucleoprotein U Heterogeneous nuclear ribonucleoproteins A2/B1 Heterogeneous nuclear ribonucleoproteins C1/C2 Histone deacetylase complex subunit SAP18 Intron Large complex component GCFC2 Leukocyte receptor cluster member 1 Luc7-like protein 3 Microfibrillar-associated protein 1 NF-kappa-B-activating protein NHP2-like protein 1 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Nuclear inhibitor of protein phosphatase 1 Nuclear speckle splicing regulatory protein 1 PHD finger-like domain-containing protein 5A PRKR-interacting protein 1 Peptidyl-prolyl cis-trans isomerase E Peptidyl-prolyl cis-trans isomerase G Peptidyl-prolyl cis-trans isomerase H Peptidyl-prolyl cis-trans isomerase-like 1 Peptidyl-prolyl cis-trans isomerase-like 3 Peptidyl-prolyl cis-trans isomerase-like 4 Peptidylprolyl isomerase domain and WD repeat-containing protein 1 Pinin Pleiotropic regulator 1 Poly(U)-binding-splicing factor PUF60 Poly(rC)-binding protein 1 Poly(rC)-binding protein 2 Polyglutamine-binding protein 1 Polypyrimidine tract-binding protein 1 Pre-mRNA-processing factor 17 Pre-mRNA-processing factor 19 Pre-mRNA-processing factor 40 homolog A Pre-mRNA-processing factor 6 Pre-mRNA-processing-splicing factor 8 Pre-mRNA-splicing factor 18 Pre-mRNA-splicing factor 38A Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 Pre-mRNA-splicing factor CWC22 homolog Pre-mRNA-splicing factor CWC25 homolog Pre-mRNA-splicing factor ISY1 homolog Pre-mRNA-splicing factor RBM22 Pre-mRNA-splicing factor SLU7 Pre-mRNA-splicing factor SPF27 Pre-mRNA-splicing factor SYF1 Pre-mRNA-splicing factor SYF2 Probable ATP-dependent RNA helicase DDX23 Probable ATP-dependent RNA helicase DDX41 Probable ATP-dependent RNA helicase DDX46 Probable ATP-dependent RNA helicase DDX5 Probable ATP-dependent RNA helicase DHX35 Proline-rich protein PRCC Protein BUD31 homolog Protein CASC3 Protein FAM32A Protein FAM50A Protein Red Protein mago nashi homolog 2 Protein mago nashi homolog RING-type E3 ubiquitin-protein ligase PPIL2 RNA helicase aquarius RNA-binding motif protein, X chromosome RNA-binding motif protein, X-linked 2 RNA-binding protein 10 RNA-binding protein 25 RNA-binding protein 39 RNA-binding protein 42 RNA-binding protein 5 RNA-binding protein 7 RNA-binding protein 8A RNA-binding protein FUS RNA-binding protein with serine-rich domain 1 Regulator of nonsense transcripts 3B SNW domain-containing protein 1 STING ER exit protein SURP and G-patch domain-containing protein 1 Serine/arginine repetitive matrix protein 1 Serine/arginine repetitive matrix protein 2 Serine/arginine-rich splicing factor 10 Serine/arginine-rich splicing factor 11 Serine/arginine-rich splicing factor 12 Serine/arginine-rich splicing factor 1 Serine/arginine-rich splicing factor 2 Serine/arginine-rich splicing factor 3 Serine/arginine-rich splicing factor 4 Serine/arginine-rich splicing factor 5 Serine/arginine-rich splicing factor 6 Serine/arginine-rich splicing factor 7 Serine/arginine-rich splicing factor 8 Serine/arginine-rich splicing factor 9 Serine/threonine-protein kinase PRP4 homolog Serrate RNA effector molecule homolog Smad nuclear-interacting protein 1 Small nuclear ribonucleoprotein E Small nuclear ribonucleoprotein F Small nuclear ribonucleoprotein G Small nuclear ribonucleoprotein Sm D1 Small nuclear ribonucleoprotein Sm D2 Small nuclear ribonucleoprotein Sm D3 Small nuclear ribonucleoprotein-associated protein N Small nuclear ribonucleoprotein-associated proteins B and B' Spliceosome RNA helicase DDX39B Spliceosome-associated protein CWC15 homolog Spliceosome-associated protein CWC27 homolog Splicing factor 1 Splicing factor 3A subunit 1 Splicing factor 3A subunit 2 Splicing factor 3A subunit 3 Splicing factor 3B subunit 1 Splicing factor 3B subunit 2 Splicing factor 3B subunit 3 Splicing factor 3B subunit 4 Splicing factor 3B subunit 5 Splicing factor 3B subunit 6 Splicing factor 45 Splicing factor C9orf78 Splicing factor Cactin Splicing factor U2AF 26 kDa subunit Splicing factor U2AF 35 kDa subunit Splicing factor U2AF 65 kDa subunit Splicing factor YJU2 Splicing regulator SDE2 Survival of motor neuron-related-splicing factor 30 THO complex subunit 4 Thioredoxin-like protein 4A Transcription elongation regulator 1 Transformer-2 protein homolog beta Tuftelin-interacting protein 11 U1 small nuclear ribonucleoprotein 70 kDa U1 small nuclear ribonucleoprotein A U1 small nuclear ribonucleoprotein C U2 small nuclear ribonucleoprotein A' U2 small nuclear ribonucleoprotein B'' U2 snRNP-associated SURP motif-containing protein U4/U6 small nuclear ribonucleoprotein Prp31 U4/U6 small nuclear ribonucleoprotein Prp3 U4/U6 small nuclear ribonucleoprotein Prp4 U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein U4/U6.U5 tri-snRNP-associated protein 1 U5 small nuclear ribonucleoprotein 200 kDa helicase U5 small nuclear ribonucleoprotein 40 kDa protein U6 snRNA-associated Sm-like protein LSm2 U6 snRNA-associated Sm-like protein LSm3 U6 snRNA-associated Sm-like protein LSm4 U6 snRNA-associated Sm-like protein LSm5 U6 snRNA-associated Sm-like protein LSm6 U6 snRNA-associated Sm-like protein LSm7 U6 snRNA-associated Sm-like protein LSm8 Ubiquitin carboxyl-terminal hydrolase 39 Ubiquitin-like protein 5 WD repeat-containing protein 70 WD40 repeat-containing protein SMU1 WW domain-binding protein 11 WW domain-binding protein 4 Y-box-binding protein 1 Zinc finger matrin-type protein 2 Zinc finger protein 830	O00422 O14776 O15042 O15234 O15514 O15541 O43143 O43172 O43290 O43390 O43395 O43447 O43660 O43719 O60231 O60306 O60508 O60828 O75400 O75494 O75533 O75554 O75643 O75934 O75937 O75940 O94906 O95232 O95391 O95777 O95926 P07910 P08579 P08621 P09012 P09234 P09651 P09661 P11142 P13984 P14678 P14866 P16383 P17844 P19387 P19388 P22626 P24928 P26368 P26599 P30876 P31943 P35269 P35637 P36954 P38159 P38919 P41223 P42285 P49756 P51991 P52272 P52298 P52434 P52435 P52597 P52756 P53803 P55081 P55769 P55795 P61218 P61326 P61978 P62304 P62306 P62308 P62310 P62312 P62314 P62316 P62318 P62487 P62875 P62995 P63162 P67809 P83876 P84103 P98175 Q00839 Q01081 Q01130 Q05519 Q07955 Q08170 Q08211 Q09161 Q12874 Q12972 Q13123 Q13242 Q13243 Q13247 Q13356 Q13427 Q13435 Q13523 Q13573 Q13838 Q14103 Q14320 Q14498 Q14562 Q15029 Q15287 Q15365 Q15366 Q15393 Q15427 Q15428 Q15459 Q15637 Q16629 Q2TAY7 Q2TBE0 Q53GS9 Q6IQ49 Q6P2Q9 Q6UX04 Q7L014 Q7RTV0 Q86V81 Q86XP3 Q8IWX8 Q8IWZ8 Q8IX12 Q8IYB3 Q8N5F7 Q8NAV1 Q8TAD8 Q8WU68 Q8WUA2 Q8WUD4 Q8WUQ7 Q8WVK2 Q8WWY3 Q8WXF0 Q8WYA6 Q92620 Q92733 Q92917 Q96A72 Q96BP3 Q96BZ8 Q96DI7 Q96I25 Q96NB3 Q96NC0 Q99459 Q99633 Q9BRD0 Q9BRL6 Q9BRR8 Q9BTD8 Q9BUQ8 Q9BW85 Q9BWJ5 Q9BXP5 Q9BZI7 Q9BZJ0 Q9BZL1 Q9H0G5 Q9H2H8 Q9H307 Q9H5V9 Q9H5Z1 Q9H875 Q9HCG8 Q9HCS7 Q9NW64 Q9NW82 Q9NXE8 Q9NZ63 Q9P013 Q9UBB9 Q9UHX1 Q9UJV9 Q9UK45 Q9UKV3 Q9ULR0 Q9UMS4 Q9UNP9 Q9UQ35 Q9Y2W2 Q9Y333 Q9Y388 Q9Y3B4 Q9Y3C6 Q9Y421 Q9Y4Y9 Q9Y4Z0 Q9Y580 Q9Y5S9	ABS ACIN1 ACINUS ALY ALYREF AQR ARD1 ARS2 ASCC3L1 ASF ASR2 AUF1 BAT1 BCAS2 BEF BRR2 BUD13 BUD31 C11orf5 C19orf29 C1orf199 C1orf55 C20orf14 C20orf15 C20orf33 C2orf3 C6orf28 C9orf78 CA150 CACTIN CARP1 CASC3 CBP20 CBP80 CBPIN CCAR1 CCDC12 CCDC16 CCDC49 CCDC55 CCDC94 CDC40 CDC5L CHERP COD CREAP1 CRN CRNKL1 CROP CTNNBL1 CWC15 CWC22 CWC25 CWC27 CWF19L2 CXorf56 CYP20 CYP33 CYPH CYPL1 DAM1 DAN26 DBP1 DBP2 DDX15 DDX16 DDX23 DDX35 DDX38 DDX39B DDX41 DDX42 DDX46 DDX48 DDX5 DDX8 DDX9 DHX15 DHX16 DHX35 DHX38 DHX8 DHX9 DIM1 DIS DNAJC8 DOB1 DRS DXS8237E DXS9928E ECGP EDG2 EFTUD2 EHB3 EIF4A3 FAM32A FAM50A FBP11 FBP21 FIR FLAF1 FNBP21 FNBP3 FTP3 FUS FUSIP1 FUSIP2 G17P1 G7B GCF GCFC2 GCIPIP GPATC1 GPATC5 GPATC9 GPATCH1 GPATCH5 GPATCH9 GPKOW GTF2F1 GTF2F2 HCA59 HCC1 HCERN3 HCNP HELIC2 HELR HIP10 HLR1 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPL HNRNPM HNRNPR HNRNPU HNRPA1 HNRPA2B1 HNRPA3 HNRPC HNRPD HNRPF HNRPG HNRPH HNRPH1 HNRPH2 HNRPK HNRPL HNRPM HNRPR HNRPU HPRP18 HPRP3 HRS HSC70 HSP73 HSPA10 HSPA8 HTATSF1 HXC26 HYPA IK ISY1 KIAA0017 KIAA0031 KIAA0052 KIAA0073 KIAA0111 KIAA0122 KIAA0224 KIAA0324 KIAA0332 KIAA0432 KIAA0536 KIAA0560 KIAA0577 KIAA0670 KIAA0788 KIAA0801 KIAA1160 KIAA1177 KIAA1604 LDC2 LENG1 LKP LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 LSM8 LUC7L3 MAGOH MAGOH2 MAGOHA MAGOHB MEMA MFAP1 MLN51 MTR4 MTREX NAGR1 NCBP NCBP1 NCBP2 NCM NDH2 NHP2L1 NIPP1 NKAP NMP200 NPW38 NPWBP NSEP1 NSRP1 NSRP70 O48 OTAG12 PBSCF PBSCG PCBP1 PCBP2 PCDC5RP PHF5A PLRG1 PNN POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PPIE PPIG PPIH PPIL1 PPIL2 PPIL3 PPIL4 PPP1R8 PPWD1 PQBP1 PRCC PRKRIP1 PRP16 PRP17 PRP19 PRP2 PRP3 PRP31 PRP4 PRP4B PRP4H PRP4K PRP8BP PRPC8 PRPF17 PRPF18 PRPF19 PRPF3 PRPF31 PRPF38A PRPF4 PRPF40A PRPF4K PRPF6 PRPF8 PTB PTBP1 PUF60 RAP30 RAP74 RBM10 RBM17 RBM22 RBM25 RBM39 RBM42 RBM5 RBM7 RBM8 RBM8A RBMX RBMX2 RBMXP1 RED RENT3B RER RNF113 RNF113A RNPC2 RNPC7 RNPS1 RNPU1Z ROBPI RPB7 RPU1 SAFA SAP114 SAP130 SAP14 SAP145 SAP155 SAP18 SAP49 SAP61 SAP62 SART1 SCAF6 SDCCAG10 SDE2 SF1 SF2 SF2P33 SF3A1 SF3A2 SF3A3 SF3B1 SF3B10 SF3B14 SF3B14A SF3B2 SF3B3 SF3B4 SF3B5 SF3B6 SF4 SFP38 SFRS1 SFRS10 SFRS11 SFRS13A SFRS13B SFRS19 SFRS2 SFRS2B SFRS3 SFRS4 SFRS5 SFRS6 SFRS7 SFRS9 SIAHBP1 SIPP1 SKIIP SKIP SKIV2L2 SLU7 SMN SMNDC1 SMNR SMU1 SNEV SNIP1 SNP70 SNRNP200 SNRNP27 SNRNP40 SNRNP70 SNRP116 SNRP70 SNRPA SNRPA1 SNRPB SNRPB1 SNRPB2 SNRPC SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNRPN SNU13 SNW1 SPF30 SPF31 SPF45 SR140 SRL300 SRM160 SRM300 SRP20 SRP30C SRP40 SRP46 SRP55 SRP75 SRRM1 SRRM2 SRRP35 SRRT SRSF1 SRSF10 SRSF11 SRSF12 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SRSF9 STEEP1 STIP SUGP1 SYF1 SYF2 T54 TAF2S TASR TCERG1 TCF9 TFIP11 THOC4 TLS TPRC TRA2B TXNL4 TXNL4A U1AP1 U21.1 U2AF1 U2AF1-RS3 U2AF1L3 U2AF1L4 U2AF2 U2AF35 U2AF65 U2AFBP U2SURP UAP56 UBL5 UPF3B UPF3X USP39 WBP11 WBP4 WDR57 WDR70 XAB2 XAP5 YB1 YBX1 YJU2 ZC3H16 ZFM1 ZMAT2 ZNF162 ZNF183 ZNF830	Homo sapiens (human)
quizartinib-resistant FLT3 mutants	Receptor-type tyrosine-protein kinase FLT3	P36888	CD135 FLK2 FLT3 STK1	Homo sapiens (human)
rRNA modification in the mitochondrion	5-methylcytosine rRNA methyltransferase NSUN4 Dimethyladenosine transferase 1, mitochondrial Transcription termination factor 4, mitochondrial rRNA methyltransferase 1, mitochondrial rRNA methyltransferase 2, mitochondrial rRNA methyltransferase 3, mitochondrial	Q6IN84 Q7Z6M4 Q8WVM0 Q96CB9 Q9HC36 Q9UI43	FJH1 FTSJ2 MRM1 MRM2 MRM3 MTERF4 MTERFD2 NSUN4 RNMTL1 TFB1M	Homo sapiens (human)
rRNA modification in the nucleus and cytosol	18S rRNA aminocarboxypropyltransferase DDB1- and CUL4-associated factor 13 H/ACA ribonucleoprotein complex subunit 1 H/ACA ribonucleoprotein complex subunit 2 H/ACA ribonucleoprotein complex subunit 3 H/ACA ribonucleoprotein complex subunit DKC1 HEAT repeat-containing protein 1 KRR1 small subunit processome component homolog Multifunctional methyltransferase subunit TRM112-like protein NHP2-like protein 1 Nucleolar complex protein 4 homolog Nucleolar protein 11 Nucleolar protein 14 Nucleolar protein 56 Nucleolar protein 58 Nucleolar protein 6 Periodic tryptophan protein 2 homolog Probable 18S rRNA (guanine-N(7))-methyltransferase Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase Probable ATP-dependent RNA helicase DDX47 Probable ATP-dependent RNA helicase DDX49 Probable ATP-dependent RNA helicase DDX52 Probable ATP-dependent RNA helicase DHX37 Probable U3 small nucleolar RNA-associated protein 11 Probable dimethyladenosine transferase Protein RRP5 homolog RNA 3'-terminal phosphate cyclase-like protein RNA cytidine acetyltransferase RNA-binding protein PNO1 Ribosomal RNA processing protein 36 homolog Ribosomal RNA small subunit methyltransferase NEP1 Ribosomal RNA-processing protein 7 homolog A Ribosome biogenesis protein BMS1 homolog Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small subunit processome component 20 homolog Something about silencing protein 10 THUMP domain-containing protein 1 Transducin beta-like protein 3 U3 small nucleolar RNA-associated protein 14 homolog A U3 small nucleolar RNA-associated protein 14 homolog C U3 small nucleolar RNA-associated protein 15 homolog U3 small nucleolar RNA-associated protein 18 homolog U3 small nucleolar RNA-associated protein 25 homolog U3 small nucleolar RNA-associated protein 4 homolog U3 small nucleolar RNA-associated protein 6 homolog U3 small nucleolar RNA-interacting protein 2 U3 small nucleolar ribonucleoprotein protein IMP3 U3 small nucleolar ribonucleoprotein protein IMP4 U3 small nucleolar ribonucleoprotein protein MPP10 WD repeat-containing protein 36 WD repeat-containing protein 3 WD repeat-containing protein 43 WD repeat-containing protein 46 WD repeat-containing protein 75 rRNA 2'-O-methyltransferase fibrillarin rRNA-processing protein FCF1 homolog	O00566 O00567 O15213 O43709 O43818 O60832 O75691 P15880 P22087 P46087 P46781 P55769 P62081 P62263 P62753 P78316 Q12788 Q13601 Q14690 Q14692 Q15061 Q15269 Q5TAP6 Q68CQ4 Q8IWA0 Q8IY37 Q8NI36 Q8TED0 Q92979 Q969X6 Q96EU6 Q96G21 Q9BVI4 Q9BVJ6 Q9H0A0 Q9H0S4 Q9H583 Q9H6R4 Q9H8H0 Q9NPE3 Q9NQZ2 Q9NRX1 Q9NV06 Q9NV31 Q9NX24 Q9NXG2 Q9NY12 Q9NYH9 Q9UI30 Q9UJK0 Q9UNQ2 Q9UNX4 Q9Y2P8 Q9Y2R4 Q9Y2X3 Q9Y324 Q9Y3A2 Q9Y3A4 Q9Y5J1 Q9Y6V7	ALP BAP28 BING4 BMS1 BMS1L BUD23 BXDC4 C14orf111 C15orf12 C16orf42 C17orf40 C1orf107 C2F C4orf9 C6orf11 C6orf153 CIRH1A CRLZ1 DCAF13 DDX37 DDX47 DDX49 DDX52 DEF DHX37 DIEXF DIMT1 DIMT1L DKC1 DRIM EMG1 FBL FCF1 FIB1 FLRN GAR1 HCA66 HEATR1 HRB2 IMP3 IMP4 KIAA0007 KIAA0185 KIAA0187 KIAA0266 KIAA1517 KIAA1709 KIAA1988 KRR1 MERM1 MHAT MPHOSPH10 MPP10 MRPS4 NAT10 NHP2 NHP2L1 NOC4L NOL1 NOL11 NOL14 NOL5 NOL5A NOL6 NOLA1 NOLA2 NOLA3 NOLA4 NOP10 NOP14 NOP2 NOP5 NOP56 NOP58 NSUN1 PDCD11 PNO1 PWP2 PWP2H RCL1 RNAC RNU3IP2 ROK1 RPC2 RPCL1 RPS14 RPS2 RPS4 RPS6 RPS7 RPS9 RRP36 RRP7A RRP9 RTC2 SAS10 SAZD SDCCAG16 SNU13 TBL3 THUMPD1 TRMT112 TSR3 U355K UND313L UTP10 UTP11 UTP11L UTP14A UTP14C UTP15 UTP17 UTP18 UTP20 UTP25 UTP3 UTP4 UTP5 UTP6 WBSCR22 WDR3 WDR36 WDR43 WDR46 WDR50 WDR75 WDSOF1 cPERP-E	Homo sapiens (human)
rRNA processing in the mitochondrion	3-hydroxyacyl-CoA dehydrogenase type-2 Mitochondrial ribonuclease P catalytic subunit Zinc phosphodiesterase ELAC protein 2 tRNA methyltransferase 10 homolog C	O15091 Q7L0Y3 Q99714 Q9BQ52	ELAC2 ERAB HADH2 HPC2 HSD17B10 KIAA0391 MRPP1 MRPP2 MRPP3 PRORP RG9MTD1 SCHAD SDR5C1 TRMT10C XH98G2	Homo sapiens (human)

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