GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **426 - 450** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
RUNX3 regulates WNT signaling	Catenin beta-1 Lymphoid enhancer-binding factor 1 Runt-related transcription factor Transcription factor 7 like 1 Transcription factor 7 like 2 Transcription factor 7	A0A0G2K7T0 A0A8I5ZLY3 A0A8I5ZT78 A0A8I6A9A2 Q9QXN1 Q9WU82	Catnb Ctnnb1 Lef1 Runx3 Tcf7 Tcf7l1 Tcf7l2	Rattus norvegicus (Norway rat)
Sphingolipid catabolism	Aldehyde dehydrogenase family 3 member A2 Aldehyde dehydrogenase family 3 member B1 Aldehyde dehydrogenase Alkaline ceramidase Alkaline ceramidase Alkaline ceramidase Phospholipid phosphatase 1 Phospholipid phosphatase 2 Phospholipid phosphatase 3 Sphingosine-1-phosphate lyase 1 Sphingosine-1-phosphate phosphatase 1 Sphingosine-1-phosphate phosphatase 2	A0A8I6ADP7 A0A8I6AGX4 A0A8I6AKN2 D3ZNW4 M0R603 O08564 P30839 P97544 Q5XI42 Q8CHN6 Q8K593 Q99P55	Acer1 Acer2 Acer3 Aldh3a2 Aldh3b1 Aldh3b2 Aldh4 Lpp1 Lpp2 Lpp3 Plpp1 Plpp2 Plpp3 Ppap2a Ppap2b Ppap2c Sgpl1 Sgpp1 Sgpp2 Spl	Rattus norvegicus (Norway rat)
Transcriptional activation of mitochondrial biogenesis	Cytochrome c domain-containing protein Cytochrome c, somatic GA binding protein transcription factor subunit alpha GA binding protein transcription factor subunit beta 1 Glutamate dehydrogenase 1, mitochondrial Isocitrate dehydrogenase [NADP], mitochondrial NAD-dependent protein deacylase sirtuin-5, mitochondrial NAD-dependent protein lipoamidase sirtuin-4, mitochondrial Propionate--CoA ligase Similar to Cytochrome c, somatic Sirtuin 3 Superoxide dismutase [Mn], mitochondrial	A0A0G2K6D8 A0A8I5XWT5 A0A8I5ZWD2 A0A8I6GJ11 D3ZXV2 D4A5L9 D4ACQ9 P07895 P10860 P56574 P62898 Q68FX9	AC128290.1 Acss2 Cycs Cycsl2 Cycsl3 Gabpa Gabpb1 Glud Glud1 Idh2 LOC690675 RGD1562558 SIRT4 Sirt3 Sirt4 Sirt5 Sod2	Rattus norvegicus (Norway rat)
Regulation of lipid metabolism by PPARalpha	DNA helicase Fatty acid-binding protein, liver Histone deacetylase 3 Histone lysine acetyltransferase CREBBP Histone-arginine methyltransferase CARM1 Mediator of RNA polymerase II transcription subunit 1 Nuclear receptor co-repressor 2 Nuclear receptor coactivator 2 Nuclear receptor coactivator Peroxisome proliferator-activated receptor alpha Retinoic acid receptor RXR-alpha SIN3 transcription regulator family member A SIN3 transcription regulator family member B SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 TBL1X/Y related 1 Transducin (beta)-like 1 X-linked Trimethylguanosine synthase	A0A096MJV7 A0A0G2JU91 A0A0G2JY80 A0A8I5ZQQ2 A0A8I6AC46 A0A8I6APA0 A0A8I6G8L9 D3ZBP2 D3ZNF4 P02692 P37230 P85107 Q05343 Q4AE70 Q6JHU9 Q6P6W3 Q9WUI9	Carm1 Cbp Chd9 Crebbp Fabp1 Hdac3 Med1 Ncoa1 Ncoa2 Ncoa6ip Ncor2 Nr1c1 Nr2b1 Pimt Ppar Ppara Prmt4 Rxra Sin3a Sin3b Smarcd3 Tbl1x Tbl1xr1 Tgs1 Tif2	Rattus norvegicus (Norway rat)
RHOG GTPase cycle	10 kDa heat shock protein, mitochondrial ADP-ribosylation factor GTPase-activating protein 3 Ankyrin repeat and LEM domain-containing protein 2 Caveolin-1 Cdc42 effector protein 1 Cell division control protein 42 homolog Cell surface glycoprotein MUC18 Cytoplasmic FMR1-interacting protein DEP domain containing 1B Dedicator of cyto-kinesis 3 Dedicator of cytokinesis 2 Dedicator of cytokinesis 4 Dedicator of cytokinesis 5 Delta(14)-sterol reductase LBR Desmoglein 2 Emerin Engulfment and cell motility 2 Extended synaptotagmin-1 Granule associated Rac and RHOG effector 1 Guanine nucleotide exchange factor DBS IQ motif containing GTPase activating protein 2 Integrin beta-1 Intersectin-1 Kalirin Kinectin 1 LOC687105 protein MAGUK p55 subfamily member 7 MCF.2 cell line derived transforming sequence Membrane-associated progesterone receptor component 2 Mitochondrial proton/calcium exchanger protein Mitogen-activated protein kinase kinase kinase 11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Phospholipase D1 Pleckstrin homology and RhoGEF domain containing G3 Protein ERGIC-53 Protein diaphanous homolog 3 Proto-oncogene vav RNA binding motif protein 39 Ragulator complex protein LAMTOR1 Ras homolog family member G Ras-related protein Rab-7a Rho GDP dissociation inhibitor beta Rho GDP dissociation inhibitor gamma Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 1 Rho GTPase activating protein 21 Rho GTPase activating protein 32 Rho GTPase activating protein 5 Rho GTPase-activating protein 35 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 5 Serine hydroxymethyltransferase Serine/threonine-protein kinase PAK 2 Starch-binding domain-containing protein 1 Synaptobrevin homolog YKT6 Syntaxin-5 Transferrin receptor protein 1 Triple functional domain protein Vang-like protein Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein-associated protein B non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase receptor protein-tyrosine kinase	A0A0G2JVP1 A0A0G2JYR5 A0A0G2K7N9 A0A8I5ZK89 A0A8I5ZNR8 A0A8I5ZPB5 A0A8I5ZRJ5 A0A8I5ZRT6 A0A8I5ZXI2 A0A8I6A4W2 A0A8I6A9Q4 A0A8I6AEP6 A0A8I6AG90 A0A8I6AM38 A0A8I6GDA1 A0A8I6GLR6 A0A8J8XFB5 A0A8J8XIU8 A1A5P0 B2GUW2 B5DF62 D3ZA21 D3ZBN3 D3ZG43 D3ZKC8 D3ZYG0 D4A1D2 D4A8H8 D4AA32 E9PT59 F1LVW7 F1M0Z1 F1M4N6 F1MAK3 G3V982 P09527 P0CAX5 P26772 P41350 P49134 P54100 P63025 P70496 P81128 P97924 Q08851 Q32PX6 Q4KLN7 Q5EGY4 Q5FVN1 Q5U2Y3 Q5U3Z7 Q5XI73 Q5XIN6 Q5XIU9 Q62902 Q63190 Q63362 Q63406 Q63787 Q64303 Q66HA1 Q6P791 Q7TP65 Q8CFN2 Q99376 Q9EPF2 Q9WVE9 Q9Z1X1 Q9Z269	AABR07021955.1 Ankle2 Arfgap3 Arhgap1 Arhgap21 Arhgap32 Arhgap35 Arhgap5 Arhgdia Arhgdib Arhgdig Arhgef16 Arhgef26 Arhgef5 Borg5 Cav Cav1 Cdc42 Cdc42ep1 Cyfip1 Depdc1b Diaph3 Dock2 Dock3 Dock4 Dock5 Dsg2 Duo Ehsh1 Elmo2 Emd Epha2 Ergic53 Esyt1 Fam62a Garre1 Grlf1 Hapip Hspe1 Iqgap2 Itgb1 Itsn Itsn1 Kalrn Ktn1 LOC687105 Lamtor1 Lbr Lem4 Letm1 Lman1 Map3k11 Mbc2 Mcam Mcf2 Mcf2l Mlk3 Mpp7 Muc18 Ndufa5 Ndufs3 Ophn1 Ost P190A Pak2 Pak4 Pgrmc2 Pik3r1 Pld1 Plekhg3 Prex1 Rab7 Rab7a Rbm39 Rhog Shmt2 Stbd1 Stx5 Stx5a Syb3 Tfrc Trfr Trio Vamp3 Vangl1 Vapb Vav Vav1 Vav2 Vav3 Vrk2 Ykt6 p190ARHOGAP	Rattus norvegicus (Norway rat)
CaMK IV-mediated phosphorylation of CREB	Calcium/calmodulin-dependent protein kinase kinase 1 Calcium/calmodulin-dependent protein kinase kinase 2 Calcium/calmodulin-dependent protein kinase type IV Calmodulin-3	O88831 P0DP31 P13234 P97756	CaMIII Calm3 Cam3 Camc Camk4 Camkk1 Camkk2	Rattus norvegicus (Norway rat)
Type II Na+/Pi cotransporters	Sodium-dependent phosphate transport protein 2A Sodium-dependent phosphate transport protein 2B Sodium-dependent phosphate transport protein 2C	Q06496 Q8K4R8 Q9JJ09	Slc17a2 Slc34a1 Slc34a2 Slc34a3	Rattus norvegicus (Norway rat)
SHC-mediated cascade:FGFR4	Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Klotho beta SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	A0A8I6B5D5 D3Z8T6 D4A3T0 F1LSQ8 O54769 O88182 P08644 P13109 P20171 P36364 P61149 P62994 P63076 Q04970 Q498D6 Q5M824 Q8R5L5 Q8VI81 Q8VI82 Q9EST9	Ash FGF15 FGF6 Fgf-1 Fgf-2 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf19 Fgf2 Fgf20 Fgf23 Fgf4 Fgf6 Fgf7a Fgf7b Fgf8 Fgf8a Fgf9 Fgfa Fgfr4 Grb2 Hras Hras1 Klb Kras Kras2 Nras Shc1 Sos1	Rattus norvegicus (Norway rat)
Beta oxidation of myristoyl-CoA to lauroyl-CoA	Long-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P15650 Q60587 Q64428	Acadl Hadha Hadhb	Rattus norvegicus (Norway rat)
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA	Enoyl-CoA hydratase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Long-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P14604 P15650 Q60587 Q64428 Q9WVK7	Acadl Echs1 Had Hadh Hadha Hadhb Hadhsc Schad	Rattus norvegicus (Norway rat)
Regulation of RAS by GAPs	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-3 Disabled homolog 2-interacting protein GTPase HRas GTPase KRas GTPase NRas Kelch repeat and BTB domain containing 7 Neurofibromin Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta RAS p21 protein activator 4 RAS protein activator like 1 RAS protein activator like 2 RAS protein activator like 3 Ras GTPase-activating protein 1 Ras GTPase-activating protein 2 Ras GTPase-activating protein 3 Ras/Rap GTPase-activating protein SynGAP Ring-box 1 Spred3 protein Sprouty-related, EVH1 domain containing 1 Sprouty-related, EVH1 domain-containing protein 2 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2JUC8 A0A0G2KAX0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I6A4X6 A0A8I6A5Y3 A0A8I6AI87 A0A8I6AT07 A0A8I6GE24 B0BN93 B2GV40 B5DF89 D3ZHY9 D3ZQH9 F1LMQ3 F1LMZ8 F1M6I7 F7FGV7 G3V6W6 G3V8G2 O88761 P08644 P0CG51 P17220 P18420 P18421 P18422 P20171 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P50904 P60901 P62193 P62198 P62982 P97526 Q04970 Q3C2P8 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63713 Q63797 Q63798 Q6P730 Q9JHW0 Q9QUH6 Q9QYJ2 Q9WTV5 Q9Z2X3	Cul3 Dab2ip Hras Hras1 Kbtbd7 Kras Kras2 LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Mecl1 Mss1 Nf1 Nras Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Rasa Rasa1 Rasa2 Rasa3 Rasa4 Rasal1 Rasal2 Rasal3 Rbx1 Ring12 Rps27a Spred1 Spred2 Spred3 Sug1 Syngap1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
DNA Damage Recognition in GG-NER	Actin, cytoplasmic 1 Actin-like 6A Actin-related protein 5 Actin-related protein 8 COP9 signalosome complex subunit 1 COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 3 COP9 signalosome complex subunit 4 COP9 signalosome complex subunit 6 COP9 signalosome complex subunit 8 COP9 signalosome subunit 5 COP9 signalosome subunit 7A COP9 signalosome subunit 7B Centrin 2 Chromatin-remodeling ATPase INO80 Cullin 4A Cullin 4B DNA damage-binding protein 1 DNA damage-binding protein 2 INO80 complex subunit B INO80 complex subunit C INO80 complex subunit D INO80 complex subunit E Microspherule protein 1 Nuclear factor related to kappa B binding protein Poly (ADP-ribose) polymerase 2 Poly [ADP-ribose] polymerase 1 Polyubiquitin-B Polyubiquitin-C Ring-box 1 RuvB-like 1 TCF3 fusion partner homolog Transcription factor YY1 UV excision repair protein RAD23 homolog B UV excision repair protein RAD23 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein XPC complex subunit, DNA damage recognition and repair factor	A0A0G2JUC8 A0A8I5YBR2 A0A8I6A524 A0A8I6A5Y3 D3ZAQ1 D3ZK73 D3ZR08 D3ZTM2 D3ZU52 D3ZVT1 D4A3D8 D4A421 D4A6Q6 F1MAA2 F7EUU4 F7FBV1 F7FJT3 F7FNG5 G3V749 G3V9W0 P0CG51 P27008 P60123 P60711 P61203 P62982 P97834 Q4KM87 Q4KMA2 Q5BJY3 Q63429 Q68FS2 Q68FW9 Q6AYH2 Q6P4Z9 Q8CHJ4 Q9ESW0 Q9JMG6	Actb Actl6a Actr5 Actr8 Adprt Amida Ccdc95 Cetn2 Cops1 Cops2 Cops3 Cops4 Cops5 Cops6 Cops7a Cops7b Cops8 Csn1 Csn2 Csn3 Csn4 Csn8 Cul4a Cul4b Ddb1 Ddb2 Gps1 Ino80 Ino80b Ino80c Ino80d Ino80e LOC100360645 Mcrs1 Nfrkb Parp1 Parp2 Rad23a Rad23b Rbx1 Rps27a Ruvbl1 Tfpt Tip49 Tip49a Trip15 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Xpc Yy1 yy1	Rattus norvegicus (Norway rat)
Maturation of TCA enzymes and regulation of TCA cycle	Acetyl-CoA acetyltransferase, mitochondrial Aconitate hydratase, mitochondrial Frataxin, mitochondrial Isocitrate dehydrogenase [NADP], mitochondrial Sirtuin 3 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Succinate dehydrogenase assembly factor 2, mitochondrial	A0A8I5XWT5 D3ZYW7 P17764 P56574 Q5RJQ7 Q920L2 Q9ER34	Acat1 Aco2 Fxn Idh2 Pgl2 Sdh5 Sdha Sdhaf2 Sirt3	Rattus norvegicus (Norway rat)
Muscarinic acetylcholine receptors	Muscarinic acetylcholine receptor M1 Muscarinic acetylcholine receptor M2 Muscarinic acetylcholine receptor M3 Muscarinic acetylcholine receptor M4 Muscarinic acetylcholine receptor M5	P08482 P08483 P08485 P08911 P10980	Chrm-1 Chrm-2 Chrm-3 Chrm-4 Chrm-5 Chrm1 Chrm2 Chrm3 Chrm4 Chrm5	Rattus norvegicus (Norway rat)
Negative regulation of the PI3K/AKT network	Acyl-coenzyme A thioesterase THEM4 PH domain leucine-rich repeat protein phosphatase 1 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Tribbles homolog 3	A0A8I6AU71 P47196 P47197 Q566R0 Q63484 Q9WTQ6 Q9WTR8	Akt1 Akt2 Akt3 Nipk Phlpp Phlpp1 Plekhe1 Pten Scop Them4 Trib3	Rattus norvegicus (Norway rat)
NGF processing	Beta-nerve growth factor Furin Proprotein convertase subtilisin/kexin type 5 Proprotein convertase subtilisin/kexin type 6	P23377 P25427 P41413 Q63415	Fur Furin Ngf Ngfb Pace4 Pcsk3 Pcsk5 Pcsk6	Rattus norvegicus (Norway rat)
Class A/1 (Rhodopsin-like receptors)	2-oxoglutarate receptor 1 Cannabinoid receptor 1 Cannabinoid receptor 2 Chemerin-like receptor 1 G protein-coupled receptor 132 G protein-coupled receptor 35 G protein-coupled receptor 39 G protein-coupled receptor 55 G protein-coupled receptor 68 G-protein coupled bile acid receptor 1 G-protein coupled receptor 183 G-protein coupled receptor 4 G-protein coupled receptor 65 Hydroxycarboxylic acid receptor 2 Melatonin receptor type 1B N-arachidonyl glycine receptor Platelet-activating factor receptor Succinate receptor 1	A0A8I6A964 A0A8J8Y1V6 A1A5S3 B0YIR8 D3ZSW1 D4A7K7 F1MAK4 G3V962 O35786 P20272 P46002 P49287 Q4KLH9 Q6IYF9 Q6Y1R5 Q80T02 Q80Z39 Q9QZN9	Cmklr1 Cnr1 Cnr2 Dez Ebi2 Gpbar1 Gpr109 Gpr109a Gpr109b Gpr132 Gpr18 Gpr183 Gpr35 Gpr39 Gpr4 Gpr55 Gpr65 Gpr68 Gpr80 Gpr91 Hcar2 Mt2 Mtnr1b Niacr1 Oxgr1 P2y15 Ptafr Pumag Skr6 Sucnr1 Tgr5	Rattus norvegicus (Norway rat)
Passive transport by Aquaporins	Aquaporin 10 Aquaporin-11 Aquaporin-1 Aquaporin-2 Aquaporin-3 Aquaporin-4 Aquaporin-5 Aquaporin-7 Aquaporin-8 Aquaporin-9 Aquaporin Lens fiber major intrinsic protein (Fragment)	A0A8I6A7W7 D4A9T6 P09011 P29975 P34080 P47862 P47863 P47864 P56403 P56405 P56627 Q8CHM1	Aqp1 Aqp10 Aqp11 Aqp12a Aqp2 Aqp3 Aqp4 Aqp5 Aqp7 Aqp8 Aqp9 Chip28 LOC686596 Mip	Rattus norvegicus (Norway rat)
The activation of arylsulfatases	Arylsulfatase A Arylsulfatase B Arylsulfatase E Arylsulfatase G Arylsulfatase I Arylsulfatase K Arylsulfatase family, member J Steryl-sulfatase Sulfatase modifying factor 1 Sulfatase modifying factor 2	A0A1W2Q645 D4A7I8 P15589 P50430 Q32KJ2 Q32KJ7 Q32KJ8 Q32KJ9 Q32KK0 Q32KK2	AABR07013255.1 Arsa Arsb Arse Arsg Arsi Arsj Arsk Arsl Sts Sumf1 Sumf2	Rattus norvegicus (Norway rat)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	Aldo-keto reductase family 1 member C21 Aldo-keto reductase family 1, member C1 Carbonyl reductase [NADPH] 1 Cytochrome P450 family 8 subfamily B member 1 Hematopoietic prostaglandin D synthase Prostacyclin synthase Prostaglandin E synthase 2 Prostaglandin E synthase 3 Prostaglandin E synthase Prostaglandin G/H synthase 1 Prostaglandin G/H synthase 2 Prostaglandin-H2 D-isomerase Thromboxane-A synthase	D4AE56 G3V8J2 O35543 P22057 P35355 P47727 P49430 P83868 Q3MHS3 Q62969 Q63921 Q6AYQ2 Q9JHF3	Akr1c1 Akr1c21 Cbr Cbr1 Cox-1 Cox-2 Cox1 Cox2 Cyp5 Cyp5a1 Cyp8 Cyp8b1 Gsts Hpgds Hsd17b5 Pgds Pges Pig12 Ptgds Ptgds2 Ptges Ptges2 Ptges3 Ptgis Ptgs1 Ptgs2 Tbxas1 Tebp	Rattus norvegicus (Norway rat)
PECAM1 interactions	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Integrin beta-3 Integrin subunit alpha V Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Platelet endothelial cell adhesion molecule Proto-oncogene tyrosine-protein kinase LCK Proto-oncogene tyrosine-protein kinase Src Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6	F1LM93 F1LZX9 P10686 P41499 P81718 P97573 Q01621 Q07014 Q3SWT0 Q62844 Q8R2H2 Q9WUD9	Fyn Inpp5d Itgav Itgb3 Lck Lyn Pecam Pecam1 Plcg1 Ptph6 Ptpn11 Ptpn6 Ship Ship1 Src Yes1	Rattus norvegicus (Norway rat)
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Beta-transducin repeat containing E3 ubiquitin protein ligase Cullin 1 Glycogen synthase kinase-3 beta Nuclear factor erythroid 2-related factor 2 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Ring-box 1 S-phase kinase-associated protein 1 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2JUC8 A0A8I5Y0H0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I6A5Y3 A0A8I6G2R1 B0BN93 F1LMQ3 F1LMZ8 F7FGV7 G3V6W6 G3V8G2 O54968 O88761 P0CG51 P17220 P18266 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q6PEC4 Q9JHW0 Q9WTV5 Q9Z2X3	Btrc Cul1 Gsk3b LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Mecl1 Mss1 Nfe2l2 Nrf2 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psmf1 Rbx1 Ring12 Rps27a Skp1 Skp1a Sug1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
RAF activation	14-3-3 protein beta/alpha BRCA1 associated protein Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-3 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 GTPase HRas GTPase KRas GTPase NRas Kinase suppressor of ras 1 Leucine-rich repeat protein SHOC-2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase kinase kinase 11 Prohibitin 1 Protein phosphatase 2 scaffold subunit A alpha Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras-related protein M-Ras Serine/threonine-protein kinase A-Raf Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase PP1-beta catalytic subunit Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Tyrosine-protein kinase JAK2 non-specific serine/threonine protein kinase	A0A8I5Y120 A0A8I5ZMG6 A0A8I5ZQW6 A0A8I5ZRC2 A0A8I6A6K6 A0A8I6ATH0 D3ZDI7 P08413 P08644 P0DP31 P11275 P11345 P11730 P14056 P15791 P20171 P35213 P36506 P62142 P62716 P63088 P63331 P67779 P97538 Q01986 Q04970 Q4QQT4 Q5XI34 Q62689 Q66HA1 Q6AYI5 Q80W83 Q8VHF0 Q9WUD9	A-raf Araf Araf1 Braf Brap CaMIII Calm3 Cam3 Camc Camk2a Camk2b Camk2d Camk2g Hras Hras1 Jak2 Kras Kras2 Ksr1 LOC100909468 Map2k1 Map2k2 Map3k11 Mark3 Mek1 Mek2 Mkk2 Mlk3 Mras Nras Phb Phb1 Ppp1cb Ppp1cc Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5a Ppp2r5b Ppp2r5c Ppp2r5d Ppp2r5e Prkmk1 Prkmk2 Raf Raf1 Rras3 Shoc2 Src Ywhab	Rattus norvegicus (Norway rat)
Regulation of the apoptosome activity	Apoptosis and caspase activation inhibitor Apoptotic protease-activating factor 1 Caspase-9 Cytochrome c domain-containing protein Cytochrome c, somatic Direct IAP-binding protein with low pI E3 ubiquitin-protein ligase XIAP Methylthioribulose-1-phosphate dehydratase Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Similar to Cytochrome c, somatic	A0A8I6AHX5 D3ZUI1 D3ZXV2 D4A5L9 D4A7Z5 P21708 P62898 P63086 Q9EPV5 Q9JHK1 Q9R0I6	AC128290.1 APIP Apaf1 Api3 Apip Aven Birc4 Casp9 Cycs Cycsl2 Cycsl3 Diablo Diablol1 Erk1 Erk2 LOC100360940 LOC690675 Mapk Mapk1 Mapk3 Prkm1 Prkm3 RGD1562558 RNCASP9 Xiap	Rattus norvegicus (Norway rat)
Phase I - Functionalization of compounds	Aldehyde dehydrogenase, dimeric NADP-preferring Amine oxidase [copper-containing] 3 Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor Arylacetamide deacetylase Biphenyl hydrolase like Carbonyl reductase [NADPH] 3 Carboxylesterase 1D Carboxylic ester hydrolase Carboxymethylenebutenolidase homolog Cytochrome P450 3A18 Cytochrome P450 3A1 Cytochrome P450 3A2 Cytochrome P450 3A9 Cytochrome P450 3A Cytochrome P450 Cytochrome b5 type B Diamine oxidase [copper-containing] Epoxide hydrolase 1 Mitochondrial amidoxime reducing component 2 NADH-cytochrome b5 reductase 3 Ribosyldihydronicotinamide dehydrogenase [quinone]	A0A0G2K5K4 B2GV72 F7FBS0 G3V9D2 M0R9W7 O08590 O88994 P04166 P04800 P05183 P07687 P11883 P16303 P20070 P36633 P41738 P41739 P51538 Q64581 Q6AY80 Q75NT5 Q78E60 Q7TP52 Q9QZH8	Aada Aadac Abp1 Ahr Ahrr Aldd Aldh3 Aldh3a1 Aoc1 Aoc3 Arnt Arnt2 Bphl Cbr3 Ces1d Ces2b Ces3 Cmbl Cyb5b Cyb5m Cyb5r3 Cyp2b21 Cyp3a-1 Cyp3a-2 Cyp3a1 Cyp3a11 Cyp3a13 Cyp3a18 Cyp3a2 Cyp3a62 Cyp3a9 Dia1 Eph-1 Ephx1 LOC679149 Marc2 Mg87 Mosc2 Mtarc2 Nqo2 Omb5	Rattus norvegicus (Norway rat)

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