GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **451 - 475** of **1070** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism
Cilium Assembly	Alpha-tubulin N-acetyltransferase 1	Q6MG11	Atat1 Mec17	Rattus norvegicus (Norway rat)
Sensory perception of salty taste	Amiloride-sensitive sodium channel subunit alpha Amiloride-sensitive sodium channel subunit beta Amiloride-sensitive sodium channel subunit gamma	P37089 P37090 P37091	Renac Scnn1a Scnn1b Scnn1g	Rattus norvegicus (Norway rat)
Norepinephrine Neurotransmitter Release Cycle	Amine oxidase [flavin-containing] A Complexin-1 Liprin-alpha-3 Liprin-alpha-4 (Fragment) PTPRF interacting protein alpha 1 PTPRF interacting protein alpha 2 Peripheral-type benzodiazepine receptor-associated protein 1 Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Solute carrier family 22 member 1 Solute carrier family 22 member 2 Synaptic vesicular amine transporter Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Syntaxin-binding protein 1 Vesicle-associated membrane protein 2	A0A1B0GWS0 A0A8I6AK94 P21396 P21707 P32851 P60881 P61765 P63012 P63041 P63045 Q01827 Q62769 Q63089 Q91Z79 Q91Z80 Q9JIR0 Q9JIR4 Q9R0W2	Bzrap1 Cplx1 Maoa Oct1 Oct2 Ppfia1 Ppfia2 Ppfia3 Ppfia4 Rab3a Rbp1 Rim1 Rims1 Sap Slc18a2 Slc22a1 Slc22a2 Snap Snap25 Stx1a Stxbp1 Svat Syb2 Syt1 Tspoap1 Unc13b Unc13h2 Unc18a Vamp2 Vmat2	Rattus norvegicus (Norway rat)
Clearance of dopamine	Amine oxidase [flavin-containing] A Sodium-dependent dopamine transporter	P21396 P23977	Maoa Slc6a3	Rattus norvegicus (Norway rat)
Amino acid transport across the plasma membrane	Amino acid transporter heavy chain SLC3A1 Amino acid transporter heavy chain SLC3A2 Asc-type amino acid transporter 1 Cationic amino acid transporter 3 High affinity cationic amino acid transporter 1 Large neutral amino acids transporter small subunit 1 Large neutral amino acids transporter small subunit 2 Large neutral amino acids transporter small subunit 4 Mitochondrial basic amino acids transporter Monocarboxylate transporter 10 Neutral amino acid transporter B(0) Proton-coupled amino acid transporter 1 Proton-coupled amino acid transporter 2 Sodium- and chloride-dependent betaine transporter Sodium- and chloride-dependent taurine transporter Sodium- and chloride-dependent transporter XTRP3 Sodium-coupled neutral amino acid symporter 1 Sodium-coupled neutral amino acid symporter 2 Sodium-coupled neutral amino acid transporter 3 Sodium-coupled neutral amino acid transporter 4 Sodium-coupled neutral amino acid transporter 5 Sodium-dependent neutral amino acid transporter B(0)AT1 Sodium-dependent neutral amino acid transporter B(0)AT2 Sodium-dependent neutral amino acid transporter B(0)AT3 Solute carrier family 36 member 4 Solute carrier family 43 member 1 Solute carrier family 7 member 11 Transporter Y+L amino acid transporter 1 Y+L amino acid transporter 2 b(0,+)-type amino acid transporter 1	A0A8I5ZKR1 A0A8I6A5L0 A0A8I6AB70 A0A8I6AUR9 A2VCW5 B1WBX5 D3ZJ25 D3ZMH7 O08812 P30823 P31643 P48056 P63116 P82252 Q08469 Q2A865 Q5HZE0 Q62687 Q63016 Q64093 Q64319 Q794F9 Q8K415 Q91Y77 Q924A5 Q9EQ25 Q9JHE5 Q9JHZ9 Q9JM15 Q9R0S5 Q9WVR6	Asc1 Ata1 Ata2 Ata3 Atrc1 Atrc3 B0at1 B0at3 Bat1 Cat3 Glnt Lat1 Lat2 Lat4 Lyaat1 Mct10 Mpe16 Nbat Ntt73 Ornt3 Pat2 Sa1 Sa2 Sat1 Sat2 Sit1 Slc16a10 Slc1a5 Slc25a29 Slc36a1 Slc36a2 Slc36a4 Slc38a1 Slc38a2 Slc38a3 Slc38a4 Slc38a5 Slc3a1 Slc3a2 Slc43a1 Slc43a2 Slc6a12 Slc6a14 Slc6a15 Slc6a18 Slc6a19 Slc6a20 Slc6a6 Slc7a1 Slc7a10 Slc7a11 Slc7a3 Slc7a5 Slc7a6 Slc7a7 Slc7a8 Slc7a9 Sn2 Snat1 Snat2 Snat3 Snat4 Snat5 Ta1 Tat1 Tramd1 Xtrp2 Xtrp3	Rattus norvegicus (Norway rat)
Basigin interactions	Amino acid transporter heavy chain SLC3A2 Asc-type amino acid transporter 1 Basigin Caveolin-1 Integrin alpha 3 variant B Integrin beta-1 Integrin subunit alpha 6 Large neutral amino acids transporter small subunit 1 Large neutral amino acids transporter small subunit 2 Leukosialin (Fragment) Monocarboxylate transporter 1 Monocarboxylate transporter 3 Monocarboxylate transporter 4 Myelin-associated glycoprotein Neural cell adhesion molecule L1 Peptidyl-prolyl cis-trans isomerase A RING-type E3 ubiquitin transferase Sodium/potassium-transporting ATPase subunit beta-1 Sodium/potassium-transporting ATPase subunit beta-2 Sodium/potassium-transporting ATPase subunit beta-3 Solute carrier family 7 member 11 Y+L amino acid transporter 1 Y+L amino acid transporter 2 b(0,+)-type amino acid transporter 1 interstitial collagenase	A0A8I5ZKR1 A0A8I6AB70 A0A8I6AJE9 B5DFD5 F7FHL6 I4DUB5 O35910 O70461 P07340 P07722 P10111 P13638 P13838 P26453 P41350 P49134 P53987 P63116 P82252 Q05695 Q63016 Q63377 Q794F9 Q9R0S5 Q9WVR6	Asc1 Atp1b1 Atp1b2 Atp1b3 Bat1 Bsg Caml1 Cav Cav1 ITGA3B Itga3 Itga6 Itgb1 L1cam Lat1 Lat2 Lat4 Mag Mct1 Mct3 Mct4 Mmp1 Mmp1a Mpe16 Ppia Ppil2 Slc16a1 Slc16a3 Slc16a8 Slc3a2 Slc7a10 Slc7a11 Slc7a5 Slc7a6 Slc7a7 Slc7a8 Slc7a9 Spn Ta1	Rattus norvegicus (Norway rat)
Glutamate Neurotransmitter Release Cycle	Amino acid transporter Complexin-1 Excitatory amino acid transporter 1 Excitatory amino acid transporter 2 Excitatory amino acid transporter 3 Excitatory amino acid transporter 4 Glutaminase kidney isoform, mitochondrial Glutaminase liver isoform, mitochondrial Liprin-alpha-3 Liprin-alpha-4 (Fragment) PRA1 family protein 3 PTPRF interacting protein alpha 1 PTPRF interacting protein alpha 2 Peripheral-type benzodiazepine receptor-associated protein 1 Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Sodium-coupled neutral amino acid symporter 2 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Syntaxin-binding protein 1 Vesicle-associated membrane protein 2 Vesicular glutamate transporter 1	A0A1B0GWS0 A0A8I6AK94 D3ZT83 O35921 P13264 P21707 P24942 P28492 P31596 P32851 P51907 P60881 P61765 P63012 P63041 P63045 Q62634 Q62769 Q91Z79 Q91Z80 Q9ES40 Q9JHE5 Q9JIR0 Q9JIR4	Arl6ip5 Ata2 Bnpi Bzrap1 Cplx1 Eaac1 Eaat1 Eaat2 Eaat3 Eaat4 Ga Gls Gls2 Glt1 Gtrap3-18 Jwa Ppfia1 Ppfia2 Ppfia3 Ppfia4 Pra2 Praf3 Rab3a Rbp1 Rim1 Rims1 Sa1 Sap Sat2 Slc17a7 Slc1a1 Slc1a2 Slc1a3 Slc1a6 Slc1a7 Slc38a2 Snap Snap25 Snat2 Stx1a Stxbp1 Syb2 Syt1 Tspoap1 Unc13b Unc13h2 Unc18a Vamp2 Vglut1	Rattus norvegicus (Norway rat)
Transport of inorganic cations/anions and amino acids/oligopeptides	Amino acid transporter Cystinosin, lysosomal cystine transporter Excitatory amino acid transporter 1 Excitatory amino acid transporter 2 Excitatory amino acid transporter 3 Excitatory amino acid transporter 4 Mitochondrial S-adenosylmethionine carrier protein Vesicular inhibitory amino acid transporter	A0A8I6AAR8 D3ZG79 D3ZT83 O35458 O35921 P24942 P31596 P51907	Ctns Eaac1 Eaat1 Eaat2 Eaat3 Eaat4 Glt1 Slc1a1 Slc1a2 Slc1a3 Slc1a6 Slc1a7 Slc25a26 Slc32a1 Vgat Viaat	Rattus norvegicus (Norway rat)
Rhesus glycoproteins mediate ammonium transport.	Ammonium transporter Rh type A Ammonium transporter Rh type B Ammonium transporter Rh type C	Q68FT6 Q7TNK7 Q7TNN9	Rh50 Rhag Rhbg Rhcg	Rattus norvegicus (Norway rat)
Erythrocytes take up carbon dioxide and release oxygen	Ammonium transporter Rh type A Aquaporin-1 Band 3 anion transport protein Carbonic anhydrase 1 Carbonic anhydrase 2 Carbonic anhydrase 4 Cytochrome b5 reductase 4 Hemoglobin subunit alpha-1/2 Hemoglobin subunit beta-1 NADH-cytochrome b5 reductase 1 NADH-cytochrome b5 reductase 2 cytochrome-b5 reductase	B0BNN3 D3ZZ05 P01946 P02091 P23562 P27139 P29975 P48284 Q5EB81 Q68EJ0 Q6AY12 Q7TNK7	Ae1 Aqp1 Ca1 Ca2 Ca4 Car1 Chip28 Cyb5r1 Cyb5r2 Cyb5r4 Cyb5rl Hba-a1 Hba1 Hbb Ncb5or Rh50 Rhag Slc4a1	Rattus norvegicus (Norway rat)
Erythrocytes take up oxygen and release carbon dioxide	Ammonium transporter Rh type A Aquaporin-1 Band 3 anion transport protein Carbonic anhydrase 1 Carbonic anhydrase 2 Carbonic anhydrase 4 Hemoglobin subunit alpha-1/2 Hemoglobin subunit beta-1	B0BNN3 P01946 P02091 P23562 P27139 P29975 P48284 Q7TNK7	Ae1 Aqp1 Ca1 Ca2 Ca4 Car1 Chip28 Hba-a1 Hba1 Hbb Rh50 Rhag Slc4a1	Rattus norvegicus (Norway rat)
Signaling by EGFR	Amphiregulin Angio-associated, migratory cell protein Betacellulin Family with sequence similarity 83, member A Family with sequence similarity 83, member B Family with sequence similarity 83, member D Leucine-rich repeats and immunoglobulin-like domains 1 Pro-epidermal growth factor Proepiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Protransforming growth factor alpha Receptor protein-tyrosine kinase	A0A8I6AQ55 D3ZF70 D3ZQN0 D4ABG0 G3V6K6 G3V7V2 M0RB60 P01134 P07522 P24338 Q06175 Q9WUD9 Q9Z0L5	Aamp Areg Btc Dtr Egf Egfr Ereg Fam83a Fam83b Fam83d Hbegf Hegfl Lrig1 Sdgf Src Tgfa	Rattus norvegicus (Norway rat)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Amphiregulin Betacellulin CD19 molecule CD86 molecule Cd80 molecule Estrogen receptor beta Estrogen receptor Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2-associated binding protein 1 GRB2-associated-binding protein 2 Growth factor receptor-bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Inducible T-cell costimulator Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor Insulin-1 Interleukin-1 receptor accessory protein Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-like 1 Interleukin-33 Kit ligand Klotho beta Klotho Mast/stem cell growth factor receptor Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Myeloid differentiation primary response protein MyD88 Neuregulin 3 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha Phosphatidylinositol 4-phosphate 5-kinase type-1 beta Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Phosphatidylinositol 5-phosphate 4-kinase type-2 beta Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Phosphoinositide-3-kinase adaptor protein 1 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B (Fragment) Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor Protein phosphatase 2 scaffold subunit A alpha Proto-oncogene tyrosine-protein kinase LCK Proto-oncogene tyrosine-protein kinase Src Proto-oncogene vav Protransforming growth factor alpha RAC-alpha serine/threonine-protein kinase Rac family small GTPase 2 Ras homolog family member G Ras-related C3 botulinum toxin substrate 1 Receptor protein-tyrosine kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Striatin T cell receptor associated transmembrane adaptor 1 T-cell-specific surface glycoprotein CD28 TNF receptor-associated factor 6 Tyrosine-protein kinase Fyn Tyrosine-protein phosphatase non-receptor type 11 non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A0G2JW59 A0A0G2JYX9 A0A0G2K210 A0A0G2K344 A0A8I5Y1H8 A0A8I5Y949 A0A8I5ZMG6 A0A8I5ZRC2 A0A8I6A1P8 A0A8I6A6K6 A0A8I6AQ55 A0A8I6B5D5 A0A8I6G1H3 B5DF45 D3Z8T6 D3ZAL7 D3ZDI7 D3ZSI8 D4A244 F1LNH2 F1LSG7 F1LSQ8 F1M784 F1MAL5 F7F6T0 G3V671 G3V6K6 O35531 O35569 O54769 O88182 O88370 O88377 P01134 P01322 P06211 P06494 P07522 P13109 P15127 P17945 P20786 P21581 P21708 P24338 P28576 P31042 P35570 P36364 P41499 P43322 P47196 P48807 P54100 P61149 P62716 P62994 P63076 P63086 P63331 P70483 P70492 P97523 Q01621 Q02195 Q04589 Q05028 Q05030 Q06175 Q32PX6 Q498D6 Q4QQT4 Q5CZZ9 Q5I6B8 Q5XI34 Q62611 Q62799 Q62844 Q62986 Q63116 Q63621 Q63787 Q63788 Q63789 Q66H70 Q6RUV5 Q6Y1S1 Q80W83 Q8R5L5 Q8R5L9 Q8VI79 Q8VI81 Q8VI82 Q9EQH1 Q9EST9 Q9R0I8 Q9R1T7 Q9WUD9 Q9Z0L5 Q9Z1L0 Q9Z2Y9	Ailim Akt1 Areg Ash Btc Cd19 Cd28 Cd80 Cd86 Dtr Egf Egfr Erbb2 Erbb3 Erbeta Ereg Erk1 Erk2 Esr Esr1 Esr2 Estr FGF15 FGF22 FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-7 Fgf-9 Fgf1 Fgf10 Fgf16 Fgf17 Fgf18 Fgf19 Fgf2 Fgf20 Fgf22 Fgf23 Fgf3 Fgf4 Fgf5 Fgf5c Fgf5d Fgf6 Fgf7 Fgf7a Fgf7b Fgf8 Fgf8a Fgf9 Fgfa Fgfr1 Fgfr2 Fgfr3 Fgfr4 Fit1 Flg Flt3 Frs2 Fyn Gab1 Gab2 Grb2 Hbegf Hegfl Hgf Icos Il1rap Il1rl1 Il33 Ins-1 Ins1 Insr Irak1 Irak4 Irs-1 Irs1 Irs2 KIT Kgf Kit Kitl Kitlg Kl Klb LOC100361758 LOC100909468 Lck Mapk Mapk1 Mapk3 Met Mgf Myd88 Ndf Neu Nr3a1 Nr3a2 Nrg1 Nrg2 Nrg3 Ntak Pdgfa Pdgfb Pdgfr Pdgfr1 Pdgfra Pdgfrb Pik3ap1 Pik3ca Pik3cb Pik3cd Pik3r1 Pik3r2 Pik3r3 Pip4k2a Pip4k2b Pip4k2c Pip4ka Pip5k1a Pip5k1b Pip5k1c Pip5k2a Pip5k2b Pip5k2c Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5a Ppp2r5b Ppp2r5c Ppp2r5d Ppp2r5e Prkm1 Prkm3 Ptpn11 Rac Rac1 Rac2 Rhog Rpa1 Sdgf Src Strn Tgfa Traf6 Trat1 Vav Vav1	Rattus norvegicus (Norway rat)
EGFR downregulation	Amphiregulin Betacellulin Cell division control protein 42 homolog E3 ubiquitin-protein ligase CBL Endophilin-A1 Endophilin-A2 Endophilin-A3 Epidermal growth factor receptor pathway substrate 15-like 1 Epidermal growth factor receptor pathway substrate 15 Epsin-1 Growth factor receptor-bound protein 2 Hepatocyte growth factor-regulated tyrosine kinase substrate Polyubiquitin-B Polyubiquitin-C Pro-epidermal growth factor Proepiregulin Proheparin-binding EGF-like growth factor Protein sprouty homolog 1 Protein sprouty homolog 2 Protransforming growth factor alpha Receptor protein-tyrosine kinase Rho guanine nucleotide exchange factor 7 SH3 domain-containing kinase-binding protein 1 Signal transducing adapter molecule 2 Signal transducing adaptor molecule Tyrosine-protein phosphatase non-receptor type 12 Tyrosine-protein phosphatase non-receptor type Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A8I5YC99 A0A8I6A5Y3 A0A8I6A726 A0A8I6AQ55 A0A8I6G3R2 B5DF55 B5DFH3 F1LQQ5 G3V6K6 G3V7Q4 O35179 O35180 O35964 O55043 O88339 P01134 P07522 P0CG51 P24338 P62982 P62994 Q06175 Q5HZA2 Q5XHY7 Q63429 Q8CFN2 Q925Q9 Q9JJ50 Q9Z0L5	Areg Arhgef7 Ash Btc Cbl Cdc42 Dtr Egf Egfr Epn1 Eps15 Eps15l1 Ereg Grb2 Hbegf Hegfl Hgs Hrs Hrs2 LOC100360645 Pak3bp Pixb Ptpn12 Ptpn3 Rps27a Ruk Sdgf Seta Sh3d2a Sh3d2c1 Sh3gl1 Sh3gl2 Sh3gl3 Sh3kbp1 Sh3p13 Sh3p4 Sh3p8 Spry1 Spry2 Stam Stam2 Tgfa Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
GAB1 signalosome	Amphiregulin Betacellulin GRB2-associated binding protein 1 Growth factor receptor-bound protein 2 Paxillin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 Pro-epidermal growth factor Proepiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Protransforming growth factor alpha Receptor protein-tyrosine kinase Tyrosine-protein kinase CSK Tyrosine-protein phosphatase non-receptor type 11	A0A0G2K344 A0A8I6AQ55 D3ZAL7 G3V6K6 P01134 P07522 P24338 P32577 P41499 P62994 Q06175 Q63787 Q66H76 Q9JM80 Q9WUD9 Q9Z0L5	Areg Ash Btc Cbp Csk Dtr Egf Egfr Ereg Gab1 Grb2 Hbegf Hegfl Pag Pag1 Pik3ca Pik3r1 Ptpn11 Pxn Sdgf Src Tgfa	Rattus norvegicus (Norway rat)
SHC1 events in EGFR signaling	Amphiregulin Betacellulin GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Pro-epidermal growth factor Proepiregulin Proheparin-binding EGF-like growth factor Protransforming growth factor alpha Receptor protein-tyrosine kinase SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	A0A8I6AQ55 D4A3T0 G3V6K6 P01134 P07522 P08644 P20171 P24338 P62994 Q04970 Q06175 Q5M824 Q9Z0L5	Areg Ash Btc Dtr Egf Egfr Ereg Grb2 Hbegf Hegfl Hras Hras1 Kras Kras2 Nras Sdgf Shc1 Sos1 Tgfa	Rattus norvegicus (Norway rat)
GRB2 events in EGFR signaling	Amphiregulin Betacellulin GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Pro-epidermal growth factor Proepiregulin Proheparin-binding EGF-like growth factor Protransforming growth factor alpha Receptor protein-tyrosine kinase SOS Ras/Rac guanine nucleotide exchange factor 1	A0A8I6AQ55 D4A3T0 G3V6K6 P01134 P07522 P08644 P20171 P24338 P62994 Q04970 Q06175 Q9Z0L5	Areg Ash Btc Dtr Egf Egfr Ereg Grb2 Hbegf Hegfl Hras Hras1 Kras Kras2 Nras Sdgf Sos1 Tgfa	Rattus norvegicus (Norway rat)
GRB2:SOS provides linkage to MAPK signaling for Integrins	Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin Focal adhesion kinase 1 Growth factor receptor-bound protein 2 Integrin beta-3 Integrin subunit alpha 2b Proto-oncogene tyrosine-protein kinase Src Ras-related protein Rap-1A Ras-related protein Rap-1b SOS Ras/Rac guanine nucleotide exchange factor 1 Talin 1	A0A8I6ABG6 A0A8I6GGN2 D3ZDZ1 D4A3T0 O35346 P02680 P04937 P06399 P14480 P62836 P62994 Q62636 Q8R2H2 Q9WUD9	Apbb1ip Ash Fak Fak1 Fga Fgb Fgg Fn1 Grb2 Itga2b Itgb3 Krev1 Ptk2 Rap1a Rap1b Sos1 Src Tln1	Rattus norvegicus (Norway rat)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	Amyloid beta precursor protein binding family B member 1 BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 Breast cancer type 1 susceptibility protein homolog Bromodomain adjacent to zinc finger domain, 1B Cellular tumor antigen p53 DNA repair protein RAD50 Double-strand break repair protein MRE11 E3 ubiquitin-protein ligase RNF168 E3 ubiquitin-protein ligase RNF8 Eyes absent homolog Eyes absent homolog Eyes absent homolog Eyes absent homolog HECT-type E3 ubiquitin transferase Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H4 Histone acetyltransferase KAT5 Lys-63-specific deubiquitinase BRCC36 Mediator of DNA damage checkpoint protein 1 Mitogen-activated protein kinase 8 Nibrin Nuclear receptor binding SET domain protein 2 Polyubiquitin-B Polyubiquitin-C Protein inhibitor of activated STAT, 4 SUMO-conjugating enzyme UBC9 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 Serine-protein kinase ATM Serine/threonine-protein phosphatase 5 Small ubiquitin-related modifier 1 Tumor protein p53 binding protein 1 Tyrosine-protein kinase UBX domain-containing protein 1 Ubiquitin B-like Ubiquitin carboxyl-terminal hydrolase BAP1 Ubiquitin-conjugating enzyme E2 variant 2 Ubiquitin-ribosomal protein eS31 fusion protein [histone H3]-trimethyl-L-lysine(9) demethylase [histone H3]-trimethyl-L-lysine(9) demethylase	A0A0G2JUC9 A0A0G2JXI9 A0A0G2JZ01 A0A0G2K5I7 A0A8I5ZQQ5 A0A8I5ZSA8 A0A8I6A2W1 A0A8I6A5Y3 A0A8I6A7P3 A0A8I6AFW8 A0A8I6ALC2 B2RYM5 B2RYR0 B5DFF9 D3ZHS6 D3ZVI5 D3ZXP3 D4A9J4 D4ACL8 E9PT20 E9PTJ3 F1LX86 F1M842 G3V9C7 M0RB75 M0RBQ5 O54952 P0CG51 P10361 P46933 P49185 P53042 P62804 P62982 P63281 Q00729 Q499N6 Q4KLN8 Q5I0F1 Q5I0H3 Q5PQK4 Q5U2M8 Q5XIJ6 Q63429 Q6P7Q1 Q7M767 Q99MK2 Q9JIL8 Q9JIL9 Q9JIM0 Q9QZH2	ABRAXAS1 Abl1 Abra1 Apbb1 Atm Babam1 Babam2 Bap1 Bard1 Baz1b Brca1 Brcc3 Brcc36 Bre Ccdc98 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 Eya1 Eya2 Eya3 Eya4 Fam175a Fe65 H2afx H2ax H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H4c16 H4c2 H4f16 H4ft Herc2 Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist4 Hist4h4 Htatip Jnk1 Kat5 Kdm4a Kdm4b LOC100360645 LOC100365043 LOC100910200 LOC684797 Mapk8 Mdc1 Merit40 Mms2 Mre11 Mre11a Nba1 Nbn Nbs1 Nsd2 P53 Pias4 Ppp5c Prkm8 Rad50 Rap80 Rir Rnf168 Rnf8 Rps27a Saks1 Smarca5 Sumo1 Th2b Tip60 Tip60b Tp53 Tp53bp1 Uba80 Ubb Ubbl1 Ubc Ubce9 Ubcep1 Ubcl1 Ube2i Ube2v2 Ubxn1 Uev2 Uimc1 Whsc1	Rattus norvegicus (Norway rat)
Dopamine Neurotransmitter Release Cycle	Amyloid-beta A4 precursor protein-binding family A member 1 Complexin-1 Liprin-alpha-3 Liprin-alpha-4 (Fragment) PTPRF interacting protein alpha 1 PTPRF interacting protein alpha 2 Peripheral plasma membrane protein CASK Peripheral-type benzodiazepine receptor-associated protein 1 Protein lin-7 homolog A Protein lin-7 homolog B Protein lin-7 homolog C Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Synapsin-1 Synapsin-2 Synapsin-3 Synaptic vesicular amine transporter Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Syntaxin-binding protein 1 Vesicle-associated membrane protein 2	A0A1B0GWS0 A0A8I6AK94 O35430 O70441 P09951 P21707 P32851 P60881 P61765 P63012 P63041 P63045 Q01827 Q62769 Q62915 Q63537 Q792I0 Q91Z79 Q91Z80 Q9JIR0 Q9JIR4 Q9Z250 Q9Z252	Apba1 Bzrap1 Cask Cplx1 Lin7a Lin7b Lin7c Mals1 Mals2 Mals3 Mint1 Ppfia1 Ppfia2 Ppfia3 Ppfia4 Rab3a Rbp1 Rim1 Rims1 Sap Slc18a2 Snap Snap25 Stx1a Stxbp1 Svat Syb2 Syn1 Syn2 Syn3 Syt1 Tspoap1 Unc13b Unc13h2 Unc18a Vamp2 Veli1 Veli1a Veli2 Veli3 Vmat2 X11	Rattus norvegicus (Norway rat)
Formyl peptide receptors bind formyl peptides and many other ligands	Amyloid-beta precursor protein Annexin A1 C-C motif chemokine 6 C-C motif chemokine ligand 9 Formyl peptide receptor 2 like 2 Formyl peptide receptor 2 Heme-binding protein 1 fMet-Leu-Phe receptor	A0A8I6AM80 B4F7C7 D4A7Q2 D4A942 P07150 P08592 Q5FVN3 Q68FP3	A4 AD1 Anx1 Anxa1 App Ccl6 Ccl9 Fpr1 Fpr2 Fpr2l3 Hebp1	Rattus norvegicus (Norway rat)
APC-Cdc20 mediated degradation of Nek2A	Anaphase promoting complex subunit 1 Anaphase promoting complex subunit 7 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit CDC26 BUB1 mitotic checkpoint serine/threonine kinase B Cell division cycle 16 Cell division cycle 23 Cell division cycle protein 20 homolog Cell division cycle protein 27 homolog E2 ubiquitin-conjugating enzyme Mitotic arrest deficient 2 like 1 Polyubiquitin-B Polyubiquitin-C Ubiquitin B-like Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eS31 fusion protein non-specific serine/threonine protein kinase	A0A8I6A4J8 A0A8I6A5Y3 A0A8I6AE10 A0A8I6AHQ6 A0A8I6ANL9 A1L1K3 B5DFI8 D3ZDK2 D3ZDN9 D3ZIT4 D3ZQX4 D3ZUB7 D3ZUW6 D4ACM2 F1LMI1 F1M3L4 F7EWF8 P0CG51 P62982 Q4V8A2 Q62623 Q63429 Q6YDN7	Anapc1 Anapc15 Anapc16 Anapc2 Anapc4 Anapc5 Anapc7 Bub1b Cdc16 Cdc20 Cdc23 Cdc26 Cdc27 LOC100360645 LOC100366017 Mad2l1 Nek2l1 Rps27a Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Ube2c Ube2d1 Ube2e1 Ube2s	Rattus norvegicus (Norway rat)
Inactivation of APC/C via direct inhibition of the APC/C complex	Anaphase promoting complex subunit 1 Anaphase promoting complex subunit 7 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit CDC26 BUB1 mitotic checkpoint serine/threonine kinase B Cell division cycle 16 Cell division cycle 23 Cell division cycle protein 20 homolog Cell division cycle protein 27 homolog E2 ubiquitin-conjugating enzyme Mitotic arrest deficient 2 like 1 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 S	A0A8I6A4J8 A0A8I6AE10 A0A8I6ANL9 A1L1K3 B5DFI8 D3ZDK2 D3ZDN9 D3ZIT4 D3ZQX4 D3ZUB7 D3ZUW6 D4ACM2 F1LMI1 F1M3L4 F7EWF8 Q4V8A2 Q62623 Q6YDN7	Anapc1 Anapc15 Anapc16 Anapc2 Anapc4 Anapc5 Anapc7 Bub1b Cdc16 Cdc20 Cdc23 Cdc26 Cdc27 LOC100366017 Mad2l1 Ube2c Ube2d1 Ube2e1 Ube2s	Rattus norvegicus (Norway rat)
Senescence-Associated Secretory Phenotype (SASP)	Anaphase promoting complex subunit 1 Anaphase promoting complex subunit 7 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit CDC26 CCAAT/enhancer-binding protein beta Cell division cycle 16 Cell division cycle 23 Cell division cycle protein 27 homolog Cyclin dependent kinase inhibitor 2D Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase inhibitor 1A Cyclin-dependent kinase inhibitor 1B E2 ubiquitin-conjugating enzyme Euchromatic histone lysine methyltransferase 1 Euchromatic histone lysine methyltransferase 2 Fizzy and cell division cycle 20 related 1 Histone H2A type 2-A Histone H2A.J Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H3.1 Histone H3.3 Histone H3 Histone H4 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 7 Polyubiquitin-B Polyubiquitin-C Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase Ribosomal protein S6 kinase Ubiquitin B-like Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JVY9 A0A0G2JXI9 A0A0G2K889 A0A8I5ZSA8 A0A8I5ZYY0 A0A8I5ZZ18 A0A8I6A2W1 A0A8I6A4J8 A0A8I6A5Y3 A0A8I6A7P3 A0A8I6AE10 A0A8I6AFW8 A0A8I6ANL9 A0A8I6AR08 A0A8I6AWJ2 A0A8I6AWT3 A0A8I6G659 A0A8J8XWH8 A1L1K3 A9UMV8 B1WCA1 B5DFI8 D3ZDK2 D3ZDN9 D3ZIT4 D3ZJ08 D3ZQX4 D3ZUB7 D3ZUW6 D3ZVK7 D3ZXP3 D4ACM0 F1M3L4 F1MA87 F7EWF8 G3V9C7 M0RBQ5 O08769 P0C865 P0CC09 P0CG51 P21272 P21708 P35426 P55272 P62804 P62982 P63086 P84245 Q00729 Q4V8A2 Q63429 Q63531 Q63699 Q6AY13 Q6LED0 Q6P4Z7 Q6YDN7	Anapc1 Anapc15 Anapc16 Anapc2 Anapc4 Anapc5 Anapc7 Bmk1 Ccna1 Ccna2 Cdc16 Cdc23 Cdc26 Cdc27 Cdk2 Cdk4 Cdk6 Cdkn1a Cdkn1b Cdkn2 Cdkn2b Cdkn2d Cebpb Crp2 ENSRNOG00000062927 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 Ehmt1 Ehmt2 Erk1 Erk2 Erk5 Fzr1 H2ab3 H2ac10 H2ac18 H2ac4 H2afb3 H2afx H2aj H2ax H2az2 H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H3-3b H3.3b H3c13 H3f3b H4c16 H4c2 H4f16 H4ft Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist2h2aa3 Hist2h3c2 Hist4 Hist4h4 Ink4 LOC100360645 LOC100365043 LOC100366017 LOC100910200 LOC120097726 LOC684797 Mapk Mapk1 Mapk3 Mapk7 Mapkapk1a Nf-il6 Prkm1 Prkm3 Rps27a Rps6ka1 Rps6ka2 Rps6ka3 Rsk1 Sfb Th2b Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Ube2c Ube2d1 Ube2e1 Ube2s p27Kip1	Rattus norvegicus (Norway rat)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	Anaphase promoting complex subunit 1 Anaphase promoting complex subunit 7 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit CDC26 Cell division cycle 14A Cell division cycle 16 Cell division cycle 23 Cell division cycle protein 20 homolog Cell division cycle protein 27 homolog E2 ubiquitin-conjugating enzyme Fizzy and cell division cycle 20 related 1 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 S	A0A8I6A4J8 A0A8I6AE10 A0A8I6ANL9 A0A8I6B415 A1L1K3 B1WCA1 B5DFI8 D3ZDK2 D3ZDN9 D3ZIT4 D3ZQX4 D3ZUB7 D3ZUW6 F1M3L4 F7EWF8 Q4V8A2 Q62623 Q6YDN7	Anapc1 Anapc15 Anapc16 Anapc2 Anapc4 Anapc5 Anapc7 Cdc14a Cdc16 Cdc20 Cdc23 Cdc26 Cdc27 Fzr1 LOC100366017 Ube2c Ube2d1 Ube2e1 Ube2s	Rattus norvegicus (Norway rat)

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