GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **101 - 125** of **1070** in total

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Pathway Name ▼	Protein Name	UniProt ID	Gene Symbol	Organism
TWIK-releated acid-sensitive K+ channel (TASK)	Potassium channel subfamily K member 3 Potassium channel subfamily K member 9	O54912 Q9ES08	Kcnk3 Kcnk9 Task Task1 Task3	Rattus norvegicus (Norway rat)
TWIK-related spinal cord K+ channel (TRESK)	Potassium channel subfamily K member 18	Q6Q1P3	Kcnk18 Tresk-2 Tresk2	Rattus norvegicus (Norway rat)
TWIK related potassium channel (TREK)	Potassium channel subfamily K member 10 Potassium channel subfamily K member 2 Potassium channel subfamily K member 4	G3V8V5 Q920B6 Q9JIS4	Kcnk10 Kcnk2 Kcnk4 Trek Trek2	Rattus norvegicus (Norway rat)
TRP channels	Mucolipin 2 Mucolipin TRP cation channel 1 Mucolipin TRP cation channel 3 Short transient receptor potential channel 1 Short transient receptor potential channel 3 Short transient receptor potential channel 4 Transient receptor potential cation channel subfamily A member 1 Transient receptor potential cation channel subfamily C member 5 Transient receptor potential cation channel subfamily M member 1 Transient receptor potential cation channel subfamily M member 2 Transient receptor potential cation channel subfamily M member 4 Transient receptor potential cation channel subfamily M member 7 Transient receptor potential cation channel subfamily M member 8 Transient receptor potential cation channel subfamily V member 1 Transient receptor potential cation channel subfamily V member 2 Transient receptor potential cation channel subfamily V member 4 Transient receptor potential cation channel subfamily V member 5 Transient receptor potential cation channel subfamily V member 6 Transient receptor potential cation channel, subfamily C, member 7 Transient receptor potential cation channel, subfamily M, member 3 Transient receptor potential cation channel, subfamily M, member 5 Transient receptor potential cation channel, subfamily V, member 3 non-specific serine/threonine protein kinase	A0A8I5ZXW7 A0A8I6ALW5 D3ZRF9 E9PTA2 E9PU00 F1LMD7 F1LQF7 F1M7G0 O35119 O35433 Q2WEA5 Q499S1 Q6RI86 Q8R455 Q8VD38 Q925B3 Q9ERZ8 Q9ESQ5 Q9JIP0 Q9JMI9 Q9QX01 Q9R186 Q9WUD2	Anktm1 Cat2 Cmr1 Ecac Ecac1 Ltrpc4 Mcoln1 Mcoln2 Mcoln3 Sac2b Trp1 Trpa1 Trpc1 Trpc3 Trpc4 Trpc5 Trpc7 Trpm1 Trpm2 Trpm3 Trpm4 Trpm5 Trpm6 Trpm7 Trpm8 Trpv1 Trpv2 Trpv3 Trpv4 Trpv5 Trpv6 Trrp3 Vr1 Vr1l Vrl1 Vroac	Rattus norvegicus (Norway rat)
TRKA activation by NGF	Beta-nerve growth factor High affinity nerve growth factor receptor	P25427 P35739	Ngf Ngfb Ntrk1 Trk Trka	Rattus norvegicus (Norway rat)
TRIF-mediated programmed cell death	Caspase-8 FAS-associated death domain protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor interacting serine/threonine kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain containing adaptor molecule 2 TIR domain-containing adapter molecule 1 Toll-like receptor 4	D3ZXR7 D3ZYL0 M0RA08 Q56DL5 Q63691 Q8R2E7 Q9JHX4 Q9QX05 Q9Z2P5	Casp8 Cd14 Fadd Ly96 Plin3 Rip3 Ripk1 Ripk3 Ticam1 Ticam2 Tlr4	Rattus norvegicus (Norway rat)
TRAF6-mediated induction of TAK1 complex within TLR4 complex	Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Mitogen-activated protein kinase kinase kinase 7 Monocyte differentiation antigen CD14 NAD(+) hydrolase SARM1 Polyubiquitin-B Polyubiquitin-C TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TGF-beta activated kinase 1/MAP3K7 binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TIR domain containing adaptor molecule 2 TIR domain-containing adapter molecule 1 TNF receptor-associated factor 6 Toll-like receptor 4 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0U1RRU5 A0A8I6A5Y3 A0A8I6ABN5 B5DF45 D3ZUM2 D3ZXR7 M0RA08 P0C8E4 P0CG51 P62982 Q4QQS0 Q56DL5 Q5U303 Q63429 Q63691 Q9QX05	Cd14 Irak2 LOC100360645 Ly96 Map3k7 Map3k7ip2 Plin3 Rps27a Sarm1 Tab1 Tab2 Tab3 Ticam1 Ticam2 Tlr4 Traf6 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Mitogen-activated protein kinase kinase kinase 1 TNF receptor-associated factor 6	B5DF45 Q5XIC2 Q62925	Ecsit Map3k1 Mekk Mekk1 Traf6	Rattus norvegicus (Norway rat)
TRAF6 mediated NF-kB activation	Advanced glycosylation end product-specific receptor Amyloid-beta precursor protein High mobility group protein B1 High mobility group protein B1 High mobility group protein B1 High mobility group protein B1 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator NF-kappa-B essential modulator NF-kappa-B inhibitor alpha NF-kappa-B inhibitor beta NF-kappa-B inhibitor-interacting Ras-like protein 2 NFKB inhibitor interacting Ras-like 1 Nuclear factor kappa B subunit 2 Protein S100-B RELA proto-oncogene, NF-kB subunit	A0A0G2K6P4 A0A8I5Y7D7 A0A8I5ZMV7 A0A8I6AH74 A0A8I6ANR6 A0A8I6APQ3 A0A8I6G6F3 A0A8I6GBU6 D3ZCK2 P04631 P08592 P63159 Q63495 Q63746 Q6TMG5 Q9JIA3 Q9QY78	A4 AD1 Ager App Chuk Hmg-1 Hmg1 Hmgb1 Hmgb1-ps33 Hmgb1-ps4 Hmgb1l1 Hmgb1l2 Hmgb1l3 Hmgb1l5 Ikba Ikbb Ikbkb Ikbkg Ikkb LOC108349189 LOC108350839 Nemo Nfkb2 Nfkbia Nfkbib Nkiras1 Nkiras2 Rage Rela S100b	Rattus norvegicus (Norway rat)
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	CCR4-NOT transcription complex subunit 10 CCR4-NOT transcription complex subunit 11 CCR4-NOT transcription complex subunit 6 CCR4-NOT transcription complex subunit 9 CCR4-NOT transcription complex, subunit 1 CCR4-NOT transcription complex, subunit 2 CCR4-NOT transcription complex, subunit 3 CCR4-NOT transcription complex, subunit 4 Centromere protein J M-phase inducer phosphatase Nucleophosmin Protein BTG2 Serine/threonine-protein kinase PLK2 Serine/threonine-protein kinase PLK3 Tankyrase 1 binding protein 1 poly(A)-specific ribonuclease	A0A8I6AJD1 A0A8I6AL98 B0BNA9 D3ZF26 D3ZUV9 D4A194 D4ADT2 G3V7M0 P13084 P27049 Q498M7 Q5PQL2 Q5XIA4 Q6AXU9 Q9R011 Q9R012	Btg2 Ccr4 Cdc25c Cenpj Cnk Cnot1 Cnot10 Cnot11 Cnot2 Cnot3 Cnot4 Cnot6 Cnot6l Cnot9 Fnk Npm1 Pc3 Plk2 Plk3 Rcd1 Rqcd1 Snk Tnks1bp1	Rattus norvegicus (Norway rat)
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	Apoptosis regulator BAX Aurora kinase A Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 Growth arrest and DNA damage-inducible protein GADD45 alpha Proliferating cell nuclear antigen Stratifin	G3V9A3 P04961 P30277 P39951 P48317 P59241 Q63690	Aik Airk1 Ark1 Aura Aurka Ayk1 Bax Btak Ccnb1 Cdc2 Cdc2a Cdk1 Cdkn1 Ddit1 Gadd45 Gadd45a Iak1 Pcna Sfn Stk15 Stk6	Rattus norvegicus (Norway rat)
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	Cyclin E2 Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase inhibitor 1A Cyclin-dependent kinase inhibitor 1B G1/S-specific cyclin-E1 Transcription factor E2F7 Transcription factor E2F8	A0A0G2JVY9 A0A8I5ZZ18 D3ZQ41 D4A4D7 F1LMN3 O08769 P39949 Q63699 Q6AY13	Ccna1 Ccna2 Ccne Ccne1 Ccne2 Cdk2 Cdkn1a Cdkn1b Cdkn2 E2f7 E2f8 p27Kip1	Rattus norvegicus (Norway rat)
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	BCL2 interacting protein 3 like Metalloreductase STEAP3 Serine-protein kinase ATM Zinc finger protein 420	A0A8I6AG85 D3Z901 D4ACL8 Q5RKL5	Atm Bnip3l Steap3 Zfp420	Rattus norvegicus (Norway rat)
TP53 Regulates Transcription of Death Receptors and Ligands	Insulin-like growth factor-binding protein 3 Transmembrane protein 219	A0A8I6AHK8 P15473	Igfbp-3 Igfbp3 Tmem219	Rattus norvegicus (Norway rat)
TP53 Regulates Metabolic Genes	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein theta 14-3-3 protein zeta/delta 5'-AMP-activated protein kinase catalytic subunit alpha-1 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 Cytochrome c domain-containing protein Cytochrome c oxidase assembly factor COX18 Cytochrome c oxidase assembly protein COX14 Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial Cytochrome c oxidase assembly protein COX20, mitochondrial Cytochrome c oxidase copper chaperone COX11 Cytochrome c oxidase subunit 1 Cytochrome c oxidase subunit 2 Cytochrome c oxidase subunit 3 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial Cytochrome c oxidase subunit 5A, mitochondrial Cytochrome c oxidase subunit 5B, mitochondrial Cytochrome c oxidase subunit 6A1, mitochondrial Cytochrome c oxidase subunit 6C-2 Cytochrome c oxidase subunit 7A2 like Cytochrome c oxidase subunit 7B, mitochondrial Cytochrome c oxidase subunit 7C, mitochondrial Cytochrome c oxidase subunit 8A, mitochondrial Cytochrome c oxidase subunit Cytochrome c, somatic DNA damage-inducible transcript 4 protein Fructose-2,6-bisphosphatase TIGAR GTP-binding protein Rheb Glucose-6-phosphate 1-dehydrogenase Glucose-6-phosphate isomerase Glutaminase kidney isoform, mitochondrial Glutaminase liver isoform, mitochondrial Glutathione peroxidase 2 Glutathione reductase (Fragment) Hamartin Leucine-rich PPR motif-containing protein, mitochondrial Neutral amino acid transporter 9 Peroxiredoxin-1 Peroxiredoxin-2 Peroxiredoxin-5, mitochondrial Protein kinase AMP-activated non-catalytic subunit gamma 2 Protein kinase AMP-activated non-catalytic subunit gamma 3 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein Ras-related GTP-binding protein Regulatory associated protein of MTOR, complex 1 Roadblock/LAMTOR2 domain-containing protein Serine/threonine-protein kinase mTOR Sestrin 1 Sestrin 2 Sestrin 3 Similar to Cytochrome c, somatic Stratifin Surfeit locus protein 1 Synthesis of cytochrome C oxidase 1 Target of rapamycin complex subunit LST8 Thioredoxin reductase 1, cytoplasmic Thioredoxin Thymidine phosphorylase Translational activator of cytochrome c oxidase 1 Tuberin	A0A0G2K4P1 A0A0G2K8S8 A0A140UHX4 A0A8I5ZSY5 A0A8I5ZWG1 A0A8I6A0N4 A0A8I6A8X0 A0A8I6AAY1 A0A8I6ADH7 B2GUV6 B2RYT9 B2RZ38 D3Z8B0 D3ZDU2 D3ZF11 D3ZNJ0 D3ZXV2 D4A568 D4A5L9 D4A7E4 D4AD29 G3V985 G3V9A3 O89049 P00406 P05370 P05503 P05505 P10818 P10888 P11232 P11240 P11951 P12075 P13264 P28492 P35213 P35704 P42346 P47196 P47197 P49816 P54645 P61983 P62260 P62898 P63102 P68255 P68511 P70619 P80385 P80386 P80431 P80432 P80433 P83645 Q0D2L6 Q3B8Q3 Q5SGE0 Q5U204 Q5XFV8 Q62639 Q63484 Q63486 Q63487 Q63716 Q6P6V0 Q6P791 Q8VHZ9 Q9QXU2 Q9QZH4 Q9R063 Q9Z136 Q9Z2K5	AC128290.1 Akt1 Akt2 Akt3 Ampk1 COX2 Ccdc44 Coi Coii Coiii Cox11 Cox14 Cox16 Cox18 Cox4 Cox4a Cox4i1 Cox5a Cox5b Cox6a1 Cox6al Cox6b1 Cox6c Cox6c2 Cox7a2l Cox7b Cox7c Cox7c1 Cox8 Cox8a Cox8l Cycs Cycsl2 Cycsl3 Ddit4 ENSRNOG00000066475 Frap1 G6pd G6pdx Ga Gbl Gls Gls2 Gpi Gpx2 Gsr LOC120096563 LOC690675 Lamtor1 Lamtor3 Lamtor4 Lamtor5 Lrp157 Lrpprc Lst8 Map2k1ip1 Mlst8 Msfs1 Mt-co1 Mt-co2 Mt-co3 Mtco1 Mtco2 Mtco3 Mtor Prdx1 Prdx2 Prdx5 Prkaa1 Prkab1 Prkab2 Prkag1 Prkag2 Prkag3 RGD1562558 Raft1 Redd1 Rheb Rptor RragB Rraga Rragc Rragc_predicted Rragd Rtp801 Sco1 Sesn1 Sesn2 Sesn3 Sfn Slc38a9 Surf-1 Surf1 Taco1 Tdpx1 Tdpx2 Tigar Trxr1 Tsc1 Tsc2 Txn Txn1 Txnrd1 Tymp Ywhab Ywhae Ywhag Ywhah Ywhaq Ywhaz	Rattus norvegicus (Norway rat)
TNFs bind their physiological receptors	EDAR-associated death domain Ectodysplasin A2 receptor Ectodysplasin-A receptor Ectodysplasin-A Lymphotoxin-alpha TNF receptor superfamily member 13B TNF receptor superfamily member 14 TNF receptor superfamily member 17 TNF receptor superfamily member 18 TNF receptor superfamily member 25 TNF receptor superfamily member 9 TNF superfamily member 13 TNF superfamily member 13b TNF superfamily member 18 TNF superfamily member 8 TNF superfamily member 9 Tumor necrosis factor ligand superfamily member 11 Tumor necrosis factor ligand superfamily member 15 Tumor necrosis factor ligand superfamily member 4 Tumor necrosis factor receptor superfamily member 11B Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor superfamily member 1B Tumor necrosis factor receptor superfamily member 4 Tumor necrosis factor receptor superfamily member 8	A0A096MIW0 A0A096MJP5 A0A8I6ATG2 A0A8J8XC20 D3ZFD8 D3ZGP2 D3ZKQ8 D4A3I1 D4ADP7 F1LX35 F1LYE0 F7FFS7 M0R3V3 O08727 P15725 P22934 P97525 Q06332 Q4V895 Q80WE6 Q80WY6 Q8K3Y7 Q9ESE2 Q9Z2P3	Cd30 Eda Eda2r Edar Edaradd Lta Opg Opgl Ox40 Ox40l Rankl Tl1 Tnfb Tnfr-1 Tnfr1 Tnfr2 Tnfrsf11b Tnfrsf13b Tnfrsf14 Tnfrsf17 Tnfrsf18 Tnfrsf1a Tnfrsf1b Tnfrsf25 Tnfrsf4 Tnfrsf8 Tnfrsf9 Tnfsf1 Tnfsf11 Tnfsf13 Tnfsf13b Tnfsf15 Tnfsf18 Tnfsf4 Tnfsf8 Tnfsf9 Tnlg3a Tnlg5a Trance Txgp1 Txgp1l Vegi	Rattus norvegicus (Norway rat)
TNFR2 non-canonical NF-kB pathway	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Baculoviral IAP repeat-containing 2 Baculoviral IAP repeat-containing 3 CD40 ligand Lymphotoxin beta receptor Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta TNF receptor superfamily member 11A TNF receptor superfamily member 12A TNF receptor superfamily member 13C TNF receptor-associated factor TNF receptor-associated factor TNF superfamily member 12 TNF superfamily member 13b TNF superfamily member 14 Tumor necrosis factor ligand superfamily member 11 Tumor necrosis factor receptor superfamily member 1B Tumor necrosis factor receptor superfamily member 5 Tumor necrosis factor	A0A0G2JSL0 A0A0G2JTI9 A0A0G2K7X2 A0A0G2KAX0 A0A0U5J4Y0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I6AHI1 A0A8I6GJT5 B0BN93 B5DFH7 D3ZFD8 D3ZTD1 D4A281 F1LMQ3 F1LMZ8 F1M6I7 F1M8Z6 F7FGV7 G3V6F9 G3V6W6 G3V8G2 M0RCN2 O88761 P16599 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 Q06332 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63569 Q63570 Q63797 Q63798 Q6MG45 Q6P6S1 Q80WY6 Q9ESE2 Q9JHW0 Q9WTV5 Q9Z2V2 Q9Z2X3	Birc2 Birc3 Cd40 Cd40l Cd40lg LOC100360846 LOC100365869 Lmp10 Lmp2 Lta Ltb Ltbr Map3k14 Mecl1 Mss1 Opgl Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Rankl Ring12 Sug1 Tbp1 Tbp7 Tnf Tnfa Tnfb Tnfr2 Tnfrsf11a Tnfrsf12a Tnfrsf13c Tnfrsf1b Tnfsf1 Tnfsf11 Tnfsf12 Tnfsf13b Tnfsf14 Tnfsf2 Tnfsf5 Tnlg1d Tnlg4a Traf2 Traf3 Trance	Rattus norvegicus (Norway rat)
TNFR1-mediated ceramide production	Neutral sphingomyelinase activation associated factor Small ribosomal subunit protein RACK1 Sphingomyelin phosphodiesterase 2 Sphingomyelin phosphodiesterase 3 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor	F1M974 O35049 P16599 P22934 P63245 Q9ET64	Cca1 Gnb2l1 Nsmaf Rack1 Smpd2 Smpd3 Tnf Tnfa Tnfr-1 Tnfr1 Tnfrsf1a Tnfsf2	Rattus norvegicus (Norway rat)
TNFR1-induced proapoptotic signaling	Baculoviral IAP repeat-containing 2 Baculoviral IAP repeat-containing 3 E3 ubiquitin-protein ligase MIB2 E3 ubiquitin-protein ligase XIAP FAS-associated death domain protein Inhibitor of nuclear factor kappa B kinase subunit epsilon RBR-type E3 ubiquitin transferase RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor interacting serine/threonine kinase 1 Spermatogenesis-associated protein 2 TANK-binding kinase 1 TNF receptor-associated factor Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin carboxyl-terminal hydrolase 21 Ubiquitin carboxyl-terminal hydrolase 2 Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase CYLD ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A0G2JTI9 A0A0G2K5N0 A0A8I6AL23 B2GUX4 B2GUZ1 B5DFH7 D3ZNC0 D3ZYL0 D3ZZC5 D4A5E7 D4A7D3 E9PU29 P16599 P22934 Q5U349 Q62921 Q66H62 Q66HP6 Q68LP1 Q6P6S1 Q8R2E7 Q9R0I6	Api3 Birc2 Birc3 Birc4 Cyld Cyld1 Fadd Ikbke Mib2 Otud1 Otud7b Pd1 Pkcbpb15 Rbck Rbck1 Ripk1 Rnf31 Spata2 Tbk1 Tnf Tnfa Tnfaip3 Tnfr-1 Tnfr1 Tnfrsf1a Tnfsf2 Tradd Traf2 Ubce7ip3 Ubp41 Ubp69 Usp2 Usp21 Usp4 Xiap	Rattus norvegicus (Norway rat)
TNFR1-induced NF-kappa-B signaling pathway	Baculoviral IAP repeat-containing 2 Baculoviral IAP repeat-containing 3 E3 ubiquitin-protein ligase XIAP Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator NF-kappa-B essential modulator Optineurin RBR-type E3 ubiquitin transferase RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor interacting serine/threonine kinase 1 Small ribosomal subunit protein RACK1 Spermatogenesis-associated protein 2 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TGF-beta activated kinase 1/MAP3K7 binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TNF receptor-associated factor TNF receptor-associated factor Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin carboxyl-terminal hydrolase 21 Ubiquitin carboxyl-terminal hydrolase 2 Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase CYLD ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A0G2JTI9 A0A0G2K5N0 A0A0U1RRU5 A0A1B0GWY7 A0A8I6ABN5 A0A8I6AH74 A0A8I6AL23 A0A8I6ANR6 B2GUX4 B2GUZ1 B5DFH7 D3ZNC0 D3ZYL0 D3ZZC5 E9PU29 P0C8E4 P16599 P22934 P63245 Q5U303 Q5U349 Q62921 Q66H62 Q66HP6 Q6P6S1 Q6TMG5 Q8R5M4 Q9QY78 Q9R0I6	Api3 Birc2 Birc3 Birc4 Chuk Cyld Cyld1 Gnb2l1 Ikbkb Ikbkg Ikkb Map3k7 Map3k7ip2 Nemo Optn Otud1 Otud7b Pd1 Pkcbpb15 Rack1 Rbck Rbck1 Ripk1 Rnf31 Spata2 Tab1 Tab2 Tab3 Tnf Tnfa Tnfaip3 Tnfr-1 Tnfr1 Tnfrsf1a Tnfsf2 Tradd Traf1 Traf2 Ubce7ip3 Ubp41 Ubp69 Usp2 Usp21 Usp4 Xiap	Rattus norvegicus (Norway rat)
TNF signaling	BAG cochaperone 4 Disintegrin and metalloproteinase domain-containing protein 17 Receptor interacting serine/threonine kinase 1 TNF receptor-associated factor Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor	A0A8I6AP78 B5DFH7 D3ZYL0 D3ZZC5 P16599 P22934 Q9Z1K9	Adam17 Bag4 Ripk1 Tace Tnf Tnfa Tnfr-1 Tnfr1 Tnfrsf1a Tnfsf2 Tradd Traf2	Rattus norvegicus (Norway rat)
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	Baculoviral IAP repeat-containing 2 Baculoviral IAP repeat-containing 3 CD40 ligand Lymphotoxin beta receptor Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 TNF receptor superfamily member 11A TNF receptor superfamily member 12A TNF receptor superfamily member 13C TNF receptor-associated factor TNF receptor-associated factor TNF superfamily member 12 TNF superfamily member 13b TNF superfamily member 14 Tumor necrosis factor ligand superfamily member 11 Tumor necrosis factor receptor superfamily member 5	A0A0G2JTI9 A0A0G2K7X2 A0A0U5J4Y0 A0A8I6AHI1 A0A8I6GJT5 B5DFH7 D3ZFD8 D3ZTD1 D4A281 F1M8Z6 G3V6F9 M0RCN2 Q06332 Q6MG45 Q6P6S1 Q9ESE2 Q9Z2V2	Birc2 Birc3 Cd40 Cd40l Cd40lg Lta Ltb Ltbr Map3k14 Opgl Rankl Tnfb Tnfrsf11a Tnfrsf12a Tnfrsf13c Tnfsf1 Tnfsf11 Tnfsf12 Tnfsf13b Tnfsf14 Tnfsf5 Tnlg1d Tnlg4a Traf2 Traf3 Trance	Rattus norvegicus (Norway rat)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	Cingulin E3 ubiquitin-protein ligase Junctional adhesion molecule A Partitioning defective 3 homolog Partitioning defective 6 homolog alpha Polyubiquitin-B Polyubiquitin-C Protein kinase C zeta type TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein Transforming protein RhoA Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2K612 A0A8I6A4L9 A0A8I6A5Y3 P09217 P0CG51 P17246 P38438 P61589 P62982 P80204 Q63429 Q6B4M5 Q9JHY1 Q9Z340	Arha Arha2 Cgn F11r Jam1 LOC100360645 Par-6a Par3 Par6a Pard3 Pard6a Pkcz Prkcz Rhoa Rps27a Smurf1 Tgfb1 Tgfbr1 Tgfbr2 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
TGF-beta receptor signaling activates SMADs	E3 ubiquitin-protein ligase CBL Furin Integrin beta-1 Integrin beta-3 Integrin beta-6 Integrin beta Integrin beta Integrin subunit alpha 8 Integrin subunit alpha V Latent transforming growth factor beta binding protein 3 Latent transforming growth factor beta binding protein 4 Latent-transforming growth factor beta-binding protein 1 Latent-transforming growth factor beta-binding protein 2 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 NEDD8 Peptidyl-prolyl cis-trans isomerase FKBP1A TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta receptor type 3 Transforming growth factor beta-1 proprotein Transforming growth factor beta-2 proprotein Transforming growth factor beta-3 proprotein Ubiquitin-conjugating enzyme E2M Zinc finger FYVE domain-containing protein	A0A0G2JVU1 A0A8I5ZYZ8 A0A8I6AQL1 A0A8I6AVC5 A0A8I6G3R2 D3ZDC7 D4A917 F1LZX9 F7F1E3 O35806 O70436 O70437 P17246 P23377 P26342 P38438 P49134 P80204 P84025 Q00918 Q07257 Q07258 Q62658 Q6AYF4 Q71UE8 Q8R2H2	Cbl Fkbp1 Fkbp1a Fur Furin Itga8 Itgav Itgb1 Itgb3 Itgb5 Itgb6 Itgb8 Ltbp1 Ltbp2 Ltbp3 Ltbp4 Madh2 Madh3 Madh4 Nedd8 Pcsk3 Smad2 Smad3 Smad4 Tgf-b3 Tgfb1 Tgfb2 Tgfb3 Tgfbr1 Tgfbr2 Tgfbr3 Ube2m Zfyve9	Rattus norvegicus (Norway rat)
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	ATPase family, AAA domain containing 2 Estrogen receptor Glycoprotein hormones alpha chain Lutropin subunit beta	A0A8I5ZNS1 P01230 P06211 P11962	Atad2 Cga Cga1 Esr Esr1 Estr Lhb Nr3a1	Rattus norvegicus (Norway rat)

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