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Standards Ontologies Notations
cholestasis

Summary
Synonym
  • Obstruction of bile duct
  • bile occlusion
Definition
A bile duct disease that is characterized by where bile cannot flow from the liver to the duodenum.
Super Class
bile duct disease
Disease Ontology
DOID:13580
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 21 - 30 of 44 in total
Gene ID Gene Symbol Description Source
3565 IL4 interleukin 4
3920 LAMP2 lysosomal associated membrane protein 2
4313 MMP2 matrix metallopeptidase 2
4846 NOS3 nitric oxide synthase 3
5155 PDGFB platelet derived growth factor subunit B
5243 ABCB1 ATP binding cassette subfamily B member 1
5244 ABCB4 ATP binding cassette subfamily B member 4
5562 PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1
5837 PYGM glycogen phosphorylase, muscle associated
6554 SLC10A1 solute carrier family 10 member 1
Displaying entries 21 - 30 of 35 in total
Gene ID Gene Symbol Description Source
18670 Abcb4 ATP-binding cassette, sub-family B member 4
19309 Pygm muscle glycogen phosphorylase
20493 Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1
21857 Timp1 tissue inhibitor of metalloproteinase 1
21872 Tjp1 tight junction protein 1
27409 Abcg5 ATP binding cassette subfamily G member 5
27413 Abcb11 ATP-binding cassette, sub-family B member 11
28250 Slco1a4 solute carrier organic anion transporter family, member 1a4
28253 Slco1b2 solute carrier organic anion transporter family, member 1b2
67470 Abcg8 ATP binding cassette subfamily G member 8
Displaying entries 11 - 20 of 24 in total
Gene ID Gene Symbol Description Source
25303 Abcc2 ATP binding cassette subfamily C member 2
25406 Cd44 CD44 molecule
29393 Col1a1 collagen type I alpha 1 chain
58978 Slco1b2 solute carrier organic anion transporter family member 1B2
60350 Cd14 CD14 molecule
65248 Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1
81686 Mmp2 matrix metallopeptidase 2
83569 Abcb11 ATP binding cassette subfamily B member 11
114628 Abcg5 ATP binding cassette subfamily G member 5
116510 Timp1 TIMP metallopeptidase inhibitor 1
Displaying all 8 entries
Gene ID Gene Symbol Description Source
32974 Zw Zwischenferment
33386 Glyp Glycogen phosphorylase
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
36428 Mdr49 Multi drug resistance 49
38726 Mdr65 Multi drug resistance 65
39954 Oatp74D Organic anion transporting polypeptide 74D
47905 l(2)03659 lethal (2) 03659
Displaying all 2 entries
Gene ID Gene Symbol Description Source
559080 cftr CF transmembrane conductance regulator
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Displaying 1 entry
Gene ID Gene Symbol Description Source Organism
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 13 in total
Gene ID Gene Symbol Description Source
175383 zmp-2 Matrix metalloproteinase-B
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
178215 pgp-1 Multidrug resistance protein pgp-1
179197 cri-2 Putative metalloproteinase inhibitor tag-225
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180289 mrp-7 Multidrug resistance protein mrp-7
180351 W01F3.2 Uncharacterized protein
180408 mrp-2 Multidrug resistance-associated protein 1
180409 mrp-1 Multidrug resistance-associated protein 1
180780 acn-1 Inactive angiotensin-converting enzyme-related protein
Displaying all 6 entries
Gene ID Gene Symbol Description Source
850645 BPT1 ATP-binding cassette bilirubin transporter BPT1
853671 STE6 ATP-binding cassette a-factor transporter STE6
853978 NFT1 putative multidrug transporter NFT1
854080 YOL075C uncharacterized protein
855480 ZWF1 glucose-6-phosphate dehydrogenase
856289 GPH1 glycogen phosphorylase
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024