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Standards Ontologies Notations
Parkinson's disease

Summary
Synonym
  • Parkinson disease
  • paralysis agitans
Definition
A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.
Super Class
synucleinopathy
External Links
Disease Ontology
DOID:14330
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
OMIM
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 11 - 20 of 180 in total
Gene ID Gene Symbol Description Source
208 AKT2 AKT serine/threonine kinase 2
308 ANXA5 annexin A5
335 APOA1 apolipoprotein A1
348 APOE apolipoprotein E
355 FAS Fas cell surface death receptor
356 FASLG Fas ligand
472 ATM ATM serine/threonine kinase
567 B2M beta-2-microglobulin
627 BDNF brain derived neurotrophic factor
811 CALR calreticulin
Displaying entries 51 - 60 of 146 in total
Gene ID Gene Symbol Description Source
16337 Insr insulin receptor
16846 Lep leptin
17762 Mapt microtubule-associated protein tau
18039 Nefl neurofilament, light polypeptide
18053 Ngfr nerve growth factor receptor (TNFR superfamily, member 16)
18174 Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
18195 Nsf N-ethylmaleimide sensitive fusion protein
18216 Ntsr1 neurotensin receptor 1
18294 Ogg1 8-oxoguanine DNA-glycosylase 1
18386 Oprd1 opioid receptor, delta 1
Displaying entries 1 - 10 of 82 in total
Gene ID Gene Symbol Description Source
24153 A2m alpha-2-macroglobulin
24180 Agtr1a angiotensin II receptor, type 1a
24185 Akt1 AKT serine/threonine kinase 1
24225 Bdnf brain-derived neurotrophic factor
24296 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
24318 Drd2 dopamine receptor D2
24335 Epo erythropoietin
24473 Htr1a 5-hydroxytryptamine receptor 1A
24483 Igf2 insulin-like growth factor 2
24596 Ngfr nerve growth factor receptor
Displaying entries 1 - 10 of 25 in total
Gene ID Gene Symbol Description Source
31248 sgg shaggy
31399 Torsin torsin
31718 Tbh Tyramine beta hydroxylase
31806 Ogg1 8-oxoguanine DNA glycosylase
33007 Dop2R Dopamine 2-like receptor
33461 Pgk Phosphoglycerate kinase
35851 ptc patched
35886 Pgi Phosphoglucose isomerase
36232 Sod3 Superoxide dismutase 3
37191 5-HT1B 5-hydroxytryptamine (serotonin) receptor 1B
Displaying all 9 entries
Gene ID Gene Symbol Description Source
114549 ache acetylcholinesterase (Yt blood group)
436629 nus1 NUS1 dehydrodolichyl diphosphate synthase subunit
437021 tspan36 tetraspanin 36
494492 slc17a6a solute carrier family 17 member 6a
560788 parp1 poly (ADP-ribose) polymerase 1
563467 slc17a8 solute carrier family 17 member 8
768121 foxo1a forkhead box O1 a
100004455 epoa erythropoietin a
100149756 slc17a6b solute carrier family 17 member 6b
Displaying all 7 entries
Gene ID Gene Symbol Description Source Organism
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
398763 agtr1.L angiotensin II receptor type 1 L homeolog Xenopus laevis (African clawed frog)
399170 akt1.S AKT serine/threonine kinase 1 S homeolog Xenopus laevis (African clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
108705891 drd5.S dopamine receptor D5 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 21 - 26 of 26 in total
Gene ID Gene Symbol Description Source
180939 smf-1 NRAMP-like transporter smf-1
181639 tbh-1 DOMON domain-containing protein;Tyramine beta-hydroxylase
181706 ace-1 Acetylcholinesterase 1
183155 gba-2 Putative glucosylceramidase 2
191766 smf-2 NRAMP-like transporter smf-2
266823 parp-1 Poly [ADP-ribose] polymerase;Poly [ADP-ribose] polymerase 1
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
850370 PGK1 phosphoglycerate kinase
850721 SMF3 putative divalent metal ion transporter SMF3
851013 ACO1 aconitate hydratase ACO1
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
852351 AKL1 serine/threonine protein kinase AKL1
852470 SMY2 Smy2p
852495 PGI1 glucose-6-phosphate isomerase
852806 HSF1 stress-responsive transcription factor HSF1
853071 TIF4631 translation initiation factor eIF4G
853300 YAK1 serine/threonine protein kinase YAK1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024