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Standards Ontologies Notations
Parkinson's disease

Summary
Synonym
  • Parkinson disease
  • paralysis agitans
Definition
A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.
Super Class
synucleinopathy
External Links
Disease Ontology
DOID:14330
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
OMIM
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 180 in total
Gene ID Gene Symbol Description Source
2 A2M alpha-2-macroglobulin
25 ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
43 ACHE acetylcholinesterase (Yt blood group)
50 ACO2 aconitase 2
111 ADCY5 adenylate cyclase 5
131 ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
142 PARP1 poly(ADP-ribose) polymerase 1
157 GRK3 G protein-coupled receptor kinase 3
185 AGTR1 angiotensin II receptor type 1
207 AKT1 AKT serine/threonine kinase 1
Displaying entries 51 - 60 of 146 in total
Gene ID Gene Symbol Description Source
16337 Insr insulin receptor
16846 Lep leptin
17762 Mapt microtubule-associated protein tau
18039 Nefl neurofilament, light polypeptide
18053 Ngfr nerve growth factor receptor (TNFR superfamily, member 16)
18174 Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
18195 Nsf N-ethylmaleimide sensitive fusion protein
18216 Ntsr1 neurotensin receptor 1
18294 Ogg1 8-oxoguanine DNA-glycosylase 1
18386 Oprd1 opioid receptor, delta 1
Displaying entries 31 - 40 of 82 in total
Gene ID Gene Symbol Description Source
25715 Slc11a2 solute carrier family 11 member 2
25718 Igf1r insulin-like growth factor 1 receptor
26201 ND4 NADH dehydrogenase subunit 4
29143 Grn granulin precursor
29219 Snca synuclein alpha
29237 Penk proenkephalin
29238 Drd3 dopamine receptor D3
29256 Oprl1 opioid related nociceptin receptor 1
29335 Oprk1 opioid receptor, kappa 1
29414 Akt3 AKT serine/threonine kinase 3
Displaying entries 1 - 10 of 25 in total
Gene ID Gene Symbol Description Source
31248 sgg shaggy
31399 Torsin torsin
31718 Tbh Tyramine beta hydroxylase
31806 Ogg1 8-oxoguanine DNA glycosylase
33007 Dop2R Dopamine 2-like receptor
33461 Pgk Phosphoglycerate kinase
35851 ptc patched
35886 Pgi Phosphoglucose isomerase
36232 Sod3 Superoxide dismutase 3
37191 5-HT1B 5-hydroxytryptamine (serotonin) receptor 1B
Displaying all 9 entries
Gene ID Gene Symbol Description Source
114549 ache acetylcholinesterase (Yt blood group)
436629 nus1 NUS1 dehydrodolichyl diphosphate synthase subunit
437021 tspan36 tetraspanin 36
494492 slc17a6a solute carrier family 17 member 6a
560788 parp1 poly (ADP-ribose) polymerase 1
563467 slc17a8 solute carrier family 17 member 8
768121 foxo1a forkhead box O1 a
100004455 epoa erythropoietin a
100149756 slc17a6b solute carrier family 17 member 6b
Displaying all 7 entries
Gene ID Gene Symbol Description Source Organism
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
398763 agtr1.L angiotensin II receptor type 1 L homeolog Xenopus laevis (African clawed frog)
399170 akt1.S AKT serine/threonine kinase 1 S homeolog Xenopus laevis (African clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
108705891 drd5.S dopamine receptor D5 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 26 in total
Gene ID Gene Symbol Description Source
171965 pgk-1 putative phosphoglycerate kinase
172105 unc-38 Acetylcholine receptor subunit alpha-type unc-38
172150 unc-63 Acetylcholine receptor subunit alpha-type unc-63
173574 gba-1 Putative glucosylceramidase 1
174274 ptc-1 Protein patched homolog 1;SSD domain-containing protein
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175076 ace-3 Carboxylic ester hydrolase
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176291 eat-4 Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
850370 PGK1 phosphoglycerate kinase
850721 SMF3 putative divalent metal ion transporter SMF3
851013 ACO1 aconitate hydratase ACO1
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
852351 AKL1 serine/threonine protein kinase AKL1
852470 SMY2 Smy2p
852495 PGI1 glucose-6-phosphate isomerase
852806 HSF1 stress-responsive transcription factor HSF1
853071 TIF4631 translation initiation factor eIF4G
853300 YAK1 serine/threonine protein kinase YAK1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024