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Standards Ontologies Notations
multiple sclerosis

Summary
Synonym
  • Generalized multiple sclerosis
  • insular sclerosis
Definition
A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.
Super Class
autoimmune disease of central nervous system demyelinating disease
Disease Ontology
DOID:2377
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 87 in total
Gene ID Gene Symbol Description Source
2 A2M alpha-2-macroglobulin
43 ACHE acetylcholinesterase (Yt blood group)
176 ACAN aggrecan
177 AGER advanced glycosylation end-product specific receptor
182 JAG1 jagged canonical Notch ligand 1
183 AGT angiotensinogen
335 APOA1 apolipoprotein A1
344 APOC2 apolipoprotein C2
355 FAS Fas cell surface death receptor
356 FASLG Fas ligand
Displaying entries 71 - 72 of 72 in total
Gene ID Gene Symbol Description Source
433759 Hdac1 histone deacetylase 1
100504404 H2-Ea histocompatibility 2, class II antigen E alpha
Displaying entries 31 - 40 of 43 in total
Gene ID Gene Symbol Description Source
83613 Nefl neurofilament light chain
83817 Ache acetylcholinesterase
116553 Il13 interleukin 13
117029 Ccr5 C-C motif chemokine receptor 5
117033 Mmp12 matrix metallopeptidase 12
246097 Fas Fas cell surface death receptor
287287 Il4 interleukin 4
287561 Ccl7 C-C motif chemokine ligand 7
289218 Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2
301252 Hsp90ab1 heat shock protein 90 alpha family class B member 1
Displaying all 10 entries
Gene ID Gene Symbol Description Source
32158 cac cacophony
36585 beta4GalNAcTA beta1,4-N-acetylgalactosaminyltransferase A
39443 Ptp69D Protein tyrosine phosphatase 69D
39984 Grd Glycine receptor
41625 Ace Acetylcholine esterase
41840 Hsc70-4 Heat shock protein 70 cognate 4
42490 Mvl Malvolio
43222 Tl Toll
43275 Ser Serrate
43425 beta4GalNAcTB beta1,4-N-acetylgalactosaminyltransferase B
Displaying all 8 entries
Gene ID Gene Symbol Description Source
114549 ache acetylcholinesterase (Yt blood group)
140421 jag1a jagged canonical Notch ligand 1a
393912 b4galt6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
406411 rhoaa ras homolog gene family, member Aa
406659 rhoac ras homolog gene family, member Ac
555941 cacna1ba calcium channel, voltage-dependent, N type, alpha 1B subunit, a
724080 b4galt5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
100006041 rhoab ras homolog gene family, member Ab
Displaying all 6 entries
Gene ID Gene Symbol Description Source Organism
446703 b4galt5.L UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 L homeolog Xenopus laevis (African clawed frog)
548965 b4galt6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 Xenopus tropicalis (tropical clawed frog)
549139 b4galt5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 Xenopus tropicalis (tropical clawed frog)
779435 b4galt6.L UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 L homeolog Xenopus laevis (African clawed frog)
108695277 b4galt6.S UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 S homeolog Xenopus laevis (African clawed frog)
108702589 b4galt5.S UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 11 - 20 of 20 in total
Gene ID Gene Symbol Description Source
180351 W01F3.2 Uncharacterized protein
180638 wrt-6 Warthog protein 6 N-product
180931 cpr-6 Cathepsin B-like cysteine proteinase 6
180939 smf-1 NRAMP-like transporter smf-1
181706 ace-1 Acetylcholinesterase 1
190602 drag-1 Repulsive guidance molecule B homolog drag-1
190668 bre-4 Beta-1,4-N-acetylgalactosaminyltransferase bre-4
191707 mgl-1 G-protein coupled receptors family 3 profile domain-containing protein;putative metabotropic glutamate receptor mgl-1
191766 smf-2 NRAMP-like transporter smf-2
3565419 clr-1 Receptor-type tyrosine-protein phosphatase;protein-tyrosine-phosphatase
Displaying all 2 entries
Gene ID Gene Symbol Description Source
850721 SMF3 putative divalent metal ion transporter SMF3
856294 RHO1 Rho family GTPase RHO1
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024