multiple sclerosis

Summary
Synonym
  • Generalized multiple sclerosis
  • insular sclerosis
Definition
A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.
Super Class
autoimmune disease of central nervous system demyelinating disease
Disease Ontology
DOID:2377
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 51 - 55 of 55 in total
Gene ID Gene Symbol Description Source
23274 CLEC16A C-type lectin domain containing 16A
50615 IL21R interleukin 21 receptor
56963 RGMA repulsive guidance molecule BMP co-receptor a
149233 IL23R interleukin 23 receptor
100133941 CD24 CD24 molecule
Displaying all 2 entries
Gene ID Gene Symbol Description Source
18646 Prf1 perforin 1 (pore forming protein)
21926 Tnf tumor necrosis factor

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 8, 2025