pulmonary fibrosis

Summary
Synonym
  • Fibrosis of lung
Definition
An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation.
Super Class
interstitial lung disease
Disease Ontology
DOID:3770
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 21 - 30 of 69 in total
Gene ID Gene Symbol Description Source
1672 DEFB1 defensin beta 1
1906 EDN1 endothelin 1
1956 EGFR epidermal growth factor receptor
1958 EGR1 early growth response 1
1991 ELANE elastase, neutrophil expressed
3026 HABP2 hyaluronan binding protein 2
3082 HGF hepatocyte growth factor
3326 HSP90AB1 heat shock protein 90 alpha family class B member 1
3329 HSPD1 heat shock protein family D (Hsp60) member 1
3383 ICAM1 intercellular adhesion molecule 1
Displaying entries 1 - 10 of 56 in total
Gene ID Gene Symbol Description Source
11421 Ace angiotensin I converting enzyme
11596 Ager advanced glycosylation end product-specific receptor
11774 Ap3b1 adaptor-related protein complex 3, beta 1 subunit
12015 Bad BCL2-associated agonist of cell death
12061 Bdkrb1 bradykinin receptor, beta 1
12064 Bdnf brain derived neurotrophic factor
12491 Cd36 CD36 molecule
12550 Cdh1 cadherin 1
12654 Chi3l1 chitinase 3 like 1
12671 Chrm3 cholinergic receptor, muscarinic 3, cardiac
Displaying entries 1 - 10 of 42 in total
Gene ID Gene Symbol Description Source
24179 Agt angiotensinogen
24225 Bdnf brain-derived neurotrophic factor
24260 Chrm3 cholinergic receptor, muscarinic 3
24310 Ace angiotensin I converting enzyme
24446 Hgf hepatocyte growth factor
24484 Igfbp3 insulin-like growth factor binding protein 3
24493 Il1a interleukin 1 alpha
24617 Serpine1 serpin family E member 1
24770 Ccl2 C-C motif chemokine ligand 2
24773 Sftpa1 surfactant protein A1
Displaying entries 11 - 16 of 16 in total
Gene ID Gene Symbol Description Source
37455 Egfr Epidermal growth factor receptor
37892 mAChR-A muscarinic Acetylcholine Receptor, A-type
38868 Snmp2 Sensory neuron membrane protein 2
42514 Snmp1 Sensory neuron membrane protein 1
43275 Ser Serrate
251900 GlcAT-I Glucuronyltransferase I
Displaying all 8 entries
Gene ID Gene Symbol Description Source
30718 notch1a notch receptor 1a
58133 ngfb nerve growth factor b (beta polypeptide)
114424 cdh1 cadherin 1, type 1, E-cadherin (epithelial)
140421 jag1a jagged canonical Notch ligand 1a
386856 pdgfra platelet-derived growth factor receptor, alpha polypeptide
548607 b3gat1a beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
100332644 b3gat1b beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) b
Displaying all 6 entries
Gene ID Gene Symbol Description Source Organism
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
100037842 notch1 notch 1 receptor Xenopus tropicalis (tropical clawed frog)
100037907 b3gat1 beta-1,3-glucuronyltransferase 1 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100337618 cdh1.S cadherin 1, type 1 S homeolog Xenopus laevis (African clawed frog)
108709389 ngf.S nerve growth factor S homeolog Xenopus laevis (African clawed frog)
Displaying entries 11 - 15 of 15 in total
Gene ID Gene Symbol Description Source
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
180628 cht-1 putative endochitinase
180780 acn-1 Inactive angiotensin-converting enzyme-related protein
180812 scav-1 SCAVenger receptor (CD36 family) related
Displaying all 2 entries
Gene ID Gene Symbol Description Source
851977 CTS2 putative chitinase
853177 APL6 Apl6p

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