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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
pulmonary fibrosis
Summary
- Synonym
-
- Fibrosis of lung
- Definition
- An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation.
- Super Class
- interstitial lung disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 6347 | CCL2 | C-C motif chemokine ligand 2 | |
| 6356 | CCL11 | C-C motif chemokine ligand 11 | |
| 6439 | SFTPB | surfactant protein B | |
| 6440 | SFTPC | surfactant protein C | |
| 6772 | STAT1 | signal transducer and activator of transcription 1 | |
| 7035 | TFPI | tissue factor pathway inhibitor | |
| 7040 | TGFB1 | transforming growth factor beta 1 | |
| 7048 | TGFBR2 | transforming growth factor beta receptor 2 | |
| 7076 | TIMP1 | TIMP metallopeptidase inhibitor 1 | |
| 7124 | TNF | tumor necrosis factor |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 16449 | Jag1 | jagged 1 | |
| 17128 | Smad4 | SMAD family member 4 | |
| 17195 | Mbl2 | mannose-binding lectin (protein C) 2 | |
| 17395 | Mmp9 | matrix metallopeptidase 9 | |
| 17833 | Muc5ac | mucin 5, subtypes A and C, tracheobronchial/gastric | |
| 18024 | Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | |
| 18049 | Ngf | nerve growth factor | |
| 18128 | Notch1 | notch 1 | |
| 18595 | Pdgfra | platelet derived growth factor receptor, alpha polypeptide | |
| 19225 | Ptgs2 | prostaglandin-endoperoxide synthase 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24179 | Agt | angiotensinogen | |
| 24225 | Bdnf | brain-derived neurotrophic factor | |
| 24260 | Chrm3 | cholinergic receptor, muscarinic 3 | |
| 24310 | Ace | angiotensin I converting enzyme | |
| 24446 | Hgf | hepatocyte growth factor | |
| 24484 | Igfbp3 | insulin-like growth factor binding protein 3 | |
| 24493 | Il1a | interleukin 1 alpha | |
| 24617 | Serpine1 | serpin family E member 1 | |
| 24770 | Ccl2 | C-C motif chemokine ligand 2 | |
| 24773 | Sftpa1 | surfactant protein A1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31293 | N | Notch | |
| 31926 | Idgf4 | Imaginal disc growth factor 4 | |
| 34189 | Acer | Angiotensin-converting enzyme-related | |
| 34282 | GlcAT-S | Glucuronyltransferase S | |
| 34805 | Ance | Angiotensin converting enzyme | |
| 34978 | Idgf1 | Imaginal disc growth factor 1 | |
| 34979 | Idgf2 | Imaginal disc growth factor 2 | |
| 34981 | Idgf3 | Imaginal disc growth factor 3 | |
| 36868 | Idgf6 | Imaginal disc growth factor 6 | |
| 37104 | Idgf5 | Imaginal disc growth factor 5 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30718 | notch1a | notch receptor 1a | |
| 58133 | ngfb | nerve growth factor b (beta polypeptide) | |
| 114424 | cdh1 | cadherin 1, type 1, E-cadherin (epithelial) | |
| 140421 | jag1a | jagged canonical Notch ligand 1a | |
| 386856 | pdgfra | platelet-derived growth factor receptor, alpha polypeptide | |
| 548607 | b3gat1a | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a | |
| 565980 | ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | |
| 100332644 | b3gat1b | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) b |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 397778 | tgfb1.L | transforming growth factor beta 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 100037842 | notch1 | notch 1 receptor | Xenopus tropicalis (tropical clawed frog) | |
| 100037907 | b3gat1 | beta-1,3-glucuronyltransferase 1 | Xenopus tropicalis (tropical clawed frog) | |
| 100144634 | ace | angiotensin I converting enzyme | Xenopus tropicalis (tropical clawed frog) | |
| 100337618 | cdh1.S | cadherin 1, type 1 S homeolog | Xenopus laevis (African clawed frog) | |
| 108709389 | ngf.S | nerve growth factor S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180351 | W01F3.2 | Uncharacterized protein | |
| 180628 | cht-1 | putative endochitinase | |
| 180780 | acn-1 | Inactive angiotensin-converting enzyme-related protein | |
| 180812 | scav-1 | SCAVenger receptor (CD36 family) related |
