osteoarthritis

Summary
Synonym
  • Osteoarthrosis and allied disorder
  • degenerative arthritis
  • degenerative joint disease
  • hypertrophic arthritis
  • osteoarthrosis
Definition
An arthritis that has_material_basis_in worn out cartilage located_in joint.
Super Class
arthritis
Disease Ontology
DOID:8398
UMLS
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 11 - 20 of 25 in total
Gene ID Gene Symbol Description Source
4314 MMP3 matrix metallopeptidase 3
4322 MMP13 matrix metallopeptidase 13
4921 DDR2 discoidin domain receptor tyrosine kinase 2
4982 TNFRSF11B TNF receptor superfamily member 11b
5443 POMC proopiomelanocortin
5743 PTGS2 prostaglandin-endoperoxide synthase 2
7123 CLEC3B C-type lectin domain family 3 member B
7917 BAG6 BAG cochaperone 6
8038 ADAM12 ADAM metallopeptidase domain 12
8200 GDF5 growth differentiation factor 5
Displaying all 10 entries
Gene ID Gene Symbol Description Source
11977 Atp7a ATPase, copper transporting, alpha polypeptide
12162 Bmp7 bone morphogenetic protein 7
12166 Bmpr1a bone morphogenetic protein receptor, type 1A
12814 Col11a1 collagen, type XI, alpha 1
14563 Gdf5 growth differentiation factor 5
17182 Matn3 matrilin 3
17897 Myl3 myosin, light polypeptide 3
18605 Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1
21812 Tgfbr1 transforming growth factor, beta receptor I
74155 Errfi1 ERBB receptor feedback inhibitor 1
Displaying all 3 entries
Gene ID Gene Symbol Description Source
25412 Col2a1 collagen type II alpha 1 chain
304135 Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
310738 Ngf nerve growth factor
Related Glycoprotein

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 8, 2025