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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
systemic lupus erythematosus
Summary
- Synonym
-
- Lupus Erythematosus, systemic
- SLE - Lupus Erythematosus, systemic
- disseminated lupus erythematosus
- Definition
- A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.
- Super Class
- connective tissue disease lupus erythematosus
External Links
- Disease Ontology
- DOID:9074
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- ORDO
- OMIM
- GARD
- MGI genotype (from TogoID)
-
- 4939884
- 5488500
- 5486338
- 5478500
- 5462253
- 5440213
- 5427085
- 4950056
- 4939894
- 5488510
- 4939883
- 4462257
- 4461031
- 4417904
- 4361591
- 3850627
- 3847256
- 3843174
- 6287976
- 7703667
- 7284986
- 7284974
- 7284944
- 6400352
- 6376530
- 6287981
- 6287978
- 3842290
- 6287975
- 6287973
- 5897270
- 5617219
- 5617218
- 5526095
- 5515634
- 5514345
- 3054644
- 3624973
- 3624942
- 3618363
- 3618357
- 3615496
- 3586344
- 3586342
- 3582186
- 3624974
- 3054643
- 2675118
- 2670276
- 2670272
- 2670271
- 2653187
- 2450135
- 2448998
- 3767995
- 3841485
- 3841484
- 3836922
- 3836921
- 3836920
- 3809239
- 3803013
- 3800222
- 2384126
- 3702859
- 3689926
- 3665495
- 3663104
- 3639668
- 3628445
- 3624982
- 3624975
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 6648 | SOD2 | superoxide dismutase 2 | |
| 6738 | RO60 | Ro60, Y RNA binding protein | |
| 6775 | STAT4 | signal transducer and activator of transcription 4 | |
| 6890 | TAP1 | transporter 1, ATP binding cassette subfamily B member | |
| 7035 | TFPI | tissue factor pathway inhibitor | |
| 7056 | THBD | thrombomodulin | |
| 7100 | TLR5 | toll like receptor 5 | |
| 7124 | TNF | tumor necrosis factor | |
| 7132 | TNFRSF1A | TNF receptor superfamily member 1A | |
| 7133 | TNFRSF1B | TNF receptor superfamily member 1B |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 23853 | Def6 | differentially expressed in FDCP 6 | |
| 27056 | Irf5 | interferon regulatory factor 5 | |
| 27221 | Chaf1a | chromatin assembly factor 1, subunit A | |
| 53791 | Tlr5 | toll-like receptor 5 | |
| 60504 | Il21r | interleukin 21 receptor | |
| 60505 | Il21 | interleukin 21 | |
| 66724 | Tab3 | TGF-beta activated kinase 1/MAP3K7 binding protein 3 | |
| 67332 | Snrpd3 | small nuclear ribonucleoprotein D3 | |
| 68652 | Tab2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | |
| 70839 | P2ry12 | purinergic receptor P2Y, G-protein coupled 12 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 116591 | Fcgr2a | Fc gamma receptor 2A | |
| 117029 | Ccr5 | C-C motif chemokine receptor 5 | |
| 156767 | Tnfrsf1b | TNF receptor superfamily member 1B | |
| 246097 | Fas | Fas cell surface death receptor | |
| 289211 | Fcgr2b | Fc gamma receptor 2B | |
| 298566 | C1qa | complement C1q A chain | |
| 300438 | Ldlr | low density lipoprotein receptor | |
| 304966 | Fcgr3a | Fc gamma receptor 3A | |
| 316519 | Slc11a1 | solute carrier family 11 member 1 | |
| 365769 | Il21 | interleukin 21 |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 373644 | ldlr.S | low density lipoprotein receptor S homeolog | Xenopus laevis (African clawed frog) | |
| 397757 | ldlr.L | low density lipoprotein receptor L homeolog | Xenopus laevis (African clawed frog) | |
| 734211 | epor.L | erythropoietin receptor L homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 174116 | gldi-2 | EGF-like domain-containing protein | |
| 177044 | smf-3 | NRAMP-like transporter smf-3 | |
| 178748 | zmp-3 | Matrix metalloproteinase-C | |
| 179105 | F09G2.8 | putative phospholipase D F09G2.8 | |
| 179632 | aman-2 | Alpha-mannosidase | |
| 180836 | W01C8.5 | DM13 domain-containing protein | |
| 180939 | smf-1 | NRAMP-like transporter smf-1 | |
| 191766 | smf-2 | NRAMP-like transporter smf-2 | |
| 3565419 | clr-1 | Receptor-type tyrosine-protein phosphatase;protein-tyrosine-phosphatase |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0002039 | Anorexia |
| HP:0001250 | Seizure |
| HP:0012378 | Fatigue |
| HP:0000716 | Depression |
| HP:0003493 | Antinuclear antibody positivity |
| HP:0001873 | Thrombocytopenia |
| HP:0000155 | Oral ulcer |
| HP:0001882 | Leukopenia |
| HP:0007417 | Discoid lupus rash |
| HP:0000822 | Hypertension |
