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Standards Ontologies Notations
type 2 diabetes mellitus

Summary
Synonym
  • NIDDM
  • insulin resistance
  • non-insulin-dependent diabetes mellitus
  • type 2 diabetes
  • type II diabetes mellitus
Definition
A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Super Class
diabetes mellitus
Disease Ontology
DOID:9352
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 325 in total
Gene ID Gene Symbol Description Source
19 ABCA1 ATP binding cassette subfamily A member 1
111 ADCY5 adenylate cyclase 5
133 ADM adrenomedullin
142 PARP1 poly(ADP-ribose) polymerase 1
150 ADRA2A adrenoceptor alpha 2A
154 ADRB2 adrenoceptor beta 2
155 ADRB3 adrenoceptor beta 3
177 AGER advanced glycosylation end-product specific receptor
183 AGT angiotensinogen
186 AGTR2 angiotensin II receptor type 2
Displaying entries 131 - 140 of 249 in total
Gene ID Gene Symbol Description Source
18605 Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1
18609 Pdx1 pancreatic and duodenal homeobox 1
18669 Abcb1b ATP-binding cassette, sub-family B member 1B
18671 Abcb1a ATP-binding cassette, sub-family B member 1A
18704 Pik3c2a phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
18708 Pik3r1 phosphoinositide-3-kinase regulatory subunit 1
18759 Prkci protein kinase C, iota
18762 Prkcz protein kinase C, zeta
18791 Plat plasminogen activator, tissue
18793 Plaur plasminogen activator, urokinase receptor
Displaying entries 1 - 10 of 166 in total
Gene ID Gene Symbol Description Source
24152 Asip agouti signaling protein
24179 Agt angiotensinogen
24182 Agtr2 angiotensin II receptor, type 2
24185 Akt1 AKT serine/threonine kinase 1
24192 Akr1b1 aldo-keto reductase family 1 member B1
24221 Avp arginine vasopressin
24225 Bdnf brain-derived neurotrophic factor
24241 Calca calcitonin-related polypeptide alpha
24296 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
24310 Ace angiotensin I converting enzyme
Displaying entries 61 - 70 of 80 in total
Gene ID Gene Symbol Description Source
44058 Ugt36A1 UDP-glycosyltransferase family 36 member A1
45815 Spn27A Serpin 27A
49804 Spn88Ea Serpin 88Ea
49808 Spn42Dd Serpin 42Dd
53501 Ugt304A1 UDP-glycosyltransferase family 304 member A1
53502 Ugt302K1 UDP-glycosyltransferase family 302 member K1
53503 Ugt303A1 UDP-glycosyltransferase family 303 member A1
53504 Ugt35E1 UDP-glycosyltransferase family 35 member E1
53506 Ugt35E2 UDP-glycosyltransferase family 35 member E2
53507 Ugt35C1 UDP-glycosyltransferase family 35 member C1
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
30173 nog3 noggin 3
30174 nog1 noggin 1
30262 ins preproinsulin
30667 mtnr1aa melatonin receptor 1A a
30668 mtnr1bb melatonin receptor 1Bb
30682 vegfaa vascular endothelial growth factor Aa
266751 adra2b adrenoceptor alpha 2B
321664 aldob aldolase b, fructose-bisphosphate
337685 ogt.1 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
393807 ppp1r3cb protein phosphatase 1, regulatory subunit 3Cb
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source Organism
373759 cnr1.S cannabinoid receptor 1 (brain) S homeolog Xenopus laevis (African clawed frog)
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
379783 akt2.L v-akt murine thymoma viral oncogene homolog 2 L homeolog Xenopus laevis (African clawed frog)
380341 pon2.L paraoxonase 2 L homeolog Xenopus laevis (African clawed frog)
394283 sdc2.S syndecan 2 S homeolog Xenopus laevis (African clawed frog)
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
398006 insr.L insulin receptor L homeolog Xenopus laevis (African clawed frog)
Displaying entries 61 - 69 of 69 in total
Gene ID Gene Symbol Description Source
181684 cpd-2 Peptidase M14 carboxypeptidase A domain-containing protein
181706 ace-1 Acetylcholinesterase 1
182513 gpx-3 Glutathione peroxidase 3
186632 ver-4 Tyrosine-protein kinase receptor ver-4
187297 poml-1 PON (paraoxonase) and MEC-6 Like
188252 lev-9 Protein lev-9
189173 W03G11.3 Putative alpha-L-fucosidase
191374 dhrr-1 G_PROTEIN_RECEP_F2_4 domain-containing protein
266823 parp-1 Poly [ADP-ribose] polymerase;Poly [ADP-ribose] polymerase 1
Displaying entries 1 - 10 of 32 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850369 ADP1 putative ATP-dependent permease ADP1
850391 NPP1 nucleotide diphosphatase/phosphodiesterase NPP1
850614 HXK1 hexokinase 1
850645 BPT1 ATP-binding cassette bilirubin transporter BPT1
850678 YBT1 bile acid-transporting ATPase YBT1
850886 ATG26 sterol 3-beta-glucosyltransferase
850979 PIG1 protein phosphatase regulator PIG1
851006 ECM38 gamma-glutamyltransferase
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
The Human Phenotype Ontology
Displaying all 4 entries
HPO ID HPO Term
HP:0000855 Insulin resistance
HP:0005978 Type II diabetes mellitus
HP:0000006 Autosomal dominant inheritance
HP:0003584 Late onset
Displaying all 6 entries
Gene ID Gene Symbol Description
2645 GCK glucokinase
2820 GPD2 glycerol-3-phosphate dehydrogenase 2
3990 LIPC lipase C, hepatic type
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
5506 PPP1R3A protein phosphatase 1 regulatory subunit 3A
6514 SLC2A2 solute carrier family 2 member 2
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024