heroin dependence

Summary
Definition
An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.
Super Class
opiate dependence
Disease Ontology
DOID:9976
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
Related Genes
Displaying entries 1 - 10 of 35 in total
Gene ID Gene Symbol Description Source
18 ABAT 4-aminobutyrate aminotransferase
43 ACHE acetylcholinesterase (Yt blood group)
148 ADRA1A adrenoceptor alpha 1A
217 ALDH2 aldehyde dehydrogenase 2 family member
355 FAS Fas cell surface death receptor
590 BCHE butyrylcholinesterase
627 BDNF brain derived neurotrophic factor
1129 CHRM2 cholinergic receptor muscarinic 2
1312 COMT catechol-O-methyltransferase
1385 CREB1 cAMP responsive element binding protein 1
Displaying entries 11 - 20 of 34 in total
Gene ID Gene Symbol Description Source
13490 Drd3 dopamine receptor D3
13491 Drd4 dopamine receptor D4
14102 Fas Fas cell surface death receptor
14402 Gabrb3 GABRB3, gamma-aminobutyric acid type A receptor subunit beta 3
14406 Gabrg2 gamma-aminobutyric acid type A receptor, subunit gamma 2
14415 Gad1 glutamate decarboxylase 1
14573 Gdnf glial cell line derived neurotrophic factor
14799 Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1)
14811 Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1)
15561 Htr3a 5-hydroxytryptamine (serotonin) receptor 3A
Displaying entries 1 - 10 of 25 in total
Gene ID Gene Symbol Description Source
24225 Bdnf brain-derived neurotrophic factor
24267 Comt catechol-O-methyltransferase
24318 Drd2 dopamine receptor D2
24409 Grin2a glutamate ionotropic receptor NMDA type subunit 2A
24415 Grm2 glutamate metabotropic receptor 2
24613 Oprd1 opioid receptor, delta 1
24898 Slc6a3 solute carrier family 6 member 3
24922 Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3
25085 Th tyrosine hydroxylase
25453 Gdnf glial cell derived neurotrophic factor
Displaying entries 1 - 10 of 11 in total
Gene ID Gene Symbol Description Source
32554 Lcch3 Ligand-gated chloride channel homolog 3
33007 Dop2R Dopamine 2-like receptor
36428 Mdr49 Multi drug resistance 49
36849 DAT Dopamine transporter
37892 mAChR-A muscarinic Acetylcholine Receptor, A-type
38726 Mdr65 Multi drug resistance 65
38742 GluRIA Glutamate receptor IA
41625 Ace Acetylcholine esterase
41726 Dop1R1 Dopamine 1-like receptor 1
43484 Dop1R2 Dopamine 1-like receptor 2
Displaying all 4 entries
Gene ID Gene Symbol Description Source
58133 ngfb nerve growth factor b (beta polypeptide)
114549 ache acetylcholinesterase (Yt blood group)
561372 comta catechol-O-methyltransferase a
565370 comtb catechol-O-methyltransferase b
Displaying all 4 entries
Gene ID Gene Symbol Description Source Organism
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
100127346 grin2a.L glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog Xenopus laevis (African clawed frog)
108709389 ngf.S nerve growth factor S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 16 in total
Gene ID Gene Symbol Description Source
171905 ace-2 Carboxylic ester hydrolase
175076 ace-3 Carboxylic ester hydrolase
175999 glr-2 Glutamate receptor 2
176204 glr-1 Glutamate receptor 1
176304 dat-1 Sodium-dependent dopamine transporter
176691 gab-1 Gamma-aminobutyric acid receptor subunit beta
178215 pgp-1 Multidrug resistance protein pgp-1
179347 dop-2 Dopamine receptor 2
179962 gar-3 Muscarinic acetylcholine receptor gar-3
180714 dop-1 Dopamine receptor 1
Displaying 1 entry
Gene ID Gene Symbol Description Source
853671 STE6 ATP-binding cassette a-factor transporter STE6

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