Homo sapiens (human)

Summary
Taxonomy ID
9606
PubChem Taxonomy
9606
Displaying entries 676 - 700 of 2090 in total
Pathway Name Protein Name ▼ UniProt ID Gene Symbol GlyTouCan ID
Displacement of DNA glycosylase by APEX1
  • AAG
  • ANPG
  • APE
  • APE1
  • APEX
  • APEX1
  • APX
  • HAP1
  • MBD4
  • MED1
  • MID1
  • MMH
  • MPG
  • MUTM
  • NTH1
  • NTHL1
  • OCTS3
  • OGG1
  • OGH1
  • REF1
  • SMUG1
  • TDG
Translesion synthesis by REV1
  • MAD2B
  • MAD2L2
  • PCNA
  • POLZ
  • REPA1
  • REPA2
  • REPA3
  • REV1
  • REV1L
  • REV3
  • REV3L
  • REV7
  • RFC1
  • RFC140
  • RFC2
  • RFC3
  • RFC4
  • RFC5
  • RPA1
  • RPA14
  • RPA2
  • RPA3
  • RPA32
  • RPA34
  • RPA70
  • RPS27A
  • UBA52
  • UBA80
  • UBB
  • UBC
  • UBCEP1
  • UBCEP2
Translesion synthesis by POLK
  • DINB1
  • MAD2B
  • MAD2L2
  • PCNA
  • POLK
  • POLZ
  • REPA1
  • REPA2
  • REPA3
  • REV1
  • REV1L
  • REV3
  • REV3L
  • REV7
  • RFC1
  • RFC140
  • RFC2
  • RFC3
  • RFC4
  • RFC5
  • RPA1
  • RPA14
  • RPA2
  • RPA3
  • RPA32
  • RPA34
  • RPA70
  • RPS27A
  • UBA52
  • UBA80
  • UBB
  • UBC
  • UBCEP1
  • UBCEP2
Translesion synthesis by POLI
  • MAD2B
  • MAD2L2
  • PCNA
  • POLI
  • POLZ
  • RAD30B
  • REPA1
  • REPA2
  • REPA3
  • REV1
  • REV1L
  • REV3
  • REV3L
  • REV7
  • RFC1
  • RFC140
  • RFC2
  • RFC3
  • RFC4
  • RFC5
  • RPA1
  • RPA14
  • RPA2
  • RPA3
  • RPA32
  • RPA34
  • RPA70
  • RPS27A
  • UBA52
  • UBA80
  • UBB
  • UBC
  • UBCEP1
  • UBCEP2
Translesion Synthesis by POLH
  • ARNIP
  • C1orf124
  • CHIMP
  • DVC1
  • HEL-220
  • HEL-S-70
  • KIAA1499
  • NPL4
  • NPLOC4
  • PCNA
  • PIRH2
  • POLH
  • RAD30
  • RAD30A
  • RCHY1
  • REPA1
  • REPA2
  • REPA3
  • RFC1
  • RFC140
  • RFC2
  • RFC3
  • RFC4
  • RFC5
  • RNF199
  • RPA1
  • RPA14
  • RPA2
  • RPA3
  • RPA32
  • RPA34
  • RPA70
  • RPS27A
  • SPRTN
  • UBA52
  • UBA80
  • UBB
  • UBC
  • UBCEP1
  • UBCEP2
  • UFD1
  • UFD1L
  • VCP
  • XPV
  • ZNF363
Termination of translesion DNA synthesis
  • CHRAC17
  • DINB1
  • DPE2
  • EFP
  • G1P2
  • ISG15
  • KIAA0039
  • KIAA0101
  • KIAA0190
  • NS5ATP9
  • PAF
  • PCLAF
  • PCNA
  • POLD
  • POLD1
  • POLD2
  • POLD3
  • POLD4
  • POLDS
  • POLE
  • POLE1
  • POLE2
  • POLE3
  • POLE4
  • POLH
  • POLI
  • POLK
  • RAD30
  • RAD30A
  • RAD30B
  • REPA1
  • REPA2
  • REPA3
  • REV1
  • REV1L
  • RFC1
  • RFC140
  • RFC2
  • RFC3
  • RFC4
  • RFC5
  • RNF147
  • RPA1
  • RPA14
  • RPA2
  • RPA3
  • RPA32
  • RPA34
  • RPA70
  • RPS27A
  • TRIM25
  • UBA52
  • UBA7
  • UBA80
  • UBB
  • UBC
  • UBCEP1
  • UBCEP2
  • UBCH8
  • UBE1L
  • UBE2
  • UBE2L6
  • UCRP
  • USP10
  • USP43
  • XPV
  • ZNF147
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway
  • APE
  • APE1
  • APEX
  • APEX1
  • APX
  • HAP1
  • POLB
  • REF1
Resolution of AP sites via the multiple-nucleotide patch replacement pathway
  • APE
  • APE1
  • APEX
  • APEX1
  • APX
  • HAP1
  • POLB
  • REF1
Inhibition of replication initiation of damaged DNA by RB1/E2F1
  • DP1
  • DP2
  • E2F1
  • POLA
  • POLA1
  • POLA2
  • PPP2CA
  • PPP2CB
  • PPP2R1A
  • PPP2R1B
  • PPP2R3B
  • PPP2R3L
  • PRIM1
  • PRIM2
  • PRIM2A
  • RB1
  • RBBP3
  • TFDP1
  • TFDP2
DNA replication initiation
  • CHRAC17
  • DPE2
  • POLA
  • POLA1
  • POLA2
  • POLE
  • POLE1
  • POLE2
  • POLE3
  • POLE4
  • PRIM1
  • PRIM2
  • PRIM2A
Polymerase switching
  • KIAA0039
  • PCNA
  • POLA
  • POLA1
  • POLA2
  • POLD
  • POLD1
  • POLD2
  • POLD3
  • POLD4
  • POLDS
  • PRIM1
  • PRIM2
  • PRIM2A
  • RFC1
  • RFC140
  • RFC2
  • RFC3
  • RFC4
  • RFC5
Removal of the Flap Intermediate
  • DNA2
  • DNA2L
  • FEN1
  • KIAA0039
  • KIAA0083
  • PCNA
  • POLA
  • POLA1
  • POLA2
  • POLD
  • POLD1
  • POLD2
  • POLD3
  • POLD4
  • POLDS
  • PRIM1
  • PRIM2
  • PRIM2A
  • RAD2
  • REPA1
  • REPA2
  • REPA3
  • RPA1
  • RPA14
  • RPA2
  • RPA3
  • RPA32
  • RPA34
  • RPA70
Defective Mismatch Repair Associated With MSH6
  • GTBP
  • MSH2
  • MSH6
Defective Mismatch Repair Associated With MSH3
  • DUC1
  • DUG
  • MSH2
  • MSH3
Defective Mismatch Repair Associated With MSH2
  • DUC1
  • DUG
  • GTBP
  • MSH2
  • MSH3
  • MSH6
Defective Mismatch Repair Associated With MLH1
  • COCA2
  • MLH1
  • PMS2
  • PMSL2
Defective Mismatch Repair Associated With PMS2
  • COCA2
  • MLH1
  • PMS2
  • PMSL2
Resolution of AP sites via the single-nucleotide replacement pathway
  • LIG3
  • POLB
  • XRCC1
Regulation of MITF-M-dependent genes involved in DNA damage repair and senescence
  • EST2
  • LIG1
  • TCS1
  • TERT
  • TRT
Early Phase of HIV Life Cycle
  • CYPA
  • FEN1
  • LIG1
  • PPIA
  • RAD2
  • gag
  • gag-pol
  • rev
  • vif
  • vpr
  • vpu
PCNA-Dependent Long Patch Base Excision Repair
  • APE
  • APE1
  • APEX
  • APEX1
  • APX
  • CHRAC17
  • DPE2
  • FEN1
  • HAP1
  • KIAA0039
  • LIG1
  • PCNA
  • POLB
  • POLD
  • POLD1
  • POLD2
  • POLD3
  • POLD4
  • POLDS
  • POLE
  • POLE1
  • POLE2
  • POLE3
  • POLE4
  • RAD2
  • REF1
  • REPA1
  • REPA2
  • REPA3
  • RFC1
  • RFC140
  • RFC2
  • RFC3
  • RFC4
  • RFC5
  • RPA1
  • RPA14
  • RPA2
  • RPA3
  • RPA32
  • RPA34
  • RPA70
Processive synthesis on the lagging strand
  • KIAA0039
  • LIG1
  • PCNA
  • POLA
  • POLA1
  • POLA2
  • POLD
  • POLD1
  • POLD2
  • POLD3
  • POLD4
  • POLDS
  • PRIM1
  • PRIM2
  • PRIM2A
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
  • COCA2
  • EXO1
  • EXOI
  • GTBP
  • HEX1
  • KIAA0039
  • LIG1
  • MLH1
  • MSH2
  • MSH6
  • PCNA
  • PMS2
  • PMSL2
  • POLD
  • POLD1
  • POLD2
  • POLD3
  • POLD4
  • POLDS
  • REPA1
  • REPA2
  • REPA3
  • RPA1
  • RPA14
  • RPA2
  • RPA3
  • RPA32
  • RPA34
  • RPA70
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
  • COCA2
  • DUC1
  • DUG
  • EXO1
  • EXOI
  • HEX1
  • KIAA0039
  • LIG1
  • MLH1
  • MSH2
  • MSH3
  • PCNA
  • PMS2
  • PMSL2
  • POLD
  • POLD1
  • POLD2
  • POLD3
  • POLD4
  • POLDS
  • REPA1
  • REPA2
  • REPA3
  • RPA1
  • RPA14
  • RPA2
  • RPA3
  • RPA32
  • RPA34
  • RPA70
Gap-filling DNA repair synthesis and ligation in GG-NER
  • CHRAC17
  • DINB1
  • DPE2
  • KIAA0039
  • LIG1
  • LIG3
  • PCNA
  • POLD
  • POLD1
  • POLD2
  • POLD3
  • POLD4
  • POLDS
  • POLE
  • POLE1
  • POLE2
  • POLE3
  • POLE4
  • POLK
  • REPA1
  • REPA2
  • REPA3
  • RFC1
  • RFC140
  • RFC2
  • RFC3
  • RFC4
  • RFC5
  • RPA1
  • RPA14
  • RPA2
  • RPA3
  • RPA32
  • RPA34
  • RPA70
  • RPS27A
  • UBA52
  • UBA80
  • UBB
  • UBC
  • UBCEP1
  • UBCEP2
  • XRCC1

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024