GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **701 - 725** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲
crizotinib-resistant ALK mutants	ALK tyrosine kinase receptor	Q9UM73	ALK
ASP-3026-resistant ALK mutants	ALK tyrosine kinase receptor	Q9UM73	ALK
ceritinib-resistant ALK mutants	ALK tyrosine kinase receptor	Q9UM73	ALK
brigatinib-resistant ALK mutants	ALK tyrosine kinase receptor	Q9UM73	ALK
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	Cingulin E3 ubiquitin-protein ligase SMURF1 Junctional adhesion molecule A Partitioning defective 3 homolog Partitioning defective 6 homolog alpha Peptidyl-prolyl cis-trans isomerase FKBP1A Polyubiquitin-B Polyubiquitin-C Protein kinase C zeta type Rho guanine nucleotide exchange factor 18 TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein Transforming protein RhoA Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P01137 P0CG47 P0CG48 P36897 P37173 P61586 P62942 P62979 P62987 Q05513 Q6ZSZ5 Q8TEW0 Q9HCE7 Q9NPB6 Q9P2M7 Q9Y624	ALK5 ARH12 ARHA ARHGEF18 CGN F11R FKBP1 FKBP12 FKBP1A JAM1 JCAM KIAA0521 KIAA1319 KIAA1625 PAR3 PAR3A PAR6A PARD3 PARD6A PKC2 PRKCZ RHO12 RHOA RPS27A SKR4 SMURF1 TGFB TGFB1 TGFBR1 TGFBR2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Downregulation of TGF-beta receptor signaling	BMP and activin membrane-bound inhibitor homolog E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase NEDD4-like E3 ubiquitin-protein ligase SMURF1 E3 ubiquitin-protein ligase SMURF2 Exportin-1 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 7 Myotubularin-related protein 4 Polyubiquitin-B Polyubiquitin-C Protein TMEPAI Protein phosphatase 1 regulatory subunit 15A Serine-threonine kinase receptor-associated protein Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Serine/threonine-protein phosphatase PP1-beta catalytic subunit Serine/threonine-protein phosphatase PP1-gamma catalytic subunit TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein Ubiquitin carboxyl-terminal hydrolase 15 Ubiquitin carboxyl-terminal hydrolase isozyme L5 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14980 O15105 O75807 P01137 P0CG47 P0CG48 P36873 P36897 P37173 P62136 P62140 P62979 P62987 P84022 Q13145 Q15796 Q969W9 Q96PU5 Q9HAU4 Q9HCE7 Q9NYA4 Q9UNE7 Q9Y3F4 Q9Y4E8 Q9Y5K5	ALK5 BAMBI CHIP CRM1 GADD34 KIAA0439 KIAA0529 KIAA0647 KIAA1625 MADH2 MADH3 MADH7 MADH8 MADR2 MAWD MTMR4 NEDD4L NEDL3 NMA PMEPA1 PPP1A PPP1CA PPP1CB PPP1CC PPP1R15A RPS27A SKR4 SMAD2 SMAD3 SMAD7 SMURF1 SMURF2 STAG1 STRAP STUB1 TGFB TGFB1 TGFBR1 TGFBR2 TMEPAI UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UCH37 UCHL5 UNRIP USP15 XPO1 ZFYVE11
TGF-beta receptor signaling activates SMADs	E3 ubiquitin-protein ligase CBL Furin Integrin alpha-8 Integrin alpha-V Integrin beta-1 Integrin beta-3 Integrin beta-5 Integrin beta-6 Integrin beta-8 Latent-transforming growth factor beta-binding protein 1 Latent-transforming growth factor beta-binding protein 2 Latent-transforming growth factor beta-binding protein 3 Latent-transforming growth factor beta-binding protein 4 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 NEDD8-conjugating enzyme Ubc12 NEDD8 Peptidyl-prolyl cis-trans isomerase FKBP1A TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta receptor type 3 Transforming growth factor beta-1 proprotein Transforming growth factor beta-2 proprotein Transforming growth factor beta-3 proprotein	P01137 P05106 P05556 P06756 P09958 P10600 P18084 P18564 P22681 P26012 P36897 P37173 P53708 P61081 P61812 P62942 P84022 Q03167 Q13485 Q14766 Q14767 Q15796 Q15843 Q8N2S1 Q9NS15	ALK5 C14orf141 CBL CBL2 DPC4 FKBP1 FKBP12 FKBP1A FNRB FUR FURIN GP3A ITGA8 ITGAV ITGB1 ITGB3 ITGB5 ITGB6 ITGB8 LTBP1 LTBP2 LTBP3 LTBP4 MADH2 MADH3 MADH4 MADR2 MDF2 MSK12 MSK8 NEDD8 PACE PCSK3 RNF55 SKR4 SMAD2 SMAD3 SMAD4 TGFB TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 TGFBR3 UBC12 UBE2M VNRA VTNR
TGFBR1 LBD Mutants in Cancer	Peptidyl-prolyl cis-trans isomerase FKBP1A TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein	P01137 P36897 P37173 P62942	ALK5 FKBP1 FKBP12 FKBP1A SKR4 TGFB TGFB1 TGFBR1 TGFBR2
SMAD2/3 Phosphorylation Motif Mutants in Cancer	Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein	P01137 P36897 P37173 P84022 Q15796	ALK5 MADH2 MADH3 MADR2 SKR4 SMAD2 SMAD3 TGFB TGFB1 TGFBR1 TGFBR2
TGFBR1 KD Mutants in Cancer	Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein	P01137 P36897 P37173 P84022 Q15796	ALK5 MADH2 MADH3 MADR2 SKR4 SMAD2 SMAD3 TGFB TGFB1 TGFBR1 TGFBR2
TGFBR2 Kinase Domain Mutants in Cancer	TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein	P01137 P36897 P37173	ALK5 SKR4 TGFB TGFB1 TGFBR1 TGFBR2
Transcriptional regulation of granulopoiesis	CCAAT/enhancer-binding protein alpha CCAAT/enhancer-binding protein beta CCAAT/enhancer-binding protein epsilon Core-binding factor subunit beta Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 1 Endothelial transcription factor GATA-2 Friend leukemia integration 1 transcription factor Granulocyte colony-stimulating factor receptor Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone acetyltransferase p300 Histone-lysine N-methyltransferase 2A Interleukin-6 receptor subunit alpha Krueppel-like factor 5 Lymphoid enhancer-binding factor 1 Myc proto-oncogene protein Protein DEK Retinoic acid receptor RXR-alpha Retinoic acid receptor alpha Runt-related transcription factor 1 Signal transducer and activator of transcription 3 T-cell acute lymphocytic leukemia protein 1 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor PU.1 Transcriptional activator Myb Zinc finger protein Gfi-1	O60814 P01106 P04908 P06899 P08887 P0C5Y9 P10242 P10276 P11802 P16104 P17542 P17676 P17947 P19793 P20671 P23527 P23769 P24941 P33778 P35659 P38936 P40763 P49715 P57053 P58876 P62805 P62807 P68431 P84243 Q01094 Q01196 Q01543 Q03164 Q09472 Q13887 Q13951 Q14186 Q14188 Q15744 Q16777 Q16778 Q6FI13 Q71DI3 Q71UI9 Q8N257 Q93077 Q93079 Q96A08 Q99062 Q99684 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9UJU2	ALL1 AML1 APRF BHLHA17 BHLHE39 BTEB2 CAP20 CBFA2 CBFB CDK2 CDK4 CDKN1 CDKN1A CDKN2 CEBP CEBPA CEBPB CEBPE CIP1 CKLF CSF3R CXXC7 DEK DP1 DP2 E2F1 EP300 FLI1 GATA2 GCSFR GFI1 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HRX HTRX IKLF IL6R KLF5 KMT2A LEF1 MDA6 MLL MLL1 MYB MYC NR1B1 NR2B1 P300 PIC1 RARA RBBP3 RUNX1 RXRA SCL SDI1 SPI1 STAT3 TAL1 TCF5 TCL5 TFDP1 TFDP2 TRX1 TSH2B WAF1 ZNF163
Suppression of apoptosis	Apoptosis inhibitor Rv3654c Apoptosis inhibitor Rv3655c Cathepsin G E3 ubiquitin-protein ligase RNF213 Glycogen synthase kinase-3 alpha Low molecular weight protein-tyrosine phosphatase A Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Possible Mce-family lipoprotein LprM (Mce-family lipoprotein Mce3E) Serine protease inhibitor Rv3364c Splicing factor, proline- and glutamine-rich Zinc finger protein RFP	O50393 O53971 O69622 O69623 P08311 P14373 P23246 P27361 P28482 P49840 P9WIA1 Q63HN8	ALO17 C17orf27 CTSG ERK1 ERK2 GSK3A KIAA1554 KIAA1618 MAPK1 MAPK3 MYSTR PRKM1 PRKM2 PRKM3 PSF RFP RNF213 RNF76 Rv3364c Rv3654c Rv3655c SFPQ TRIM27 lprM mce3E mptpA ptpA
Synthesis of 15-eicosatetraenoic acid derivatives	Glutathione peroxidase 1 Glutathione peroxidase 2 Phospholipid hydroperoxide glutathione peroxidase GPX4 Polyunsaturated fatty acid lipoxygenase ALOX15 Polyunsaturated fatty acid lipoxygenase ALOX15B Prostaglandin G/H synthase 2	O15296 P07203 P16050 P18283 P35354 P36969	ALOX15 ALOX15B COX2 GPX1 GPX2 GPX4 LOG15 PTGS2
Biosynthesis of E-series 18(S)-resolvins	15-hydroxyprostaglandin dehydrogenase [NAD(+)] Leukotriene A-4 hydrolase Polyunsaturated fatty acid 5-lipoxygenase Polyunsaturated fatty acid lipoxygenase ALOX15	P09917 P09960 P15428 P16050	ALOX15 ALOX5 HPGD LOG15 LOG5 LTA4 LTA4H PGDH1 SDR36C1
Biosynthesis of E-series 18(R)-resolvins	Leukotriene A-4 hydrolase Polyunsaturated fatty acid 5-lipoxygenase Polyunsaturated fatty acid lipoxygenase ALOX15	P09917 P09960 P16050	ALOX15 ALOX5 LOG15 LOG5 LTA4 LTA4H
Biosynthesis of protectins	Cytochrome P450 1A1 Cytochrome P450 1A2 Leukotriene A-4 hydrolase Polyunsaturated fatty acid lipoxygenase ALOX15	P04798 P05177 P09960 P16050	ALOX15 CYP1A1 CYP1A2 LOG15 LTA4 LTA4H
Synthesis of 5-eicosatetraenoic acids	Arachidonate 5-lipoxygenase-activating protein Glutathione peroxidase 1 Glutathione peroxidase 2 Leukotriene C4 synthase Phospholipid hydroperoxide glutathione peroxidase GPX4 Polyunsaturated fatty acid 5-lipoxygenase Serum paraoxonase/arylesterase 1 Serum paraoxonase/arylesterase 2 Serum paraoxonase/lactonase 3	P07203 P09917 P18283 P20292 P27169 P36969 Q15165 Q15166 Q16873	ALOX5 ALOX5AP FLAP GPX1 GPX2 GPX4 LOG5 LTC4S PON PON1 PON2 PON3
Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives	Polyunsaturated fatty acid 5-lipoxygenase Prostaglandin G/H synthase 2	P09917 P35354	ALOX5 COX2 LOG5 PTGS2
Biosynthesis of maresins	Bifunctional epoxide hydrolase 2 Polyunsaturated fatty acid 5-lipoxygenase	P09917 P34913	ALOX5 EPHX2 LOG5
Interleukin-18 signaling	Interleukin-13 Interleukin-18 receptor 1 Interleukin-18 receptor accessory protein Interleukin-18-binding protein Interleukin-18 Interleukin-37 Interleukin-4 Polyunsaturated fatty acid 5-lipoxygenase	O95256 O95998 P05112 P09917 P35225 Q13478 Q14116 Q9NZH6	ALOX5 FIL1Z IGIF IL13 IL18 IL18BP IL18R1 IL18RAP IL1F4 IL1F7 IL1H4 IL1R7 IL1RP1 IL1RRP IL37 IL4 LOG5 NC30
Biosynthesis of D-series resolvins	15-hydroxyprostaglandin dehydrogenase [NAD(+)] Leukotriene A-4 hydrolase Polyunsaturated fatty acid 5-lipoxygenase	P09917 P09960 P15428	ALOX5 HPGD LOG5 LTA4 LTA4H PGDH1 SDR36C1
Biosynthesis of aspirin-triggered D-series resolvins	Leukotriene A-4 hydrolase Polyunsaturated fatty acid 5-lipoxygenase	P09917 P09960	ALOX5 LOG5 LTA4 LTA4H
Phenylalanine metabolism	Dihydropteridine reductase Isoaspartyl peptidase/L-asparaginase Kynurenine--oxoglutarate transaminase 1 L-amino-acid oxidase Phenylalanine-4-hydroxylase Pterin-4-alpha-carbinolamine dehydratase	P00439 P09417 P61457 Q16773 Q7L266 Q96RQ9	ALP ASRGL1 CCBL1 CRASH DCOH DHPR FIG1 IL4I1 KYAT1 PAH PCBD PCBD1 QDPR SDR33C1
rRNA modification in the nucleus and cytosol	18S rRNA aminocarboxypropyltransferase DDB1- and CUL4-associated factor 13 H/ACA ribonucleoprotein complex subunit 1 H/ACA ribonucleoprotein complex subunit 2 H/ACA ribonucleoprotein complex subunit 3 H/ACA ribonucleoprotein complex subunit DKC1 HEAT repeat-containing protein 1 KRR1 small subunit processome component homolog Multifunctional methyltransferase subunit TRM112-like protein NHP2-like protein 1 Nucleolar complex protein 4 homolog Nucleolar protein 11 Nucleolar protein 14 Nucleolar protein 56 Nucleolar protein 58 Nucleolar protein 6 Periodic tryptophan protein 2 homolog Probable 18S rRNA (guanine-N(7))-methyltransferase Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase Probable ATP-dependent RNA helicase DDX47 Probable ATP-dependent RNA helicase DDX49 Probable ATP-dependent RNA helicase DDX52 Probable ATP-dependent RNA helicase DHX37 Probable U3 small nucleolar RNA-associated protein 11 Probable dimethyladenosine transferase Protein RRP5 homolog RNA 3'-terminal phosphate cyclase-like protein RNA cytidine acetyltransferase RNA-binding protein PNO1 Ribosomal RNA processing protein 36 homolog Ribosomal RNA small subunit methyltransferase NEP1 Ribosomal RNA-processing protein 7 homolog A Ribosome biogenesis protein BMS1 homolog Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small subunit processome component 20 homolog Something about silencing protein 10 THUMP domain-containing protein 1 Transducin beta-like protein 3 U3 small nucleolar RNA-associated protein 14 homolog A U3 small nucleolar RNA-associated protein 14 homolog C U3 small nucleolar RNA-associated protein 15 homolog U3 small nucleolar RNA-associated protein 18 homolog U3 small nucleolar RNA-associated protein 25 homolog U3 small nucleolar RNA-associated protein 4 homolog U3 small nucleolar RNA-associated protein 6 homolog U3 small nucleolar RNA-interacting protein 2 U3 small nucleolar ribonucleoprotein protein IMP3 U3 small nucleolar ribonucleoprotein protein IMP4 U3 small nucleolar ribonucleoprotein protein MPP10 WD repeat-containing protein 36 WD repeat-containing protein 3 WD repeat-containing protein 43 WD repeat-containing protein 46 WD repeat-containing protein 75 rRNA 2'-O-methyltransferase fibrillarin rRNA-processing protein FCF1 homolog	O00566 O00567 O15213 O43709 O43818 O60832 O75691 P15880 P22087 P46087 P46781 P55769 P62081 P62263 P62753 P78316 Q12788 Q13601 Q14690 Q14692 Q15061 Q15269 Q5TAP6 Q68CQ4 Q8IWA0 Q8IY37 Q8NI36 Q8TED0 Q92979 Q969X6 Q96EU6 Q96G21 Q9BVI4 Q9BVJ6 Q9H0A0 Q9H0S4 Q9H583 Q9H6R4 Q9H8H0 Q9NPE3 Q9NQZ2 Q9NRX1 Q9NV06 Q9NV31 Q9NX24 Q9NXG2 Q9NY12 Q9NYH9 Q9UI30 Q9UJK0 Q9UNQ2 Q9UNX4 Q9Y2P8 Q9Y2R4 Q9Y2X3 Q9Y324 Q9Y3A2 Q9Y3A4 Q9Y5J1 Q9Y6V7	ALP BAP28 BING4 BMS1 BMS1L BUD23 BXDC4 C14orf111 C15orf12 C16orf42 C17orf40 C1orf107 C2F C4orf9 C6orf11 C6orf153 CIRH1A CRLZ1 DCAF13 DDX37 DDX47 DDX49 DDX52 DEF DHX37 DIEXF DIMT1 DIMT1L DKC1 DRIM EMG1 FBL FCF1 FIB1 FLRN GAR1 HCA66 HEATR1 HRB2 IMP3 IMP4 KIAA0007 KIAA0185 KIAA0187 KIAA0266 KIAA1517 KIAA1709 KIAA1988 KRR1 MERM1 MHAT MPHOSPH10 MPP10 MRPS4 NAT10 NHP2 NHP2L1 NOC4L NOL1 NOL11 NOL14 NOL5 NOL5A NOL6 NOLA1 NOLA2 NOLA3 NOLA4 NOP10 NOP14 NOP2 NOP5 NOP56 NOP58 NSUN1 PDCD11 PNO1 PWP2 PWP2H RCL1 RNAC RNU3IP2 ROK1 RPC2 RPCL1 RPS14 RPS2 RPS4 RPS6 RPS7 RPS9 RRP36 RRP7A RRP9 RTC2 SAS10 SAZD SDCCAG16 SNU13 TBL3 THUMPD1 TRMT112 TSR3 U355K UND313L UTP10 UTP11 UTP11L UTP14A UTP14C UTP15 UTP17 UTP18 UTP20 UTP25 UTP3 UTP4 UTP5 UTP6 WBSCR22 WDR3 WDR36 WDR43 WDR46 WDR50 WDR75 WDSOF1 cPERP-E

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