GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **901 - 925** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol
Keratan sulfate biosynthesis	Aggrecan core protein Beta-1,4-galactosyltransferase 1 Beta-1,4-galactosyltransferase 2 Beta-1,4-galactosyltransferase 3 Beta-1,4-galactosyltransferase 4 Beta-1,4-galactosyltransferase 5 Beta-1,4-galactosyltransferase 6 Beta-1,4-glucuronyltransferase 1 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 Carbohydrate sulfotransferase 1 Carbohydrate sulfotransferase 2 Carbohydrate sulfotransferase 5 Carbohydrate sulfotransferase 6 Fibromodulin Keratocan Lumican Mimecan N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 Nucleotide sugar transporter SLC35D2 Osteomodulin Prolargin Type 2 lactosamine alpha-2,3-sialyltransferase UDP-GlcNAc	O43286 O43505 O43916 O60512 O60513 O60909 O60938 P15291 P16112 P20774 P51884 P51888 Q06828 Q11201 Q11203 Q11206 Q16842 Q76EJ3 Q8NFL0 Q99983 Q9C0J1 Q9GZS9 Q9GZX3 Q9NY97 Q9UBX8 Q9Y274 Q9Y2A9 Q9Y4C5	ACAN AGC1 B3GALT7 B3GALT8 B3GNT1 B3GNT2 B3GNT3 B3GNT4 B3GNT6 B3GNT7 B4GALT1 B4GALT2 B4GALT3 B4GALT4 B4GALT5 B4GALT6 B4GAT1 CGS23 CHST1 CHST2 CHST5 CHST6 CSPG1 FM FMOD GGTB2 GN6ST HFRC KERA LDC LUM MSK16 NANTA3 OGN OIF OMD PRELP SIAT10 SIAT4 SIAT4A SIAT4B SIAT4C SIAT6 SLC35D2 SLRR2A SLRR2B SLRR2C SLRR2D SLRR2E SLRR3A ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST3GAL6 STZ TMEM3 UGTREL8
O-linked glycosylation of mucins	Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase Alpha-1,4-N-acetylglucosaminyltransferase Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase Beta-1,4-galactosyltransferase 5 Beta-1,4-galactosyltransferase 6 C1GALT1-specific chaperone 1 Carbohydrate sulfotransferase 4 Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 Inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5 Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase Mucin-12 Mucin-13 Mucin-15 Mucin-16 Mucin-17 Mucin-19 Mucin-1 Mucin-20 Mucin-21 Mucin-2 Mucin-3A Mucin-3B Mucin-4 Mucin-5AC Mucin-5B Mucin-6 Mucin-7 Mucin-like protein 1 N-acetylgalactosaminyltransferase 7 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 Polypeptide N-acetylgalactosaminyltransferase 10 Polypeptide N-acetylgalactosaminyltransferase 11 Polypeptide N-acetylgalactosaminyltransferase 12 Polypeptide N-acetylgalactosaminyltransferase 13 Polypeptide N-acetylgalactosaminyltransferase 14 Polypeptide N-acetylgalactosaminyltransferase 15 Polypeptide N-acetylgalactosaminyltransferase 16 Polypeptide N-acetylgalactosaminyltransferase 17 Polypeptide N-acetylgalactosaminyltransferase 18 Polypeptide N-acetylgalactosaminyltransferase 1 Polypeptide N-acetylgalactosaminyltransferase 2 Polypeptide N-acetylgalactosaminyltransferase 3 Polypeptide N-acetylgalactosaminyltransferase 4 Polypeptide N-acetylgalactosaminyltransferase 5 Polypeptide N-acetylgalactosaminyltransferase 6 Polypeptide N-acetylgalactosaminyltransferase 9 Polypeptide N-acetylgalactosaminyltransferase-like 6 Probable polypeptide N-acetylgalactosaminyltransferase 8 Queuosine-tRNA galactosyltransferase UDP-GlcNAc UDP-GlcNAc UDP-GlcNAc	O43286 O95395 P15941 P98088 Q02505 Q02742 Q02817 Q10471 Q10472 Q14435 Q49A17 Q5SSG8 Q67FW5 Q685J3 Q6IS24 Q6P9A2 Q6UX72 Q6W4X9 Q6ZMB0 Q6ZNI0 Q7Z4T8 Q7Z5P9 Q7Z7M8 Q7Z7M9 Q86SF2 Q86SR1 Q8IUC8 Q8IXK2 Q8N307 Q8N387 Q8N3T1 Q8N428 Q8N4A0 Q8NCG5 Q8NCL4 Q8NCW6 Q8NFL0 Q8TAX7 Q8WXI7 Q96DR8 Q96EU7 Q96FL9 Q99102 Q9BYG0 Q9C0J1 Q9H195 Q9H3R2 Q9HC84 Q9HCQ5 Q9NS00 Q9NY28 Q9NY97 Q9P109 Q9UBX8 Q9UKN1 Q9UNA3 Q9Y2A9	A4GNT B3GALT7 B3GALT8 B3GNT1 B3GNT2 B3GNT3 B3GNT4 B3GNT5 B3GNT6 B3GNT7 B3GNT8 B3GNT9 B3GNTL1 B4GALT5 B4GALT6 BGALT15 C1GALT1 C1GALT1C1 C20orf105 C6orf205 CA125 CHST4 COSMC DRCC1 GALNT1 GALNT10 GALNT11 GALNT12 GALNT13 GALNT14 GALNT15 GALNT16 GALNT17 GALNT18 GALNT2 GALNT3 GALNT4 GALNT5 GALNT6 GALNT7 GALNT8 GALNT9 GALNTL1 GALNTL2 GALNTL4 GALNTL5 GALNTL6 GCNT1 GCNT3 GCNT4 GCNT7 KIAA1130 KIAA1359 KIAA1918 MG2 MUC1 MUC11 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC2 MUC20 MUC21 MUC3 MUC3A MUC3B MUC4 MUC5 MUC5AC MUC5B MUC6 MUC7 MUCL1 NACGT2 PUM QTGAL RECC SBEM SMUC TMEM3 WBSCR17
Attachment of GPI anchor to uPAR	GPI inositol-deacylase GPI transamidase component PIG-S GPI transamidase component PIG-T GPI-anchor transamidase Glycosylphosphatidylinositol anchor attachment 1 protein Phosphatidylinositol glycan anchor biosynthesis class U protein Urokinase plasminogen activator surface receptor	O43292 Q03405 Q75T13 Q92643 Q969N2 Q96S52 Q9H490	CDC91L1 GAA1 GPAA1 GPI8 MO3 PGAP1 PIGK PIGS PIGT PIGU PLAUR UPAR
Ligand-independent caspase activation via DCC	Caspase-3 Caspase-9 DCC-interacting protein 13-alpha Death-associated protein kinase 1 Death-associated protein kinase 2 Death-associated protein kinase 3 Melanoma-associated antigen D1 Netrin receptor DCC Netrin receptor UNC5A Netrin receptor UNC5B	O43293 P42574 P43146 P53355 P55211 Q6ZN44 Q8IZJ1 Q9UIK4 Q9UKG1 Q9Y5V3	APPL APPL1 CASP3 CASP9 CPP32 DAPK DAPK1 DAPK2 DAPK3 DCC DIP13A IGDCC1 KIAA1428 KIAA1976 MAGED1 MCH6 NRAGE P53RDL1 UNC5A UNC5B UNC5H1 UNC5H2 ZIPK
Inactivation of CDC42 and RAC1	Cell division control protein 42 homolog Ras-related C3 botulinum toxin substrate 1 Rho GTPase-activating protein 39 Roundabout homolog 1 SLIT-ROBO Rho GTPase-activating protein 1 SLIT-ROBO Rho GTPase-activating protein 2 SLIT-ROBO Rho GTPase-activating protein 3 Slit homolog 2 protein	O43295 O75044 O94813 P60953 P63000 Q7Z6B7 Q9C0H5 Q9Y6N7	ARHGAP13 ARHGAP14 ARHGAP34 ARHGAP39 CDC42 DUTT1 FNBP2 KIAA0411 KIAA0456 KIAA1156 KIAA1304 KIAA1688 MEGAP RAC1 ROBO1 SLIL3 SLIT2 SRGAP1 SRGAP2 SRGAP2A SRGAP3 TC25
Glucagon signaling in metabolic regulation	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Glucagon receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein subunit beta-4 Pro-glucagon	O43306 O60262 O60266 O60503 O95622 P01275 P16520 P40145 P47871 P50150 P50151 P51828 P59768 P61952 P62873 P62879 P63092 P63215 P63218 Q08462 Q08828 Q5JWF2 Q8NFM4 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GCG GCGR GNAS GNAS1 GNB1 GNB2 GNB3 GNB4 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT10 GNGT11 GNGT3 GNGT4 GNGT5 GNGT7 GNGT9 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060
Hedgehog 'off' state	Adenylate cyclase type 10 Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Centriole and centriolar satellite protein OFD1 Cytoplasmic dynein 2 heavy chain 1 G-protein coupled receptor 161 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Intraflagellar transport protein 122 homolog Intraflagellar transport protein 140 homolog Intraflagellar transport protein 172 homolog Intraflagellar transport protein 52 homolog Intraflagellar transport protein 57 homolog Intraflagellar transport protein 88 homolog Kinesin-like protein KIF3A Kinesin-like protein KIF7 Protein fantom Protein fuzzy homolog Protein inturned Protein patched homolog 1 Protein smoothened Suppressor of fused homolog Tectonic-like complex member MKS1 Tetratricopeptide repeat protein 21B Transcriptional activator GLI3 Tubby-related protein 3 WD repeat-containing protein 19 WD repeat-containing protein 35 Zinc finger protein GLI1 Zinc finger protein GLI2 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O43306 O60266 O60503 O75386 O75665 O95622 P08151 P10070 P10071 P10644 P13861 P17612 P22612 P22694 P31321 P31323 P40145 P51828 P63092 Q08462 Q08828 Q13099 Q13635 Q2M1P5 Q5JWF2 Q68CZ1 Q7Z4L5 Q8N6U8 Q8NCM8 Q8NEZ3 Q8NFM4 Q96PN6 Q96RY7 Q99835 Q9BT04 Q9HBG6 Q9NWB7 Q9NXB0 Q9P2L0 Q9UG01 Q9ULD6 Q9UMX1 Q9Y366 Q9Y496	ADCY1 ADCY10 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 C20orf9 CXorf5 DERP8 DHC1B DHC2 DNCH2 DYH1B DYNC2H1 ESRRBL1 FTM FUZ FY GLI GLI1 GLI2 GLI3 GNAS GNAS1 GPR161 GSP HIPPI IFT121 IFT122 IFT139 IFT140 IFT144 IFT172 IFT52 IFT57 IFT88 INTU KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA0590 KIAA1005 KIAA1060 KIAA1179 KIAA1284 KIAA1336 KIAA1638 KIAA1992 KIAA1997 KIF3 KIF3A KIF7 MKS1 NGD5 NPHP8 OFD1 PDZD6 PDZK6 PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B PTCH PTCH1 RPGRIP1L SAC SMO SMOH SPG SUFU TG737 THP TSE1 TTC10 TTC21B TUBL3 TULP3 WDR10 WDR140 WDR19 WDR35 WDTC2
PKA activation	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Calmodulin-1 Neurobeachin cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O43306 O60266 O60503 O95622 P0DP23 P10644 P13861 P17612 P22612 P22694 P31321 P31323 P40145 P51828 Q08462 Q08828 Q8NFM4 Q8NFP9	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 BCL8B CALM CALM1 CAM CAM1 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 KIAA1544 LYST2 NBEA PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B TSE1
PKA activation in glucagon signalling	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O43306 O60266 O60503 O95622 P10644 P13861 P17612 P22612 P22694 P31321 P31323 P40145 P51828 P63092 Q08462 Q08828 Q5JWF2 Q8NFM4	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GNAS GNAS1 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B TSE1
Adenylate cyclase activating pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(olf) subunit alpha	O43306 O60266 O60503 O95622 P38405 P40145 P51828 Q08462 Q08828 Q8NFM4	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GNAL KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060
Synthesis of pyrophosphates in the cytosol	Diphosphoinositol polyphosphate phosphohydrolase 1 Diphosphoinositol polyphosphate phosphohydrolase 2 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha Diphosphoinositol polyphosphate phosphohydrolase 3-beta Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 Inositol hexakisphosphate kinase 1 Inositol hexakisphosphate kinase 3 Inositol-pentakisphosphate 2-kinase Inositol-tetrakisphosphate 1-kinase	O43314 O95989 Q13572 Q6PFW1 Q8NFP7 Q92551 Q96G61 Q96PC2 Q9H8X2 Q9NZJ9	APS1 APS2 C9orf12 DIPP DIPP1 DIPP2 DIPP3A DIPP3B HISPPD1 HISPPD2A IHPK1 IHPK3 IP6K IP6K1 IP6K3 IPPK IPS1 ITPK1 KIAA0263 KIAA0377 KIAA0433 KIAA0487 NUDT10 NUDT11 NUDT3 NUDT4 PPIP5K1 PPIP5K2 VIP1 VIP2
Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells	Homeobox protein Nkx-2.2 Insulinoma-associated protein 1 Neurogenic differentiation factor 1 Neurogenin-3 Paired box protein Pax-4	O43316 O95096 Q01101 Q13562 Q9Y4Z2	ATOH5 BHLHA3 BHLHA7 IA1 INSM1 NEUROD NEUROD1 NEUROG3 NGN3 NKX2-2 NKX2.2 NKX2B PAX4
ALPK1 signaling pathway	Alpha-protein kinase 1 Mitogen-activated protein kinase kinase kinase 7 Polyubiquitin-B Polyubiquitin-C TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 TRAF-interacting protein with FHA domain-containing protein A Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O43318 P0CG47 P0CG48 P62979 P62987 Q15750 Q8N5C8 Q96CG3 Q96QP1 Q9NYJ8 Q9Y4K3	ALPK1 KIAA0733 KIAA1527 LAK MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 RNF85 RPS27A T2BP TAB1 TAB2 TAB3 TAK1 TIFA TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
FRS-mediated FGFR4 signaling	Beta-klotho Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O43320 O43559 O76093 O95750 P01111 P01112 P05230 P08620 P09038 P10767 P22455 P31371 Q06124 Q07889 Q86Z14 Q8WU20 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB FGFR4 FRS2 FRS3 HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF JTK2 KLB KS3 NRAS PTP2C PTPN11 SHPTP2 SOS1 TKF
FRS-mediated FGFR3 signaling	Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O43320 O43559 O76093 P01111 P01112 P05230 P08620 P09038 P31371 Q06124 Q07889 Q8WU20 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB FRS2 FRS3 HRAS HRAS1 HST HSTF1 HYPF KS3 NRAS PTP2C PTPN11 SHPTP2 SOS1
SHC-mediated cascade:FGFR4	Beta-klotho Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 GTPase HRas GTPase NRas Son of sevenless homolog 1	O43320 O76093 O95750 P01111 P01112 P05230 P08620 P09038 P10767 P22455 P31371 Q07889 Q86Z14 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB FGFR4 HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF JTK2 KLB KS3 NRAS SOS1 TKF
Negative regulation of FGFR4 signaling	Beta-klotho E3 ubiquitin-protein ligase CBL Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O43320 O76093 O95750 P05230 P08620 P09038 P0CG47 P0CG48 P10767 P22455 P22681 P27361 P28482 P31371 P62979 P62987 Q06124 Q86Z14 Q8WU20 Q9GZV9 Q9NP95	CBL CBL2 ERK1 ERK2 FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB FGFR4 FRS2 HST HST2 HSTF1 HSTF2 HYPF JTK2 KLB KS3 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 PTP2C PTPN11 RNF55 RPS27A SHPTP2 TKF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Phospholipase C-mediated cascade; FGFR4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Beta-klotho Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor 4	O43320 O76093 O95750 P05230 P08620 P09038 P10767 P19174 P22455 P31371 Q86Z14 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB FGFR4 HST HST2 HSTF1 HSTF2 HYPF JTK2 KLB KS3 PLC1 PLCG1 TKF
PI-3K cascade:FGFR4	Beta-klotho Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 GRB2-associated-binding protein 1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Tyrosine-protein phosphatase non-receptor type 11	O43320 O76093 O95750 P05230 P08620 P09038 P10767 P22455 P27986 P31371 P42336 Q06124 Q13480 Q86Z14 Q8WU20 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB FGFR4 FRS2 GAB1 GRB1 HST HST2 HSTF1 HSTF2 HYPF JTK2 KLB KS3 PIK3CA PIK3R1 PTP2C PTPN11 SHPTP2 TKF
FGFR4 ligand binding and activation	Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor 4	O43320 O76093 O95750 P05230 P08620 P09038 P10767 P22455 P31371 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB FGFR4 HST HST2 HSTF1 HSTF2 HYPF JTK2 KS3 TKF
Signaling by FGFR3 in disease	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Son of sevenless homolog 1	O43320 O76093 P01111 P01112 P05230 P08620 P09038 P19174 P22607 P27986 P31371 P42336 Q07889 Q13480 Q8WU20 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB FGFR3 FRS2 GAB1 GRB1 HRAS HRAS1 HST HSTF1 HYPF JTK4 KS3 NRAS PIK3CA PIK3R1 PLC1 PLCG1 SOS1
SHC-mediated cascade:FGFR3	Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9 GTPase HRas GTPase NRas Son of sevenless homolog 1	O43320 O76093 P01111 P01112 P05230 P08620 P09038 P31371 Q07889 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB HRAS HRAS1 HST HSTF1 HYPF KS3 NRAS SOS1
Negative regulation of FGFR3 signaling	E3 ubiquitin-protein ligase CBL Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O43320 O76093 P05230 P08620 P09038 P0CG47 P0CG48 P22681 P27361 P28482 P31371 P62979 P62987 Q06124 Q8WU20 Q9GZV9 Q9NP95	CBL CBL2 ERK1 ERK2 FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB FRS2 HST HSTF1 HYPF KS3 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 PTP2C PTPN11 RNF55 RPS27A SHPTP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
FGFR2c ligand binding and activation	Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9	O43320 O76093 P05230 P08620 P09038 P10767 P31371 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB HST HST2 HSTF1 HSTF2 HYPF KS3
Phospholipase C-mediated cascade; FGFR3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9	O43320 O76093 P05230 P08620 P09038 P19174 P31371 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB HST HSTF1 HYPF KS3 PLC1 PLCG1

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