GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1626 - 1650** of **2090** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism
SMAC (DIABLO) binds to IAPs	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999 Q9NR28	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS DIABLO IAP3 KIAA0413 MCH3 MCH6 SMAC XIAP	Homo sapiens (human)
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999 Q9NR28	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS DIABLO IAP3 KIAA0413 MCH3 MCH6 SMAC XIAP	Homo sapiens (human)
SMAC, XIAP-regulated apoptotic response	Caspase-3 Caspase-7 Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP	P42574 P55210 P98170 Q9NR28	API3 BIRC4 CASP3 CASP7 CPP32 DIABLO IAP3 MCH3 SMAC XIAP	Homo sapiens (human)
SMAD2/3 MH2 Domain Mutants in Cancer	Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4	P84022 Q13485 Q15796	DPC4 MADH2 MADH3 MADH4 MADR2 SMAD2 SMAD3 SMAD4	Homo sapiens (human)
SMAD2/3 Phosphorylation Motif Mutants in Cancer	Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein	P01137 P36897 P37173 P84022 Q15796	ALK5 MADH2 MADH3 MADR2 SKR4 SMAD2 SMAD3 TGFB TGFB1 TGFBR1 TGFBR2	Homo sapiens (human)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	Collagen alpha-2(I) chain Cyclin-C Cyclin-K Cyclin-T1 Cyclin-T2 Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 8 Cyclin-dependent kinase 9 E3 ubiquitin-protein ligase Arkadia Furin Histone acetyltransferase p300 Histone deacetylase 1 Homeobox protein TGIF1 Homeobox protein TGIF2 Menin Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog 7 Myc proto-oncogene protein Plasminogen activator inhibitor 1 Polyubiquitin-B Polyubiquitin-C Retinoblastoma-like protein 1 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F4 Transcription factor E2F5 Transcription factor JunB Transcription factor Sp1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WW domain-containing transcription regulator protein 1 Y-box-binding protein 1	O00255 O15105 O60563 O60583 O75909 P01106 P05121 P08047 P08123 P09958 P0CG47 P0CG48 P17275 P24863 P27361 P28482 P28749 P42772 P49336 P50750 P62979 P62987 P67809 P84022 Q09472 Q13485 Q13547 Q14186 Q14188 Q15329 Q15583 Q15796 Q16254 Q6ZNA4 Q9GZN2 Q9GZV5	BHLHE39 CCNC CCNK CCNT1 CCNT2 CDC2L4 CDK8 CDK9 CDKN2B COL1A2 CPR4 DP1 DP2 DPC4 E2F4 E2F5 EP300 ERK1 ERK2 FUR FURIN HDAC1 JUNB MADH2 MADH3 MADH4 MADH7 MADH8 MADR2 MAPK1 MAPK3 MEN1 MTS2 MYC NSEP1 P300 PACE PAI1 PCSK3 PLANH1 PRKM1 PRKM2 PRKM3 RBL1 RNF111 RPD3L1 RPS27A SCG2 SERPINE1 SMAD2 SMAD3 SMAD4 SMAD7 SP1 TAK TAZ TFDP1 TFDP2 TGIF TGIF1 TGIF2 TSFP1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WWTR1 YB1 YBX1	Homo sapiens (human)
SMAD4 MH2 Domain Mutants in Cancer	Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4	P84022 Q13485 Q15796	DPC4 MADH2 MADH3 MADH4 MADR2 SMAD2 SMAD3 SMAD4	Homo sapiens (human)
SOS-mediated signalling	GTPase HRas GTPase NRas Insulin receptor substrate 1 Insulin receptor substrate 2 Son of sevenless homolog 1	P01111 P01112 P35568 Q07889 Q9Y4H2	HRAS HRAS1 IRS1 IRS2 NRAS SOS1	Homo sapiens (human)
SRP-dependent cotranslational protein targeting to membrane	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 Large ribosomal subunit protein P1 Large ribosomal subunit protein P2 Large ribosomal subunit protein eL13 Large ribosomal subunit protein eL14 Large ribosomal subunit protein eL15 Large ribosomal subunit protein eL18 Large ribosomal subunit protein eL19 Large ribosomal subunit protein eL20 Large ribosomal subunit protein eL21 Large ribosomal subunit protein eL22 Large ribosomal subunit protein eL24 Large ribosomal subunit protein eL27 Large ribosomal subunit protein eL28 Large ribosomal subunit protein eL29 Large ribosomal subunit protein eL30 Large ribosomal subunit protein eL31 Large ribosomal subunit protein eL32 Large ribosomal subunit protein eL33 Large ribosomal subunit protein eL34 Large ribosomal subunit protein eL36 Large ribosomal subunit protein eL37 Large ribosomal subunit protein eL38 Large ribosomal subunit protein eL39 Large ribosomal subunit protein eL42 Large ribosomal subunit protein eL43 Large ribosomal subunit protein eL6 Large ribosomal subunit protein eL8 Large ribosomal subunit protein uL10 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL13 Large ribosomal subunit protein uL14 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL16 Large ribosomal subunit protein uL18 Large ribosomal subunit protein uL1 Large ribosomal subunit protein uL22 Large ribosomal subunit protein uL23 Large ribosomal subunit protein uL24 Large ribosomal subunit protein uL29 Large ribosomal subunit protein uL2 Large ribosomal subunit protein uL30 Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL4 Large ribosomal subunit protein uL5 Large ribosomal subunit protein uL6 Protein transport protein Sec61 subunit alpha isoform 1 Protein transport protein Sec61 subunit alpha isoform 2 Protein transport protein Sec61 subunit beta Protein transport protein Sec61 subunit gamma Ribosomal protein eL22-like Ribosomal protein eL39-like 2 Ribosomal protein eL42-like Ribosomal protein eS27-like Ribosomal protein uL16-like Ribosomal protein uL24-like Ribosomal protein uL3-like Signal peptidase complex catalytic subunit SEC11A Signal peptidase complex catalytic subunit SEC11C Signal peptidase complex subunit 1 Signal peptidase complex subunit 2 Signal peptidase complex subunit 3 Signal recognition particle 14 kDa protein Signal recognition particle 19 kDa protein Signal recognition particle 9 kDa protein Signal recognition particle receptor subunit alpha Signal recognition particle receptor subunit beta Signal recognition particle subunit SRP54 Signal recognition particle subunit SRP68 Signal recognition particle subunit SRP72 Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS32 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Translocating chain-associated membrane protein 1 Translocon-associated protein subunit alpha Translocon-associated protein subunit beta Translocon-associated protein subunit delta Translocon-associated protein subunit gamma Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O76094 P04843 P04844 P05386 P05387 P05388 P08240 P08708 P08865 P09132 P15880 P18077 P18124 P18621 P22090 P23396 P25398 P26373 P27635 P30050 P32969 P35268 P36578 P37108 P39019 P39023 P39656 P40429 P42677 P42766 P43307 P43308 P46776 P46777 P46778 P46779 P46781 P46782 P46783 P47914 P49207 P49458 P50914 P51571 P60059 P60468 P60866 P61009 P61011 P61247 P61254 P61313 P61353 P61513 P61619 P61927 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62424 P62701 P62750 P62753 P62829 P62841 P62847 P62851 P62854 P62857 P62861 P62888 P62891 P62899 P62906 P62910 P62913 P62917 P62945 P62979 P62987 P63173 P63220 P67812 P83731 P83881 P84098 Q02543 Q02878 Q07020 Q15005 Q15629 Q6P5R6 Q71UM5 Q8TD47 Q92901 Q969Q0 Q96EH5 Q96L21 Q9BY50 Q9H9S3 Q9UHB9 Q9UNL2 Q9UNX3 Q9Y3U8 Q9Y5M8 Q9Y6A9	BBC1 CCG2 D11S2243E D6S218E DDOST DXS648E EC45 FAU FTE1 KIAA0102 KIAA0115 LAMBR LAMR1 MFTL MPS1 NEDD6 OST48 QM RIG RPL1 RPL10 RPL10A RPL10L RPL11 RPL12 RPL13 RPL13A RPL14 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL22L1 RPL23 RPL23A RPL24 RPL26 RPL26L1 RPL26P1 RPL27 RPL27A RPL28 RPL29 RPL3 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36A RPL36AL RPL37 RPL37A RPL38 RPL39 RPL39L RPL39L1 RPL3L RPL4 RPL41 RPL44 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL9P7 RPL9P8 RPL9P9 RPLP0 RPLP1 RPLP2 RPN1 RPN2 RPP2 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA RRP1 SCAR SEC11A SEC11C SEC11L1 SEC11L3 SEC61A SEC61A1 SEC61A2 SEC61B SEC61G SPC12 SPC18 SPC21 SPC22 SPC25 SPCS1 SPCS2 SPCS3 SPCS4A SPCS4C SRP14 SRP19 SRP54 SRP68 SRP72 SRP9 SRPR SRPRA SRPRB SSR1 SSR2 SSR3 SSR4 SURF-3 SURF3 TRAM TRAM1 TRAPA TRAPB TRAPD TRAPG TXREB1 UBA52 UBA80 UBCEP1 UBCEP2	Homo sapiens (human)
STAT3 nuclear events downstream of ALK signaling	Cytokine receptor common subunit gamma DNA (cytosine-5)-methyltransferase 1 Histone acetyltransferase p300 Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 Hypoxia-inducible factor 1-alpha PR domain zinc finger protein 1 Paired amphipathic helix protein Sin3a Programmed cell death 1 ligand 1 Signal transducer and activator of transcription 3	O15379 O75626 P26358 P31785 P40763 Q09472 Q13547 Q16665 Q92769 Q96ST3 Q9NZQ7	AIM APRF B7H1 BHLHE78 BLIMP1 CD274 CXXC9 DNMT DNMT1 EP300 HDAC1 HDAC2 HDAC3 HIF1A IL2RG MOP1 P300 PASD8 PDCD1L1 PDCD1LG1 PDL1 PRDM1 RPD3L1 SIN3A STAT3	Homo sapiens (human)
STAT5 Activation	Fms-related tyrosine kinase 3 ligand GRB2-associated-binding protein 2 Receptor-type tyrosine-protein kinase FLT3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein phosphatase non-receptor type 11	P36888 P42229 P49771 P51692 Q06124 Q9UQC2	CD135 FLK2 FLT3 FLT3LG GAB2 KIAA0571 PTP2C PTPN11 SHPTP2 STAT5 STAT5A STAT5B STK1	Homo sapiens (human)
STAT5 activation downstream of FLT3 ITD mutants	Bcl-2-like protein 1 Cyclin-dependent kinase inhibitor 1 GRB2-associated-binding protein 2 Growth factor receptor-bound protein 2 NADPH oxidase 4 Receptor-type tyrosine-protein kinase FLT3 Serine/threonine-protein kinase pim-1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein phosphatase non-receptor type 11	P11309 P36888 P38936 P42229 P51692 P62993 Q06124 Q07817 Q9NPH5 Q9UQC2	ASH BCL2L BCL2L1 BCLX CAP20 CD135 CDKN1 CDKN1A CIP1 FLK2 FLT3 GAB2 GRB2 KIAA0571 MDA6 NOX4 PIC1 PIM1 PTP2C PTPN11 RENOX SDI1 SHPTP2 STAT5 STAT5A STAT5B STK1 WAF1	Homo sapiens (human)
STAT6-mediated induction of chemokines	Serine/threonine-protein kinase TBK1 Signal transducer and activator of transcription 6 Stimulator of interferon genes protein	P42226 Q86WV6 Q9UHD2	ERIS MITA NAK STAT6 STING STING1 TBK1 TMEM173	Homo sapiens (human)
STING mediated induction of host immune responses	Cyclic GMP-AMP synthase E3 ubiquitin-protein ligase TRIM21 Gamma-interferon-inducible protein 16 Probable ATP-dependent RNA helicase DDX41 Stimulator of interferon genes protein	P19474 Q16666 Q86WV6 Q8N884 Q9UJV9	ABS C6orf150 CGAS DDX41 ERIS IFI16 IFNGIP1 MB21D1 MITA RNF81 RO52 SSA1 STING STING1 TMEM173 TRIM21	Homo sapiens (human)
SUMO is conjugated to E1 (UBA2:SAE1)	SUMO-activating enzyme subunit 1 SUMO-activating enzyme subunit 2 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3	P55854 P61956 P63165 Q9UBE0 Q9UBT2	AOS1 SAE1 SAE2 SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SUA1 SUMO1 SUMO2 SUMO3 UBA2 UBL1 UBLE1A UBLE1B	Homo sapiens (human)
SUMO is proteolytically processed	Sentrin-specific protease 1 Sentrin-specific protease 2 Sentrin-specific protease 5 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3	P55854 P61956 P63165 Q96HI0 Q9HC62 Q9P0U3	KIAA1331 SENP1 SENP2 SENP5 SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SUMO1 SUMO2 SUMO3 UBL1	Homo sapiens (human)
SUMO is transferred from E1 to E2 (UBE2I, UBC9)	RWD domain-containing protein 3 SUMO-activating enzyme subunit 1 SUMO-activating enzyme subunit 2 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3	P55854 P61956 P63165 P63279 Q9UBE0 Q9UBT2 Q9Y3V2	AOS1 RSUME RWDD3 SAE1 SAE2 SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SUA1 SUMO1 SUMO2 SUMO3 UBA2 UBC9 UBCE9 UBE2I UBL1 UBLE1A UBLE1B	Homo sapiens (human)
SUMOylation of DNA damage response and repair proteins	Aladin Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Centrin-2 Chromobox protein homolog 2 Chromobox protein homolog 8 Cohesin subunit SA-1 Cohesin subunit SA-2 DNA repair protein RAD52 homolog DNA repair protein XRCC4 DNA repair protein complementing XP-C cells Double-strand-break repair protein rad21 homolog E3 SUMO-protein ligase CBX4 E3 SUMO-protein ligase NSE2 E3 SUMO-protein ligase PIAS1 E3 SUMO-protein ligase PIAS4 E3 SUMO-protein ligase RanBP2 E3 ubiquitin-protein ligase HERC2 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 E3 ubiquitin-protein ligase RNF168 EP300-interacting inhibitor of differentiation 3 G/T mismatch-specific thymine DNA glycosylase Histone deacetylase 7 Mediator of DNA damage checkpoint protein 1 Non-structural maintenance of chromosomes element 1 homolog Non-structural maintenance of chromosomes element 3 homolog Non-structural maintenance of chromosomes element 4 homolog A Nuclear autoantigen Sp-100 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Poly [ADP-ribose] polymerase 1 Polycomb complex protein BMI-1 Polycomb group RING finger protein 2 Polyhomeotic-like protein 1 Polyhomeotic-like protein 2 Polyhomeotic-like protein 3 Protein PML Protein SEC13 homolog RecQ-like DNA helicase BLM Replication protein A 70 kDa DNA-binding subunit SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 Structural maintenance of chromosomes protein 1A Structural maintenance of chromosomes protein 3 Structural maintenance of chromosomes protein 5 Structural maintenance of chromosomes protein 6 Tumor suppressor ARF mRNA export factor RAE1	A8CG34 O00257 O15504 O60216 O75694 O75925 O95714 P09874 P12270 P23497 P27694 P29590 P35226 P35227 P35658 P37198 P38398 P41208 P43351 P49790 P49792 P54132 P55735 P55854 P57740 P61956 P63165 P63279 P78364 P78406 Q01831 Q06587 Q12769 Q13426 Q13569 Q14191 Q14676 Q14683 Q14781 Q5SRE5 Q7Z3B4 Q8IXK0 Q8IY18 Q8IYW5 Q8N140 Q8N1F7 Q8N2W9 Q8N3U4 Q8N726 Q8NDX5 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUI4 Q8WUM0 Q8WV22 Q8WVM7 Q92621 Q96HA1 Q96MF7 Q96MG7 Q96SB8 Q99496 Q99567 Q9BTX1 Q9BW27 Q9HC52 Q9NRG9 Q9NXX6 Q9UKX7 Q9UQE7	AAAS ADPRT ADRACALA BAM BAP1 BLM BMH BMI1 BRCA1 C10orf86 C7orf14 C8orf36 CAIN CALT CAN CBX2 CBX4 CBX8 CDKN2 CDKN2A CEN2 CETN2 CG1 CSPG6 D3S1231E DDXBP1 DING DXS423E EDR1 EDR2 EDR3 EID3 HCA4 HDAC7 HDAC7A HERC2 HIPI3 HR21 KIAA0023 KIAA0078 KIAA0095 KIAA0169 KIAA0170 KIAA0178 KIAA0197 KIAA0225 KIAA0594 KIAA0618 KIAA0791 KIAA0906 MAGEG1 MDC1 MEL18 MLM MMS21 MP44 MRNP41 MYL NDC1 NDNL2 NFBD1 NPAP60L NSMCE1 NSMCE2 NSMCE3 NSMCE4A NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 NXP1 PARP1 PC3 PCGF2 PCGF4 PCNT1 PH1 PH2 PH3 PHC1 PHC2 PHC3 PIAS1 PIAS4 PIASG PML POM121 POM121A POM121C PP8675 PPOL RAD21 RAD52 RAE1 RANBP2 RC1 RECQ2 RECQ3 RECQL2 RECQL3 REPA1 RING1 RING1A RING1B RNF1 RNF110 RNF168 RNF2 RNF51 RNF53 RNF71 RPA1 RPA70 SA1 SA2 SB1.8 SCC1 SCC3 SEC13 SEC13A SEC13L1 SEC13R SMC1 SMC1A SMC1L1 SMC3 SMC3L1 SMC5 SMC5L1 SMC6 SMC6L1 SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SP100 STAG1 STAG2 SUMO1 SUMO2 SUMO3 TDG TMEM48 TPR TRIM19 UBC9 UBCE9 UBE2I UBL1 WRN XPC XPCC XRCC4 ZNF144	Homo sapiens (human)
SUMOylation of DNA methylation proteins	Chromobox protein homolog 2 Chromobox protein homolog 8 DNA (cytosine-5)-methyltransferase 1 DNA (cytosine-5)-methyltransferase 3A DNA (cytosine-5)-methyltransferase 3B E3 SUMO-protein ligase CBX4 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 Polycomb complex protein BMI-1 Polycomb group RING finger protein 2 Polyhomeotic-like protein 1 Polyhomeotic-like protein 2 Polyhomeotic-like protein 3 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1	O00257 P26358 P35226 P35227 P63165 P63279 P78364 Q06587 Q14781 Q8IXK0 Q8NDX5 Q99496 Q9HC52 Q9UBC3 Q9Y6K1	AIM BAP1 BMI1 CBX2 CBX4 CBX8 CXXC9 DING DNMT DNMT1 DNMT3A DNMT3B EDR1 EDR2 EDR3 HIPI3 MEL18 PC3 PCGF2 PCGF4 PH1 PH2 PH3 PHC1 PHC2 PHC3 RC1 RING1 RING1A RING1B RNF1 RNF110 RNF2 RNF51 SMT3C SMT3H3 SUMO1 UBC9 UBCE9 UBE2I UBL1 ZNF144	Homo sapiens (human)
SUMOylation of DNA replication proteins	Aladin Aurora kinase A Aurora kinase B Baculoviral IAP repeat-containing protein 5 Borealin DNA topoisomerase 1 DNA topoisomerase 2-alpha DNA topoisomerase 2-beta E3 SUMO-protein ligase PIAS3 E3 SUMO-protein ligase PIAS4 E3 SUMO-protein ligase RanBP2 Inner centromere protein Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Proliferating cell nuclear antigen Protein SEC13 homolog Ran GTPase-activating protein 1 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 mRNA export factor RAE1	A8CG34 O14965 O15392 O15504 O75694 P11387 P11388 P12004 P12270 P35658 P37198 P46060 P49790 P49792 P55735 P55854 P57740 P61956 P63165 P63279 P78406 Q02880 Q12769 Q53HL2 Q5SRE5 Q7Z3B4 Q8N1F7 Q8N2W9 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96GD4 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NQS7 Q9NRG9 Q9UKX7 Q9Y6X2	AAAS ADRACALA AIK AIK2 AIM1 AIRK1 AIRK2 API4 ARK1 ARK2 AURA AURKA AURKB AYK1 BIRC5 BTAK C7orf14 CAIN CAN CDCA8 CG1 D3S1231E IAK1 IAP4 INCENP KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 KIAA1835 MP44 MRNP41 NDC1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNA PCNT1 PESCRG3 PIAS3 PIAS4 PIASG POM121 POM121A POM121C RAE1 RANBP2 RANGAP1 SD SEC13 SEC13A SEC13L1 SEC13R SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 STK1 STK12 STK15 STK5 STK6 SUMO1 SUMO2 SUMO3 TMEM48 TOP1 TOP2 TOP2A TOP2B TPR UBC9 UBCE9 UBE2I UBL1	Homo sapiens (human)
SUMOylation of RNA binding proteins	Aladin Chromobox protein homolog 2 Chromobox protein homolog 8 E3 SUMO-protein ligase CBX4 E3 SUMO-protein ligase RanBP2 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 Heterogeneous nuclear ribonucleoprotein K Heterogeneous nuclear ribonucleoproteins C1/C2 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleolar protein 58 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Polycomb complex protein BMI-1 Polycomb group RING finger protein 2 Polyhomeotic-like protein 1 Polyhomeotic-like protein 2 Polyhomeotic-like protein 3 Protein SEC13 homolog SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 mRNA export factor RAE1	A8CG34 O00257 O15504 O75694 P07910 P12270 P35226 P35227 P35658 P37198 P49790 P49792 P55735 P57740 P61956 P61978 P63165 P63279 P78364 P78406 Q06587 Q12769 Q14781 Q5SRE5 Q7Z3B4 Q8IXK0 Q8N1F7 Q8NDX5 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99496 Q99567 Q9BTX1 Q9BW27 Q9HC52 Q9NRG9 Q9UKX7 Q9Y2X3	AAAS ADRACALA BAP1 BMI1 C7orf14 CAIN CAN CBX2 CBX4 CBX8 CG1 D3S1231E DING EDR1 EDR2 EDR3 HIPI3 HNRNPC HNRNPK HNRPC HNRPK KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 MEL18 MP44 MRNP41 NDC1 NOL5 NOP5 NOP58 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PC3 PCGF2 PCGF4 PCNT1 PH1 PH2 PH3 PHC1 PHC2 PHC3 POM121 POM121A POM121C RAE1 RANBP2 RC1 RING1 RING1A RING1B RNF1 RNF110 RNF2 RNF51 SEC13 SEC13A SEC13L1 SEC13R SMT3B SMT3C SMT3H2 SMT3H3 SUMO1 SUMO2 TMEM48 TPR UBC9 UBCE9 UBE2I UBL1 ZNF144	Homo sapiens (human)
SUMOylation of SUMOylation proteins	Aladin E3 SUMO-protein ligase PIAS4 E3 SUMO-protein ligase RanBP2 E3 ubiquitin-protein ligase Topors Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein SEC13 homolog SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 mRNA export factor RAE1	A8CG34 O15504 O75694 P12270 P35658 P37198 P49790 P49792 P55735 P57740 P61956 P63165 P63279 P78406 Q12769 Q5SRE5 Q7Z3B4 Q8N1F7 Q8N2W9 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9NS56 Q9UKX7	AAAS ADRACALA C7orf14 CAIN CAN CG1 D3S1231E KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 LUN MP44 MRNP41 NDC1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 PIAS4 PIASG POM121 POM121A POM121C RAE1 RANBP2 SEC13 SEC13A SEC13L1 SEC13R SMT3B SMT3C SMT3H2 SMT3H3 SUMO1 SUMO2 TMEM48 TOPORS TP53BPL TPR UBC9 UBCE9 UBE2I UBL1	Homo sapiens (human)
SUMOylation of chromatin organization proteins	Aladin Chromobox protein homolog 2 Chromobox protein homolog 5 Chromobox protein homolog 8 Chromodomain-helicase-DNA-binding protein 3 DNA-binding protein SATB1 DNA-binding protein SATB2 E3 SUMO-protein ligase CBX4 E3 SUMO-protein ligase PIAS1 E3 SUMO-protein ligase RanBP2 E3 SUMO-protein ligase ZBED1 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 Histone H4 Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 4 Lethal(3)malignant brain tumor-like protein 2 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Polycomb complex protein BMI-1 Polycomb group RING finger protein 2 Polycomb protein SUZ12 Polyhomeotic-like protein 1 Polyhomeotic-like protein 2 Polyhomeotic-like protein 3 Protein SEC13 homolog SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 mRNA export factor RAE1	A8CG34 O00257 O15504 O75694 O75925 O96006 P12270 P35226 P35227 P35658 P37198 P45973 P49790 P49792 P55735 P55854 P56524 P57740 P61956 P62805 P63165 P63279 P78364 P78406 Q01826 Q06587 Q12769 Q12873 Q13547 Q14781 Q15022 Q5SRE5 Q7Z3B4 Q8IXK0 Q8N1F7 Q8NDX5 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q92769 Q969R5 Q96HA1 Q99496 Q99567 Q9BTX1 Q9BW27 Q9HC52 Q9NRG9 Q9UKX7 Q9UPW6	AAAS ADRACALA ALTE BAP1 BMI1 C7orf14 CAIN CAN CBX2 CBX4 CBX5 CBX8 CG1 CHD3 CHET9 D3S1231E DDXBP1 DING DREF EDR1 EDR2 EDR3 H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HDAC1 HDAC2 HDAC4 HIPI3 HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H4 HIST2H4A HIST2H4B HIST4H4 HP1A JJAZ1 KIAA0023 KIAA0095 KIAA0160 KIAA0169 KIAA0197 KIAA0225 KIAA0288 KIAA0618 KIAA0785 KIAA0791 KIAA0906 KIAA1034 L3MBTL2 MEL18 MP44 MRNP41 NDC1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PC3 PCGF2 PCGF4 PCNT1 PH1 PH2 PH3 PHC1 PHC2 PHC3 PIAS1 POM121 POM121A POM121C RAE1 RANBP2 RC1 RING1 RING1A RING1B RNF1 RNF110 RNF2 RNF51 RPD3L1 SATB1 SATB2 SEC13 SEC13A SEC13L1 SEC13R SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SUMO1 SUMO2 SUMO3 SUZ12 TMEM48 TPR TRAMP UBC9 UBCE9 UBE2I UBL1 ZBED1 ZNF144 hDREF	Homo sapiens (human)
SUMOylation of immune response proteins	E3 SUMO-protein ligase PIAS3 E3 SUMO-protein ligase PIAS4 E3 ubiquitin-protein ligase Topors Inhibitor of nuclear factor kappa-B kinase subunit epsilon Interferon-induced, double-stranded RNA-activated protein kinase NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p100 subunit SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 3 Transcription factor p65	P19525 P25963 P55854 P63165 P63279 Q00653 Q04206 Q14164 Q8N2W9 Q9NS56 Q9Y6K9 Q9Y6X2	EIF2AK2 FIP3 IKBA IKBKE IKBKG IKKE IKKI KIAA0151 LUN LYT10 MAD3 NEMO NFKB2 NFKB3 NFKBI NFKBIA PIAS3 PIAS4 PIASG PKR PRKR RELA SMT3A SMT3C SMT3H1 SMT3H3 SUMO1 SUMO3 TOPORS TP53BPL UBC9 UBCE9 UBE2I UBL1	Homo sapiens (human)
SUMOylation of intracellular receptors	Androgen receptor E3 SUMO-protein ligase PIAS1 E3 SUMO-protein ligase PIAS3 E3 SUMO-protein ligase PIAS4 Estrogen receptor Glucocorticoid receptor Histone deacetylase 4 Mineralocorticoid receptor Nuclear receptor ROR-alpha Nuclear receptor subfamily 2 group C member 1 Nuclear receptor subfamily 4 group A member 2 Oxysterols receptor LXR-beta Peroxisome proliferator-activated receptor alpha Peroxisome proliferator-activated receptor gamma Progesterone receptor Retinoic acid receptor RXR-alpha Retinoic acid receptor alpha SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 Steroidogenic factor 1 Thyroid hormone receptor beta Vitamin D3 receptor	O75925 P03372 P04150 P06401 P08235 P10275 P10276 P10828 P11473 P13056 P19793 P35398 P37231 P43354 P55055 P55854 P56524 P61956 P63165 P63279 Q07869 Q13285 Q8N2W9 Q9Y6X2	AD4BP AR DDXBP1 DHTR ERBA2 ESR ESR1 FTZF1 GRL HDAC4 KIAA0288 LXRB MCR MLR NER NOT NR1A2 NR1B1 NR1C1 NR1C3 NR1F1 NR1H2 NR1I1 NR2B1 NR2C1 NR3A1 NR3C1 NR3C2 NR3C3 NR3C4 NR4A2 NR5A1 NURR1 PGR PIAS1 PIAS3 PIAS4 PIASG PPAR PPARA PPARG RARA RORA RXRA RZRA SF1 SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SUMO1 SUMO2 SUMO3 THR1 THRB TINUR TR2 UBC9 UBCE9 UBE2I UBL1 UNR VDR	Homo sapiens (human)

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