GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **251 - 275** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
IRS-related events triggered by IGF1R	Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin-like growth factor 1 receptor Insulin-like growth factor I Insulin-like growth factor II	F1MAL5 P01346 P08025 P24062 P35570	Igf-1 Igf-2 Igf1 Igf1r Igf2 Irs-1 Irs1 Irs2	Rattus norvegicus (Norway rat)
Inhibition of TSC complex formation by PKB	Hamartin RAC-beta serine/threonine-protein kinase Tuberin	P47197 P49816 Q9Z136	Akt2 Tsc1 Tsc2	Rattus norvegicus (Norway rat)
Synaptic adhesion-like molecules	Disks large homolog 1 Disks large homolog 3 Disks large homolog 4 Flotillin-1 Flotillin-2 Glutamate receptor 1 Glutamate receptor 3 Glutamate receptor 4 Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2A Glutamate receptor ionotropic, NMDA 2B Glutamate receptor ionotropic, NMDA 2C Glutamate receptor ionotropic, NMDA 2D Leucine-rich repeat and fibronectin type III domain-containing protein 1 Leucine-rich repeat and fibronectin type-III domain-containing protein 2 Leucine-rich repeat and fibronectin type-III domain-containing protein 3 Leucine-rich repeat and fibronectin type-III domain-containing protein 4 Receptor-type tyrosine-protein phosphatase F Receptor-type tyrosine-protein phosphatase S Reticulon-3 protein-tyrosine-phosphatase	A0A8I6A6R5 B0BNK7 D4ABX8 P0C7J6 P19490 P19492 P19493 P31016 P35439 Q00959 Q00960 Q00961 Q460M5 Q62645 Q62696 Q62936 Q64604 Q64605 Q6RJR6 Q9Z1E1 Q9Z2S9	Dlg1 Dlg3 Dlg4 Dlgh1 Dlgh3 Dlgh4 Flot1 Flot2 GluA1 GluA3 GluN2D Glur1 Glur3 Glur4 Gria1 Gria3 Gria4 Grin1 Grin2a Grin2b Grin2c Grin2d Lar Lrfn1 Lrfn2 Lrfn3 Lrfn4 Nmdar1 Psd95 Ptprd Ptprf Ptprs Reg1 Reg2 Rtn3 Salm1 Salm2 Salm3 Salm4	Rattus norvegicus (Norway rat)
Regulation of FZD by ubiquitination	Frizzled-4 Frizzled-5 Frizzled-6 Frizzled-8 Leucine-rich repeat-containing G protein-coupled receptor 6 Leucine-rich repeat-containing G-protein coupled receptor 5 Low-density lipoprotein receptor-related protein Low-density lipoprotein receptor-related protein Polyubiquitin-B Polyubiquitin-C Protein Wnt R-spondin 1 R-spondin 2 R-spondin 3 R-spondin 4 RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1	A0A0G2K0H3 A0A8I5ZKZ0 A0A8I6A5Y3 A0A8I6AML0 A0A8I6G721 A7LKE6 D3ZBD1 D3ZJU9 D3ZN39 D4AC13 D4ACX0 F1M077 G3V6L1 I7GAZ6 P0CG51 P62982 Q498S8 Q63429 Q8CHL0 Q9QZH0	Fzd4 Fzd5 Fzd6 Fzd8 LOC100360645 Lgr5 Lgr6 Lrp5 Lrp6 R-spondin2 Rnf43 Rps27a Rspo1 Rspo2 Rspo3 Rspo4 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Usp8 Wnt3a Znrf3	Rattus norvegicus (Norway rat)
RNA polymerase II transcribes snRNA genes	Arsenite-resistance protein 2 Ccnk protein Cyclin T2 Cyclin-T1 Cyclin-dependent kinase 7 (Fragment) Cyclin-dependent kinase 9 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase subunit beta DNA-directed RNA polymerase subunit DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Elongation factor for RNA polymerase II 2 Elongation factor for RNA polymerase II General transcription factor IIE subunit 1 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Integrator complex subunit 10 Integrator complex subunit 11 Integrator complex subunit 12 Integrator complex subunit 13 Integrator complex subunit 14 Integrator complex subunit 1 Integrator complex subunit 2 Integrator complex subunit 3 Integrator complex subunit 4 Integrator complex subunit 5 Integrator complex subunit 6 Integrator complex subunit 7 Integrator complex subunit 8 Integrator complex subunit 9 Interactor of little elongation complex ELL subunit 1 Interactor of little elongation complex ELL subunit 2 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 PCF11 cleavage and polyadenylation factor subunit POU domain protein POU domain, class 2, transcription factor 1 (Fragment) Phosphorylated adapter RNA export protein RNA polymerase II elongation factor ELL3 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 RNA polymerase II subunit B1 CTD phosphatase Rpap2 RNA polymerase II subunit C RNA polymerase II subunit D RNA polymerase II subunit I RNA polymerase II subunit J Regulation of nuclear pre-mRNA domain containing 2 Regulation of nuclear pre-mRNA domain-containing protein Regulation of nuclear pre-mRNA domain-containing protein SOSS complex subunit B1 SOSS complex subunit B2 Small nuclear RNA activating complex, polypeptide 1 Small nuclear RNA activating complex, polypeptide 4 TATA-box binding protein associated factor 13 TATA-box binding protein associated factor 5 TATA-box-binding protein Transcription elongation factor SPT4 Transcription elongation factor SPT5 Transcription factor Sp1 Transcription initiation factor IIA subunit 1 Transcription initiation factor IIA subunit 2 Transcription initiation factor IIB Transcription initiation factor IIE subunit beta Transcription initiation factor TFIID subunit 11 Transcription initiation factor TFIID subunit 6 Transcription initiation factor TFIID subunit 8 Transcription initiation factor TFIID subunit 9 Zinc finger CCCH type containing 8 snRNA-activating protein complex subunit 2 snRNA-activating protein complex subunit 3	A0A096MJ28 A0A0G2JXM2 A0A0G2K0V1 A0A0G2K8E5 A0A8I5ZQE1 A0A8I5ZR84 A0A8I5ZWB2 A0A8I5ZXX1 A0A8I6A150 A0A8I6A2X2 A0A8I6A4F7 A0A8I6A5G5 A0A8I6A799 A0A8I6A9T0 A0A8I6AHR3 A0A8I6AM26 A0A8I6AP01 A0A8I6AXL7 A0A8I6G5J7 A0A8I6GJT1 A1L1L5 B0BNE2 B1WC40 B2RYQ7 B5DEK0 B5DEM7 D3ZCP9 D3ZGL6 D3ZH66 D3ZIQ8 D3ZQI0 D3ZTW1 D3ZUT9 D4A5A6 D4AAU4 D4ADS6 F1LYZ6 F1M8D7 F7ES94 F7FCG9 G3V8Y5 G3V992 M0RBH0 M0RCG9 O08949 O08950 O88828 P31503 P51952 P62489 P62916 Q01714 Q01750 Q3MHC2 Q3SWT1 Q4KLK9 Q56A27 Q5BK68 Q5BKE0 Q5EB90 Q5FVP2 Q5I0E6 Q5U1X0 Q5XFX8 Q63068 Q63801 Q641Z4 Q66H58 Q68FR3 Q68FX5 Q6AY96	AABR07064983.1 AC109542.1 Cak Cak1 Cbp20 Cbp80 Ccnk Ccnt1 Ccnt2 Cdk7 Cdk9 Cpsf3l Ell Ell2 Ell3 Gtf2a1 Gtf2a2 Gtf2b Gtf2e1 Gtf2e2 Gtf2f1 Gtf2f2 Ice1 Ice2 Ints1 Ints10 Ints11 Ints12 Ints13 Ints14 Ints2 Ints3 Ints4 Ints5 Ints6 Ints7 Ints8 Ints9 LOC120098305 Mo15 Nabp1 Nabp2 Narg2 Ncbp1 Ncbp2 Obfc2a Obfc2b Oct-1 Otf-1 Otf1 Pcf11 Phax Phf22 Polr2a Polr2b Polr2c Polr2d Polr2e Polr2f Polr2g Polr2i Polr2j Pou2f1 Pou2f2 RGD1562299 Rap30 Rnuxa Rpap2 Rprd1a Rprd1b Rprd2 Snapc1 Snapc2 Snapc3 Snapc4 Sp1 Srrt Ssb1 Ssb2 Ssu72 Supt4h1 Supt5h Taf11 Taf13 Taf2e Taf2g Taf5 Taf6 Taf8l1 Taf9 Tafii31 Tbp Vwa9 Zc3h8	Rattus norvegicus (Norway rat)
Acrosome Reaction and Sperm:Oocyte Membrane Binding	Acrosin CD9 antigen IZUMO family member 2 IZUMO family member 3 IZUMO family member 4 Izumo sperm-egg fusion protein 1	A0A8I5ZSN1 D3ZRD5 M0R6I5 P29293 P40241 Q6AY06	Acr Cd9 Izumo1 Izumo2 Izumo3 Izumo4	Rattus norvegicus (Norway rat)
Sodium/Calcium exchangers	Calmodulin-3 Mitochondrial sodium/calcium exchanger protein Sodium/calcium exchanger 1 Sodium/calcium exchanger 2 Sodium/calcium exchanger 3 Sodium/potassium/calcium exchanger 1 Sodium/potassium/calcium exchanger 2 Sodium/potassium/calcium exchanger 3 (Fragment) Solute carrier family 24 member 4 Solute carrier family 24 member 5 Sorcin	A0A0G2K3S9 A0A8I5Y9M9 A0A8I6GB53 O54701 P0DP31 P48768 P70549 Q01728 Q6AXS0 Q9EPQ0 Q9QZM6	CaMIII Calm3 Cam3 Camc Nckx1 Nckx2 Nckx3 Nckx6 Nclx Ncx1 Ncx2 Ncx3 Slc24a1 Slc24a2 Slc24a3 Slc24a4 Slc24a5 Slc24a6 Slc8a1 Slc8a2 Slc8a3 Slc8b1 Sri	Rattus norvegicus (Norway rat)
YAP1- and WWTR1 (TAZ)-stimulated gene expression	Histone acetyltransferase T-box transcription factor TBX5 TEA domain transcription factor 1 TEA domain transcription factor 2 Transcriptional coactivator YAP1 Transcriptional enhancer factor TEF-3 Transcriptional enhancer factor TEF-5 WW domain containing transcription regulator 1	A0A0G2K2S9 A0A8I5Y222 A0A8I5ZMT2 A0A8I6AIX9 A0A8I6GMF8 Q2EJA0 Q4V7E6 Q5I2P1	Kat2b Tbx5 Tead1 Tead2 Tead3 Tead4 Wwtr1 Yap Yap1 Yap65	Rattus norvegicus (Norway rat)
Metabolism of steroid hormones	Steryl-sulfatase	P15589	Sts	Rattus norvegicus (Norway rat)
Downregulation of TGF-beta receptor signaling	BMP and activin membrane-bound inhibitor homolog E3 ubiquitin-protein ligase Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 7 Polyubiquitin-B Polyubiquitin-C Prostate transmembrane protein, androgen induced 1 Serine-threonine kinase receptor-associated protein TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein protein-tyrosine-phosphatase	A0A8I5Y0P5 A0A8I6A5Y3 A0A8I6AFY1 M0RCH9 O70436 O88406 P0CG51 P17246 P38438 P62982 P80204 P84025 Q5XIG8 Q63429 Q91XN4	Bambi LOC100360645 Madh2 Madh3 Madh7 Mtmr4 Pmepa1 Rps27a Smad2 Smad3 Smad7 Smurf2 Strap Tgfb1 Tgfbr1 Tgfbr2 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Unrip	Rattus norvegicus (Norway rat)
MAPK3 (ERK1) activation	Cyclin-dependent kinase 1 Dual specificity mitogen-activated protein kinase kinase 1 Interleukin-6 receptor subunit alpha Interleukin-6 receptor subunit beta Interleukin-6 Mitogen-activated protein kinase 3 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11	A0A8I6AM23 D3ZD03 P20607 P21708 P22273 P39951 P40190 P41499 Q01986 Q62689	Cdc2 Cdc2a Cdk1 Cdkn1 Erk1 Il-6 Il6 Il6r Il6ra Il6st Jak1 Jak2 Map2k1 Mapk3 Mek1 Prkm3 Prkmk1 Ptpn11 Tyk2	Rattus norvegicus (Norway rat)
ATF6B (ATF6-beta) activates chaperones	Activating transcription factor 6 beta Membrane-bound transcription factor site-1 protease	F7ERH6 Q9WTZ3	Atf6b Mbtps1 S1p Ski1	Rattus norvegicus (Norway rat)
The canonical retinoid cycle in rods (twilight vision)	Cytochrome P450 4V2 LRRGT00111 Lecithin retinol acyltransferase Myosin VIIA Receptor for retinol uptake STRA6 Retinaldehyde binding protein 1 Retinoid isomerohydrolase Retinol binding protein 3 Retinol dehydrogenase 10 Retinol dehydrogenase 12 Retinol-binding protein 1 Retinol-binding protein 4 Rhodopsin Transthyretin	A0A8I5ZWB0 A2RRT9 D3Z956 D3ZEP9 G3V8Q4 O70276 P02696 P02767 P04916 P51489 Q4QR83 Q6TUD3 Q80ZF7 Q9JI61	Cyp4v2 Cyp4v3 Lrat Myo7a Rbp-1 Rbp1 Rbp3 Rbp4 Rdh10 Rdh11 Rdh12 Rho Rlbp1 Rpe65 Stra6 Tt Ttr	Rattus norvegicus (Norway rat)
Nuclear signaling by ERBB4	Estrogen receptor Gamma-secretase subunit APH-1 Gamma-secretase subunit PEN-2 Nicastrin Presenilin-1 Presenilin-2 Proto-oncogene tyrosine-protein kinase Src Signal transducer and activator of transcription 5A Transcriptional coactivator YAP1 WW domain-containing oxidoreductase	A0A8I6AEI3 F7EYZ3 O88777 P06211 P97887 Q2EJA0 Q62771 Q6QI68 Q8CGU6 Q9WUD9	AABR07043897.1 Aph1a Esr Esr1 Estr Mgf Ncstn Nr3a1 Ps2 Psen1 Psen2 Psenen Psnl1 Psnl2 Src Stat5a Wwox Yap Yap1 Yap65	Rattus norvegicus (Norway rat)
PD-1 signaling	CD274 molecule Histocompatibility 2, class II antigen E alpha Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MHC class II beta chain Programmed cell death 1 ligand 2 Programmed cell death 1 Proto-oncogene tyrosine-protein kinase LCK RT1 class II, H alpha RT1 class II, locus Hb, pseudogene 1 Rano class II histocompatibility antigen, B alpha chain Rano class II histocompatibility antigen, B-1 beta chain Rano class II histocompatibility antigen, D-1 beta chain T cell receptor beta, variable 16 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 Tyrosine-protein kinase CSK Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6	A0A023IKK2 A0A8I5ZPF9 A0A8I6A4Z0 A0A8I6AAG4 A0A8I6G8N5 A0A8I6GKC3 D3ZIN8 D3ZND8 D4AAV6 D4AE25 M0R576 M0RE10 P05540 P18211 P19377 P20037 P29826 P32577 P41499 P81718 Q01621 Q64159 Q6MG98 Q6MGB1	AABR07044416.1 Arrb2-ps Cd247 Cd274 Cd3d Cd3e Cd3g Cd4 Csk DA1 Db2 ENSRNOG00000065769 ENSRNOG00000065908 ENSRNOG00000065955 ENSRNOG00000070909 H2-Ea Hla-dma Hla-dmb LOC100911800 Lck Pdcd1 Pdcd1lg2 Psmb9 Ptph6 Ptpn11 Ptpn6 RT1-Ba RT1-Bb RT1-DOb RT1-Da RT1-Db1 RT1-Db2 RT1-Ha RT1-Hb-ps1 T3d Tap1 Tap2 Tesb Trbv16	Rattus norvegicus (Norway rat)
Biosynthesis of DHA-derived SPMs	Polyunsaturated fatty acid lipoxygenase ALOX12 Polyunsaturated fatty acid lipoxygenase ALOX15 Prostaglandin G/H synthase 2	F1LQ70 P35355 Q02759	Alox12 Alox12l Alox15 Cox-2 Cox2 Ptgs2	Rattus norvegicus (Norway rat)
RHOBTB2 GTPase cycle	Actin, cytoplasmic 2 Alpha-actinin-1 Cullin-3 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heterogeneous nuclear ribonucleoprotein C Hsp90 co-chaperone Cdc37 Musashi RNA-binding protein 2 Pleckstrin homology domain interacting protein RNA-binding motif protein, X chromosome Rho-related BTB domain containing 2 Serine and arginine repetitive matrix 1 Serine/threonine kinase 38 Spliceosome RNA helicase Ddx39b T-complex protein 1 subunit beta T-complex protein 1 subunit eta T-complex protein 1 subunit zeta Thioredoxin-like protein 1 Transformer-2 protein homolog beta Tropomodulin 3 Twinfilin-1 Unconventional myosin-VI	A0A8I5ZV38 A0A8I6ACM8 A0A8I6AQW7 A0A8I6AR12 B5DF89 F1M3B3 F7ELS2 F7F0R0 G3V9Q4 G3V9R8 P34058 P62997 P63259 P82995 Q4V898 Q5BJV7 Q5RJR2 Q5XIM9 Q63413 Q63692 Q920J4 Q9Z1P2	Actg Actg1 Actn1 Bat1 Bat1a Cct2 Cct6a Cct7 Cctb Cdc37 Cul3 Ddx39b Hnrnpc Hnrpc Hsp84 Hsp86 Hsp90aa1 Hsp90ab1 Hspc3 Hspca Hspcb Msi2 Myo6 Phip Ptk9 Rbmx Rbmxrt Rhobtb2 Sfrs10 Srrm1 Stk38 Tmod3 Tra2b Trp Twf1 Txnl1 Uap56	Rattus norvegicus (Norway rat)
Synthesis of 15-eicosatetraenoic acid derivatives	Glutathione peroxidase 1 Glutathione peroxidase 2 Phospholipid hydroperoxide glutathione peroxidase Polyunsaturated fatty acid lipoxygenase ALOX15 Polyunsaturated fatty acid lipoxygenase ALOX15B Prostaglandin G/H synthase 2	P04041 P35355 P36970 P83645 Q02759 Q8K4F2	Alox12l Alox15 Alox15b Cox-2 Cox2 Gpx1 Gpx2 Gpx4 Ptgs2	Rattus norvegicus (Norway rat)
Signal regulatory protein family interactions	FYN-binding protein 1 Growth factor receptor-bound protein 2 Ig-like domain-containing protein Leukocyte surface antigen CD47 Protein-tyrosine kinase 2-beta Signal-regulatory protein alpha like 1 Signal-regulatory protein beta 2 Src kinase-associated phosphoprotein 2 TYRO protein tyrosine kinase-binding protein Tyrosine-protein phosphatase non-receptor type substrate 1-like Tyrosine-protein phosphatase non-receptor type substrate 1-like Tyrosine-protein phosphatase non-receptor type substrate 1	A0A0G2K068 A0A8I6GMF6 D3ZIE4 F1LW33 F1LY66 M0RAK5 P62994 P70600 P97710 P97829 Q6X9T7 Q920G0	AABR07008876.1 Ash Bit Cd47 Dap12 Fak2 Fyb Fyb1 Grb2 LOC100909964 Mfr Ptk2b Ptpns1 Pyk2 Scap2 Shps1 Sirp Sirpa Sirpal1 Sirpb2 Sirpd Skap2 Skap55r Tyrobp	Rattus norvegicus (Norway rat)
Glycerophospholipid catabolism	Glycerophosphocholine cholinephosphodiesterase ENPP6 Glycerophosphodiester phosphodiesterase 1 Patatin-like phospholipase domain containing 6	B0BND0 M0R715 Q9JL55	Enpp6 Gde1 Mir16 Pnpla6	Rattus norvegicus (Norway rat)
EPH-Ephrin signaling	EPH receptor A10 Ephrin A2 Ephrin A3 Ephrin A4 Ephrin B3 Ephrin type-A receptor 3 Ephrin type-A receptor 5 Ephrin type-A receptor 6 Ephrin type-A receptor 7 Ephrin type-B receptor 1 Ephrin type-B receptor 3 Ephrin type-B receptor 6 Ephrin-A1 Ephrin-A5 Ephrin-B1 receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase	A0A0G2JV56 D3ZBN3 D3ZDH4 D3ZEN1 D3ZH39 D3ZZK3 F1LX55 F1MA19 F1MAJ0 G3V7D4 M0RDA4 O08680 P09759 P0C0K7 P52796 P54757 P54758 P54759 P97553 P97605	Efna1 Efna2 Efna3 Efna4 Efna5 Efnb1 Efnb3 Ehk-1 Ehk-2 Ehk-3 Ehk2 Ehk3 Ekh1 Elk Epgl1 Epha1 Epha10 Epha2 Epha3 Epha4 Epha5 Epha6 Epha7 Ephb1 Ephb2 Ephb3 Ephb4 Ephb6 Eplg2 Eplg7 Epth2 LOC686310 Lerk1 Lerk2 Lerk7 Rek4 Rek7 Tyro4	Rattus norvegicus (Norway rat)
Transfer of LPS from LBP carrier to CD14	Lipopolysaccharide-binding protein Monocyte differentiation antigen CD14	Q63313 Q63691	Cd14 Lbp	Rattus norvegicus (Norway rat)
RAC2 GTPase cycle	ARF GTPase-activating protein GIT1 ARF GTPase-activating protein GIT2 Abl interactor 1 Abl-interactor 2 Active breakpoint cluster region-related protein Ankyrin repeat and LEM domain-containing protein 2 Armadillo repeat-containing X-linked protein 3 BAR/IMD domain-containing adapter protein 2-like 1 BRICK1 subunit of SCAR/WAVE actin nucleating complex Breakpoint cluster region protein CDC42 effector protein 4 Caveolin-1 Cdc42 effector protein 1 Cell division control protein 42 homolog Cell surface glycoprotein MUC18 Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein DEF6 guanine nucleotide exchange factor DEP domain containing 1B Dedicator of cyto-kinesis 3 Dedicator of cytokinesis 10 Dedicator of cytokinesis 2 Dedicator of cytokinesis 4 Delta(14)-sterol reductase LBR Desmoglein 2 Emerin Extended synaptotagmin-1 Granule associated Rac and RHOG effector 1 IQ motif containing GTPase activating protein 1 Integrin beta-1 MAGUK p55 subfamily member 7 MCF.2 cell line derived transforming sequence Membrane-associated progesterone receptor component 2 Metaxin-1 NCK associated protein 1 like NHS actin remodeling regulator Nck-associated protein 1 Neutrophil cytosol factor 2 Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 4 Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Phospholipase D2 Protein ERGIC-53 Protein diaphanous homolog 3 Proto-oncogene vav RNA binding motif protein 39 Rac GTPase-activating protein 1 Rac family small GTPase 2 Ragulator complex protein LAMTOR1 Ras-related protein Rab-7a Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 1 Rho GTPase activating protein 21 Rho GTPase activating protein 32 Rho GTPase activating protein 42 Rho GTPase-activating protein 17 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 Rho GTPase-activating protein SYDE1 SLIT and NTRK-like family, member 5 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase TAO3 Sorting and assembly machinery component 50 homolog Starch-binding domain-containing protein 1 Switching B-cell complex subunit SWAP70 TIAM Rac1 associated GEF 1 Transferrin receptor protein 1 Triple functional domain protein Vang-like protein Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein-associated protein B Wiskott-Aldrich syndrome protein family member non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase receptor protein-tyrosine kinase	A0A0G2JTR4 A0A0G2JU49 A0A0G2JVP1 A0A0G2JXJ0 A0A0G2JYR5 A0A0G2K344 A0A8I5ZLD3 A0A8I5ZNF3 A0A8I5ZNR8 A0A8I5ZPB5 A0A8I5ZRT6 A0A8I5ZS98 A0A8I6A1P8 A0A8I6A9Q4 A0A8I6AC12 A0A8I6ADN8 A0A8I6AEP6 A0A8I6AG90 A0A8I6AH32 A0A8I6APL5 A0A8I6APV4 A0A8I6GDA1 A0A8I6GLR6 A0A8J8XFB5 A0A8J8XIU8 A1A5P0 A7E3N2 B1WC33 B5DF62 D3ZBN3 D3ZCK4 D3ZKC8 D3ZRE7 D3ZUP5 D3ZYG0 D3ZZN9 D4A8H8 D4AA32 F1LVW7 F1LXF1 F1M0Z1 F1M4N6 F1M707 F1MAK3 G3V7Q7 M0R9U3 P09527 P0CAX5 P35465 P41350 P49134 P54100 P55161 P63025 P70498 P81128 Q3KR97 Q53UA7 Q5FVN1 Q5FWU0 Q5U2Y3 Q5XI73 Q5XID7 Q5XIU9 Q62737 Q62902 Q63190 Q63787 Q63788 Q63789 Q64303 Q66H91 Q6AXV4 Q6P791 Q7TP65 Q8CFN2 Q99376 Q99N37 Q9EPF2 Q9ERL1 Q9QZM5 Q9Z1X1 Q9Z269 Q9Z272	AABR07021955.1 Abi1 Abi2 Abr Ankle2 Arg357 Arhgap1 Arhgap17 Arhgap21 Arhgap26 Arhgap32 Arhgap35 Arhgap42 Arhgdia Armcx3 Baiap2l1 Bcr Borg5 Brk1 Cav Cav1 Cdc42 Cdc42ep1 Cdc42ep4 Cyba Cybb Cyfip1 Def6 Depdc1b Diaph3 Dock10 Dock2 Dock3 Dock4 Dsg2 Emd Epha2 Ergic53 Esyt1 Fam62a Garre1 Git1 Git2 Grlf1 Hem2 Iqgap1 Itgb1 Jik Lamtor1 Lbr Lem4 Lman1 Mbc2 Mcam Mcf2 Mpp7 Mtx1 Muc18 Nap1 Ncf1 Ncf2 Ncf4 Nckap1 Nckap1l Nhs Ophn1 P190A Pak1 Pak2 Pak4 Pgrmc2 Pik3ca Pik3r1 Pik3r2 Pik3r3 Pld2 Prex1 Rab7 Rab7a Rac2 Racgap1 Rbm39 Samm50 Slitrk5 Stbd1 Swap70 Syb3 Syde1 Taok3 Tfrc Tiam1 Trfr Trio Vamp3 Vangl1 Vapb Vav Vav1 Vav2 Vav3 Vrk2 Wasf2 p190ARHOGAP	Rattus norvegicus (Norway rat)
Opioid Signalling	Mu-type opioid receptor Pro-opiomelanocortin Proenkephalin-B	P01194 P06300 P33535	Oprm1 Pdyn Pomc Pomc2 Ror-b	Rattus norvegicus (Norway rat)
Cholesterol biosynthesis	3-hydroxy-3-methylglutaryl-coenzyme A reductase 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 Acetyl-CoA acetyltransferase, cytosolic Delta(14)-sterol reductase LBR Delta(24)-sterol reductase Diphosphomevalonate decarboxylase Farnesyl pyrophosphate synthase Geranylgeranyl pyrophosphate synthase Hydroxymethylglutaryl-CoA synthase, cytoplasmic Isopentenyl-diphosphate Delta-isomerase 1 Lanosterol 14-alpha demethylase Lanosterol synthase Methylsterol monooxygenase 1 Mevalonate kinase Phosphomevalonate kinase Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 Protein ARV Squalene monooxygenase Squalene synthase Sterol regulatory element-binding protein 1 Sterol regulatory element-binding protein 2 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating isopentenyl-diphosphate Delta-isomerase	A0A8I6AEP6 D3ZTJ1 D3ZVY0 O35532 O35760 P05369 P17256 P17425 P48450 P51639 P52020 P56720 Q02769 Q3T1I5 Q5BQE6 Q5PPL3 Q5RK24 Q5XI22 Q62904 Q62967 Q64654 Q66H88 Q6F596	AABR07021955.1 Acat2 Arv1 Cyp51 Cyp51a1 Dhcr24 Erg1 Fdft1 Fdps Ggps1 Hmgcr Hmgcs Hmgcs1 Hsd17b7 Idi1 Idi2l3 Lbr Lss Mpd Msmo1 Mvd Mvk Nsdhl Osc Plpp6 Pmvk RGD1564999 Sc4mol Sqle Srebf1 Srebf2 Srebp1	Rattus norvegicus (Norway rat)

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