GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **351 - 375** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Interleukin-23 signaling	Interleukin 12 receptor subunit beta 1 Interleukin 23 receptor Interleukin-12 subunit beta Interleukin-23 subunit alpha Protein disulfide-isomerase Signal transducer and activator of transcription 3 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase	D3ZD03 E9PSU7 E9PU71 F1LX96 P04785 P52631 Q62689 Q91Z84	IL12B Il12b Il12rb1 Il23a Il23r Jak2 P4hb Pdia1 Stat3 Tyk2	Rattus norvegicus (Norway rat)
B-WICH complex positively regulates rRNA expression	Actin, cytoplasmic 1 Bromodomain adjacent to zinc finger domain, 1B DNA-directed RNA polymerase I subunit RPA12 DNA-directed RNA polymerase I subunit RPA1 DNA-directed RNA polymerase I subunit RPA2 DNA-directed RNA polymerase subunit DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC5 ERCC excision repair 6, chromatin remodeling factor Glycogen synthase kinase-3 beta Histone H2A type 2-A Histone H2A.J Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H3.1 Histone H3.3 Histone H3 Histone H4 Histone acetyltransferase Histone acetyltransferase Myb-binding protein 1A Nucleolar RNA helicase 2 Protein DEK RNA polymerase I subunit E RNA polymerase I subunit G SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 Splicing factor 3b, subunit 1 TATA box-binding protein-associated factor RNA polymerase I subunit A TATA box-binding protein-associated factor RNA polymerase I subunit B TATA box-binding protein-associated factor RNA polymerase I subunit D TATA box-binding protein-associated factor, RNA polymerase I, subunit C TATA-box-binding protein Unconventional myosin-Ic histone acetyltransferase	A0A0G2JTU1 A0A0G2JXI9 A0A8I5Y222 A0A8I5ZQQ5 A0A8I5ZSA8 A0A8I5ZYY0 A0A8I6A2W1 A0A8I6A7P3 A0A8I6A9T0 A0A8I6AFW8 A0A8I6ALC2 A0A8I6AWT3 A0A8I6AXL7 A0A8I6G641 A0A8I6G659 A9UMV8 B0BN64 B0BNE2 D3ZJ08 D3ZVK7 D3ZXP3 D3ZYB7 D4ACM0 D4ACX5 D4ADE7 D4ADH7 G3V7T6 G3V9C7 M0RBH0 M0RBQ5 O35821 O54888 O54889 O88828 P0CC09 P18266 P60711 P62804 P84245 Q00729 Q3B7U2 Q3B8Q1 Q5M948 Q63355 Q6AXS3 Q6LED0 Q6MFY5 Q6P773	AC109542.1 Actb Baz1b Cd3eap Ddx21 Ddx21a Dek ENSRNOG00000062927 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 Ep300 Ercc6 Gsk3b H2ab3 H2ac10 H2ac18 H2ac4 H2afb3 H2afx H2aj H2ax H2az2 H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H3-3b H3.3b H3c13 H3f3b H4c16 H4c2 H4f16 H4ft Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist2h2aa3 Hist2h3c2 Hist4 Hist4h4 Josd3 Kat2a Kat2b LOC100365043 LOC100910200 LOC120097726 LOC120098305 LOC684797 Mybbp1a Myo1c Myr2 Polr1a Polr1b Polr1e Polr1f Polr1g Polr1h Polr2e Polr2f Rpa1 Rpa2 Rpo1-2 Rpo1-4 Sf3b1 Smarca5 Taf1a Taf1b Taf1c Taf1d Tbp Th2b Twistnb Znrd1	Rattus norvegicus (Norway rat)
Regulation of IFNG signaling	Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Protein inhibitor of activated STAT, 1 Signal transducer and activator of transcription 4 Small ubiquitin-related modifier 1 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 2	A0A0G2JX93 A0A8I6AJT7 A0A8I6AM23 D4A109 F7FHZ1 O88583 P01581 P35233 Q5I0H3 Q62689 Q9QX78	Cish3 Ifng Ifngr1 Ifngr2 Jak1 Jak2 Pias1 Ptpn2 Socs1 Socs3 Stat1 Stat4 Sumo1	Rattus norvegicus (Norway rat)
Aflatoxin activation and detoxification	Aflatoxin B1 aldehyde reductase member 2 Aflatoxin B1 aldehyde reductase member 3 Aminoacylase-1A Cytochrome P450 1A2 Cytochrome P450 2A3 Cytochrome P450 3A18 Cytochrome P450 3A1 Cytochrome P450 3A2 Cytochrome P450 3A9 Cytochrome P450 3A Dipeptidase 1 Dipeptidase 2 Dipeptidase 3 Glutathione hydrolase 1 proenzyme Glutathione hydrolase 5 proenzyme Glutathione hydrolase 6 Glutathione hydrolase 7 Microsomal glutathione S-transferase 1 Microsomal glutathione S-transferase 2 Microsomal glutathione S-transferase 3 N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)	A0A0G2K5K4 A0A8I5ZLK2 A0A8I6AAX9 P04799 P04800 P05183 P07314 P08011 P20812 P31430 P38918 P51538 Q5M872 Q5M876 Q5U2X4 Q64581 Q6AYS7 Q6IE08 Q8CG45 Q99MZ4 Q9QWE9	Acy1 Acy1a Acy3 Afar Afar2 Aiar Akr7a1 Akr7a2 Akr7a3 Cyp1a-2 Cyp1a2 Cyp2a-3 Cyp2a3 Cyp2a3a Cyp3a-1 Cyp3a-2 Cyp3a1 Cyp3a11 Cyp3a13 Cyp3a18 Cyp3a2 Cyp3a62 Cyp3a9 Dpep1 Dpep2 Dpep3 Ggt Ggt1 Ggt5 Ggt6 Ggt7 Ggtl3 Ggtla1 Gst12 Mgst1 Mgst2 Mgst3 Mgst3l1 Rdp	Rattus norvegicus (Norway rat)
Prednisone ADME	11-beta-hydroxysteroid dehydrogenase 1 11-beta-hydroxysteroid dehydrogenase type 2 ATP-dependent translocase ABCB1 Albumin Aldo-keto reductase family 1 member C21 Aldo-keto reductase family 1, member C1 Corticosteroid-binding globulin Cytochrome P450 3A18 Cytochrome P450 3A1 Cytochrome P450 3A2 Cytochrome P450 3A9 Cytochrome P450 3A UDP-glucuronosyltransferase 1-2 UDP-glucuronosyltransferase 1A3 UDP-glucuronosyltransferase 1A5 UDP-glucuronosyltransferase 2B15 UDP-glucuronosyltransferase 2B17 UDP-glucuronosyltransferase 2B1 UDP-glucuronosyltransferase 2B2 UDP-glucuronosyltransferase 2B37 UDP-glucuronosyltransferase 2B7 UDP-glucuronosyltransferase	A0A0G2K5K4 F1LTB8 P02770 P04800 P05183 P08541 P08542 P09875 P16232 P19488 P20720 P31211 P36511 P43245 P50233 P51538 Q3MHS3 Q62789 Q64581 Q64637 Q64638 Q6AYQ2	Abcb1 Akr1c1 Akr1c21 Alb Cbg Cyp3a-1 Cyp3a-2 Cyp3a1 Cyp3a11 Cyp3a13 Cyp3a18 Cyp3a2 Cyp3a62 Cyp3a9 Hsd11 Hsd11b1 Hsd11b2 Hsd11k Hsd17b5 Mdr1 Mdr1b Pgy1 RGD1559459 Serpina6 Udpgtr2 Ugt1 Ugt1a2 Ugt1a3 Ugt1a5 Ugt2b Ugt2b1 Ugt2b12 Ugt2b15 Ugt2b17 Ugt2b2 Ugt2b3 Ugt2b34l1 Ugt2b36 Ugt2b37 Ugt2b4 Ugt2b5 Ugt2b6 Ugt2b7 Ugt2b8	Rattus norvegicus (Norway rat)
Transport of fatty acids	Apolipoprotein D Epididymal-specific lipocalin-12 Lipocalin 9 Long-chain fatty acid transport protein 1 long-chain-fatty-acid--CoA ligase long-chain-fatty-acid--CoA ligase von Ebner gland protein 1 von Ebner gland protein 2	A0A8I6ADK2 B3EY83 D4A2B8 G3V7V3 P20289 P23593 P41244 P97849	Apod Fatp Fatp1 Lcn12 Lcn9 Slc27a1 Slc27a4 Slc27a6 Vegp Vegp1 Vegp2	Rattus norvegicus (Norway rat)
Citric acid cycle (TCA cycle)	Aconitate hydratase, mitochondrial Citrate synthase, mitochondrial Fumarate hydratase, mitochondrial Heat shock protein 75 kDa, mitochondrial Isocitrate dehydrogenase [NADP], mitochondrial Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial Malate dehydrogenase, mitochondrial Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Succinate dehydrogenase cytochrome b560 subunit, mitochondrial Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial proton-translocating NAD(P)(+) transhydrogenase	A0A8I6AIH6 A0A8I6AQG5 F1LM47 P04636 P13086 P14408 P21913 P41565 P56574 Q5XHZ0 Q641Z9 Q68FX0 Q6PCT8 Q8VHF5 Q920L2 Q99NA5 Q9ER34	Aco2 Cs Fh Fh1 Hsp75 Hspc5 Idh2 Idh3B Idh3a Idh3g Mdh2 Mor1 Nnt SUCLA2 SUCLG2 Sdh1 Sdha Sdhb Sdhc Sdhd Sucla2 Suclg1 Suclg2 Trap1	Rattus norvegicus (Norway rat)
CDC42 GTPase cycle	Active breakpoint cluster region-related protein ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 Breakpoint cluster region protein Caveolin-1 Cell division control protein 42 homolog Chimaerin DEF6 guanine nucleotide exchange factor DEP domain containing 1B Dedicator of cytokinesis 10 Dedicator of cytokinesis 11 Dedicator of cytokinesis 6 Dedicator of cytokinesis 7 Dedicator of cytokinesis 8 Delta(14)-sterol reductase LBR Dynamin-binding protein Ephexin-1 Epithelial cell transforming 2 FERM, ARHGEF and pleckstrin domain-containing protein 1 FYVE, RhoGEF and PH domain containing 1 FYVE, RhoGEF and PH domain containing 2 FYVE, RhoGEF and PH domain containing 3 FYVE, RhoGEF and PH domain-containing protein 4 Family with sequence similarity 13, member B Gem-interacting protein Guanine nucleotide exchange factor DBS Guanine nucleotide-binding protein subunit alpha-13 Intersectin-1 Kinectin 1 LOC687105 protein MCF.2 cell line derived transforming sequence Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 Pleckstrin homology and RhoGEF domain containing G1 Pleckstrin homology and RhoGEF domain containing G2 Pleckstrin homology and RhoGEF domain containing G3 Rac GTPase-activating protein 1 RalA-binding protein 1 Ras-specific guanine nucleotide-releasing factor 2 Rho GDP dissociation inhibitor beta Rho GDP dissociation inhibitor gamma Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 10 Rho GTPase activating protein 1 Rho GTPase activating protein 21 Rho GTPase activating protein 22 Rho GTPase activating protein 30 Rho GTPase activating protein 31 Rho GTPase activating protein 32 Rho GTPase activating protein 33 Rho GTPase activating protein 40 Rho GTPase activating protein 42 Rho GTPase activating protein 45 Rho GTPase activating protein 4 Rho GTPase activating protein 5 Rho GTPase activating protein 9 Rho GTPase-activating protein 17 Rho GTPase-activating protein 20 Rho GTPase-activating protein 24 Rho GTPase-activating protein 26 Rho GTPase-activating protein 27 Rho GTPase-activating protein 29 Rho GTPase-activating protein 35 Rho GTPase-activating protein 44 Rho GTPase-activating protein 7 Rho GTPase-activating protein SYDE1 Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 6 Rho guanine nucleotide exchange factor 9 SLIT-ROBO Rho GTPase activating protein 1 SLIT-ROBO Rho GTPase activating protein 3 SLIT-ROBO Rho GTPase-activating protein 2 Spermatogenesis associated 13 StAR-related lipid transfer domain containing 13 StAR-related lipid transfer domain containing 8 Synaptobrevin homolog YKT6 T-cell activation RhoGTPase activating protein TIAM Rac1 associated GEF 1 Triple functional domain protein Unconventional myosin-IXb Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3	A0A096MK16 A0A0G2JTR4 A0A0G2JTU0 A0A0G2JV16 A0A0G2JVF0 A0A0G2JVX3 A0A0G2JYR5 A0A0G2K3H2 A0A0G2K7N9 A0A0G2K860 A0A0G2KA11 A0A8I5ZKS6 A0A8I5ZL97 A0A8I5ZMG2 A0A8I5ZPB5 A0A8I5ZRJ5 A0A8I5ZRM9 A0A8I5ZS98 A0A8I5ZXI2 A0A8I6A4W2 A0A8I6A829 A0A8I6A9Q4 A0A8I6AC12 A0A8I6ADN8 A0A8I6AEP6 A0A8I6AL39 A0A8I6ANH8 A0A8I6AP97 A0A8I6APD0 A0A8I6APL5 A0A8I6APV4 A0A8I6AQA1 A0A8I6GDA1 A0A8I6GLR6 B2GUW2 D3Z9I3 D3ZA21 D3ZA46 D3ZCI3 D3ZCK4 D3ZU63 D3ZUD0 D3ZWB4 D3ZWF9 D3ZXG5 D3ZYG0 D3ZZN9 D4A1D2 D4A208 D4A5B9 D4A646 D4A987 D4A9G6 D4AA32 D4AE81 E9PT59 F1LQX4 F1LXF1 F1LYQ8 F1M0Z1 F1M287 F1M5M9 F1MAK3 F7EUE3 G3V9A0 M0R3X3 M0R4F8 O88387 P0CAX5 P41350 P81128 Q5BKC9 Q5EGY4 Q5PQJ5 Q5U2Z7 Q5XI73 Q5XXR3 Q62796 Q63358 Q63406 Q63744 Q63787 Q63788 Q6P720 Q6Q7Y5 Q6REY9 Q6TLK4 Q8CFN2 Q99JE4 Q99N37 Q9ES67 Q9QX73 Q9WVE9	AABR07021955.1 AABR07032856.1 Abr Arap1 Arap2 Arap3 Arhgap1 Arhgap10 Arhgap17 Arhgap20 Arhgap21 Arhgap22 Arhgap24 Arhgap26 Arhgap27 Arhgap29 Arhgap30 Arhgap31 Arhgap32 Arhgap33 Arhgap35 Arhgap4 Arhgap40 Arhgap42 Arhgap44 Arhgap45 Arhgap5 Arhgap7 Arhgap9 Arhgdia Arhgdib Arhgdig Arhgef10 Arhgef11 Arhgef12 Arhgef15 Arhgef16 Arhgef19 Arhgef25 Arhgef26 Arhgef5 Arhgef6 Arhgef9 Bcr Camgap1 Cav Cav1 Cdc42 Def6 Depdc1b Dlc1 Dnmbp Dock10 Dock11 Dock6 Dock7 Dock8 Ect2 Ehsh1 Fam13b Farp1 Fgd1 Fgd2 Fgd3 Fgd4 Geft Gmip Gna13 Grf2 Grlf1 Itsn Itsn1 Ktn1 LOC687105 Lbr Mcf2 Mcf2l Myo9b Myr5 Ngef Ophn1 Ost P190A Pik3r1 Pik3r2 Plekhg1 Plekhg2 Plekhg3 Prex1 Prex2 RGD1565043 Racgap1 Ralbp1 Rasgrf2 Rhogap Rich2 Spata13 Srgap1 Srgap2 Srgap3 Stard12 Stard13 Stard8 Syde1 Tagap Tiam1 Trio Tuba Vav2 Vav3 Ykt6 p190ARHOGAP	Rattus norvegicus (Norway rat)
Recycling pathway of L1	AP-2 complex subunit alpha-2 AP-2 complex subunit alpha AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Clathrin heavy chain 1 Clathrin light chain A Dihydropyrimidinase-related protein 2 Dynamin-1 Dynamin-2 Dynamin-3 Endophilin-A1 Ezrin Kinesin family member 4A Kinesin family member 4B Mitogen-activated protein kinase 1 Moesin Neural cell adhesion molecule L1 Protein numb homolog Proto-oncogene tyrosine-protein kinase Src Radixin	A0A8I6A4J2 A0A8I6GLI2 E9PSJ3 E9PT65 O35179 O35763 P08081 P11442 P18484 P21575 P31977 P39052 P47942 P62744 P62944 P63086 P84092 Q05695 Q08877 Q2LC84 Q9WUD9	Adtab Ap17 Ap2a1 Ap2a2 Ap2b1 Ap2m1 Ap2s1 Caml1 Clapb1 Claps2 Clta Cltc Dnm Dnm1 Dnm2 Dnm3 Dpysl2 Dyn2 Dyn3 Erk2 Ezr Kif4a Kif4b L1cam Mapk Mapk1 Msn Numb Prkm1 Rdx Sh3d2a Sh3gl2 Sh3p4 Src Vil2	Rattus norvegicus (Norway rat)
Beta oxidation of octanoyl-CoA to hexanoyl-CoA	Enoyl-CoA hydratase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P08503 P14604 Q60587 Q64428 Q9WVK7	Acadm Echs1 Had Hadh Hadha Hadhb Hadhsc Schad	Rattus norvegicus (Norway rat)
Regulation of RUNX3 expression and activity	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Core-binding factor subunit beta E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proto-oncogene tyrosine-protein kinase Src Runt-related transcription factor Transforming growth factor beta-1 proprotein Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein histone acetyltransferase	A0A0G2JSL0 A0A0G2K612 A0A0G2K7T0 A0A8I5Y0P5 A0A8I5ZM79 A0A8I5ZNE7 A0A8I6A5Y3 A0A8I6G5V3 A0A8I6G641 A0A8I6GMB2 B0BN93 F1LMQ3 F1LMZ8 F7FGV7 G3V6W6 G3V8G2 O88761 P0CG51 P17220 P17246 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q9JHW0 Q9WTV5 Q9WUD9 Q9Z2X3	Cbfb Ep300 LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Mdm2 Mecl1 Mss1 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psmf1 Ring12 Rps27a Runx3 Smurf1 Smurf2 Src Sug1 Tbp1 Tbp7 Tgfb1 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
RAC1 GTPase cycle	ARF GTPase-activating protein GIT1 ARF GTPase-activating protein GIT2 Abl interactor 1 Abl-interactor 2 Actin-binding protein WASF1 Active breakpoint cluster region-related protein Alsin Amphoterin-induced protein 2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 BAR/IMD domain-containing adapter protein 2-like 1 BAR/IMD domain-containing adapter protein 2 BRICK1 subunit of SCAR/WAVE actin nucleating complex Beta-chimaerin Breakpoint cluster region protein CDC42 effector protein 4 Caveolin-1 Cdc42 effector protein 1 Cell division control protein 42 homolog Cell surface glycoprotein MUC18 Chimaerin Citron rho-interacting kinase Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein Cytoplasmic FMR1-interacting protein DEF6 guanine nucleotide exchange factor DEP domain containing 1B Dedicator of cyto-kinesis 3 Dedicator of cytokinesis 10 Dedicator of cytokinesis 11 Dedicator of cytokinesis 2 Dedicator of cytokinesis 4 Dedicator of cytokinesis 5 Dedicator of cytokinesis 6 Dedicator of cytokinesis 7 Dedicator of cytokinesis 8 Delta(14)-sterol reductase LBR Emerin Ephexin-1 Epithelial cell transforming 2 Extended synaptotagmin-1 FERM domain containing kindlin 2 FERM, ARH/RhoGEF and pleckstrin domain protein 2 FERM, ARHGEF and pleckstrin domain-containing protein 1 FYVE, RhoGEF and PH domain containing 5 Family with sequence similarity 13, member A Family with sequence similarity 13, member B Formin-like 1 Gem-interacting protein Granule associated Rac and RHOG effector 1 Guanine nucleotide exchange factor DBS Guanine nucleotide-binding protein subunit alpha-13 IQ motif containing GTPase activating protein 1 IQ motif containing GTPase activating protein 2 IQ motif containing GTPase activating protein 3 Integrin beta-1 Kalirin Kinectin 1 MAGUK p55 subfamily member 7 MCF.2 cell line derived transforming sequence NADPH oxidase 1 NADPH oxidase 3 NADPH oxidase activator 1 NADPH oxidase organizer 1 NCK associated protein 1 like NHS actin remodeling regulator Nck-associated protein 1 Neutral amino acid transporter B(0) Neutrophil cytosol factor 2 Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 4 Nischarin Oligophrenin-1 Partitioning defective 6 homolog alpha Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 Phospholipase D1 Phospholipase D2 Pleckstrin homology and RhoGEF domain containing G1 Pleckstrin homology and RhoGEF domain containing G2 Pleckstrin homology and RhoGEF domain containing G3 Pleckstrin homology and RhoGEF domain containing G6 Protein diaphanous homolog 3 Protein jagged-1 Proto-oncogene vav RNA binding motif protein 39 Rac GTPase-activating protein 1 Ragulator complex protein LAMTOR1 RalA-binding protein 1 Ras-related C3 botulinum toxin substrate 1 Ras-related protein Rab-7a Ras-specific guanine nucleotide-releasing factor 2 Rho GDP dissociation inhibitor beta Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 10 Rho GTPase activating protein 12 Rho GTPase activating protein 1 Rho GTPase activating protein 21 Rho GTPase activating protein 22 Rho GTPase activating protein 23 Rho GTPase activating protein 25 Rho GTPase activating protein 30 Rho GTPase activating protein 31 Rho GTPase activating protein 32 Rho GTPase activating protein 33 Rho GTPase activating protein 42 Rho GTPase activating protein 45 Rho GTPase activating protein 4 Rho GTPase activating protein 5 Rho GTPase activating protein 9 Rho GTPase-activating protein 15 Rho GTPase-activating protein 17 Rho GTPase-activating protein 20 Rho GTPase-activating protein 24 Rho GTPase-activating protein 26 Rho GTPase-activating protein 27 Rho GTPase-activating protein 29 Rho GTPase-activating protein 35 Rho GTPase-activating protein 44 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 39 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 6 Rho guanine nucleotide exchange factor 7 SH3 domain-binding protein 1 SLIT-ROBO Rho GTPase activating protein 1 SLIT-ROBO Rho GTPase activating protein 3 SLIT-ROBO Rho GTPase-activating protein 2 SOS Ras/Rac guanine nucleotide exchange factor 1 SOS Ras/Rho guanine nucleotide exchange factor 2 Serine/threonine-protein kinase MRCK alpha Serine/threonine-protein kinase N1 Serine/threonine-protein kinase N2 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein kinase PAK 5 Serine/threonine-protein kinase TAO3 Spermatogenesis associated 13 Switching B-cell complex subunit SWAP70 Synapse defective Rho GTPase homolog 2 Synaptobrevin homolog YKT6 Synaptosomal-associated protein 23 T-cell activation RhoGTPase activating protein TIAM Rac1 associated GEF 1 TIAM Rac1 associated GEF 2 Transferrin receptor protein 1 Triple functional domain protein Tyrosine-protein kinase Unconventional myosin-IXb Vang-like protein Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 Vesicle-associated membrane protein 3 Wiskott-Aldrich syndrome protein family member Wiskott-Aldrich syndrome protein family member non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase receptor protein-tyrosine kinase	A0A096MK16 A0A0G2JTR4 A0A0G2JTU0 A0A0G2JV16 A0A0G2JVF0 A0A0G2JVP1 A0A0G2JVX3 A0A0G2JXJ0 A0A0G2JYR5 A0A0G2JYU6 A0A0G2K344 A0A0G2K3H2 A0A0G2K7N9 A0A0G2KA11 A0A8I5ZK89 A0A8I5ZKS6 A0A8I5ZL97 A0A8I5ZLD3 A0A8I5ZMC4 A0A8I5ZNF3 A0A8I5ZNR8 A0A8I5ZPB5 A0A8I5ZRM9 A0A8I5ZRT6 A0A8I5ZS98 A0A8I5ZXI2 A0A8I6A4W2 A0A8I6A829 A0A8I6A9Q4 A0A8I6AC12 A0A8I6ADN8 A0A8I6AEP6 A0A8I6AH32 A0A8I6AHL8 A0A8I6AM38 A0A8I6AN18 A0A8I6ANH8 A0A8I6AP97 A0A8I6APD0 A0A8I6APL5 A0A8I6APV4 A0A8I6AQA1 A0A8I6G699 A0A8I6GDA1 A0A8I6GLR6 A0A8J8XFB5 A0A8J8XIU8 A1A5P0 A7E3N2 A7E3N7 B0BN40 B1WC33 B5DF62 D3ZA02 D3ZA21 D3ZA46 D3ZBN3 D3ZCI3 D3ZCK4 D3ZCS4 D3ZFJ3 D3ZFK8 D3ZGL1 D3ZJ25 D3ZKC8 D3ZMS5 D3ZQ51 D3ZRE7 D3ZUD0 D3ZUP5 D3ZWB4 D3ZXG5 D3ZYG0 D4A208 D4A280 D4A3T0 D4A646 D4A8H8 D4A987 D4A9G6 D4AA32 D4ABR1 D4ACU5 D4AE81 E9PSL7 E9PT59 F1LQX4 F1LVD8 F1LVW7 F1LXF1 F1LYQ8 F1M0N1 F1M0Z1 F1M287 F1M2D4 F1M4N6 F1M5M9 F1M707 F1MAI3 F1MAK3 F7EUE3 G3V7Q7 G3V9A0 M0R3X3 M0R7F3 O08874 O54874 O55043 O70377 P09527 P0C5Y8 P0CAX5 P35465 P41350 P49134 P54100 P55161 P63025 P70496 P70498 P81128 P97924 Q03070 Q3KR97 Q4G017 Q53UA7 Q5BJU7 Q5BKC9 Q5EGY4 Q5FWU0 Q5PQJ5 Q5U2Y3 Q5U2Z7 Q5XI73 Q5XXR3 Q62737 Q62796 Q62829 Q63190 Q63358 Q63406 Q63433 Q63722 Q63744 Q63787 Q63788 Q63789 Q64303 Q66H91 Q672K1 Q6AYC5 Q6B4M5 Q6GMN2 Q6P720 Q6P791 Q6Q7Y5 Q6REY9 Q6RUV5 Q6TLK4 Q7TNJ4 Q8CFN2 Q99376 Q99JE4 Q99N37 Q9EPF2 Q9ERL1 Q9ES67 Q9QZM5 Q9WV87 Q9Z1X1 Q9Z272	AABR07021955.1 AABR07032856.1 Abi1 Abi2 Abl2 Abr Ali1 Als2 Amigo2 Arap1 Arap2 Arap3 Arg357 Arhgap1 Arhgap10 Arhgap12 Arhgap15 Arhgap17 Arhgap20 Arhgap21 Arhgap22 Arhgap23 Arhgap24 Arhgap25 Arhgap26 Arhgap27 Arhgap29 Arhgap3 Arhgap30 Arhgap31 Arhgap32 Arhgap33 Arhgap35 Arhgap4 Arhgap42 Arhgap44 Arhgap45 Arhgap5 Arhgap7 Arhgap9 Arhgdia Arhgdib Arhgef10 Arhgef11 Arhgef15 Arhgef19 Arhgef25 Arhgef39 Arhgef5 Arhgef6 Arhgef7 Baiap2 Baiap2l1 Bch Bcr Borg5 Brk1 CRIK Camgap1 Cav Cav1 Cdc42 Cdc42bpa Cdc42ep1 Cdc42ep4 Chn2 Cit Cyba Cybb Cyfip1 Cyfip2 Def6 Depdc1b Diaph3 Dlc1 Dock10 Dock11 Dock2 Dock3 Dock4 Dock5 Dock6 Dock7 Dock8 Duo Ect2 Emd Epha2 Esyt1 Fam13a Fam13b Fam62a Farp1 Farp2 Fermt2 Fgd5 Fmnl1 Garre1 Geft Git1 Git2 Gmip Gna13 Grf2 Grlf1 Hapip Hem2 Iqgap1 Iqgap2 Iqgap3 Itgb1 Jag1 Jik Kalrn Ktn1 Lamtor1 Lbr Mbc2 Mcam Mcf2 Mcf2l Mox1 Mpp7 Muc18 Myo9b Myr5 Nap1 Ncf1 Ncf2 Ncf4 Nckap1 Nckap1l Ngef Nhs Nisch Noh1 Nox1 Nox3 Noxa1 Noxo1 Ophn1 Ost P190A Pak1 Pak2 Pak3 Pak3bp Pak4 Pak5 Pak6 Pak7 Par-6a Par6a Pard6a Pik3ca Pik3r1 Pik3r2 Pik3r3 Pixb Pk428 Pkn Pkn1 Pkn2 Pld1 Pld2 Plekhg1 Plekhg2 Plekhg3 Plekhg6 Prex1 Prex2 Prk1 Prk2 Prkcl1 Prkcl2 RGD1565043 Rab7 Rab7a Rac Rac1 Racgap1 Ralbp1 Rasgrf2 Rbm39 Rhogap Rich2 Sh3bp1 Slc1a5 Snap23 Sos1 Sos2 Spata13 Srgap1 Srgap2 Srgap3 Stard12 Swap70 Syb3 Syde2 Tagap Taok3 Tfrc Tiam1 Tiam2 Trfr Trio Vamp3 Vangl1 Vav Vav1 Vav2 Vav3 Vrk2 Wasf1 Wasf2 Wasf3 Wave1 Ykt6 p190ARHOGAP	Rattus norvegicus (Norway rat)
Astrocytic Glutamate-Glutamine Uptake And Metabolism	Excitatory amino acid transporter 1 Excitatory amino acid transporter 2 Glutamine synthetase Sodium-coupled neutral amino acid symporter 1	P09606 P24942 P31596 Q9JM15	Ata1 Eaat1 Eaat2 Glns Glnt Glt1 Glul Sa2 Sat1 Slc1a2 Slc1a3 Slc38a1 Snat1	Rattus norvegicus (Norway rat)
Keratan sulfate biosynthesis	Aggrecan core protein Beta-1,4-galactosyltransferase 3 Beta-1,4-galactosyltransferase 4 Beta-1,4-galactosyltransferase 6 Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 Carbohydrate sulfotransferase 1 Carbohydrate sulfotransferase 5 Fibromodulin Hexosyltransferase Hexosyltransferase Hexosyltransferase Keratocan Lumican Osteomodulin Prolargin Solute carrier family 35 member D2 Sulfotransferase Type 2 lactosamine alpha-2,3-sialyltransferase UDP-GlcNAc	A0A0G2K3K5 A0A1W2Q5Z7 D3ZEF9 D3ZVD7 D3ZX31 D4A1T9 D4A2A5 D4A3H6 D4A9P8 M0R868 O88419 P07897 P50609 P51886 P61131 P61943 Q02734 Q11205 Q5RJQ0 Q66H69 Q66HH1 Q6P768 Q9EQP5 Q9Z1S7	Acan Agc Agc1 B3gnt2 B3gnt3 B3gnt4 B3gnt7 B4galt2 B4galt3 B4galt4 B4galt5 B4galt6 Chst1 Chst2 Chst5 Fmod Kera Lcn Ldc Lum Omd Prelp Siat10 Siat4b Siat4c Siat5 Siat6 Slc35d2 St3gal1 St3gal2 St3gal3 St3gal4 St3gal6	Rattus norvegicus (Norway rat)
Ion transport by P-type ATPases	ATPase 13A1 ATPase cation transporting 13A2 Calcium-transporting ATPase type 2C member 1 Calcium-transporting ATPase type 2C member 2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-3 Cardiac phospholamban Cation-transporting ATPase Cation-transporting ATPase Copper-transporting ATPase 1 Copper-transporting ATPase 2 FXYD domain-containing ion transport regulator 3 FXYD domain-containing ion transport regulator 4 FXYD domain-containing ion transport regulator 6 FXYD domain-containing ion transport regulator 7 PDZ domain-containing protein 11 Phospholemman Phospholipid-transporting ATPase IC Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Plasma membrane calcium-transporting ATPase 1 Plasma membrane calcium-transporting ATPase 3 Plasma membrane calcium-transporting ATPase 4 Potassium-transporting ATPase alpha chain 1 Potassium-transporting ATPase alpha chain 2 Potassium-transporting ATPase subunit beta Probable phospholipid-transporting ATPase IIB Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Sodium/potassium-transporting ATPase subunit alpha-1 Sodium/potassium-transporting ATPase subunit alpha-2 Sodium/potassium-transporting ATPase subunit alpha-3 Sodium/potassium-transporting ATPase subunit alpha-4 Sodium/potassium-transporting ATPase subunit beta-1 Sodium/potassium-transporting ATPase subunit beta-2 Sodium/potassium-transporting ATPase subunit beta-3 Sodium/potassium-transporting ATPase subunit gamma Sorcin	A0A0G2JWQ8 A0A1B0GWR9 A0A8I5Y9D1 A0A8I5Y9M9 A0A8I5ZVG5 A0A8I5ZXX6 A0A8I6A3Z6 A0A8I6A6I4 A0A8I6A9Z8 A0A8I6GI47 D3ZE62 D3ZN41 D4A4W5 D4A7K5 D4AA47 D4ABB8 F1M9L4 F1MA70 F1MAA4 G3V7I3 O08589 P06685 P06686 P06687 P07340 P08413 P09626 P0DP31 P11275 P11505 P11507 P11730 P13638 P15791 P18596 P18598 P54708 P59645 P59649 P61016 P70705 Q04679 Q63113 Q63377 Q64535 Q64541 Q64542 Q64566 Q64568 Q64578 Q8R4C1 Q91XV6	Atp10a Atp10b Atp10d Atp11a Atp11b Atp11c Atp12a Atp13a1 Atp13a2 Atp13a4 Atp13a5 Atp1a1 Atp1a2 Atp1a3 Atp1a4 Atp1al1 Atp1al2 Atp1b1 Atp1b2 Atp1b3 Atp1c Atp1g1 Atp2a1 Atp2a2 Atp2a3 Atp2b1 Atp2b3 Atp2b4 Atp2c1 Atp2c2 Atp4a Atp4b Atp7a Atp7b Atp8a1 Atp8a2 Atp8b1 Atp8b2 Atp8b3 Atp8b4 Atp9a Atp9b CaMIII Calm3 Cam3 Camc Camk2a Camk2b Camk2d Camk2g Fxyd1 Fxyd2 Fxyd3 Fxyd4 Fxyd6 Fxyd7 Hka Mnk Pdzd11 Php Pina Plm Pln Pmca3 Spca2 Sri Wnd	Rattus norvegicus (Norway rat)
Signaling by LTK	ALK and LTK ligand 1 ALK and LTK ligand 2 Activated CDC42 kinase 1 Growth factor receptor-bound protein 2 Insulin receptor substrate 1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase receptor	A0A0G2K344 A0A8I6GCV6 B2RZ42 D4A3T0 M0R9C8 P35570 P62994 Q5M824 Q5U2X5 Q63787 Q63788 Q9Z1L0	Ack1 Alkal1 Alkal2 Ash Fam150a Grb2 Irs-1 Irs1 LOC100910984 Ltk Pik3ca Pik3cb Pik3r1 Pik3r2 Shc1 Sos1 Tnk2	Rattus norvegicus (Norway rat)
Interferon alpha/beta signaling	ATP binding cassette subfamily E member 1 Importin subunit alpha-5 Importin subunit beta-1 Interferon 1ai1 Interferon 1ai2 Interferon 1ai3 Interferon alpha and beta receptor subunit 1 Interferon alpha and beta receptor subunit 2 Interferon alpha-1-like Interferon alpha-12-like Interferon alpha-12-like Interferon alpha-12-like Interferon alpha-12-like Interferon alpha-12-like Interferon alpha-1 Interferon beta Interferon regulatory factor 9 Polyubiquitin-B Polyubiquitin-C Ribonuclease L Signal transducer and activator of transcription 4 Signal transducer and activator of transcription Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase Tyrosine-protein kinase Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein	A0A0G2JX93 A0A7R8C3L7 A0A8I5ZN08 A0A8I5ZQE9 A0A8I5ZQR5 A0A8I6A4N8 A0A8I6A5Y3 A0A8I6AEQ7 A0A8I6AM23 A0A8I6AN84 A0A8I6ANZ6 A0A8I6GMD9 D3Z919 D3ZD03 D3ZD23 D3ZDS9 D3ZFH0 F7EYG9 G3V915 M0R8H7 O88583 P05011 P0CG51 P52296 P62982 P70499 P83953 Q63429 Q9QX78	Abce1 Cish3 ENSRNOG00000065554 If1ai1 If1ai2 If1ai3 Ifna1 Ifna12l Ifna4 Ifna4l1 Ifnar1 Ifnar2 Ifnb Ifnb1 Irf9 Jak1 Kpna1 Kpnb1 LOC100360645 LOC100911527 LOC120103158 LOC120103159 LOC120103160 LOC120103161 LOC120103162 LOC120103163 LOC120103164 RGD1560539 Rnasel Rps27a Socs1 Socs3 Stat1 Stat2 Stat4 Tyk2 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
Activation of the AP-1 family of transcription factors	Cyclic AMP-dependent transcription factor ATF-2 Mapk11 protein Mitogen-activated protein kinase 10 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 8 Mitogen-activated protein kinase 9 Protein c-Fos Transcription factor Jun	D4A3U7 P12841 P17325 P21708 P49185 P49186 P49187 P63086 P70618 Q00969	Atf2 Csbp1 Csbp2 Erk1 Erk2 Fos Jnk1 Jnk2 Jnk3 Jun Mapk Mapk1 Mapk10 Mapk11 Mapk14 Mapk3 Mapk8 Mapk9 Prkm1 Prkm10 Prkm3 Prkm8 Prkm9 Rjg-9	Rattus norvegicus (Norway rat)
Cargo concentration in the ER	Alpha-1-antiproteinase Amphiregulin CD59 glycoprotein Cathepsin Z Coagulation factor VIII Collagen type VII alpha 1 chain Cornichon family AMPA receptor auxiliary protein 1 Dipeptidyl peptidase 1 Folate receptor alpha Glutamate receptor 1 Golgi SNAP receptor complex member 2 Guanine nucleotide-exchange factor SEC12 Lectin, mannose-binding 2 MIA SH3 domain ER export factor 2 MIA SH3 domain ER export factor 3 Multiple coagulation factor deficiency protein 2 homolog Protein ERGIC-53-like Protein ERGIC-53 Protein cornichon homolog 2 Protein cornichon homolog 3 Protein transport protein SEC23 Protransforming growth factor alpha SEC24 homolog A, COPII coat complex component SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component Small COPII coat GTPase SAR1B Syntaxin-5 Transmembrane emp24 domain-containing protein 10 Transmembrane emp24 domain-containing protein 2 Vesicle-trafficking protein SEC22b	A0A0G2JVM2 A0A0G2K112 A0A0G2K626 A0A8I5ZSK4 B5DFC3 D0Q0Y7 D3ZE04 D3ZEB1 D3ZW15 D3ZZA8 F7FPK8 G3V8M6 G3V9S9 O35165 P01134 P17475 P19490 P24338 P27274 P80067 Q08851 Q4KM74 Q5BJU5 Q5FB95 Q5HZY2 Q62902 Q63524 Q63584 Q8K5B3 Q9R1T3 Q9WTV0	Areg Cd59 Cnih1 Cnih2 Cnih3 Col7a1 Ctsc Ctsy Ctsz Ergic53 Ergl F8 Folr1 GluA1 Glur1 Gosr2 Gria1 Gs27 Lman1 Lman1l Lman2 Mcfd2 Mia2 Mia3 Preb Rnp24 Sar1b Sdgf Sdnsf Sec12 Sec22b Sec22l1 Sec23a Sec24a Sec24b Sec24c Sec24d Serpina1 Stx5 Stx5a Tgfa Tmed10 Tmed2 Tmp21	Rattus norvegicus (Norway rat)
Elastic fibre formation	Elastin Fibrillin 1 Fibulin-5 Furin Integrin beta-1 Integrin beta-3 Integrin beta-6 Integrin subunit alpha 5 Integrin subunit alpha V Lysyl oxidase homolog 2 Lysyl oxidase homolog Microfibril associated protein 2 Microfibril associated protein 5 Protein-lysine 6-oxidase protein-lysine 6-oxidase protein-lysine 6-oxidase	A0A0G2K1E2 A0A0G2K9S8 B5DF27 D3Z952 D3ZP82 D4A9V5 F1LZX9 G3V9M6 P16636 P23377 P49134 Q5FWS5 Q6AYF4 Q8R2H2 Q99372 Q9WVH8	Dance Eln Fbln5 Fbn1 Fur Furin Itga5 Itgav Itgb1 Itgb3 Itgb6 Lox Loxl1 Loxl2 Loxl3 Loxl4 Mfap2 Mfap5 Pcsk3	Rattus norvegicus (Norway rat)
Disinhibition of SNARE formation	Protein kinase C alpha type Protein kinase C beta type Protein kinase C gamma type Syntaxin binding protein 3 Syntaxin-4	P05696 P63319 P68403 Q08850 Q99PV2	Pkca Pkcb Pkcc Pkcg Prkca Prkcb Prkcb1 Prkcc Prkcg Stx4 Stx4a Stxbp3 munc-18c	Rattus norvegicus (Norway rat)
Pyroptosis	Apoptosis regulator BAX BCL2-antagonist/killer 1 Caspase-1 Caspase-3 Charged multivesicular body protein 2B Charged multivesicular body protein 2a Charged multivesicular body protein 3 Charged multivesicular body protein 4B Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Cytochrome c domain-containing protein Cytochrome c, somatic Elastase, neutrophil expressed Gasdermin D Gasdermin E Granzyme B High mobility group protein B1 High mobility group protein B1 High mobility group protein B1 High mobility group protein B1 Interleukin-1 alpha Interleukin-1 beta Interleukin-18 Similar to Cytochrome c, somatic	A0A096MJ11 A0A0G2K6P4 A0A8I5Y7D7 A0A8I5ZP83 A0A8I5ZY10 A0A8I6AB52 A0A8I6AQ75 A0A8I6GBU6 D3ZXV2 D4A488 D4A5L9 D4A7H9 F1MAG0 F7EQF3 P16598 P18291 P43527 P55213 P62898 P63159 P97636 Q569C1 Q63264 Q63690 Q8CGS4	AC128290.1 Bak1 Bax Casp1 Casp3 Chmp2a Chmp2b Chmp3 Chmp4b Chmp4c Chmp6 Chmp7 Cpp32 Cycs Cycsl2 Cycsl3 Elane Gsdmd Gsdme Gzmb Hmg-1 Hmg1 Hmgb1 Hmgb1-ps33 Hmgb1-ps4 Hmgb1l1 Hmgb1l2 Hmgb1l3 Hmgb1l5 Igif Il18 Il1a Il1b Il1bc Il1bce LOC108349189 LOC108350839 LOC690675 RGD1562558 Vps24	Rattus norvegicus (Norway rat)
PI-3K cascade:FGFR4	Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2-associated binding protein 1 Growth factor receptor-bound protein 2 Klotho beta Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Tyrosine-protein phosphatase non-receptor type 11	A0A0G2K344 A0A8I6B5D5 D3Z8T6 D3ZAL7 D4A244 F1LSQ8 O54769 O88182 P13109 P36364 P41499 P61149 P62994 P63076 Q498D6 Q63787 Q8R5L5 Q8VI81 Q8VI82 Q9EST9	Ash FGF15 FGF6 Fgf-1 Fgf-2 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf19 Fgf2 Fgf20 Fgf23 Fgf4 Fgf6 Fgf7a Fgf7b Fgf8 Fgf8a Fgf9 Fgfa Fgfr4 Frs2 Gab1 Grb2 Klb Pik3ca Pik3r1 Ptpn11	Rattus norvegicus (Norway rat)
Beta oxidation of palmitoyl-CoA to myristoyl-CoA	Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	P45953 Q60587 Q64428	Acadvl Hadha Hadhb	Rattus norvegicus (Norway rat)
Glutamate Neurotransmitter Release Cycle	Amino acid transporter Complexin-1 Excitatory amino acid transporter 1 Excitatory amino acid transporter 2 Excitatory amino acid transporter 3 Excitatory amino acid transporter 4 Glutaminase kidney isoform, mitochondrial Glutaminase liver isoform, mitochondrial Liprin-alpha-3 Liprin-alpha-4 (Fragment) PRA1 family protein 3 PTPRF interacting protein alpha 1 PTPRF interacting protein alpha 2 Peripheral-type benzodiazepine receptor-associated protein 1 Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Sodium-coupled neutral amino acid symporter 2 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Syntaxin-binding protein 1 Vesicle-associated membrane protein 2 Vesicular glutamate transporter 1	A0A1B0GWS0 A0A8I6AK94 D3ZT83 O35921 P13264 P21707 P24942 P28492 P31596 P32851 P51907 P60881 P61765 P63012 P63041 P63045 Q62634 Q62769 Q91Z79 Q91Z80 Q9ES40 Q9JHE5 Q9JIR0 Q9JIR4	Arl6ip5 Ata2 Bnpi Bzrap1 Cplx1 Eaac1 Eaat1 Eaat2 Eaat3 Eaat4 Ga Gls Gls2 Glt1 Gtrap3-18 Jwa Ppfia1 Ppfia2 Ppfia3 Ppfia4 Pra2 Praf3 Rab3a Rbp1 Rim1 Rims1 Sa1 Sap Sat2 Slc17a7 Slc1a1 Slc1a2 Slc1a3 Slc1a6 Slc1a7 Slc38a2 Snap Snap25 Snat2 Stx1a Stxbp1 Syb2 Syt1 Tspoap1 Unc13b Unc13h2 Unc18a Vamp2 Vglut1	Rattus norvegicus (Norway rat)

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