GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **526 - 550** of **1070** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	ATPase family, AAA domain containing 2 Estrogen receptor Glycoprotein hormones alpha chain Lutropin subunit beta	A0A8I5ZNS1 P01230 P06211 P11962	Atad2 Cga Cga1 Esr Esr1 Estr Lhb Nr3a1	Rattus norvegicus (Norway rat)
Endosomal Sorting Complex Required For Transport (ESCRT)	Charged multivesicular body protein 2B Charged multivesicular body protein 2a Charged multivesicular body protein 3 Charged multivesicular body protein 4B Charged multivesicular body protein 4c Charged multivesicular body protein 5 Charged multivesicular body protein 6 Charged multivesicular body protein 7 Hepatocyte growth factor-regulated tyrosine kinase substrate Multivesicular body subunit 12A Multivesicular body subunit 12B Polyubiquitin-B Polyubiquitin-C Signal transducing adapter molecule 2 Signal transducing adaptor molecule Tumor susceptibility gene 101 protein Ubiquitin B-like Ubiquitin-associated protein 1 Ubiquitin-ribosomal protein eS31 fusion protein VPS37B subunit of ESCRT-I VPS37C subunit of ESCRT-I VPS37D subunit of ESCRT-I Vacuolar protein sorting-associated protein 28 homolog Vacuolar protein sorting-associated protein 4A Vacuolar protein-sorting-associated protein 25 Vacuolar protein-sorting-associated protein 36 Vacuolar-sorting protein SNF8 Vesicle trafficking 1 vesicle-fusing ATPase	A0A8I5ZP83 A0A8I5ZY10 A0A8I6A5Y0 A0A8I6A5Y3 A0A8I6AB52 A0A8I6ABB8 A0A8I6ACY9 A0A8I6AQ75 A0A8I6GH80 B2GV76 B5DEN9 B5DF55 B5DFF4 D4A7H9 P0C0A1 P0C0A2 P0CG51 P62982 Q4QQV8 Q569C1 Q5RK19 Q5XHY7 Q5XIS7 Q63429 Q6IRE4 Q6P777 Q793F9 Q8CGS4 Q9JJ50	Chmp2a Chmp2b Chmp3 Chmp4b Chmp4c Chmp5 Chmp6 Chmp7 Eap20 Eap30 Eap45 Fam125a Hgs Hrs Hrs2 LOC100360645 Mvb12a Mvb12b NEWGENE_1309258 Rps27a Snf8 Stam Stam2 Tsg101 Uba80 Ubap1 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Vps24 Vps25 Vps28 Vps36 Vps37b Vps37c Vps37d Vps4a Vps4b Vta1 vps4-A	Rattus norvegicus (Norway rat)
Sealing of the nuclear envelope (NE) by ESCRT-III	Charged multivesicular body protein 2B Charged multivesicular body protein 2a Charged multivesicular body protein 3 Charged multivesicular body protein 4B Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Coiled-coil and C2 domain-containing protein 1B IST1 homolog Spastin Tubulin alpha chain Tubulin alpha-1A chain Tubulin alpha-1B chain Tubulin alpha-1C chain Tubulin alpha-3 chain Tubulin alpha-4A chain Tubulin alpha-8 chain Tubulin beta chain Tubulin beta-2A chain Tubulin beta-2B chain Tubulin beta-3 chain Tubulin beta-4B chain Vacuolar protein sorting-associated protein 4A	A0A8I5ZP83 A0A8I5ZY10 A0A8I6AB52 A0A8I6AQ75 B2RYN7 D4A7H9 F1LUM5 M0R8B6 P68370 P85108 Q3KRE8 Q4QRB4 Q568Z6 Q569C1 Q5FVK6 Q5XIF6 Q68FR8 Q6AY56 Q6AYZ1 Q6P9T8 Q6P9V9 Q793F9 Q8CGS4	Cc2d1b Chmp2a Chmp2b Chmp3 Chmp4b Chmp4c Chmp6 Chmp7 Ist1 LOC679312 Spast Spg4 Tuba1 Tuba1a Tuba1b Tuba1c Tuba2 Tuba3 Tuba3a Tuba3b Tuba4 Tuba4a Tuba6 Tuba8 Tubal3 Tubb1 Tubb2a Tubb2b Tubb2c Tubb3 Tubb4b Vps24 Vps4a vps4-A	Rattus norvegicus (Norway rat)
Azathioprine ADME	ATP-binding cassette sub-family C member 5 ATP-binding cassette subfamily C member 4 Equilibrative nucleoside transporter 1 Equilibrative nucleoside transporter 2 GMP synthase [glutamine-hydrolyzing] Glutathione S-transferase A6 Glutathione S-transferase Mu 2 Glutathione S-transferase alpha-1 Glutathione S-transferase alpha-2 Glutathione S-transferase alpha-3 Glutathione S-transferase alpha-5 Hypoxanthine-guanine phosphoribosyltransferase Inosine-5'-monophosphate dehydrogenase 1 Inosine-5'-monophosphate dehydrogenase 2 Nucleoside diphosphate kinase A Nucleoside diphosphate kinase B Nudix hydrolase 15 Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Sodium/nucleoside cotransporter 2 Solute carrier family 28 member 3 Thiopurine S-methyltransferase Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 Xanthine dehydrogenase/oxidase guanylate kinase	A0A8I5ZPB5 A0A8I6A2B3 D3ZKQ0 D3ZLZ7 D3ZYG0 E9PU28 F1M3J4 O54698 O54699 P00502 P04903 P04904 P08010 P19804 P22985 P27605 P46418 P54100 Q05982 Q4V7C6 Q62773 Q6AXY0 Q6RUV5 Q8VIH3 Q9QYM0 Q9Z0T0	Abcc4 Abcc5 Cnt2 Cnt3 Ent1 Ent2 Gmps Gsta1 Gsta2 Gsta3 Gsta5 Gsta6 Gstm2 Gstyc1 Gstyc2 Guk1 Hprt Hprt1 Impdh1 Impdh2 Mrp4 Mrp5 Nme1 Nme2 Nudt15 Rac Rac1 Slc28a2 Slc28a3 Slc29a1 Slc29a2 Spnt Tpmt Vav Vav1 Vav2 Vav3 Xdh	Rattus norvegicus (Norway rat)
EPH-ephrin mediated repulsion of cells	72 kDa type IV collagenase Ephrin B3 Ephrin type-B receptor 1 Ephrin type-B receptor 3 Ephrin type-B receptor 6 Ephrin-B1 Gamma-secretase subunit APH-1 Gamma-secretase subunit PEN-2 Matrix metalloproteinase-9 Nicastrin Presenilin-1 Presenilin-2 Proto-oncogene tyrosine-protein kinase Src Ras-related C3 botulinum toxin substrate 1 TIAM Rac1 associated GEF 1 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 receptor protein-tyrosine kinase receptor protein-tyrosine kinase	A0A8I5ZPB5 A0A8I6AC12 D3ZH39 D3ZYG0 F1LM93 F1MAJ0 F7EYZ3 G3V7D4 M0RDA4 O88777 P09759 P0C0K7 P33436 P50282 P52796 P97887 Q07014 Q62844 Q6QI68 Q6RUV5 Q8CGU6 Q9WUD9	Aph1a Efnb1 Efnb3 Elk Ephb1 Ephb2 Ephb3 Ephb4 Ephb6 Eplg2 Epth2 Fyn LOC686310 Lerk2 Lyn Mmp2 Mmp9 Ncstn Ps2 Psen1 Psen2 Psenen Psnl1 Psnl2 Rac Rac1 Src Tiam1 Vav2 Vav3 Yes1	Rattus norvegicus (Norway rat)
Aggrephagy	ADP-ribosylation factor like GTPase 13B Centrin 1 Cystic fibrosis transmembrane conductance regulator Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic E3 ubiquitin-protein ligase parkin Intraflagellar transport 88 Parkinson disease protein 7 homolog Pericentrin Polyubiquitin-B Polyubiquitin-C Ubiquitin B-like Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eS31 fusion protein	A0A8I5ZPQ6 A0A8I6A3Q1 A0A8I6A5Y3 D3ZMY8 G3V832 M0RDU9 O88767 P0CG51 P34158 P38650 P62982 P63170 Q62698 Q62871 Q63100 Q63429 Q78P75 Q9JK66 Q9QXU8	Abcc7 Arl13b Cap1 Cetn1 Cftr Dhc1 Dlc2 Dnch1 Dnchc1 Dnci1 Dnci2 Dncic1 Dncic2 Dncl1 Dnclc1 Dncli1 Dncli2 Dnec1 Dyhc Dync1h1 Dync1i1 Dync1i2 Dync1li1 Dync1li2 Dynll1 Dynll2 ENSRNOG00000067007 Ift88 LOC100360645 LOC309692 Map1c Park2 Park7 Pcnt Pin Prkn Rps27a Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
RHOU GTPase cycle	ARF GTPase-activating protein GIT1 ARF GTPase-activating protein GIT2 Cell division control protein 42 homolog Clathrin heavy chain 1 Cytoplasmic protein Cytoplasmic protein DEP domain containing 1B Discs large MAGUK scaffold protein 5 Dystonin E3 ubiquitin-protein ligase Growth factor receptor-bound protein 2 Hepatocyte growth factor-regulated tyrosine kinase substrate IQ motif containing GTPase activating protein 1 Intersectin 2 Partitioning defective 6 homolog alpha Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Protein-tyrosine kinase 2-beta Pseudopodium-enriched atypical kinase 1 Ras homolog family member U Rho GTPase activating protein 30 Rho GTPase activating protein 31 Rho guanine nucleotide exchange factor 6 Rho guanine nucleotide exchange factor 7 SLIT-ROBO Rho GTPase-activating protein 2 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Signal transducing adapter molecule 2 Signal transducing adaptor molecule Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain Thioredoxin-like protein 1 Unconventional myosin-VI Vang-like protein non-specific serine/threonine protein kinase receptor protein-tyrosine kinase tRNA (34-2'-O)-methyltransferase regulator WDR6	A0A8I5ZQD4 A0A8I6A8K6 A0A8I6ACM8 A0A8I6AMY1 A0A8I6GLX4 B2RZ33 B4F767 B5DF55 B5DF62 D3ZBN3 D3ZCI3 D3ZKC8 D4A208 D4A3M8 D4A563 D4A987 D4AA32 G3V6S0 G3V7Q7 O55043 P11442 P16086 P35465 P62994 P70600 Q5XFW6 Q5XHY7 Q5XXR3 Q62829 Q63787 Q63788 Q64303 Q66H91 Q6B4M5 Q8CFN2 Q920J4 Q9JJ50 Q9Z272	Arhgap30 Arhgap31 Arhgef6 Arhgef7 Ash Cdc42 Cltc Depdc1b Dlg5 Dst Epha2 Fak2 Git1 Git2 Grb2 Hgs Hrs Hrs2 Iqgap1 Itsn2 Myo6 Nck1 Nck2 Pak1 Pak2 Pak3 Pak3bp Pak4 Par-6a Par6a Pard6a Peak1 Pik3r1 Pik3r2 Pixb Ptk2b Pyk2 RGD1312026 Rhou Spna2 Spta2 Sptan1 Sptbn1 Srgap2 Stam Stam2 Trp Txnl1 Vangl1 Wdr6 Wwp2	Rattus norvegicus (Norway rat)
RHOV GTPase cycle	ARF GTPase-activating protein GIT1 ARF GTPase-activating protein GIT2 Cell division control protein 42 homolog Centriolar coiled-coil protein 110 Centrosomal protein 97 Clathrin heavy chain 1 Cytoplasmic protein Cytoplasmic protein DEP domain containing 1B Discs large MAGUK scaffold protein 5 Dystonin E3 ubiquitin-protein ligase SH3RF1 IQ motif containing GTPase activating protein 1 Mitogen-activated protein kinase kinase kinase 11 Par-6 family cell polarity regulator beta Partitioning defective 6 homolog alpha Phosphatidylinositol 3-kinase regulatory subunit alpha Pseudopodium-enriched atypical kinase 1 Rho GTPase activating protein 12 Rho guanine nucleotide exchange factor 7 Rho-related GTP-binding protein RhoV Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain Thioredoxin-like protein 1 Tropomyosin alpha-4 chain Unconventional myosin-IXa Vang-like protein Zinc finger protein 512B non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase receptor protein-tyrosine kinase tRNA (34-2'-O)-methyltransferase regulator WDR6	A0A8I5ZQD4 A0A8I6AJD9 A0A8I6AN18 A0A8I6GLX4 B2RZ33 B5DF62 D3ZBN3 D3ZKC8 D3ZQ51 D4A2F2 D4A3J9 D4A3M8 D4A563 D4AA32 D4AC95 G3V6S0 G3V7Q7 O55043 P09495 P11442 P16086 P35465 Q5XFW6 Q63787 Q64303 Q66H91 Q66HA1 Q6B4M5 Q71F54 Q8CFN2 Q920J4 Q9Z1N3 Q9Z1Y0 Q9Z272	Arhgap12 Arhgef7 Ccp110 Cdc42 Cep97 Cltc Depdc1b Dlg5 Dst Epha2 Git1 Git2 Iqgap1 Map3k11 Mlk3 Myo9a Myr7 Nck1 Nck2 Pak1 Pak2 Pak3bp Pak4 Pak6 Par-6a Par6a Pard6a Pard6b Peak1 Pik3r1 Pixb Posh Posh1 RGD1312026 Rhov Sh3md2 Sh3rf1 Spna2 Spta2 Sptan1 Sptbn1 Tpm4 Trp Txnl1 Vangl1 Wdr6 Zfp512b	Rattus norvegicus (Norway rat)
Type I hemidesmosome assembly	CD151 antigen Collagen type XVII alpha 1 chain Dystonin Integrin beta-4 Integrin subunit alpha 6 Multiple epidermal growth factor-like domains protein 6 Plectin	A0A8I5ZQD4 A0A8I6AJE9 A0A8I6GBI7 O88281 P30427 Q64632 Q9QZA6	Cd151 Col17a1 Dst Egfl3 Itga6 Itgb4 Megf6 Peta3 Plec Plec1	Rattus norvegicus (Norway rat)
Branched-chain amino acid catabolism	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (Fragment) 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial 3-hydroxyacyl-CoA dehydrogenase type-2 3-hydroxyisobutyrate dehydrogenase, mitochondrial 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial Acetyl-CoA acetyltransferase, mitochondrial Acyl-CoA dehydrogenase family, member 8 Branched-chain alpha-ketoacid dehydrogenase kinase Branched-chain-amino-acid aminotransferase, cytosolic Branched-chain-amino-acid aminotransferase, mitochondrial Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex Dihydrolipoyl dehydrogenase, mitochondrial Enoyl-CoA hydratase, mitochondrial Isovaleryl-CoA dehydrogenase, mitochondrial Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial Methylglutaconyl-CoA hydratase, mitochondrial Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial	A0A8I5ZQL5 B2GV15 F1LU71 O35854 O70351 P11960 P12007 P14604 P17764 P29266 P35738 P54690 P70584 Q00972 Q02253 Q5I0C3 Q5XIE6 Q5XIT9 Q6P6R2	Acad8 Acadsb Acat1 Aldh6a1 Auh Bcat1 Bcat2 Bcatm Bckdha Bckdhb Bckdk Dbt Dld Eca40 Echs1 Erab Hadh2 Hibadh Hibch Hsd17b10 Ivd Mcca Mccc1 Mccc2 Mmsdh	Rattus norvegicus (Norway rat)
Caspase-mediated cleavage of cytoskeletal proteins	Alpha-adducin Caspase 7 Caspase-3 Caspase-6 Caspase-8 Gelsolin Growth arrest-specific 2 Microtubule-associated protein tau Plectin Sorbin and SH3 domain-containing protein 2 Spectrin alpha chain, non-erythrocytic 1 Vimentin	A0A8I5ZQU7 G3V857 O35397 O35413 P16086 P19332 P30427 P31000 P55213 Q63028 Q68FP1 Q9JHX4	Add1 Argbp2 Casp3 Casp6 Casp7 Casp8 Cpp32 Gas2 Gsn Mapt Mch2 Mtapt Plec Plec1 Sorbs2 Spna2 Spta2 Sptan1 Tau Vim	Rattus norvegicus (Norway rat)
Nephrin family interactions	Cytoplasmic protein Cytoplasmic protein IQ motif containing GTPase activating protein 1 Kin of IRRE-like protein 1 Kirre like nephrin family adhesion molecule 2 Kirre like nephrin family adhesion molecule 3 Nephrin Tyrosine-protein kinase Fyn	A0A8I5ZQV3 B2RZ33 D4A3M8 D4A934 G3V7Q7 Q62844 Q6X936 Q9R044	Fyn Iqgap1 Kirrel Kirrel1 Kirrel2 Kirrel3 Nck1 Nck2 Neph1 Nphn Nphs1	Rattus norvegicus (Norway rat)
MAP2K and MAPK activation	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Beta-arrestin-1 Beta-arrestin-2 Connector enhancer of kinase suppressor of Ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase KRas GTPase NRas IQ motif containing GTPase activating protein 1 Integrin beta-3 Integrin subunit alpha 2b Interleukin 17 receptor D Kinase suppressor of ras 1 Kinase suppressor of ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Phosphatidylethanolamine-binding protein 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ragulator complex protein LAMTOR3 Ras-related protein Rap-1A Ras-related protein Rap-1b Roadblock/LAMTOR2 domain-containing protein Serine/threonine-protein kinase A-Raf Talin 1 Tyrosine-protein kinase CSK Vinculin WD repeat domain-containing protein 83 non-specific serine/threonine protein kinase	A0A8I5ZQW6 A0A8I6ABG6 A0A8I6ADH7 A0A8I6AI85 A0A8I6ATH0 A0A8I6GGN2 D3ZDZ1 D3ZGQ0 F1LY04 G3V7Q7 P02680 P04937 P06399 P08644 P11345 P14056 P14480 P20171 P21708 P29066 P29067 P31044 P32577 P35213 P36506 P62836 P63086 P85972 Q01986 Q04970 Q5BLX8 Q5U204 Q62636 Q8R2H2 Q8VHF0 Q9WUD9 Q9Z1T4	A-raf Apbb1ip Araf Araf1 Arrb1 Arrb2 Braf Cnksr1 Cnksr2 Csk ENSRNOG00000066475 Erk1 Erk2 Fga Fgb Fgg Fn1 Hras Hras1 Il17rd Iqgap1 Itga2b Itgb3 Kras Kras2 Krev1 Ksr1 Ksr2 Lamtor3 Map2k1 Map2k1ip1 Map2k2 Mapk Mapk1 Mapk3 Mark3 Mek1 Mek2 Mkk2 Morg1 Nras Pbp Pebp Pebp1 Prkm1 Prkm3 Prkmk1 Prkmk2 RGD1562674 Raf Raf1 Rap1a Rap1b Src Tln1 Vcl Wdr83 Ywhab	Rattus norvegicus (Norway rat)
RHOH GTPase cycle	Caveolin-1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex Fam91a1 protein Glioblastoma amplified sequence Junction plakoglobin Methionine synthase NSFL1 cofactor p47 Neutral amino acid transporter B(0) Proto-oncogene tyrosine-protein kinase LCK Ragulator complex protein LAMTOR1 Ral GTPase-activating protein subunit alpha-1 Ras homolog family member H Ras-related protein Rab-7a Rho GDP dissociation inhibitor beta Rho GDP dissociation inhibitor gamma Rho GDP-dissociation inhibitor 1 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 5 Sodium bicarbonate cotransporter 3 Stomatin Transferrin receptor protein 1 Transitional endoplasmic reticulum ATPase Transmembrane protein 59 Tubulin alpha-1B chain Tyrosine-protein kinase CSK Tyrosine-protein kinase Uveal autoantigen with coiled-coil domains and ankyrin repeats Vang-like protein Vesicle-associated membrane protein 3 WD repeat domain 11 non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A8I5ZRJ5 A0A8I5ZV26 A0A8I5ZXI2 A0A8I6AHV6 B2GV15 B2RYP3 B5DF62 D3Z9L5 D3ZGS5 D3ZJ25 D3ZKC8 D3ZQ51 D3ZTP3 D4A280 O35987 O55007 P09527 P32577 P35465 P41350 P46462 P63025 Q01621 Q5BJZ5 Q5RK08 Q5XI73 Q62868 Q63644 Q64303 Q6P0K8 Q6P791 Q6P9V9 Q99376 Q9R1N3 Q9Z2Q4	Arhgdia Arhgdib Arhgdig Cav Cav1 Csk Dbt Fam91a1 Garnl1 Gbas Jup LOC498174 Lamtor1 Lck Mtr Nbc Nbc2 Nbc3 Nbcn1 Nipsnap2 Nsfl1c Pak1 Pak2 Pak4 Pak5 Pak6 Pak7 Pg RGD1310313 Rab7 Rab7a Ralgapa1 Rhoh Rock1 Rock2 Slc1a5 Slc4a7 Stom Syb3 Tfrc Tmem59 Trfr Tuba1b Tuba2 Tulip1 Uaca Vamp3 Vangl1 Vcp Wdr11 Zap70	Rattus norvegicus (Norway rat)
Protein lipoylation	Acyl carrier protein Adrenodoxin, mitochondrial Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial Glycine cleavage system H protein, mitochondrial Lipoyl synthase, mitochondrial Lipoyltransferase 1 NFU1 iron-sulfur cluster scaffold homolog, mitochondrial Octanoyl-[acyl-carrier-protein]	A0A8I5ZRJ8 B2GV15 D3Z9Z2 D3ZA85 D3ZF13 P08461 P24483 Q01205 Q5I0P2 Q5XIH4	Dbt Dlat Dlst Fdx1 Gcsh Lias Lipt1 Lipt2 Ndufab1 Nfu1	Rattus norvegicus (Norway rat)
mTORC1-mediated signalling	14-3-3 protein beta/alpha AKT1 substrate 1 Eukaryotic elongation factor 2 kinase Eukaryotic translation initiation factor 4 gamma 1 Eukaryotic translation initiation factor 4E-binding protein 1 Eukaryotic translation initiation factor 4E GTP-binding protein Rheb Neutral amino acid transporter 9 Peptidyl-prolyl cis-trans isomerase FKBP1A Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein Ras-related GTP-binding protein Regulatory associated protein of MTOR, complex 1 Ribosomal protein S6 kinase beta-1 Roadblock/LAMTOR2 domain-containing protein Serine/threonine-protein kinase mTOR Small ribosomal subunit protein eS6 Target of rapamycin complex subunit LST8	A0A8I5ZRQ9 A0A8I6ADH7 B2RZ38 D3ZDU2 D3ZF11 D4AD29 M0RD03 P35213 P42346 P62755 P63074 P67999 P70531 Q0D2L6 Q3B8Q3 Q5U204 Q62622 Q62639 Q62658 Q63486 Q63487 Q6P791 Q9Z2K5	Akt1s1 ENSRNOG00000066475 Eef2k Eif4e Eif4ebp1 Eif4g1 Fkbp1 Fkbp1a Frap1 Gbl Lamtor1 Lamtor3 Lamtor4 Lamtor5 Lst8 Map2k1ip1 Mlst8 Mtor Raft1 Rheb Rps6 Rps6kb1 Rptor RragB Rraga Rragc Rragc_predicted Rragd Slc38a9 Ywhab	Rattus norvegicus (Norway rat)
MTOR signalling	14-3-3 protein beta/alpha AKT1 substrate 1 GTP-binding protein Rheb Neutral amino acid transporter 9 RAC-alpha serine/threonine-protein kinase Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein Ras-related GTP-binding protein Regulatory associated protein of MTOR, complex 1 Roadblock/LAMTOR2 domain-containing protein Serine/threonine-protein kinase mTOR Target of rapamycin complex subunit LST8	A0A8I5ZRQ9 A0A8I6ADH7 B2RZ38 D3ZDU2 D3ZF11 D4AD29 P35213 P42346 P47196 Q0D2L6 Q3B8Q3 Q5U204 Q62639 Q63486 Q63487 Q6P791 Q9Z2K5	Akt1 Akt1s1 ENSRNOG00000066475 Frap1 Gbl Lamtor1 Lamtor3 Lamtor4 Lamtor5 Lst8 Map2k1ip1 Mlst8 Mtor Raft1 Rheb Rptor RragB Rraga Rragc Rragc_predicted Rragd Slc38a9 Ywhab	Rattus norvegicus (Norway rat)
HSF1-dependent transactivation	AKT1 substrate 1 Alpha-crystallin B chain Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma DnaJ heat shock protein family (Hsp40) member B1 Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock factor-binding protein 1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heat shock protein beta-8 Heat shock transcription factor 1 Regulatory associated protein of MTOR, complex 1 Serine/threonine-protein kinase mTOR Target of rapamycin complex subunit LST8	A0A8I5ZRQ9 D3ZDU2 D3ZUU5 F1MAF1 P08413 P0DMW0 P0DMW1 P11275 P11730 P15791 P23928 P34058 P42346 P55063 P63018 P82995 Q8K3X8 Q9EPX0 Q9Z2K5	Akt1s1 Camk2a Camk2b Camk2d Camk2g Cryab Cryac Dnajb1 Frap1 Gbl Hsbp1 Hsc70 Hsc73 Hsf1 Hsp22 Hsp70-1 Hsp70-2 Hsp70-3 Hsp84 Hsp86 Hsp90aa1 Hsp90ab1 Hspa1 Hspa1a Hspa1b Hspa1l Hspa2 Hspa8 Hspb8 Hspc3 Hspca Hspcb Lst8 Mlst8 Mtor Raft1 Rptor	Rattus norvegicus (Norway rat)
Relaxin receptors	Insulin-like 3 Prorelaxin 1 Relaxin family peptide receptor 2 Relaxin receptor 1 Relaxin-3	A0A8I5ZRR3 P01347 Q6R6I6 Q8BFS3 Q9WUK0	Insl3 Insl7 Lgr7 Rlf Rln Rln1 Rln3 Rxfp1 Rxfp2	Rattus norvegicus (Norway rat)
Beta-oxidation of pristanoyl-CoA	Acyl-coenzyme A oxidase Acyl-coenzyme A thioesterase 8 Alpha-methylacyl-CoA racemase Carnitine O-acetyltransferase Peroxisomal acyl-coenzyme A oxidase 2 Peroxisomal acyl-coenzyme A oxidase 3 Peroxisomal carnitine O-octanoyltransferase Peroxisomal multifunctional enzyme type 2 Sterol carrier protein 2	A0A8I5ZRR5 P11466 P11915 P70473 P97562 P97852 Q63448 Q704S8 Q8VHK0	Acot8 Acox2 Acox3 Acoxl Amacr Cot Crat Crot Edh17b4 Hsd17b4 Prcox Pte1 Scp-2 Scp2 Thcox	Rattus norvegicus (Norway rat)
Oncogene Induced Senescence	Cellular tumor antigen p53 Cyclin dependent kinase inhibitor 2D Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 DNA-binding protein inhibitor ID-1 E3 ubiquitin-protein ligase Mdm2 ETS proto-oncogene 2, transcription factor Ets2 repressor factor Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Protein C-ets-1 Protein Mdm4 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A8I5ZS11 A0A8I6A5Y3 A0A8I6A9F0 A0A8I6G5V3 F1MA87 P0CG51 P10361 P21708 P35426 P41135 P41156 P55272 P62982 P63086 Q5XIN1 Q63429 Q6P4Z7	Cdk4 Cdk6 Cdkn2b Cdkn2d Erf Erk1 Erk2 Ets-1 Ets1 Ets2 Id-1 Id1 Ink4 LOC100360645 Mapk Mapk1 Mapk3 Mdm2 Mdm4 Mdmx P53 Prkm1 Prkm3 Rps27a Tp53 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
Acrosome Reaction and Sperm:Oocyte Membrane Binding	Acrosin CD9 antigen IZUMO family member 2 IZUMO family member 3 IZUMO family member 4 Izumo sperm-egg fusion protein 1	A0A8I5ZSN1 D3ZRD5 M0R6I5 P29293 P40241 Q6AY06	Acr Cd9 Izumo1 Izumo2 Izumo3 Izumo4	Rattus norvegicus (Norway rat)
RHO GTPases regulate CFTR trafficking	Cystic fibrosis transmembrane conductance regulator Golgi associated PDZ and coiled-coil motif containing Rho-related GTP-binding protein RhoQ	A0A8I5ZTW6 P34158 Q9JJL4	Abcc7 Cftr Gopc Rhoq Tc10	Rattus norvegicus (Norway rat)
G alpha (s) signalling events	3',5'-cyclic-AMP phosphodiesterase 4A 3',5'-cyclic-AMP phosphodiesterase 4C (Fragment) 3',5'-cyclic-AMP phosphodiesterase 4D Beta-2 adrenergic receptor Beta-adrenergic receptor kinase 1 Beta-arrestin-1 Beta-arrestin-2 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B G protein-coupled receptor kinase 3 G protein-coupled receptor kinase 5 G protein-coupled receptor kinase 6 High affinity 3',5'-cyclic-AMP phosphodiesterase 7A (Fragment) Phosphodiesterase Phosphodiesterase Phosphodiesterase Phosphodiesterase cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A cGMP-dependent 3',5'-cyclic phosphodiesterase cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B	A0A8I5ZTX5 A0A8I5ZWQ4 A0A8I6A416 O08593 P10608 P14270 P14644 P26817 P26819 P29066 P29067 P54748 P97711 Q01062 Q01066 Q62833 Q62865 Q63085 Q76KC6 Q8VID6 Q9QYJ6	Adrb2 Adrb2r Adrbk1 Adrbk2 Arrb1 Arrb2 Dpde1 Gprk5 Gprk6 Grk2 Grk3 Grk5 Grk6 Pde10a Pde11a Pde1a Pde1b Pde1b1 Pde2a Pde3a Pde3b Pde4a Pde4c Pde4d Pde7a Pde7b Pde8a Pde8b RNPDE8A	Rattus norvegicus (Norway rat)
RHOBTB2 GTPase cycle	Actin, cytoplasmic 2 Alpha-actinin-1 Cullin-3 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heterogeneous nuclear ribonucleoprotein C Hsp90 co-chaperone Cdc37 Musashi RNA-binding protein 2 Pleckstrin homology domain interacting protein RNA-binding motif protein, X chromosome Rho-related BTB domain containing 2 Serine and arginine repetitive matrix 1 Serine/threonine kinase 38 Spliceosome RNA helicase Ddx39b T-complex protein 1 subunit beta T-complex protein 1 subunit eta T-complex protein 1 subunit zeta Thioredoxin-like protein 1 Transformer-2 protein homolog beta Tropomodulin 3 Twinfilin-1 Unconventional myosin-VI	A0A8I5ZV38 A0A8I6ACM8 A0A8I6AQW7 A0A8I6AR12 B5DF89 F1M3B3 F7ELS2 F7F0R0 G3V9Q4 G3V9R8 P34058 P62997 P63259 P82995 Q4V898 Q5BJV7 Q5RJR2 Q5XIM9 Q63413 Q63692 Q920J4 Q9Z1P2	Actg Actg1 Actn1 Bat1 Bat1a Cct2 Cct6a Cct7 Cctb Cdc37 Cul3 Ddx39b Hnrnpc Hnrpc Hsp84 Hsp86 Hsp90aa1 Hsp90ab1 Hspc3 Hspca Hspcb Msi2 Myo6 Phip Ptk9 Rbmx Rbmxrt Rhobtb2 Sfrs10 Srrm1 Stk38 Tmod3 Tra2b Trp Twf1 Txnl1 Uap56	Rattus norvegicus (Norway rat)

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