nephrotic syndrome

Summary
Definition
A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.
Super Class
nephrosis
Disease Ontology
DOID:1184
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
Related Genes
Displaying entries 41 - 50 of 57 in total
Gene ID Gene Symbol Description Source
7827 NPHS2 NPHS2 stomatin family member, podocin
7941 PLA2G7 phospholipase A2 group VII
8435 SOAT2 sterol O-acyltransferase 2
8694 DGAT1 diacylglycerol O-acyltransferase 1
8879 SGPL1 sphingosine-1-phosphate lyase 1
10891 PPARGC1A PPARG coactivator 1 alpha
23607 CD2AP CD2 associated protein
26130 GAPVD1 GTPase activating protein and VPS9 domains 1
27235 COQ2 coenzyme Q2, polyprenyltransferase
30011 SH3KBP1 SH3 domain containing kinase binding protein 1
Displaying entries 11 - 20 of 40 in total
Gene ID Gene Symbol Description Source
14107 Fat1 FAT atypical cadherin 1
14723 Gp1ba glycoprotein 1b, alpha polypeptide
14775 Gpx1 glutathione peroxidase 1
14815 Nr3c1 nuclear receptor subfamily 3, group C, member 1
15450 Lipc lipase, hepatic
16005 Igfals insulin-like growth factor binding protein, acid labile subunit
16181 Il1rn interleukin 1 receptor antagonist
16189 Il4 interleukin 4
16191 Il5 interleukin 5
18383 Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
Displaying entries 11 - 20 of 23 in total
Gene ID Gene Symbol Description Source
29436 Tfpi tissue factor pathway inhibitor
29527 Ptgs2 prostaglandin-endoperoxide synthase 2
54225 Apob apolipoprotein B
60582 Il1rn interleukin 1 receptor antagonist
64563 Nphs1 NPHS1 adhesion molecule, nephrin
79126 Cfi complement factor I
79438 Igfals insulin-like growth factor binding protein, acid labile subunit
83516 Ppargc1a PPARG coactivator 1 alpha
113936 Cpb2 carboxypeptidase B2
287287 Il4 interleukin 4
Displaying all 10 entries
Gene ID Gene Symbol Description Source
31290 rst roughest
31292 kirre kin of irre
33005 Nep3 Neprilysin 3
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
36546 CtsL1 Cathepsin L1
40191 kug kugelei
45815 Spn27A Serpin 27A
49804 Spn88Ea Serpin 88Ea
49808 Spn42Dd Serpin 42Dd
Displaying all 2 entries
Gene ID Gene Symbol Description Source
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
100004455 epoa erythropoietin a
Displaying 1 entry
Gene ID Gene Symbol Description Source Organism
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
173685 nep-11 Neprilysin-11
174116 gldi-2 EGF-like domain-containing protein
174306 unc-105 Degenerin-like protein unc-105
174787 nep-1 Neprilysin-1
175590 cdh-4 Cadherin-4
177494 unc-8 Degenerin unc-8
178585 srp-1 Serpin domain-containing protein
179195 srp-7 Serpin domain-containing protein
180111 cpl-1 Cathepsin L-like
180555 syg-1 Ig-like domain-containing protein;Synaptogenesis protein syg-1
Displaying all 5 entries
Gene ID Gene Symbol Description Source
851888 DPL1 sphinganine-1-phosphate aldolase DPL1
852546 GPX2 glutathione peroxidase GPX2
853842 GPX1 glutathione peroxidase GPX1
854822 PAN1 Pan1p
856533 ECM14 putative metallocarboxypeptidase

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Acknowledgements

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Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024