neurodegenerative disease

Summary
Synonym
  • degenerative disease
Definition
A central nervous system disease that results in the progressive deterioration of function or structure of neurons.
Super Class
central nervous system disease
Disease Ontology
DOID:1289
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 81 - 90 of 106 in total
Gene ID Gene Symbol Description Source
26524 LATS2 large tumor suppressor kinase 2
29978 UBQLN2 ubiquilin 2
29979 UBQLN1 ubiquilin 1
51087 YBX2 Y-box binding protein 2
51422 PRKAG2 protein kinase AMP-activated non-catalytic subunit gamma 2
53335 BCL11A BCL11 transcription factor A
53632 PRKAG3 protein kinase AMP-activated non-catalytic subunit gamma 3
54893 MTMR10 myotubularin related protein 10
55666 NPLOC4 NPL4 homolog, ubiquitin recognition factor
56893 UBQLN4 ubiquilin 4
Displaying entries 11 - 20 of 73 in total
Gene ID Gene Symbol Description Source
14810 Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1)
15382 Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1
16573 Kif5b kinesin family member 5B
16798 Lats1 large tumor suppressor
17169 Mark3 MAP/microtubule affinity regulating kinase 3
17758 Map4 microtubule-associated protein 4
17762 Mapt microtubule-associated protein tau
18033 Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
18979 Pon1 paraoxonase 1
19167 Psma3 proteasome subunit alpha 3
Displaying entries 1 - 10 of 33 in total
Gene ID Gene Symbol Description Source
24335 Epo erythropoietin
24408 Grin1 glutamate ionotropic receptor NMDA type subunit 1
24767 Scnn1b sodium channel epithelial 1 subunit beta
24768 Scnn1g sodium channel epithelial 1 subunit gamma
24849 Tpi1 triosephosphate isomerase 1
25122 Scnn1a sodium channel epithelial 1 subunit alpha
25550 Slc1a1 solute carrier family 1 member 1
25721 Got2 glutamic-oxaloacetic transaminase 2
29482 Slc1a2 solute carrier family 1 member 2
29483 Slc1a3 solute carrier family 1 member 3
Displaying entries 11 - 15 of 15 in total
Gene ID Gene Symbol Description Source
38742 GluRIA Glutamate receptor IA
38895 Sarm Sterile alpha and Armadillo motif
39836 st scarlet
40665 Nmdar1 NMDA receptor 1
43582 Tpi Triose phosphate isomerase
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
192309 tpi1a triosephosphate isomerase 1a
403143 sarm1 sterile alpha and TIR motif containing 1
406411 rhoaa ras homolog gene family, member Aa
406659 rhoac ras homolog gene family, member Ac
407667 asic4b acid-sensing (proton-gated) ion channel family member 4b
407668 asic4a acid-sensing (proton-gated) ion channel family member 4a
407669 asic2 acid-sensing (proton-gated) ion channel 2
407670 asic1c acid-sensing (proton-gated) ion channel 1c
407672 asic1b acid-sensing (proton-gated) ion channel 1b
436718 rhocb ras homolog family member Cb
Displaying all 3 entries
Gene ID Gene Symbol Description Source Organism
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
100038162 tpi1 triosephosphate isomerase 1 Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
173064 ced-1 Cell death abnormality protein 1
173631 ptc-3 Protein patched homolog 3
174274 ptc-1 Protein patched homolog 1;SSD domain-containing protein
175502 tir-1 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;NAD(+) hydrolase tir-1;Sterile alpha and TIR motif-containing protein 1
176204 glr-1 Glutamate receptor 1
176291 eat-4 Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4
176441 vglu-2 Major facilitator superfamily (MFS) profile domain-containing protein
176442 vglu-3 putative vesicular glutamate transporter vglu-3
177882 glt-3 Putative sodium-dependent excitatory amino acid transporter glt-3
180783 apl-1 Amyloid-beta-like protein
Displaying all 10 entries
Gene ID Gene Symbol Description Source
851013 ACO1 aconitate hydratase ACO1
851620 TPI1 triose-phosphate isomerase TPI1
853173 MTM1 Mtm1p
853770 BUD2 GTPase-activating protein BUD2
853792 OSI1 Osi1p
854943 NTE1 lysophospholipase
855392 FIG4 phosphatidylinositol-3,5-bisphosphate 5-phosphatase
855897 HRR25 serine/threonine protein kinase HRR25
856294 RHO1 Rho family GTPase RHO1
856422 RPN1 proteasome regulatory particle base subunit RPN1

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Last updated: December 9, 2024