neurodegenerative disease

Summary
Synonym
  • degenerative disease
Definition
A central nervous system disease that results in the progressive deterioration of function or structure of neurons.
Super Class
central nervous system disease
Disease Ontology
DOID:1289
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 106 in total
Gene ID Gene Symbol Description Source
50 ACO2 aconitase 2
334 APLP2 amyloid beta precursor like protein 2
387 RHOA ras homolog family member A
388 RHOB ras homolog family member B
389 RHOC ras homolog family member C
847 CAT catalase
1778 DYNC1H1 dynein cytoplasmic 1 heavy chain 1
1855 DVL1 dishevelled segment polarity protein 1
1857 DVL3 dishevelled segment polarity protein 3
2011 MARK2 microtubule affinity regulating kinase 2
Displaying entries 31 - 40 of 73 in total
Gene ID Gene Symbol Description Source
20513 Slc1a6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
21762 Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
21912 Tspan7 tetraspanin 7
21991 Tpi1 triosephosphate isomerase 1
22067 Trpc5 transient receptor potential cation channel, subfamily C, member 5
22601 Yap1 yes-associated protein 1
23969 Pacsin1 protein kinase C and casein kinase substrate in neurons 1
23970 Pacsin2 protein kinase C and casein kinase substrate in neurons 2
26357 Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group)
26442 Psma5 proteasome subunit alpha 5
Displaying entries 21 - 30 of 33 in total
Gene ID Gene Symbol Description Source
84487 Slc17a6 solute carrier family 17 member 6
94198 Psmb1 proteasome 20S subunit beta 1
157074 Sdha succinate dehydrogenase complex flavoprotein subunit A
171086 Trak2 trafficking kinesin protein 2
266767 Slc17a8 solute carrier family 17 member 8
287545 Sarm1 sterile alpha and TIR motif containing 1
296851 Pon2 paraoxonase 2
298521 Grik3 glutamate ionotropic receptor kainate type subunit 3
300733 Tspan3 tetraspanin 3
312086 Pon3 paraoxonase 3
Displaying entries 11 - 15 of 15 in total
Gene ID Gene Symbol Description Source
38742 GluRIA Glutamate receptor IA
38895 Sarm Sterile alpha and Armadillo motif
39836 st scarlet
40665 Nmdar1 NMDA receptor 1
43582 Tpi Triose phosphate isomerase
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
192309 tpi1a triosephosphate isomerase 1a
403143 sarm1 sterile alpha and TIR motif containing 1
406411 rhoaa ras homolog gene family, member Aa
406659 rhoac ras homolog gene family, member Ac
407667 asic4b acid-sensing (proton-gated) ion channel family member 4b
407668 asic4a acid-sensing (proton-gated) ion channel family member 4a
407669 asic2 acid-sensing (proton-gated) ion channel 2
407670 asic1c acid-sensing (proton-gated) ion channel 1c
407672 asic1b acid-sensing (proton-gated) ion channel 1b
436718 rhocb ras homolog family member Cb
Displaying all 3 entries
Gene ID Gene Symbol Description Source Organism
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
100038162 tpi1 triosephosphate isomerase 1 Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
173064 ced-1 Cell death abnormality protein 1
173631 ptc-3 Protein patched homolog 3
174274 ptc-1 Protein patched homolog 1;SSD domain-containing protein
175502 tir-1 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;NAD(+) hydrolase tir-1;Sterile alpha and TIR motif-containing protein 1
176204 glr-1 Glutamate receptor 1
176291 eat-4 Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4
176441 vglu-2 Major facilitator superfamily (MFS) profile domain-containing protein
176442 vglu-3 putative vesicular glutamate transporter vglu-3
177882 glt-3 Putative sodium-dependent excitatory amino acid transporter glt-3
180783 apl-1 Amyloid-beta-like protein
Displaying all 10 entries
Gene ID Gene Symbol Description Source
851013 ACO1 aconitate hydratase ACO1
851620 TPI1 triose-phosphate isomerase TPI1
853173 MTM1 Mtm1p
853770 BUD2 GTPase-activating protein BUD2
853792 OSI1 Osi1p
854943 NTE1 lysophospholipase
855392 FIG4 phosphatidylinositol-3,5-bisphosphate 5-phosphatase
855897 HRR25 serine/threonine protein kinase HRR25
856294 RHO1 Rho family GTPase RHO1
856422 RPN1 proteasome regulatory particle base subunit RPN1

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