neurodegenerative disease

Summary
Synonym
  • degenerative disease
Definition
A central nervous system disease that results in the progressive deterioration of function or structure of neurons.
Super Class
central nervous system disease
Disease Ontology
DOID:1289
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 91 - 100 of 106 in total
Gene ID Gene Symbol Description Source
57084 SLC17A6 solute carrier family 17 member 6
64919 BCL11B BCL11 transcription factor B
66008 TRAK2 trafficking kinesin protein 2
79633 FAT4 FAT atypical cadherin 4
84465 MEGF11 multiple EGF like domains 11
84466 MEGF10 multiple EGF like domains 10
84842 HPDL 4-hydroxyphenylpyruvate dioxygenase like
92935 MARS2 methionyl-tRNA synthetase 2, mitochondrial
120892 LRRK2 leucine rich repeat kinase 2
123099 DEGS2 delta 4-desaturase, sphingolipid 2
Displaying entries 61 - 70 of 73 in total
Gene ID Gene Symbol Description Source
224826 Ubr2 ubiquitin protein ligase E3 component n-recognin 2
226778 Mark1 MAP/microtubule affinity regulating kinase 1
229279 Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3
230598 Nrdc nardilysin convertase
232944 Mark4 MAP/microtubule affinity regulating kinase 4
233908 Fus fused in sarcoma
237868 Sarm1 sterile alpha and HEAT/Armadillo motif containing 1
241113 Prkag3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit
242607 Slc1a7 solute carrier family 1 (glutamate transporter), member 7
260302 Gga3 golgi associated, gamma adaptin ear containing, ARF binding protein 3
Displaying entries 11 - 20 of 33 in total
Gene ID Gene Symbol Description Source
29489 Dync1h1 dynein cytoplasmic 1 heavy chain 1
29559 Grik1 glutamate ionotropic receptor kainate type subunit 1
29627 Gria2 glutamate ionotropic receptor AMPA type subunit 2
29628 Gria3 glutamate ionotropic receptor AMPA type subunit 3
29629 Gria4 glutamate ionotropic receptor AMPA type subunit 4
50592 Gria1 glutamate ionotropic receptor AMPA type subunit 1
54257 Grik2 glutamate ionotropic receptor kainate type subunit 2
79250 Aco2 aconitase 2
84012 Slc1a6 solute carrier family 1 member 6
84024 Pon1 paraoxonase 1
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
31002 Appl beta amyloid protein precursor-like
31902 Gga Golgi-localized, gamma-adaptin ear containing, ARF binding protein
33627 ft fat
33658 FIG4 FIG4 phosphoinositide 5-phosphatase
35784 Nup50 Nucleoporin 50kD
35851 ptc patched
36484 AttC Attacin-C
36635 Dro Drosocin
38218 drpr draper
38419 Drs Drosomycin
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
192309 tpi1a triosephosphate isomerase 1a
403143 sarm1 sterile alpha and TIR motif containing 1
406411 rhoaa ras homolog gene family, member Aa
406659 rhoac ras homolog gene family, member Ac
407667 asic4b acid-sensing (proton-gated) ion channel family member 4b
407668 asic4a acid-sensing (proton-gated) ion channel family member 4a
407669 asic2 acid-sensing (proton-gated) ion channel 2
407670 asic1c acid-sensing (proton-gated) ion channel 1c
407672 asic1b acid-sensing (proton-gated) ion channel 1b
436718 rhocb ras homolog family member Cb
Displaying all 3 entries
Gene ID Gene Symbol Description Source Organism
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
100038162 tpi1 triosephosphate isomerase 1 Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
173064 ced-1 Cell death abnormality protein 1
173631 ptc-3 Protein patched homolog 3
174274 ptc-1 Protein patched homolog 1;SSD domain-containing protein
175502 tir-1 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;NAD(+) hydrolase tir-1;Sterile alpha and TIR motif-containing protein 1
176204 glr-1 Glutamate receptor 1
176291 eat-4 Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4
176441 vglu-2 Major facilitator superfamily (MFS) profile domain-containing protein
176442 vglu-3 putative vesicular glutamate transporter vglu-3
177882 glt-3 Putative sodium-dependent excitatory amino acid transporter glt-3
180783 apl-1 Amyloid-beta-like protein
Displaying all 10 entries
Gene ID Gene Symbol Description Source
851013 ACO1 aconitate hydratase ACO1
851620 TPI1 triose-phosphate isomerase TPI1
853173 MTM1 Mtm1p
853770 BUD2 GTPase-activating protein BUD2
853792 OSI1 Osi1p
854943 NTE1 lysophospholipase
855392 FIG4 phosphatidylinositol-3,5-bisphosphate 5-phosphatase
855897 HRR25 serine/threonine protein kinase HRR25
856294 RHO1 Rho family GTPase RHO1
856422 RPN1 proteasome regulatory particle base subunit RPN1

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