neurodegenerative disease

Summary
Synonym
  • degenerative disease
Definition
A central nervous system disease that results in the progressive deterioration of function or structure of neurons.
Super Class
central nervous system disease
Disease Ontology
DOID:1289
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 71 - 80 of 106 in total
Gene ID Gene Symbol Description Source
10762 NUP50 nucleoporin 50
10903 MTMR11 myotubularin related protein 11
10908 PNPLA6 patatin like phospholipase domain containing 6
11252 PACSIN2 protein kinase C and casein kinase substrate in neurons 2
22906 TRAK1 trafficking kinesin protein 1
23062 GGA2 golgi associated, gamma adaptin ear containing, ARF binding protein 2
23098 SARM1 sterile alpha and TIR motif containing 1
23163 GGA3 golgi associated, gamma adaptin ear containing, ARF binding protein 3
23274 CLEC16A C-type lectin domain containing 16A
23435 TARDBP TAR DNA binding protein
Displaying entries 51 - 60 of 73 in total
Gene ID Gene Symbol Description Source
70827 Trak2 trafficking protein, kinesin binding 2
72961 Slc17a7 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
73182 Pear1 platelet endothelial aggregation receptor 1
74244 Atg7 autophagy related 7
94232 Ubqln4 ubiquilin 4
97064 Wwtr1 WW domain containing transcription regulator 1
108099 Prkag2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
140919 Slc17a6 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
214058 Megf11 multiple EGF-like-domains 11
216227 Slc17a8 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8
Displaying entries 11 - 20 of 33 in total
Gene ID Gene Symbol Description Source
29489 Dync1h1 dynein cytoplasmic 1 heavy chain 1
29559 Grik1 glutamate ionotropic receptor kainate type subunit 1
29627 Gria2 glutamate ionotropic receptor AMPA type subunit 2
29628 Gria3 glutamate ionotropic receptor AMPA type subunit 3
29629 Gria4 glutamate ionotropic receptor AMPA type subunit 4
50592 Gria1 glutamate ionotropic receptor AMPA type subunit 1
54257 Grik2 glutamate ionotropic receptor kainate type subunit 2
79250 Aco2 aconitase 2
84012 Slc1a6 solute carrier family 1 member 6
84024 Pon1 paraoxonase 1
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
31002 Appl beta amyloid protein precursor-like
31902 Gga Golgi-localized, gamma-adaptin ear containing, ARF binding protein
33627 ft fat
33658 FIG4 FIG4 phosphoinositide 5-phosphatase
35784 Nup50 Nucleoporin 50kD
35851 ptc patched
36484 AttC Attacin-C
36635 Dro Drosocin
38218 drpr draper
38419 Drs Drosomycin
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
192309 tpi1a triosephosphate isomerase 1a
403143 sarm1 sterile alpha and TIR motif containing 1
406411 rhoaa ras homolog gene family, member Aa
406659 rhoac ras homolog gene family, member Ac
407667 asic4b acid-sensing (proton-gated) ion channel family member 4b
407668 asic4a acid-sensing (proton-gated) ion channel family member 4a
407669 asic2 acid-sensing (proton-gated) ion channel 2
407670 asic1c acid-sensing (proton-gated) ion channel 1c
407672 asic1b acid-sensing (proton-gated) ion channel 1b
436718 rhocb ras homolog family member Cb
Displaying all 3 entries
Gene ID Gene Symbol Description Source Organism
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
100038162 tpi1 triosephosphate isomerase 1 Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
173064 ced-1 Cell death abnormality protein 1
173631 ptc-3 Protein patched homolog 3
174274 ptc-1 Protein patched homolog 1;SSD domain-containing protein
175502 tir-1 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;NAD(+) hydrolase tir-1;Sterile alpha and TIR motif-containing protein 1
176204 glr-1 Glutamate receptor 1
176291 eat-4 Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4
176441 vglu-2 Major facilitator superfamily (MFS) profile domain-containing protein
176442 vglu-3 putative vesicular glutamate transporter vglu-3
177882 glt-3 Putative sodium-dependent excitatory amino acid transporter glt-3
180783 apl-1 Amyloid-beta-like protein
Displaying all 10 entries
Gene ID Gene Symbol Description Source
851013 ACO1 aconitate hydratase ACO1
851620 TPI1 triose-phosphate isomerase TPI1
853173 MTM1 Mtm1p
853770 BUD2 GTPase-activating protein BUD2
853792 OSI1 Osi1p
854943 NTE1 lysophospholipase
855392 FIG4 phosphatidylinositol-3,5-bisphosphate 5-phosphatase
855897 HRR25 serine/threonine protein kinase HRR25
856294 RHO1 Rho family GTPase RHO1
856422 RPN1 proteasome regulatory particle base subunit RPN1

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