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Standards Ontologies Notations
Parkinson's disease

Summary
Synonym
  • Parkinson disease
  • paralysis agitans
Definition
A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.
Super Class
synucleinopathy
Disease Ontology
DOID:14330
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
OMIM
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 131 - 140 of 180 in total
Gene ID Gene Symbol Description Source
10013 HDAC6 histone deacetylase 6
10059 DNM1L dynamin 1 like
10099 TSPAN3 tetraspanin 3
10114 HIPK3 homeodomain interacting protein kinase 3
10133 OPTN optineurin
10298 PAK4 p21 (RAC1) activated kinase 4
10891 PPARGC1A PPARG coactivator 1 alpha
11076 TPPP tubulin polymerization promoting protein
11315 PARK7 Parkinsonism associated deglycase
22848 AAK1 AP2 associated kinase 1
Displaying entries 31 - 40 of 146 in total
Gene ID Gene Symbol Description Source
14466 Gba1 glucosylceramidase beta 1
14563 Gdf5 growth differentiation factor 5
14573 Gdnf glial cell line derived neurotrophic factor
14751 Gpi1 glucose-6-phosphate isomerase 1
14763 Gpr37 G protein-coupled receptor 37
14824 Grn granulin
14873 Gsto1 glutathione S-transferase omega 1
14969 H2-Eb1 histocompatibility 2, class II antigen E beta
15168 Hcn3 hyperpolarization-activated, cyclic nucleotide-gated K+ 3
15185 Hdac6 histone deacetylase 6
Displaying entries 11 - 20 of 82 in total
Gene ID Gene Symbol Description Source
24598 Nos1 nitric oxide synthase 1
24613 Oprd1 opioid receptor, delta 1
24644 Pgk1 phosphoglycerate kinase 1
24787 Sod2 superoxide dismutase 2
25033 Sstr1 somatostatin receptor 1
25085 Th tyrosine hydroxylase
25149 Esr2 estrogen receptor 2
25195 Drd5 dopamine receptor D5
25233 Akt2 AKT serine/threonine kinase 2
25313 Egf epidermal growth factor
Displaying entries 1 - 10 of 25 in total
Gene ID Gene Symbol Description Source
31248 sgg shaggy
31399 Torsin torsin
31718 Tbh Tyramine beta hydroxylase
31806 Ogg1 8-oxoguanine DNA glycosylase
33007 Dop2R Dopamine 2-like receptor
33461 Pgk Phosphoglycerate kinase
35851 ptc patched
35886 Pgi Phosphoglucose isomerase
36232 Sod3 Superoxide dismutase 3
37191 5-HT1B 5-hydroxytryptamine (serotonin) receptor 1B
Displaying all 9 entries
Gene ID Gene Symbol Description Source
114549 ache acetylcholinesterase (Yt blood group)
436629 nus1 NUS1 dehydrodolichyl diphosphate synthase subunit
437021 tspan36 tetraspanin 36
494492 slc17a6a solute carrier family 17 member 6a
560788 parp1 poly (ADP-ribose) polymerase 1
563467 slc17a8 solute carrier family 17 member 8
768121 foxo1a forkhead box O1 a
100004455 epoa erythropoietin a
100149756 slc17a6b solute carrier family 17 member 6b
Displaying all 7 entries
Gene ID Gene Symbol Description Source Organism
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
398763 agtr1.L angiotensin II receptor type 1 L homeolog Xenopus laevis (African clawed frog)
399170 akt1.S AKT serine/threonine kinase 1 S homeolog Xenopus laevis (African clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
108705891 drd5.S dopamine receptor D5 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 26 in total
Gene ID Gene Symbol Description Source
171965 pgk-1 putative phosphoglycerate kinase
172105 unc-38 Acetylcholine receptor subunit alpha-type unc-38
172150 unc-63 Acetylcholine receptor subunit alpha-type unc-63
173574 gba-1 Putative glucosylceramidase 1
174274 ptc-1 Protein patched homolog 1;SSD domain-containing protein
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175076 ace-3 Carboxylic ester hydrolase
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176291 eat-4 Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
850370 PGK1 phosphoglycerate kinase
850721 SMF3 putative divalent metal ion transporter SMF3
851013 ACO1 aconitate hydratase ACO1
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
852351 AKL1 serine/threonine protein kinase AKL1
852470 SMY2 Smy2p
852495 PGI1 glucose-6-phosphate isomerase
852806 HSF1 stress-responsive transcription factor HSF1
853071 TIF4631 translation initiation factor eIF4G
853300 YAK1 serine/threonine protein kinase YAK1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024