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Standards Ontologies Notations
Parkinson's disease

Summary
Synonym
  • Parkinson disease
  • paralysis agitans
Definition
A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.
Super Class
synucleinopathy
External Links
Disease Ontology
DOID:14330
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
OMIM
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 180 in total
Gene ID Gene Symbol Description Source
2 A2M alpha-2-macroglobulin
25 ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
43 ACHE acetylcholinesterase (Yt blood group)
50 ACO2 aconitase 2
111 ADCY5 adenylate cyclase 5
131 ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
142 PARP1 poly(ADP-ribose) polymerase 1
157 GRK3 G protein-coupled receptor kinase 3
185 AGTR1 angiotensin II receptor type 1
207 AKT1 AKT serine/threonine kinase 1
Displaying entries 131 - 140 of 146 in total
Gene ID Gene Symbol Description Source
225583 Minar2 membrane integral NOTCH2 associated receptor 2
226169 Pprc1 peroxisome proliferative activated receptor, gamma, coactivator-related 1
226304 Npbwr1 neuropeptides B/W receptor 1
227331 Gigyf2 GRB10 interacting GYF protein 2
230861 Eif4g3 eukaryotic translation initiation factor 4 gamma, 3
231580 Gak cyclin G associated kinase
232345 A2m alpha-2-macroglobulin
237038 Nox1 NADPH oxidase 1
241656 Pak5 p21 (RAC1) activated kinase 5
245860 Atg9a autophagy related 9A
Displaying entries 51 - 60 of 82 in total
Gene ID Gene Symbol Description Source
81646 Creb1 cAMP responsive element binding protein 1
81728 Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2
83516 Ppargc1a PPARG coactivator 1 alpha
83529 Vdac1 voltage-dependent anion channel 1
83567 Mchr1 melanin-concentrating hormone receptor 1
83613 Nefl neurofilament light chain
83817 Ache acetylcholinesterase
84027 Gsk3b glycogen synthase kinase 3 beta
84487 Slc17a6 solute carrier family 17 member 6
85238 Synj1 synaptojanin 1
Displaying entries 1 - 10 of 25 in total
Gene ID Gene Symbol Description Source
31248 sgg shaggy
31399 Torsin torsin
31718 Tbh Tyramine beta hydroxylase
31806 Ogg1 8-oxoguanine DNA glycosylase
33007 Dop2R Dopamine 2-like receptor
33461 Pgk Phosphoglycerate kinase
35851 ptc patched
35886 Pgi Phosphoglucose isomerase
36232 Sod3 Superoxide dismutase 3
37191 5-HT1B 5-hydroxytryptamine (serotonin) receptor 1B
Displaying all 9 entries
Gene ID Gene Symbol Description Source
114549 ache acetylcholinesterase (Yt blood group)
436629 nus1 NUS1 dehydrodolichyl diphosphate synthase subunit
437021 tspan36 tetraspanin 36
494492 slc17a6a solute carrier family 17 member 6a
560788 parp1 poly (ADP-ribose) polymerase 1
563467 slc17a8 solute carrier family 17 member 8
768121 foxo1a forkhead box O1 a
100004455 epoa erythropoietin a
100149756 slc17a6b solute carrier family 17 member 6b
Displaying all 7 entries
Gene ID Gene Symbol Description Source Organism
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
398763 agtr1.L angiotensin II receptor type 1 L homeolog Xenopus laevis (African clawed frog)
399170 akt1.S AKT serine/threonine kinase 1 S homeolog Xenopus laevis (African clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
108705891 drd5.S dopamine receptor D5 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 26 in total
Gene ID Gene Symbol Description Source
171965 pgk-1 putative phosphoglycerate kinase
172105 unc-38 Acetylcholine receptor subunit alpha-type unc-38
172150 unc-63 Acetylcholine receptor subunit alpha-type unc-63
173574 gba-1 Putative glucosylceramidase 1
174274 ptc-1 Protein patched homolog 1;SSD domain-containing protein
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175076 ace-3 Carboxylic ester hydrolase
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176291 eat-4 Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
850370 PGK1 phosphoglycerate kinase
850721 SMF3 putative divalent metal ion transporter SMF3
851013 ACO1 aconitate hydratase ACO1
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
852351 AKL1 serine/threonine protein kinase AKL1
852470 SMY2 Smy2p
852495 PGI1 glucose-6-phosphate isomerase
852806 HSF1 stress-responsive transcription factor HSF1
853071 TIF4631 translation initiation factor eIF4G
853300 YAK1 serine/threonine protein kinase YAK1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024