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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
multiple sclerosis
Summary
- Synonym
-
- Generalized multiple sclerosis
- insular sclerosis
- Definition
- A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.
- Super Class
- autoimmune disease of central nervous system demyelinating disease
External Links
- Disease Ontology
- DOID:2377
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- GARD
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 3481 | IGF2 | insulin like growth factor 2 | |
| 3559 | IL2RA | interleukin 2 receptor subunit alpha | |
| 3565 | IL4 | interleukin 4 | |
| 3566 | IL4R | interleukin 4 receptor | |
| 3569 | IL6 | interleukin 6 | |
| 3596 | IL13 | interleukin 13 | |
| 3605 | IL17A | interleukin 17A | |
| 3663 | IRF5 | interferon regulatory factor 5 | |
| 4099 | MAG | myelin associated glycoprotein | |
| 4155 | MBP | myelin basic protein |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 12774 | Ccr5 | C-C motif chemokine receptor 5 | |
| 12799 | Cnp | 2',3'-cyclic nucleotide 3' phosphodiesterase | |
| 12842 | Col1a1 | collagen, type I, alpha 1 | |
| 13010 | Cst3 | cystatin C | |
| 13030 | Ctsb | cathepsin B | |
| 14102 | Fas | Fas cell surface death receptor | |
| 14103 | Fasl | Fas ligand | |
| 14396 | Gabra3 | gamma-aminobutyric acid type A receptor subunit alpha 3 | |
| 14473 | Gc | vitamin D binding protein | |
| 14823 | Grm8 | glutamate receptor, metabotropic 8 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 32158 | cac | cacophony | |
| 36585 | beta4GalNAcTA | beta1,4-N-acetylgalactosaminyltransferase A | |
| 39443 | Ptp69D | Protein tyrosine phosphatase 69D | |
| 39984 | Grd | Glycine receptor | |
| 41625 | Ace | Acetylcholine esterase | |
| 41840 | Hsc70-4 | Heat shock protein 70 cognate 4 | |
| 42490 | Mvl | Malvolio | |
| 43222 | Tl | Toll | |
| 43275 | Ser | Serrate | |
| 43425 | beta4GalNAcTB | beta1,4-N-acetylgalactosaminyltransferase B |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 114549 | ache | acetylcholinesterase (Yt blood group) | |
| 140421 | jag1a | jagged canonical Notch ligand 1a | |
| 393912 | b4galt6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | |
| 406411 | rhoaa | ras homolog gene family, member Aa | |
| 406659 | rhoac | ras homolog gene family, member Ac | |
| 555941 | cacna1ba | calcium channel, voltage-dependent, N type, alpha 1B subunit, a | |
| 724080 | b4galt5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | |
| 100006041 | rhoab | ras homolog gene family, member Ab |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 446703 | b4galt5.L | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 L homeolog | Xenopus laevis (African clawed frog) | |
| 548965 | b4galt6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | Xenopus tropicalis (tropical clawed frog) | |
| 549139 | b4galt5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | Xenopus tropicalis (tropical clawed frog) | |
| 779435 | b4galt6.L | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 L homeolog | Xenopus laevis (African clawed frog) | |
| 108695277 | b4galt6.S | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 S homeolog | Xenopus laevis (African clawed frog) | |
| 108702589 | b4galt5.S | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 175076 | ace-3 | Carboxylic ester hydrolase | |
| 176282 | lin-12 | lin-12/Notch intracellular domain | |
| 176286 | glp-1 | glp-1/Notch intracellular domain | |
| 177044 | smf-3 | NRAMP-like transporter smf-3 | |
| 177372 | cpi-1 | Cystatin cpi-1 | |
| 178748 | zmp-3 | Matrix metalloproteinase-C | |
| 179053 | cpr-4 | Cathepsin B-like cysteine proteinase 4 | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180033 | cpr-3 | Cathepsin B-like cysteine proteinase 3 | |
| 180349 | grd-2 | Ground-like domain-containing protein |
