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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
asthma
Summary
- Synonym
-
- bronchial hyperreactivity
- chronic obstructive asthma
- chronic obstructive asthma with acute exacerbation
- chronic obstructive asthma with status asthmaticus
- Definition
- A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.
- Super Class
- bronchial disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 57105 | CYSLTR2 | cysteinyl leukotriene receptor 2 | |
| 57628 | DPP10 | dipeptidyl peptidase like 10 | |
| 59067 | IL21 | interleukin 21 | |
| 60482 | SLC5A7 | solute carrier family 5 member 7 | |
| 64127 | NOD2 | nucleotide binding oligomerization domain containing 2 | |
| 64805 | P2RY12 | purinergic receptor P2Y12 | |
| 80332 | ADAM33 | ADAM metallopeptidase domain 33 | |
| 81793 | TLR10 | toll like receptor 10 | |
| 94101 | ORMDL1 | ORMDL sphingolipid biosynthesis regulator 1 | |
| 119391 | GSTO2 | glutathione S-transferase omega 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 12064 | Bdnf | brain derived neurotrophic factor | |
| 12168 | Bmpr2 | bone morphogenetic protein receptor type 2 | |
| 12266 | C3 | complement component 3 | |
| 12267 | C3ar1 | complement component 3a receptor 1 | |
| 12273 | C5ar1 | complement component 5a receptor 1 | |
| 12475 | Cd14 | CD14 antigen | |
| 12477 | Ctla4 | cytotoxic T-lymphocyte-associated protein 4 | |
| 12487 | Cd28 | CD28 antigen | |
| 12524 | Cd86 | CD86 antigen | |
| 12550 | Cdh1 | cadherin 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24180 | Agtr1a | angiotensin II receptor, type 1a | |
| 24182 | Agtr2 | angiotensin II receptor, type 2 | |
| 24225 | Bdnf | brain-derived neurotrophic factor | |
| 24232 | C3 | complement C3 | |
| 24255 | Cftr | CF transmembrane conductance regulator | |
| 24260 | Chrm3 | cholinergic receptor, muscarinic 3 | |
| 24310 | Ace | angiotensin I converting enzyme | |
| 24464 | Hp | haptoglobin | |
| 24493 | Il1a | interleukin 1 alpha | |
| 24598 | Nos1 | nitric oxide synthase 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31926 | Idgf4 | Imaginal disc growth factor 4 | |
| 34091 | Spn28Dc | Serpin 28Dc | |
| 34189 | Acer | Angiotensin-converting enzyme-related | |
| 34805 | Ance | Angiotensin converting enzyme | |
| 34978 | Idgf1 | Imaginal disc growth factor 1 | |
| 34979 | Idgf2 | Imaginal disc growth factor 2 | |
| 34981 | Idgf3 | Imaginal disc growth factor 3 | |
| 35334 | CarT | Carcinine transporter | |
| 36417 | Balat | Beta-alanine transporter | |
| 36428 | Mdr49 | Multi drug resistance 49 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30682 | vegfaa | vascular endothelial growth factor Aa | |
| 58133 | ngfb | nerve growth factor b (beta polypeptide) | |
| 114424 | cdh1 | cadherin 1, type 1, E-cadherin (epithelial) | |
| 387303 | gbgt1l4 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4 | |
| 394082 | slc18a3b | solute carrier family 18 member 3b | |
| 406411 | rhoaa | ras homolog gene family, member Aa | |
| 406659 | rhoac | ras homolog gene family, member Ac | |
| 436718 | rhocb | ras homolog family member Cb | |
| 447881 | gbgt1l3 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3 | |
| 554230 | kdr | kinase insert domain receptor (a type III receptor tyrosine kinase) |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 373580 | crhr1.2.S | corticotropin releasing hormone receptor 1, gene 2 S homeolog | Xenopus laevis (African clawed frog) | |
| 397750 | hmgcr.L | 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog | Xenopus laevis (African clawed frog) | |
| 397778 | tgfb1.L | transforming growth factor beta 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 399298 | ntf3.L | neurotrophin 3 L homeolog | Xenopus laevis (African clawed frog) | |
| 495825 | abo.3.L | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) L homeolog | Xenopus laevis (African clawed frog) | |
| 549437 | abo.3 | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 3 | Xenopus tropicalis (tropical clawed frog) | |
| 549858 | abo.2 | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 | Xenopus tropicalis (tropical clawed frog) | |
| 550054 | abo | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 1 | Xenopus tropicalis (tropical clawed frog) | |
| 100144634 | ace | angiotensin I converting enzyme | Xenopus tropicalis (tropical clawed frog) | |
| 100337618 | cdh1.S | cadherin 1, type 1 S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 180841 | gnrr-4 | G-protein coupled receptors family 1 profile domain-containing protein | |
| 181288 | pxn-2 | Peroxidasin homolog pxn-2 | |
| 181326 | pgp-3 | Multidrug resistance protein pgp-3 | |
| 181489 | adm-2 | Disintegrin and metalloproteinase domain-containing protein adm-2 | |
| 186632 | ver-4 | Tyrosine-protein kinase receptor ver-4 | |
| 191484 | pxn-1 | Peroxidasin homolog pxn-1 | |
| 266823 | parp-1 | Poly [ADP-ribose] polymerase;Poly [ADP-ribose] polymerase 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850462 | GIT1 | Git1p | |
| 851171 | HMG2 | hydroxymethylglutaryl-CoA reductase (NADPH) HMG2 | |
| 851977 | CTS2 | putative chitinase | |
| 853671 | STE6 | ATP-binding cassette a-factor transporter STE6 | |
| 853978 | NFT1 | putative multidrug transporter NFT1 | |
| 854394 | STE13 | Ste13p | |
| 854900 | HMG1 | hydroxymethylglutaryl-CoA reductase (NADPH) HMG1 | |
| 856294 | RHO1 | Rho family GTPase RHO1 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001426 | Non-Mendelian inheritance |
| HP:0000006 | Autosomal dominant inheritance |
| HP:0002099 | Asthma |
