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systemic lupus erythematosus
Summary
- Synonym
-
- Lupus Erythematosus, systemic
- SLE - Lupus Erythematosus, systemic
- disseminated lupus erythematosus
- Definition
- A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.
- Super Class
- connective tissue disease lupus erythematosus
External Links
- Disease Ontology
- DOID:9074
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- ORDO
- GARD
- MGI genotype (from TogoID)
-
- 4939884
- 5488500
- 5486338
- 5478500
- 5462253
- 5440213
- 5427085
- 4950056
- 4939894
- 5488510
- 4939883
- 4462257
- 4461031
- 4417904
- 4361591
- 3850627
- 3847256
- 3843174
- 6287976
- 7703667
- 7284986
- 7284974
- 7284944
- 6400352
- 6376530
- 6287981
- 6287978
- 3842290
- 6287975
- 6287973
- 5897270
- 5617219
- 5617218
- 5526095
- 5515634
- 5514345
- 3054644
- 3624973
- 3624942
- 3618363
- 3618357
- 3615496
- 3586344
- 3586342
- 3582186
- 3624974
- 3054643
- 2675118
- 2670276
- 2670272
- 2670271
- 2653187
- 2450135
- 2448998
- 3767995
- 3841485
- 3841484
- 3836922
- 3836921
- 3836920
- 3809239
- 3803013
- 3800222
- 2384126
- 3702859
- 3689926
- 3665495
- 3663104
- 3639668
- 3628445
- 3624982
- 3624975
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 3119 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 | |
| 3123 | HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | |
| 3303 | HSPA1A | heat shock protein family A (Hsp70) member 1A | |
| 3305 | HSPA1L | heat shock protein family A (Hsp70) member 1 like | |
| 3557 | IL1RN | interleukin 1 receptor antagonist | |
| 3558 | IL2 | interleukin 2 | |
| 3586 | IL10 | interleukin 10 | |
| 3663 | IRF5 | interferon regulatory factor 5 | |
| 3818 | KLKB1 | kallikrein B1 | |
| 4153 | MBL2 | mannose binding lectin 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 12259 | C1qa | complement component 1, q subcomponent, alpha polypeptide | |
| 12268 | C4b | complement C4B (Chido blood group) | |
| 13058 | Cybb | cytochrome b-245, beta polypeptide | |
| 13419 | Dnase1 | deoxyribonuclease I | |
| 14102 | Fas | Fas cell surface death receptor | |
| 14130 | Fcgr2b | Fc receptor, IgG, low affinity IIb | |
| 17096 | Lyn | LYN proto-oncogene, Src family tyrosine kinase | |
| 17158 | Man2a1 | mannosidase 2, alpha 1 | |
| 18566 | Pdcd1 | programmed cell death 1 | |
| 19016 | Pparg | peroxisome proliferator activated receptor gamma |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| O60602 | Toll-like receptor 5 | |
| P00734 | Prothrombin | |
| P01024 | Complement C3 | |
| P01375 | Tumor necrosis factor | |
| P01911 | HLA class II histocompatibility antigen, DRB1 beta chain | |
| P01920 | HLA class II histocompatibility antigen, DQ beta 1 chain | |
| P02647 | Apolipoprotein A-I | |
| P03952 | Plasma kallikrein | |
| P04179 | Superoxide dismutase [Mn], mitochondrial | |
| P04798 | Cytochrome P450 1A1 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0002039 | Anorexia |
| HP:0001250 | Seizure |
| HP:0012378 | Fatigue |
| HP:0000716 | Depression |
| HP:0003493 | Antinuclear antibody positivity |
| HP:0001873 | Thrombocytopenia |
| HP:0000155 | Oral ulcer |
| HP:0002716 | Lymphadenopathy |
| HP:0001596 | Alopecia |
| HP:0007417 | Discoid lupus rash |
