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Standards Ontologies Notations
type 2 diabetes mellitus

Summary
Synonym
  • NIDDM
  • insulin resistance
  • non-insulin-dependent diabetes mellitus
  • type 2 diabetes
  • type II diabetes mellitus
Definition
A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Super Class
diabetes mellitus
Disease Ontology
DOID:9352
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 211 - 220 of 325 in total
Gene ID Gene Symbol Description Source
5743 PTGS2 prostaglandin-endoperoxide synthase 2
5770 PTPN1 protein tyrosine phosphatase non-receptor type 1
5789 PTPRD protein tyrosine phosphatase receptor type D
5919 RARRES2 retinoic acid receptor responder 2
5950 RBP4 retinol binding protein 4
6009 RHEB Ras homolog, mTORC1 binding
6198 RPS6KB1 ribosomal protein S6 kinase B1
6236 RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator
6324 SCN1B sodium voltage-gated channel beta subunit 1
6347 CCL2 C-C motif chemokine ligand 2
Displaying entries 1 - 10 of 249 in total
Gene ID Gene Symbol Description Source
11303 Abca1 ATP-binding cassette, sub-family A member 1
11421 Ace angiotensin I converting enzyme
11450 Adipoq adiponectin, C1Q and collagen domain containing
11491 Adam17 a disintegrin and metallopeptidase domain 17
11551 Adra2a adrenergic receptor, alpha 2a
11556 Adrb3 adrenergic receptor, beta 3
11596 Ager advanced glycosylation end product-specific receptor
11601 Angpt2 angiopoietin 2
11609 Agtr2 angiotensin II receptor, type 2
11625 Ahsg alpha-2-HS-glycoprotein
Displaying entries 1 - 10 of 166 in total
Gene ID Gene Symbol Description Source
24152 Asip agouti signaling protein
24179 Agt angiotensinogen
24182 Agtr2 angiotensin II receptor, type 2
24185 Akt1 AKT serine/threonine kinase 1
24192 Akr1b1 aldo-keto reductase family 1 member B1
24221 Avp arginine vasopressin
24225 Bdnf brain-derived neurotrophic factor
24241 Calca calcitonin-related polypeptide alpha
24296 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
24310 Ace angiotensin I converting enzyme
Displaying entries 1 - 10 of 80 in total
Gene ID Gene Symbol Description Source
31234 Pdfr Pigment-dispersing factor receptor
31248 sgg shaggy
31271 w white
31806 Ogg1 8-oxoguanine DNA glycosylase
31926 Idgf4 Imaginal disc growth factor 4
32442 Rab3-GEF Rab3 GDP-GTP exchange factor
32974 Zw Zwischenferment
33007 Dop2R Dopamine 2-like receptor
33496 lilli lilliputian
34091 Spn28Dc Serpin 28Dc
Displaying entries 11 - 18 of 18 in total
Gene ID Gene Symbol Description Source
403310 cacna1da calcium channel, voltage-dependent, L type, alpha 1D subunit, a
406731 ugt1ab UDP glucuronosyltransferase 1 family a, b
447803 pon1 paraoxonase 1
554230 kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
560788 parp1 poly (ADP-ribose) polymerase 1
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
100004455 epoa erythropoietin a
100384891 ugt1a7 UDP glucuronosyltransferase 1 family, polypeptide A7
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source Organism
373759 cnr1.S cannabinoid receptor 1 (brain) S homeolog Xenopus laevis (African clawed frog)
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
379783 akt2.L v-akt murine thymoma viral oncogene homolog 2 L homeolog Xenopus laevis (African clawed frog)
380341 pon2.L paraoxonase 2 L homeolog Xenopus laevis (African clawed frog)
394283 sdc2.S syndecan 2 S homeolog Xenopus laevis (African clawed frog)
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
398006 insr.L insulin receptor L homeolog Xenopus laevis (African clawed frog)
Displaying entries 61 - 69 of 69 in total
Gene ID Gene Symbol Description Source
181684 cpd-2 Peptidase M14 carboxypeptidase A domain-containing protein
181706 ace-1 Acetylcholinesterase 1
182513 gpx-3 Glutathione peroxidase 3
186632 ver-4 Tyrosine-protein kinase receptor ver-4
187297 poml-1 PON (paraoxonase) and MEC-6 Like
188252 lev-9 Protein lev-9
189173 W03G11.3 Putative alpha-L-fucosidase
191374 dhrr-1 G_PROTEIN_RECEP_F2_4 domain-containing protein
266823 parp-1 Poly [ADP-ribose] polymerase;Poly [ADP-ribose] polymerase 1
Displaying entries 1 - 10 of 32 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850369 ADP1 putative ATP-dependent permease ADP1
850391 NPP1 nucleotide diphosphatase/phosphodiesterase NPP1
850614 HXK1 hexokinase 1
850645 BPT1 ATP-binding cassette bilirubin transporter BPT1
850678 YBT1 bile acid-transporting ATPase YBT1
850886 ATG26 sterol 3-beta-glucosyltransferase
850979 PIG1 protein phosphatase regulator PIG1
851006 ECM38 gamma-glutamyltransferase
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
The Human Phenotype Ontology
Displaying all 4 entries
HPO ID HPO Term
HP:0000855 Insulin resistance
HP:0005978 Type II diabetes mellitus
HP:0000006 Autosomal dominant inheritance
HP:0003584 Late onset
Displaying all 6 entries
Gene ID Gene Symbol Description
2645 GCK glucokinase
2820 GPD2 glycerol-3-phosphate dehydrogenase 2
3990 LIPC lipase C, hepatic type
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
5506 PPP1R3A protein phosphatase 1 regulatory subunit 3A
6514 SLC2A2 solute carrier family 2 member 2
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024