GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **401 - 425** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism
IRF3-mediated induction of type I IFN	DNA-dependent protein kinase catalytic subunit Double-strand break repair protein MRE11 E3 ubiquitin-protein ligase DTX4 Gamma-interferon-inducible protein 16 Interferon regulatory factor 3 NACHT, LRR and PYD domains-containing protein 4 NLR family CARD domain-containing protein 3 Probable ATP-dependent RNA helicase DDX41 Serine/threonine-protein kinase TBK1 Stimulator of interferon genes protein Three-prime repair exonuclease 1 X-ray repair cross-complementing protein 5 X-ray repair cross-complementing protein 6	P12956 P13010 P49959 P78527 Q14653 Q16666 Q7RTR2 Q86WV6 Q96MN2 Q9NSU2 Q9UHD2 Q9UJV9 Q9Y2E6	ABS DDX41 DTX4 ERIS G22P1 G22P2 HNGS1 HYRC HYRC1 IFI16 IFNGIP1 IRF3 KIAA0937 MITA MRE11 MRE11A NAK NALP4 NLRC3 NLRP4 NOD3 PAN2 PRKDC PYPAF4 RNF155 RNH2 STING STING1 TBK1 TMEM173 TREX1 XRCC5 XRCC6	Homo sapiens (human)
Regulation of RUNX1 Expression and Activity	Core-binding factor subunit beta Cyclin-dependent kinase 6 G1/S-specific cyclin-D1 G1/S-specific cyclin-D2 G1/S-specific cyclin-D3 Helicase MOV-10 Protein PML Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Proto-oncogene tyrosine-protein kinase Src Runt-related transcription factor 1 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein Tyrosine-protein phosphatase non-receptor type 11	P12931 P24385 P29590 P30279 P30281 Q00534 Q01196 Q06124 Q13951 Q8NDV7 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UKV8 Q9UL18 Q9UPQ9	AGO1 AGO2 AGO3 AGO4 AML1 BCL1 CAGH26 CBFA2 CBFB CCND1 CCND2 CCND3 CDK6 CDKN6 EIF2C1 EIF2C2 EIF2C3 EIF2C4 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 MOV10 MYL PML PP8675 PRAD1 PTP2C PTPN11 RNF71 RUNX1 SHPTP2 SRC SRC1 TNRC6 TNRC6A TNRC6B TNRC6C TRIM19	Homo sapiens (human)
Activated NTRK2 signals through FYN	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Glutamate receptor ionotropic, NMDA 2B Proto-oncogene tyrosine-protein kinase Src	P12931 P23560 Q13224 Q16620	BDNF GRIN2B NMDAR2B NTRK2 SRC SRC1 TRKB	Homo sapiens (human)
Activated NTRK3 signals through PI3K	Insulin receptor substrate 1 NT-3 growth factor receptor Neurotrophin-3 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Proto-oncogene tyrosine-protein kinase Src	P12931 P20783 P27986 P35568 P42336 Q16288	GRB1 IRS1 NTF3 NTRK3 PIK3CA PIK3R1 SRC SRC1 TRKC	Homo sapiens (human)
Apoptotic cleavage of cell adhesion proteins	Cadherin-1 Caspase-3 Catenin beta-1 Desmoglein-1 Desmoglein-2 Desmoglein-3 Desmoplakin Occludin Plakophilin-1 Tight junction protein ZO-1 Tight junction protein ZO-2	P12830 P15924 P32926 P35222 P42574 Q02413 Q07157 Q13835 Q14126 Q16625 Q9UDY2	CASP3 CDH1 CDHE CDHF4 CDHF5 CDHF6 CPP32 CTNNB CTNNB1 DSG1 DSG2 DSG3 DSP OCLN PKP1 TJP1 TJP2 UVO X104 ZO1 ZO2	Homo sapiens (human)
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	Alpha-actinin-1 Alpha-parvin Beta-parvin Dual specificity testis-specific protein kinase 1 LIM and senescent cell antigen-like-containing domain protein 1 Paxillin Ras suppressor protein 1 Rho guanine nucleotide exchange factor 6	P12814 P48059 P49023 Q15052 Q15404 Q15569 Q9HBI1 Q9NVD7	ACTN1 ARHGEF6 COOL2 KIAA0006 LIMS1 MXRA2 PARVA PARVB PINCH PINCH1 PIXA PXN RSP1 RSU1 TESK1	Homo sapiens (human)
Formation of lateral plate mesoderm	Bone morphogenetic protein 4 Forkhead box protein F1 Indian hedgehog protein Sonic hedgehog protein Transcription factor GATA-4	P12644 P43694 Q12946 Q14623 Q15465	BMP2B BMP4 DVR4 FKHL5 FOXF1 FREAC1 GATA4 IHH SHH	Homo sapiens (human)
Telomere C-strand (Lagging Strand) Synthesis	Adrenocortical dysplasia protein homolog DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 Proliferating cell nuclear antigen Protection of telomeres protein 1 TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	P12004 P28340 P49005 P54274 Q15054 Q15554 Q96AP0 Q9BSI4 Q9HCU8 Q9NUX5 Q9NYB0	ACD DRIP5 KIAA0039 PCNA PIN2 PIP1 POLD POLD1 POLD2 POLD3 POLD4 POLDS POT1 PTOP RAP1 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2	Homo sapiens (human)
Processive synthesis on the C-strand of the telomere	Adrenocortical dysplasia protein homolog Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN DNA ligase 1 DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 Proliferating cell nuclear antigen Protection of telomeres protein 1 RecQ-like DNA helicase BLM TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	P12004 P18858 P28340 P49005 P54132 P54274 Q14191 Q15054 Q15554 Q96AP0 Q9BSI4 Q9HCU8 Q9NUX5 Q9NYB0	ACD BLM DRIP5 KIAA0039 LIG1 PCNA PIN2 PIP1 POLD POLD1 POLD2 POLD3 POLD4 POLDS POT1 PTOP RAP1 RECQ2 RECQ3 RECQL2 RECQL3 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 WRN	Homo sapiens (human)
Removal of the Flap Intermediate from the C-strand	Adrenocortical dysplasia protein homolog Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA replication ATP-dependent helicase/nuclease DNA2 Flap endonuclease 1 Proliferating cell nuclear antigen Protection of telomeres protein 1 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	P12004 P15927 P27694 P28340 P35244 P39748 P49005 P51530 P54274 Q14191 Q15054 Q15554 Q96AP0 Q9BSI4 Q9HCU8 Q9NUX5 Q9NYB0	ACD DNA2 DNA2L DRIP5 FEN1 KIAA0039 KIAA0083 PCNA PIN2 PIP1 POLD POLD1 POLD2 POLD3 POLD4 POLDS POT1 PTOP RAD2 RAP1 RECQ3 RECQL2 REPA1 REPA2 REPA3 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 WRN	Homo sapiens (human)
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	DNA ligase 1 DNA mismatch repair protein Mlh1 DNA mismatch repair protein Msh2 DNA mismatch repair protein Msh6 DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 Exonuclease 1 Mismatch repair endonuclease PMS2 Proliferating cell nuclear antigen Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit	P12004 P15927 P18858 P27694 P28340 P35244 P40692 P43246 P49005 P52701 P54278 Q15054 Q9HCU8 Q9UQ84	COCA2 EXO1 EXOI GTBP HEX1 KIAA0039 LIG1 MLH1 MSH2 MSH6 PCNA PMS2 PMSL2 POLD POLD1 POLD2 POLD3 POLD4 POLDS REPA1 REPA2 REPA3 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70	Homo sapiens (human)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	DNA ligase 1 DNA mismatch repair protein Mlh1 DNA mismatch repair protein Msh2 DNA mismatch repair protein Msh3 DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 Exonuclease 1 Mismatch repair endonuclease PMS2 Proliferating cell nuclear antigen Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit	P12004 P15927 P18858 P20585 P27694 P28340 P35244 P40692 P43246 P49005 P54278 Q15054 Q9HCU8 Q9UQ84	COCA2 DUC1 DUG EXO1 EXOI HEX1 KIAA0039 LIG1 MLH1 MSH2 MSH3 PCNA PMS2 PMSL2 POLD POLD1 POLD2 POLD3 POLD4 POLDS REPA1 REPA2 REPA3 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70	Homo sapiens (human)
Metabolism of polyamines	Ornithine decarboxylase S-adenosylmethionine decarboxylase proenzyme Spermidine synthase Spermine synthase	P11926 P17707 P19623 P52788	AMD AMD1 ODC1 SMS SPS1 SRM SRML1	Homo sapiens (human)
PRPP biosynthesis	Ribose-phosphate pyrophosphokinase 1 Ribose-phosphate pyrophosphokinase 2 Ribose-phosphate pyrophosphokinase 3	P11908 P21108 P60891	PRPS1 PRPS1L1 PRPS2 PRPS3 PRPSL	Homo sapiens (human)
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4	Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 2A	P11802 P42771	CDK4 CDKN2 CDKN2A MTS1	Homo sapiens (human)
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4	Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 2A	P11802 P42771	CDK4 CDKN2 CDKN2A MTS1	Homo sapiens (human)
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6	Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase inhibitor 2A	P11802 P42771 Q00534	CDK4 CDK6 CDKN2 CDKN2A CDKN6 MTS1	Homo sapiens (human)
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6	Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase inhibitor 2A	P11802 P42771 Q00534	CDK4 CDK6 CDKN2 CDKN2A CDKN6 MTS1	Homo sapiens (human)
Drug-mediated inhibition of CDK4/CDK6 activity	Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 G1/S-specific cyclin-D1 G1/S-specific cyclin-D2 G1/S-specific cyclin-D3	P11802 P24385 P30279 P30281 Q00534	BCL1 CCND1 CCND2 CCND3 CDK4 CDK6 CDKN6 PRAD1	Homo sapiens (human)
PTK6 Regulates Cell Cycle	Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 1B G1/S-specific cyclin-D1 G1/S-specific cyclin-E1 Protein-tyrosine kinase 6	P11802 P24385 P24864 P24941 P46527 Q13882	BCL1 BRK CCND1 CCNE CCNE1 CDK2 CDK4 CDKN1B CDKN2 KIP1 PRAD1 PTK6 p27	Homo sapiens (human)
Beta oxidation of octanoyl-CoA to hexanoyl-CoA	Enoyl-CoA hydratase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P11310 P30084 P40939 P55084 Q16836	ACADM ECHS1 HAD HAD1 HADH HADHA HADHB HADHSC SCHAD	Homo sapiens (human)
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA	Enoyl-CoA hydratase, mitochondrial Enoyl-[acyl-carrier-protein] reductase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P11310 P30084 P40939 P55084 Q16836 Q9BV79	ACADM ECHS1 HAD HAD1 HADH HADHA HADHB HADHSC MECR NBRF1 SCHAD	Homo sapiens (human)
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids	2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial Enoyl-CoA delta isomerase 1, mitochondrial Long-chain specific acyl-CoA dehydrogenase, mitochondrial Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P11310 P28330 P40939 P42126 P55084 Q16698	ACADL ACADM DCI DECR DECR1 ECI1 HADH HADHA HADHB SDR18C1	Homo sapiens (human)
STAT5 activation downstream of FLT3 ITD mutants	Bcl-2-like protein 1 Cyclin-dependent kinase inhibitor 1 GRB2-associated-binding protein 2 Growth factor receptor-bound protein 2 NADPH oxidase 4 Receptor-type tyrosine-protein kinase FLT3 Serine/threonine-protein kinase pim-1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein phosphatase non-receptor type 11	P11309 P36888 P38936 P42229 P51692 P62993 Q06124 Q07817 Q9NPH5 Q9UQC2	ASH BCL2L BCL2L1 BCLX CAP20 CD135 CDKN1 CDKN1A CIP1 FLK2 FLT3 GAB2 GRB2 KIAA0571 MDA6 NOX4 PIC1 PIM1 PTP2C PTPN11 RENOX SDI1 SHPTP2 STAT5 STAT5A STAT5B STK1 WAF1	Homo sapiens (human)
Acetylation	Arylamine N-acetyltransferase 1 Arylamine N-acetyltransferase 2	P11245 P18440	AAC1 AAC2 NAT1 NAT2	Homo sapiens (human)

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