GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **676 - 700** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
RAB GEFs exchange GTP for GDP on RABs	14-3-3 protein epsilon ALS2 C-terminal like Alsin Ankyrin repeat domain 27 CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated DENN domain containing 1A DENN domain containing 1B DENN domain containing 1C DENN domain containing 2A DENN domain containing 2B DENN domain containing 2C DENN domain containing 2D DENN domain containing 3 DENN domain containing 4A DENN domain containing 4B DENN domain containing 4C DENN domain containing 5B DENN domain containing 6A DENN domain containing 6B DENN domain-containing protein 5A GTPase activating protein and VPS9 domains 1 Guanine nucleotide exchange factor for Rab-3A HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 MAP kinase-activating death domain protein Protein RIC1 homolog RAB guanine nucleotide exchange factor 1 RAB39A, member RAS oncogene family RAB6B, member RAS oncogene family RAB9B, member RAS oncogene family RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase RGP1 homolog, RAB6A GEF complex partner 1 Rab GDP dissociation inhibitor alpha Rab GDP dissociation inhibitor beta Rab proteins geranylgeranyltransferase component A 1 Rab proteins geranylgeranyltransferase component A Rab-3A-interacting protein Rab3 GTPase-activating protein catalytic subunit (Fragments) Rab3 GTPase-activating protein non-catalytic subunit Rab7b, member RAS oncogene family Ras and Rab interactor 1 Ras and Rab interactor 2 Ras and Rab interactor 3 Ras and Rab interactor-like Ras-related protein Rab-10 Ras-related protein Rab-12 Ras-related protein Rab-13 Ras-related protein Rab-14 Ras-related protein Rab-18 Ras-related protein Rab-1A Ras-related protein Rab-1B Ras-related protein Rab-21 Ras-related protein Rab-27A Ras-related protein Rab-27B Ras-related protein Rab-31 Ras-related protein Rab-35 Ras-related protein Rab-3A Ras-related protein Rab-5A Ras-related protein Rab-6A Ras-related protein Rab-7a Ras-related protein Rab-8A Ras-related protein Rab-8B Ras-related protein Rab-9A Ras-related protein Rab SET binding factor 1 SET binding factor 2 Serine/threonine-protein kinase Trafficking protein particle complex 2 Trafficking protein particle complex subunit 10 Trafficking protein particle complex subunit 11 Trafficking protein particle complex subunit 12 Trafficking protein particle complex subunit 13 Trafficking protein particle complex subunit 1 Trafficking protein particle complex subunit 2-like protein Trafficking protein particle complex subunit 3 Trafficking protein particle complex subunit 4 Trafficking protein particle complex subunit 5 Trafficking protein particle complex subunit 6A Trafficking protein particle complex subunit 6B Trafficking protein particle complex subunit 8 Trafficking protein particle complex subunit 9 Trafficking protein particle complex subunit Vacuolar fusion protein MON1 homolog Vacuolar fusion protein MON1 homolog small monomeric GTPase small monomeric GTPase	A0A0G2JT78 A0A0G2JUB1 A0A0G2K089 A0A0G2K0G9 A0A0G2K1K5 A0A0G2K6J1 A0A0G2K7U7 A0A8I5ZRE4 A0A8I5ZT12 A0A8I5ZYV2 A0A8I6A009 A0A8I6A6X2 A0A8I6AAJ7 A0A8I6ACY0 A0A8I6AEI1 A0A8I6AEV4 A0A8I6ANG7 A0A8I6G3S1 A0A8J8YPH6 A1L1J8 B0BNE3 B0BNK1 B1WC06 B2RYU6 D3Z8F6 D3ZAE3 D3ZE49 D3ZES2 D3ZLQ1 D3ZMG0 D3ZP15 D3ZP73 D3ZX30 D3ZZP2 D4A224 D4A2H4 D4A3S0 D4A518 D4A544 D4A6C4 D4A7A8 E9PU02 F1LTT7 F1M9W9 F1MAQ4 G3V631 G3V7Q0 M0RAP5 M0RBQ8 M0RC99 O08873 P09527 P0C5Y8 P10536 P23640 P35280 P35281 P35284 P35286 P37727 P47196 P47197 P50398 P50399 P61107 P62260 P63012 P69735 P70550 P97680 Q2KMM2 Q5BJL8 Q5EB77 Q5M887 Q5U1Z0 Q5U1Z2 Q5U316 Q62739 Q63483 Q63484 Q69BT7 Q6AXT5 Q6GQP4 Q6NYB7 Q99NH3 Q99P74 Q99P75 Q9WVB1	AABR07042915.1 Akt1 Akt2 Akt3 Als2 Als2cl Ankrd27 Ccz1 Ccz1b Chm Chml Dennd1a Dennd1b Dennd1c Dennd2a Dennd2b Dennd2c Dennd2d Dennd3 Dennd4a Dennd4b Dennd4c Dennd5a Dennd5b Dennd6a Dennd6b Gapvd1 Gdi1 Gdi2 Gdi3 Grab Hps1 Hps4 LOC100909916 Madd Mon1a Mon1b RGD1310016 RGD1562639 RGD1564492 Rab1 Rab10 Rab12 Rab13 Rab14 Rab18 Rab1A Rab1b Rab21 Rab27 Rab27a Rab27b Rab31 Rab35 Rab38 Rab39a Rab3a Rab3gap Rab3gap1 Rab3gap2 Rab3il1 Rab3ip Rab5a Rab5b Rab5c Rab6 Rab6a Rab6b Rab7 Rab7a Rab7b Rab8 Rab8a Rab8b Rab9 Rab9a Rab9b Rabgdia Rabgef1 Rabin3 Rabin8 Rep1 Rgp1 Ric1 Rin1 Rin2 Rin3 Rinl Sbdn Sbf1 Sbf2 Trappc1 Trappc10 Trappc11 Trappc12 Trappc13 Trappc2 Trappc2l Trappc2ll1 Trappc3 Trappc4 Trappc5 Trappc6a Trappc6b Trappc8 Trappc9 Ttc15 Ulk1 Ywhae	Rattus norvegicus (Norway rat)
Adenylate cyclase inhibitory pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(olf) subunit alpha Guanine nucleotide-binding protein G(t) subunit alpha-3 adenylate cyclase	D4A3N4 F1LQT1 M0R5U4 P04897 P08753 P10824 P21932 P26769 P26770 P29348 P38406 P40146 Q03343 Q04400	Adcy1 Adcy2 Adcy3 Adcy4 Adcy5 Adcy6 Adcy7 Adcy8 Adcy9 Gnai-1 Gnai-2 Gnai-3 Gnai1 Gnai2 Gnai3 Gnal Gnat-3 Gnat3	Rattus norvegicus (Norway rat)
Activation of G protein gated Potassium channels	ATP-sensitive inward rectifier potassium channel 10 ATP-sensitive inward rectifier potassium channel 12 ATP-sensitive inward rectifier potassium channel 15 G protein-activated inward rectifier potassium channel 1 G protein-activated inward rectifier potassium channel 2 G protein-activated inward rectifier potassium channel 3 G protein-activated inward rectifier potassium channel 4 Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Inward rectifier potassium channel 16 Inward rectifier potassium channel 2 Inward rectifier potassium channel 4	A0A8I6AF64 A0A8I6GAY3 A0A8I6GLD4 D4AAI1 F2Z3T8 G3V8K2 O35353 O88871 P43425 P48548 P48550 P49655 P52188 P52190 P52191 P52287 P54311 P54313 P61954 P62882 P63077 P63219 P63251 Q63511 Q64273 Q91ZF1 Q9Z0U4	Gabbr1 Gabbr2 Girk1 Girk2 Girk3 Girk4 Gnb1 Gnb2 Gnb3 Gnb4 Gnb5 Gng10-ps1 Gng11 Gng12 Gng3 Gng4 Gng5 Gng5-ps4 Gng7 Gng8 Gng9 Gngt1 Gngt11 Gngt5 Gngt7 Gngt9 Gpr51 Irk1 Irk2 Irk3 Kab-2 Kcnj10 Kcnj12 Kcnj15 Kcnj16 Kcnj2 Kcnj3 Kcnj4 Kcnj5 Kcnj6 Kcnj7 Kcnj9 Kga	Rattus norvegicus (Norway rat)
RIP-mediated NFkB activation via ZBP1	Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Myeloid differentiation primary response protein MyD88 NF-kappa-B essential modulator NF-kappa-B essential modulator NF-kappa-B inhibitor alpha NF-kappa-B inhibitor beta NF-kappa-B inhibitor-interacting Ras-like protein 2 NFKB inhibitor interacting Ras-like 1 Nuclear factor kappa B subunit 2 RELA proto-oncogene, NF-kB subunit RNA helicase	A0A8I5ZMV7 A0A8I6ABZ7 A0A8I6AH74 A0A8I6ANR6 A0A8I6APQ3 A0A8I6G6F3 D3ZCK2 Q63746 Q6TMG5 Q6Y1S1 Q9JIA3 Q9QY78	Chuk Dhx9 Ikba Ikbb Ikbkb Ikbkg Ikkb Myd88 Nemo Nfkb2 Nfkbia Nfkbib Nkiras1 Nkiras2 Rela	Rattus norvegicus (Norway rat)
Formation of Incision Complex in GG-NER	CDK-activating kinase assembly factor MAT1 Centrin 2 Chromodomain helicase DNA binding protein 1-like Cullin 4A Cullin 4B Cyclin-H Cyclin-dependent kinase 7 (Fragment) DNA damage-binding protein 1 DNA damage-binding protein 2 E3 SUMO-protein ligase PIAS3 ERCC excision repair 1, endonuclease non-catalytic subunit ERCC excision repair 4, endonuclease catalytic subunit ERCC excision repair 5, endonuclease General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription and DNA repair factor IIH subunit TFB5 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 Poly (ADP-ribose) polymerase 2 Poly [ADP-ribose] polymerase 1 Polyubiquitin-B Polyubiquitin-C Protein inhibitor of activated STAT, 1 Replication protein A 32 kDa subunit Replication protein A subunit Replication protein A3 Ring-box 1 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 UV excision repair protein RAD23 homolog B UV excision repair protein RAD23 Ubiquitin B-like Ubiquitin carboxyl-terminal hydrolase Ubiquitin-ribosomal protein eS31 fusion protein XPA, DNA damage recognition and repair factor XPC complex subunit, DNA damage recognition and repair factor	A0A096MKI6 A0A0G2JUC8 A0A0G2JWQ0 A0A0G2K4S7 A0A8I5ZYW5 A0A8I6A5Y3 A0A8I6AH26 A0A8I6AJT7 A0A8I6G6T5 A0JN27 D3ZAQ9 D3ZEI7 D3ZK73 D3ZR08 D3ZT95 D4A3D8 D4A845 F7EX11 F7FJT3 F7FNG5 G3V749 G3V9W0 O70260 P0CG51 P27008 P51952 P61959 P62982 P63281 Q4G005 Q4KMA2 Q561R7 Q5I0H3 Q5XIF4 Q63429 Q63528 Q7TP21 Q9ESW0 Q9R1A0	Adprt Cak Cak1 Ccnh Cdk7 Cetn2 Chd1l Cul4a Cul4b Ddb1 Ddb2 Ercc1 Ercc2 Ercc3 Ercc4 Ercc5 Gtf2h1 Gtf2h2 Gtf2h3 Gtf2h5 LOC100360645 Mnat1 Mo15 Parp1 Parp2 Pias1 Pias3 Rad23a Rad23b Rbx1 Rpa1 Rpa2 Rpa3 Rps27a Smt3a Smt3h2 Sumo1 Sumo2 Sumo3 Uba80 Ubb Ubbl1 Ubc Ubce9 Ubcep1 Ubcl1 Ube2i Usp45 Xpa Xpc	Rattus norvegicus (Norway rat)
Antagonism of Activin by Follistatin	Follistatin-related protein 3 Follistatin Inhibin beta A chain Inhibin beta B chain	P17491 P18331 P21674 Q99PW7	Flrg Fst Fstl3 Inhba Inhbb	Rattus norvegicus (Norway rat)
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	Casein kinase II subunit alpha Casein kinase II subunit alpha Casein kinase II subunit beta Chaperonin containing TCP1 subunit 6B Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Phosducin-like protein Regulator of G-protein signaling 7 Regulator of G-protein signaling 9 T-complex protein 1 subunit alpha T-complex protein 1 subunit beta T-complex protein 1 subunit delta T-complex protein 1 subunit epsilon T-complex protein 1 subunit eta T-complex protein 1 subunit gamma T-complex protein 1 subunit theta T-complex protein 1 subunit zeta	A0A8I6AR12 D4ACB8 F7ELS2 F7FH41 O35353 P19139 P28480 P49803 P49805 P52287 P54311 P54313 P62882 P67874 Q5XIM9 Q63737 Q68FQ0 Q6AYJ7 Q6P502 Q7TPB1	Cct1 Cct2 Cct3 Cct4 Cct5 Cct6a Cct6b Cct7 Cct8 Ccta Cctb Ck2n Csnk2a1 Csnk2a2 Csnk2b Gnb1 Gnb2 Gnb3 Gnb4 Gnb5 LOC363658 Pdcl Rgs7 Rgs9 Tcp1	Rattus norvegicus (Norway rat)
DAG and IP3 signaling	Protein kinase C delta type Protein kinase C epsilon type	P09215 P09216	Pkcd Pkce Prkcd Prkce	Rattus norvegicus (Norway rat)
Histamine receptors	Histamine H1 receptor Histamine H2 receptor Histamine H2 receptor Histamine H3 receptor Histamine H4 receptor	F1LNK8 P25102 P31390 Q91ZY1 Q9QYN8	Hrh1 Hrh2 Hrh3 Hrh4	Rattus norvegicus (Norway rat)
Signaling by ALK	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 ALK and LTK ligand 1 ALK and LTK ligand 2 Insulin receptor substrate 1 Midkine Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Pleiotrophin SHC-transforming protein 1 Signal transducer and activator of transcription 3 Tyrosine-protein kinase JAK3 Tyrosine-protein kinase receptor Tyrosine-protein phosphatase non-receptor type 6	A0A0G2K344 B2RZ42 F1LRZ0 M0R9C8 P10686 P35570 P52631 P63090 P81718 Q5M824 Q63272 Q63787 Q63788 Q9R1S9 Q9Z1L0	Alk Alkal1 Alkal2 Fam150a Irs-1 Irs1 Jak3 LOC100910984 Mdk Pik3ca Pik3cb Pik3r1 Pik3r2 Plcg1 Ptn Ptph6 Ptpn6 Shc1 Stat3	Rattus norvegicus (Norway rat)
Cilium Assembly	Alpha-tubulin N-acetyltransferase 1	Q6MG11	Atat1 Mec17	Rattus norvegicus (Norway rat)
Toll Like Receptor 4 (TLR4) Cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Bactericidal permeability-increasing protein CD180 molecule Dynamin-1 Dynamin-2 Dynamin-3 Lipopolysaccharide-binding protein Lymphocyte antigen 86 Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain containing adaptor molecule 2 Toll-like receptor 4 Tyrosine-protein phosphatase non-receptor type	D3ZAS0 D3ZIP2 D3ZXR7 G3V6B9 P21575 P24135 P39052 Q08877 Q56DL5 Q63313 Q63691 Q6AXU0 Q9QX05	Bpi Cd14 Cd180 Dnm Dnm1 Dnm2 Dnm3 Dyn2 Dyn3 Lbp Ly86 Ly96 Plcg2 Ptpn4 Ticam2 Tlr4	Rattus norvegicus (Norway rat)
Adherens junctions interactions	Afadin Angiogenin ribonuclease 2 Cadherin 10 Cadherin 11 Cadherin 12 Cadherin 13 Cadherin 15 Cadherin 18 Cadherin 24 Cadherin 3 Cadherin 9 Cadherin-17 Cadherin-1 Cadherin-2 Cadherin-5 Cadherin-6 Cadherin-7 Cadherin-8 Cell adhesion molecule 1 Cell adhesion molecule 2 Cell adhesion molecule 3 Nectin cell adhesion molecule 1 Nectin cell adhesion molecule 2 Nectin cell adhesion molecule 3 Nectin cell adhesion molecule 4	A0A0G2K0I6 A0A8I5YBQ6 A0A8I5ZU75 A0A8I6AM66 A0A8I6G502 D3ZFQ5 D3ZTI3 F1LMI3 F1LNP8 F1LR98 F1M1A2 F1M702 F1MAH6 O35889 O54800 P55280 P55281 Q1WIM2 Q1WIM3 Q5DWV2 Q5FVC5 Q5GAM5 Q6AYP5 Q9R0T4 Q9Z1Y3	Af6 Afdn Ang Ang2 Cad7 Cadm1 Cadm2 Cadm3 Cdh1 Cdh10 Cdh11 Cdh12 Cdh13 Cdh15 Cdh17 Cdh18 Cdh2 Cdh24 Cdh3 Cdh5 Cdh6 Cdh7 Cdh8 Cdh9 Igsf4b Igsf4d Kcad Mllt4 Necl1 Necl3 Nectin1 Nectin2 Nectin3 Nectin4 Pvrl1 Pvrl2 Raa2 SynCam1	Rattus norvegicus (Norway rat)
Other interleukin signaling	Caspase-3 Interleukin-34 Macrophage colony-stimulating factor 1 receptor Macrophage colony-stimulating factor 1 Pro-interleukin-16 Receptor-type tyrosine-protein phosphatase zeta Synaptosomal-associated protein 25 Syndecan-1 Syntaxin-1A Syntaxin-3 Syntaxin-4 Syntaxin-binding protein 2 T-cell surface glycoprotein CD4 Taxilin alpha Vesicle-associated membrane protein 2	A0A8I6AF93 B2GV14 P05540 P26260 P32851 P55213 P60881 P63045 Q00495 Q08849 Q08850 Q4KM46 Q62656 Q62753 Q8JZQ0	Casp3 Cd4 Cpp32 Csf1 Csf1r Csfm Csfmr Fms IL16 Il16 Il34 Ptprz Ptprz1 Ptpz Sap Sdc1 Snap Snap25 Stx1a Stx3 Stx3a Stx4 Stx4a Stxbp2 Syb2 Synd1 Txlna Unc18b Vamp2	Rattus norvegicus (Norway rat)
Extra-nuclear estrogen signaling	72 kDa type IV collagenase Amphiregulin Betacellulin Calmodulin-3 Caveolin-1 Caveolin-2 Estrogen receptor beta Estrogen receptor Focal adhesion kinase 1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(t) subunit alpha-3 Heat shock protein HSP 90-alpha Insulin-like growth factor 1 receptor Matrilysin Matrix metalloproteinase-9 Nitric oxide synthase 3 Palmitoyltransferase ZDHHC7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Pro-epidermal growth factor Proepiregulin Proheparin-binding EGF-like growth factor Protein arginine N-methyltransferase 1 Proto-oncogene tyrosine-protein kinase Src Protransforming growth factor alpha RAC-alpha serine/threonine-protein kinase Receptor protein-tyrosine kinase SHC-transforming protein 1 Sphingosine kinase 1 Sphingosine-1-phosphate receptor 3 Striatin Stromelysin-1	A0A0G2K344 A0A8I6AQ55 F1M9D3 G3V6K6 O35346 P01134 P03957 P04897 P06211 P07522 P08753 P0DP31 P10824 P24062 P24338 P29348 P33436 P41350 P47196 P50280 P50282 P70483 P82995 Q06175 Q2IBC5 Q5M824 Q62600 Q62986 Q63009 Q63787 Q63788 Q63789 Q91V26 Q923G5 Q9WUD9 Q9Z0L5	Akt1 Areg Btc CaMIII Calm3 Cam3 Camc Cav Cav1 Cav2 Dtr Egf Egfr Erbeta Ereg Esr Esr1 Esr2 Estr Fak Fak1 Gnai-1 Gnai-2 Gnai-3 Gnai1 Gnai2 Gnai3 Gnat-3 Gnat3 Hbegf Hegfl Hrmt1l2 Hsp86 Hsp90aa1 Hspca Igf1r Mmp-7 Mmp2 Mmp3 Mmp7 Mmp9 Nos3 Nr3a1 Nr3a2 Pik3ca Pik3r1 Pik3r2 Pik3r3 Prmt1 Ptk2 S1pr3 Sdgf Serz Shc1 Sphk1 Src Strn Tgfa Zdhhc7	Rattus norvegicus (Norway rat)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	ASH2 like histone lysine methyltransferase complex subunit Core-binding factor subunit beta Erythroid transcription factor Histone H2A type 2-A Histone H2A.J Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H3.1 Histone H3.3 Histone H3 Histone H4 Histone acetyltransferase Histone deacetylase 1 Histone-lysine N-methyltransferase Protein arginine N-methyltransferase 1 RB binding protein 5, histone lysine methyltransferase complex subunit Runt-related transcription factor 1 SET domain containing 1A, histone lysine methyltransferase SET domain containing 1B, histone lysine methyltransferase SIN3 transcription regulator family member A SIN3 transcription regulator family member B WD repeat-containing protein 5 Zinc finger protein, multitype 1 [histone H3]-lysine(4) N-methyltransferase [histone H3]-lysine(4) N-methyltransferase histone acetyltransferase	A0A0G2JXI9 A0A0G2K1E3 A0A0G2K6T6 A0A8I5Y222 A0A8I5ZSA8 A0A8I5ZYY0 A0A8I6A2W1 A0A8I6A4Z1 A0A8I6A7P3 A0A8I6AFW8 A0A8I6ANV4 A0A8I6AWT3 A0A8I6G641 A0A8I6G659 A0A8I6G8L9 A0A8I6GMB2 A9UMV8 D3ZBP2 D3ZC01 D3ZJ08 D3ZTV7 D3ZVK7 D3ZXP3 D4A168 D4ACM0 F1M0L3 G3V9C7 M0RBQ5 P0CC09 P43429 P62804 P84245 Q00729 Q498M4 Q4QQW4 Q63009 Q63046 Q6LED0	Aml1 Ash2l Cbfa2 Cbfb ENSRNOG00000062927 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 Ep300 Gata1 H2ab3 H2ac10 H2ac18 H2ac4 H2afb3 H2afx H2aj H2ax H2az2 H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H3-3b H3.3b H3c13 H3f3b H4c16 H4c2 H4f16 H4ft Hdac1 Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist2h2aa3 Hist2h3c2 Hist4 Hist4h4 Hrmt1l2 Kat2b Kmt2a Kmt2b Kmt2c LOC100365043 LOC100910200 LOC120097726 LOC684797 Mll Mll1 Prmt1 Rbbp5 Runx1 Setd1a Setd1b Sin3a Sin3b Th2b Wdr5 Zfpm1	Rattus norvegicus (Norway rat)
Presynaptic depolarization and calcium channel opening	Voltage-dependent L-type calcium channel subunit beta-1 Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 Voltage-dependent L-type calcium channel subunit beta-4 Voltage-dependent N-type calcium channel subunit alpha-1B Voltage-dependent P/Q-type calcium channel subunit alpha-1A Voltage-dependent R-type calcium channel subunit alpha-1E Voltage-dependent calcium channel gamma-2 subunit Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel subunit alpha-2/delta-2 Voltage-dependent calcium channel subunit alpha-2/delta-3	D4A055 P54282 P54283 P54287 Q02294 Q07652 Q71RJ2 Q8CFG5 Q8CFG6 Q8VGC3 Q8VHW9	Cach4 Cach5 Cach6 Cacn3 Cacna1a Cacna1b Cacna1e Cacna2d2 Cacna2d3 Cacnb1 Cacnb2 Cacnb3 Cacnb4 Cacng2 Cacng4 Cacnl1a4 Cacnl1a5 Cacnl1a6 Cacnlb1 Cacnlb2 Cacnlb3 Stg	Rattus norvegicus (Norway rat)
Loss of Nlp from mitotic centrosomes	14-3-3 protein epsilon 14-3-3 protein gamma A-kinase anchoring protein 9 ALMS1, centrosome and basal body associated protein Alpha-centractin CDK5 regulatory subunit-associated protein 2 Casein kinase I isoform delta Centrin 2 Centriolar coiled-coil protein 110 Centromere protein J Centrosomal protein 131 Centrosomal protein 135 Centrosomal protein 152 Centrosomal protein 164 Centrosomal protein 192 Centrosomal protein 250 Centrosomal protein 290 Centrosomal protein 43 Centrosomal protein 72 Centrosomal protein 78 Centrosomal protein of 41 kDa Centrosomal protein of 57 kDa Centrosomal protein of 63 kDa Centrosomal protein of 70 kDa Centrosomal protein of 76 kDa Cyclin-dependent kinase 1 Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic linker associated protein 1 Cytoskeleton associated protein 5 Dynactin 3-like 1 Dynactin subunit 1 Dynactin subunit 2 Dynein light chain 1, cytoplasmic Family with sequence similarity 29, member A HAUS augmin-like complex subunit 1 HAUS augmin-like complex subunit 8 HAUS augmin-like complex, subunit 4 HAUS augmin-like complex, subunit 5 HAUS augmin-like complex, subunit 7 Heat shock protein HSP 90-alpha Microtubule-associated protein RP/EB family member 1 NEDD1 gamma-tubulin ring complex targeting factor Ninein-like Nuclear distribution protein nudE homolog 1 Ofd1 centriole and centriolar satellite protein Outer dense fiber protein 2 Pericentrin Pericentriolar material 1 Platelet-activating factor acetylhydrolase IB subunit alpha Protein phosphatase 2 scaffold subunit A alpha SFI1 centrin binding protein SHH signaling and ciliogenesis regulator SDCCAG8 SS nuclear autoantigen 1 Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase PLK4 Tubulin alpha-1A chain Tubulin alpha-4A chain Tubulin beta-4B chain Tubulin beta-5 chain Tubulin gamma-1 chain cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase type II-beta regulatory subunit non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A0G2JYQ1 A0A0G2K4Y6 A0A0G2K548 A0A0G2K929 A0A8I5ZRX6 A0A8I5ZSK7 A0A8I5ZUW5 A0A8I6A1X1 A0A8I6A567 A0A8I6A773 A0A8I6AA62 A0A8I6ACI2 A0A8I6AEZ5 A0A8I6AHQ6 A0A8I6AIV4 A0A8I6ALB1 B2GUY1 B4F7A7 D3ZAH3 D3ZI35 D3ZMY8 D3ZTG6 D3ZVQ1 D4A194 D4A3J9 D4AB06 D4AEL8 F1LP29 F1M7J7 G3V931 G3V9W0 M0R9A9 P12369 P27791 P28023 P38650 P39951 P61983 P62260 P63004 P63170 P68370 P69897 P82995 P83888 P85515 Q06486 Q4KLY0 Q4KM37 Q4V7C1 Q5BK57 Q5PQQ9 Q5XI34 Q5XIF6 Q62673 Q62871 Q66HR2 Q6AYC0 Q6AYH5 Q6AYX5 Q6P9T8 Q99PS2 Q9ES39 Q9JLH5 Q9R0A8	AABR07000222.1 Actr1a Akap9 Alms1 Azi1 Ccdc5 Ccp110 Cdc2 Cdc2a Cdk1 Cdk5rap2 Cdkn1 Cenpj Cep131 Cep135 Cep152 Cep164 Cep192 Cep250 Cep290 Cep41 Cep43 Cep57 Cep63 Cep70 Cep72 Cep76 Cep78 Cetn2 Ck1e-2 Ckap5 Clasp1 Csnk1d Csnk1e Ctrn1 Dctn1 Dctn2 Dctn3l1 Dhc1 Dnch1 Dnchc1 Dnci2 Dncic2 Dncl1 Dnclc1 Dnec1 Dyhc Dync1h1 Dync1i2 Dynll1 Fgfr1op Haus1 Haus4 Haus5 Haus6 Haus7 Haus8 Hckid Hice1 Hsp86 Hsp90aa1 Hspca LOC309692 Lis-1 Lis1 Map1c Mapre1 Nde1 Nedd1 Nek2l1 Ninl Nude Nude1 Ny-sar-48 Odf2 Odf84 Ofd1 Pafah1b1 Pafaha Pcm1 Pcnt Pin Plk Plk1 Plk4 Ppp2r1a Prkaca Prkar2b Sak Sdccag8 Sfi1 Ssna1 Tsga14 Tuba1 Tuba1a Tuba4 Tuba4a Tubb2c Tubb4b Tubb5 Tubg Tubg1 Ywhae Ywhag	Rattus norvegicus (Norway rat)
SHC1 events in ERBB2 signaling	Betacellulin Neuregulin 3 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor Protein kinase C alpha type Protein kinase C delta type Protein kinase C epsilon type Receptor protein-tyrosine kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3 SHC-transforming protein 1 Tyrosine-protein phosphatase non-receptor type 12	A0A8I5Y1H8 A0A8I6AQ55 G3V6K6 G3V7Q4 O35569 P05696 P06494 P07522 P09215 P09216 P43322 Q06175 Q5M824 Q62799 Q9Z0L5	Btc Dtr Egf Egfr Erbb2 Erbb3 Ereg Hbegf Hegfl Ndf Neu Nrg1 Nrg2 Nrg3 Ntak Pkca Pkcd Pkce Prkca Prkcd Prkce Ptpn12 Shc1	Rattus norvegicus (Norway rat)
Ion channel transport	ATPase H+ transporting V0 subunit B ATPase H+ transporting V0 subunit D1 ATPase H+ transporting V1 subunit E2 H(+)-transporting two-sector ATPase V-type proton ATPase 116 kDa subunit a 1 V-type proton ATPase 16 kDa proteolipid subunit c V-type proton ATPase subunit B, brain isoform V-type proton ATPase subunit C 1 V-type proton ATPase subunit C 2 V-type proton ATPase subunit D V-type proton ATPase subunit E 1 V-type proton ATPase subunit F V-type proton ATPase subunit G V-type proton ATPase subunit G V-type proton ATPase subunit G V-type proton ATPase subunit H V-type proton ATPase subunit S1 V-type proton ATPase subunit a V-type proton ATPase subunit a V-type proton ATPase subunit d 2 V-type proton ATPase subunit e 1 V-type proton ATPase subunit e 2 Vacuolar proton pump subunit B	A0A8I5ZND3 A0A8I5ZWI2 A0A8I6B3N3 A0A8J8XD13 D3ZJ78 D3ZTZ4 D3ZZS8 D4A133 D4A1H0 F7FFW7 O54715 P25286 P50408 P62815 P63081 Q5EB76 Q5FVI6 Q5FVL0 Q6AYE4 Q6P503 Q6PCU2 Q794C0 Q8R2H0	Aif1 Atp6ap1 Atp6b2 Atp6c Atp6ip1 Atp6l Atp6n1 Atp6s1 Atp6s14 Atp6v0a1 Atp6v0a4 Atp6v0b Atp6v0c Atp6v0d1 Atp6v0d2 Atp6v0e Atp6v0e1 Atp6v0e2 Atp6v1a Atp6v1b1 Atp6v1b2 Atp6v1c1 Atp6v1c2 Atp6v1d Atp6v1e1 Atp6v1e2 Atp6v1f Atp6v1g1 Atp6v1g2 Atp6v1g3 Atp6v1h Atpl Bat1a Cdk2ap1-ps2 Cdk2ap1-ps3 Cdk2ap1-ps4 Cdk2ap1-ps5 Cdk2ap1-ps6 Dsr1 E230034O05Rik LOC224733l-3 LOC224733l-4 LOC224733l-5 LOC224733l-6 LOC224733l-7 LOC224733l-8 Lst1 RT1-CE12 RT1-CE3 RT1-CE5 RT1-CE6 RT1-CE8 RT1-CE9 Sacm2l-ps3 Sacm2l-ps4 Sacm2l-ps5 Sacm2l-ps6 Sacm2l-ps7 Tcirg1 Tnf Vat2 Vatf Vpp1	Rattus norvegicus (Norway rat)
Fructose catabolism	Aldehyde dehydrogenase 1A1 Fructose-bisphosphate aldolase B Glycerate kinase Ketohexokinase Triokinase/FMN cyclase	P00884 P51647 Q02974 Q0VGK3 Q4KLZ6	Aldh Aldh1a1 Aldob Dak Glyctk Khk Tkfc	Rattus norvegicus (Norway rat)
Interleukin-9 signaling	Interleukin 9 receptor Interleukin 9 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK3 Tyrosine-protein kinase	A0A0G2JX93 A0A8I6AHK3 A0A8I6AM23 D4A8I9 P52631 P52632 Q62771 Q63272	Il9 Il9r Jak1 Jak3 Mgf Stat1 Stat3 Stat4 Stat5a Stat5b	Rattus norvegicus (Norway rat)
Cytosolic sensors of pathogen-associated DNA	Absent in melanoma 2 Double-strand break repair protein MRE11	D4A9W0 Q9JIM0	Aim2 Mre11 Mre11a	Rattus norvegicus (Norway rat)
MAP2K and MAPK activation	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Beta-arrestin-1 Beta-arrestin-2 Connector enhancer of kinase suppressor of Ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase KRas GTPase NRas IQ motif containing GTPase activating protein 1 Integrin beta-3 Integrin subunit alpha 2b Interleukin 17 receptor D Kinase suppressor of ras 1 Kinase suppressor of ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Phosphatidylethanolamine-binding protein 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ragulator complex protein LAMTOR3 Ras-related protein Rap-1A Ras-related protein Rap-1b Roadblock/LAMTOR2 domain-containing protein Serine/threonine-protein kinase A-Raf Talin 1 Tyrosine-protein kinase CSK Vinculin WD repeat domain-containing protein 83 non-specific serine/threonine protein kinase	A0A8I5ZQW6 A0A8I6ABG6 A0A8I6ADH7 A0A8I6AI85 A0A8I6ATH0 A0A8I6GGN2 D3ZDZ1 D3ZGQ0 F1LY04 G3V7Q7 P02680 P04937 P06399 P08644 P11345 P14056 P14480 P20171 P21708 P29066 P29067 P31044 P32577 P35213 P36506 P62836 P63086 P85972 Q01986 Q04970 Q5BLX8 Q5U204 Q62636 Q8R2H2 Q8VHF0 Q9WUD9 Q9Z1T4	A-raf Apbb1ip Araf Araf1 Arrb1 Arrb2 Braf Cnksr1 Cnksr2 Csk ENSRNOG00000066475 Erk1 Erk2 Fga Fgb Fgg Fn1 Hras Hras1 Il17rd Iqgap1 Itga2b Itgb3 Kras Kras2 Krev1 Ksr1 Ksr2 Lamtor3 Map2k1 Map2k1ip1 Map2k2 Mapk Mapk1 Mapk3 Mark3 Mek1 Mek2 Mkk2 Morg1 Nras Pbp Pebp Pebp1 Prkm1 Prkm3 Prkmk1 Prkmk2 RGD1562674 Raf Raf1 Rap1a Rap1b Src Tln1 Vcl Wdr83 Ywhab	Rattus norvegicus (Norway rat)
Urea cycle	Arginase-1 Arginase-2, mitochondrial Argininosuccinate lyase Carbamoyl-phosphate synthase [ammonia], mitochondrial Mitochondrial ornithine transporter 1 N-acetylglutamate synthase Ornithine transcarbamylase, mitochondrial Solute carrier family 25 member 2	A0A0G2K309 A0A8I6G8E8 D4A904 O08701 P00481 P07756 P07824 P20673	Arg1 Arg2 Asl Cps1 Nags Otc Slc25a15 Slc25a2	Rattus norvegicus (Norway rat)

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