GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **176 - 200** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Ribavirin ADME	Adenosine deaminase Adenosine kinase Cytosolic purine 5'-nucleotidase Equilibrative nucleoside transporter 1 Equilibrative nucleoside transporter 3 Inosine triphosphate pyrophosphatase Nucleoside diphosphate kinase A Nucleoside diphosphate kinase B Purine nucleoside phosphorylase Sodium/nucleoside cotransporter 2 Solute carrier family 28 member 3	D3ZMY7 D3ZW55 O54698 P19804 P85973 Q05982 Q62773 Q64640 Q80WK7 Q8VIH3 Q920P6	Ada Adk Cnt2 Cnt3 Ent1 Ent3 Itpa Nme1 Nme2 Np Nt5c2 Pnp Slc28a2 Slc28a3 Slc29a1 Slc29a3 Spnt	Rattus norvegicus (Norway rat)
PKR-mediated signaling	Alpha-synuclein Cellular tumor antigen p53 Cyclin-dependent kinase 1 Cytoplasmic protein DnaJ homolog subfamily C member 3 Double-stranded RNA-specific adenosine deaminase FA complementation group A FA complementation group B FA complementation group E FA complementation group F FA complementation group G FA complementation group L FA complementation group M FA core complex associated protein 100 FA core complex associated protein 24 Fanconi anemia core complex-associated protein 20 Fanconi anemia group C protein homolog Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock-related 70 kDa protein 2 ISG15 ubiquitin-like modifier Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interferon-induced, double-stranded RNA-activated protein kinase Interferon-inducible double-stranded RNA-dependent protein kinase activator A Interleukin enhancer-binding factor 2 Interleukin enhancer-binding factor 3 Microtubule-associated protein tau Mitochondrial antiviral-signaling protein NF-kappa-B essential modulator NF-kappa-B essential modulator Nucleophosmin Protein phosphatase 2 scaffold subunit A alpha RBR-type E3 ubiquitin transferase RISC-loading complex subunit TARBP2 RNA helicase Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Sphingosine kinase 1 Tripartite motif-containing 25 Tyrosine-protein phosphatase non-receptor type 2 Ubiquitin/ISG15-conjugating enzyme E2 L6 mitogen-activated protein kinase kinase	A0A0G2JWL4 A0A0G2JX93 A0A0G2K7F0 A0A8I5ZNL4 A0A8I6ABZ7 A0A8I6AGX8 A0A8I6AH74 A0A8I6ANR6 B2RZ33 D3ZAU3 D3ZDI7 D3ZE71 D3ZXL1 D4A3X3 D4A5I2 D4A9N5 D4AAA5 F1M0R6 F1M286 O35870 P0DMW0 P0DMW1 P10361 P13084 P14659 P19332 P35233 P37377 P39951 P52631 P55063 P55266 P62716 P63018 P63331 Q3SWU0 Q4QQT4 Q4V8C7 Q4V8J2 Q5XI34 Q63184 Q66HG9 Q6TMG5 Q7TP98 Q91V26 Q925D6 Q9JIL3 Q9QY78 Q9R0T3	Adar Arih1 Cdc2 Cdc2a Cdk1 Cdkn1 Chuk Dhx9 Dnajc3 Dsrad Eif2ak2 Faap100 Faap20 Faap24 Facc Fanca Fancb Fancc Fance Fancf Fancg Fancl Fancm Hsc70 Hsc73 Hsp70-1 Hsp70-2 Hsp70-3 Hspa1 Hspa1a Hspa1b Hspa1l Hspa2 Hspa8 Hst70 Ikbkb Ikbkg Ikkb Ilf2 Ilf3 Ips1 Isg15 Map2k6 Mapt Mavs Mkk6 Mtapt Nck1 Nemo Npm1 P53 P58ipk Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5a Prkr Prkra Ptpn2 RGD1564719 Snca Sphk1 Stat1 Stat3 Stat4 Tarbp2 Tau Tp53 Trim25 Ube2l6 Visa	Rattus norvegicus (Norway rat)
Signaling by PDGF	Collagen type IV alpha 1 chain Collagen type IV alpha 2 chain Collagen type IV alpha 3 chain Collagen type IV alpha 4 chain Collagen type IV alpha 5 chain Furin Osteopontin Plasminogen Platelet-derived growth factor C Platelet-derived growth factor D Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B (Fragment) Thrombospondin 1 Thrombospondin 2 Thrombospondin 3 Thrombospondin-4 Tissue-type plasminogen activator Tyrosine-protein phosphatase non-receptor type 12	A0A0G2JV24 A0A0G2K742 A0A8I5ZZ86 A0A8I6G4F0 D4A2G6 F1LRJ1 F1M6Q3 F1MA59 G3V7Q4 P08721 P19637 P20786 P23377 P28576 P49744 Q01177 Q05028 Q05030 Q9EQT1 Q9EQX6	2b7 Col4a1 Col4a2 Col4a3 Col4a4 Col4a5 Fur Furin Iegf LOC100911572 Pcsk3 Pdgfa Pdgfb Pdgfc Pdgfd Pdgfr Pdgfr1 Pdgfra Pdgfrb Plat Plg Ptpn12 Rpa1 Scdgf Scdgfb Spp-1 Spp1 Thbs1 Thbs2 Thbs3 Thbs4 Tsp-4 Tsp4	Rattus norvegicus (Norway rat)
Negative regulation of NOTCH4 signaling	RAC-alpha serine/threonine-protein kinase	P47196	Akt1	Rattus norvegicus (Norway rat)
Iron uptake and transport	Broad substrate specificity ATP-binding cassette transporter ABCG2 Ceruloplasmin Cullin 1 Cullin-associated NEDD8-dissociated protein 1 Cytoplasmic aconitate hydratase F-box/LRR-repeat protein 5 Ferritin heavy chain Ferritin light chain 1 Ferritin Ferritin Ferritin Heme oxygenase 1 Heme oxygenase 2 Hephaestin Iron-responsive element-binding protein 2 NEDD8 Natural resistance-associated macrophage protein 2 Neutrophil gelatinase-associated lipocalin Plasma membrane ascorbate-dependent reductase CYBRD1 Polyubiquitin-B Polyubiquitin-C Proton-coupled folate transporter S-phase kinase-associated protein 1 Serotransferrin Solute carrier family 22 member 17 Solute carrier family 40 member 1 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JTC9 A0A8I5Y0H0 A0A8I5ZU81 A0A8I6A5Y3 D3ZUG8 F1M5T1 O54902 P02793 P06762 P0CG51 P12346 P13635 P19132 P23711 P30152 P62982 P97536 Q5EBA8 Q5RKJ2 Q62751 Q63270 Q63429 Q6PEC4 Q71UE8 Q80W57 Q920H8 Q923U9 Q9P290	AABR07054189.1 Abcg2 Aco1 Bcrp1 Boct Boit Cand1 Cp Cul1 Cybrd1 Dct1 Dcytb Dmt1 Fbxl5 Fpn1 Fpt1 Fth Fth1 Fth1-ps5 Ftl Ftl1 Ftl1l2 Ftmt Hcp1 Heph Hmox1 Hmox2 Ireb1 Ireb2 Irebp Irp2 LOC100359668 LOC100360645 Lcn2 Nedd8 Nramp2 Pcft Rps27a Skp1 Skp1a Slc11a2 Slc22a17 Slc40a1 Slc46a1 Tf Tip120 Tip120a Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
L1CAM interactions	Acyl-protein thioesterase 2 Neural cell adhesion molecule L1 Neuromodulin Ran-binding protein 9	A0A8I5Y176 P07936 Q05695 Q9QYL8	Caml1 Gap43 L1cam Lypla2 Ranbp9	Rattus norvegicus (Norway rat)
Adenosine P1 receptors	Adenosine receptor A1 Adenosine receptor A2a Adenosine receptor A2b Adenosine receptor A3	P25099 P28647 P29276 P30543	Adora1 Adora2a Adora2b Adora3	Rattus norvegicus (Norway rat)
SUMOylation of intracellular receptors	Androgen receptor Bile acid receptor E3 SUMO-protein ligase PIAS2 E3 SUMO-protein ligase PIAS3 Estrogen receptor Glucocorticoid receptor Histone deacetylase 4 Mineralocorticoid receptor Nuclear receptor subfamily 1 group I member 2 Nuclear receptor subfamily 5 group A member 2 Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta Peroxisome proliferator-activated receptor alpha Progesterone receptor Protein inhibitor of activated STAT, 1 Protein inhibitor of activated STAT, 4 RAR-related orphan receptor A Retinoic acid receptor RXR-alpha Retinoic acid receptor, alpha SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 Steroidogenic factor 1 Thyroid hormone receptor alpha Thyroid hormone receptor beta Vitamin D3 receptor	A0A0G2JW78 A0A8I6A803 A0A8I6AJT7 B5DFF9 O70260 P06211 P06536 P13053 P15207 P18113 P22199 P37230 P50569 P61959 P63059 P63281 Q05343 Q5I0H3 Q5XIF4 Q62685 Q62735 Q62755 Q63449 Q6AZ28 Q99P99 Q9QWM1 Q9R1A7	Ar Bar C-erba-alpha Erba2 Esr Esr1 Estr Ftzf1 Fxr Grl Hdac4 Lxra Lxrb Miz1 Mlr Nr1a1 Nr1a2 Nr1c1 Nr1h2 Nr1h3 Nr1h4 Nr1i1 Nr1i2 Nr2b1 Nr3a1 Nr3c1 Nr3c2 Nr3c3 Nr3c4 Nr5a1 Nr5a2 Pgr Pias1 Pias2 Pias3 Pias4 Piasx Ppar Ppara Pxr Rara Rip14 Rora Rxra Smt3a Smt3h2 Sumo1 Sumo2 Sumo3 Thra Thrb Ubce9 Ube2i Vdr	Rattus norvegicus (Norway rat)
RHOQ GTPase cycle	ADP-ribosylation factor like GTPase 13B ARF GTPase-activating protein GIT1 ARF GTPase-activating protein GIT2 CDC42 effector protein 4 Caveolin-1 Cdc42 effector protein 1 Cdc42 effector protein 2 Cdc42-interacting protein 4 Cell division control protein 42 homolog Copine 8 Cystic fibrosis transmembrane conductance regulator DEP domain containing 1B E3 ubiquitin-protein ligase Formin-binding protein 1 Gap junction alpha-1 protein Glucose-fructose oxidoreductase domain containing 1 Golgi associated PDZ and coiled-coil motif containing IQ motif containing GTPase activating protein 1 IQ motif containing GTPase activating protein 3 Intersectin-1 Junction plakoglobin MAGUK p55 subfamily member 7 Metalloreductase STEAP3 Neutral amino acid transporter B(0) Oligophrenin-1 Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Pleckstrin homology and RhoGEF domain containing G3 Protein diaphanous homolog 3 Ragulator complex protein LAMTOR1 Ras-related protein Rab-7a Rho GTPase activating protein 1 Rho GTPase activating protein 21 Rho GTPase activating protein 32 Rho GTPase activating protein 33 Rho GTPase activating protein 5 Rho GTPase-activating protein 17 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 Rho GTPase-activating protein 7 Rho GTPase-activating protein SYDE1 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 Rho-related GTP-binding protein RhoQ SLIT-ROBO Rho GTPase-activating protein 2 Scribble planar cell polarity protein Serine/threonine-protein kinase MRCK alpha Serine/threonine-protein kinase MRCK beta Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Sodium bicarbonate cotransporter 3 Stomatin Synaptosomal-associated protein 23 Transferrin receptor protein 1 Vang-like protein Vesicle-associated membrane protein 3 non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A0G2JUP3 A0A0G2JYR5 A0A0G2K7N9 A0A8I5ZTW6 A0A8I5ZV26 A0A8I6APL5 A0A8I6GDA1 A0A8I6GLR6 A1A5P0 B1WC33 B4F767 B5DEX3 B5DF62 D3ZA21 D3ZCS4 D3ZJ25 D3ZKC8 D3ZR63 D3ZWS0 D3ZZN9 D4A208 D4A9G6 D4AA32 F1LVW7 F1MAK3 G3V7Q7 M0RDU9 O54874 O55043 O70377 P08050 P09527 P0CAX5 P34158 P35465 P41350 P63025 P81128 P97531 Q5PQP4 Q5RKL5 Q5U2Y3 Q63744 Q64303 Q66H91 Q6P0K8 Q6P791 Q7TT49 Q8CFN2 Q8R511 Q99376 Q99N37 Q9JJL4 Q9QX73 Q9R1N3 Q9WVE9 Q9Z272	Abcc7 Arhgap1 Arhgap17 Arhgap21 Arhgap26 Arhgap32 Arhgap33 Arhgap35 Arhgap5 Arhgap7 Arhgef7 Arhgef9 Arl13b Borg1 Borg5 Cav Cav1 Cdc42 Cdc42bpa Cdc42bpb Cdc42ep1 Cdc42ep2 Cdc42ep4 Cep2 Cftr Cip4 Cpne8 Cxn-43 Depdc1b Diaph3 Dlc1 Ehsh1 Fbp17 Fnbp1 Gfod1 Git1 Git2 Gja1 Gopc Grlf1 Iqgap1 Iqgap3 Itsn Itsn1 Jup Lamtor1 Mpp7 Nbc Nbc2 Nbc3 Nbcn1 Obscn Ophn1 P190A Pak1 Pak2 Pak3bp Pak4 Pg Pixb Pk428 Plekhg3 Prex1 Rab7 Rab7a Rhogap Rhoq Scrib Slc1a5 Slc4a7 Snap23 Srgap2 Stard12 Steap3 Stom Stp Syb3 Syde1 Tc10 Tfrc Trfr Trip10 Vamp3 Vangl1 Wwp2 p190ARHOGAP	Rattus norvegicus (Norway rat)
mRNA 3'-end processing	ATP-dependent RNA helicase DDX39A Aly/REF export factor Cdc40 protein Chromatin target of PRMT1 protein Cleavage and polyadenylation specific factor 1 Cleavage and polyadenylation specific factor 3 Cleavage and polyadenylation specificity factor subunit 2 Cleavage and polyadenylation specificity factor subunit 4 Cleavage and polyadenylation specificity factor subunit 5 Cleavage and polyadenylation specificity factor subunit 6 Cleavage and polyadenylation specificity factor subunit 7 Cleavage stimulation factor subunit 1 Cleavage stimulation factor subunit 2, tau variant Cleavage stimulation factor subunit 2 Cleavage stimulation factor subunit 3 DNA polymerase delta interacting protein 3 Eukaryotic initiation factor 4A-III Mago homolog B, exon junction complex subunit Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 PCF11 cleavage and polyadenylation factor subunit Poly(A) binding protein, nuclear 1 Poly(A) polymerase Polyribonucleotide 5'-hydroxyl-kinase Clp1 Pre-mRNA 3'-end-processing factor FIP1 Pre-mRNA-splicing factor SLU7 Protein CASC3 Protein mago nashi homolog RNA helicase RNA-binding protein 8A RNA-binding protein with serine-rich domain 1 RRM domain-containing protein SAP domain-containing ribonucleoprotein Serine and arginine repetitive matrix 1 Serine and arginine rich splicing factor 11 Serine and arginine rich splicing factor 3 Serine and arginine rich splicing factor 7 Serine/arginine-rich splicing factor 1 Serine/arginine-rich splicing factor 2 Serine/arginine-rich splicing factor 5 Serine/arginine-rich splicing factor 9 Spliceosome RNA helicase Ddx39b Splicing factor U2AF 26 kDa subunit Splicing factor U2AF subunit Symplekin scaffold protein THO complex subunit 2 THO complex subunit 5 homolog THO complex subunit 6 homolog THO complex subunit 7 homolog U2 small nuclear RNA auxiliary factor 1 UAP56-interacting factor UPF3B, regulator of nonsense mediated mRNA decay	A0A0G2JXM5 A0A0G2JYV2 A0A0G2K1E5 A0A0G2K8V3 A0A0G2KA08 A0A0G2QC38 A0A0U1RRP3 A0A8I5ZSN8 A0A8I5ZTR8 A0A8I5ZV21 A0A8I5ZV38 A0A8I5ZW25 A0A8I6A2P1 A0A8I6A5F1 A0A8I6A9Y1 A0A8I6ABD9 A0A8I6AFZ5 A0A8I6AMJ9 A0A8I6G751 A0A8I6GJT1 A0A8I6GMR8 A0A8J8XR33 B1WC40 B2RYC1 D4A321 F1M0X6 F1M4W7 M0RBB1 Q09167 Q27W01 Q27W02 Q3B8Q2 Q498T2 Q498U4 Q4KM65 Q56A27 Q5BJQ6 Q5FVR7 Q5PPI1 Q5PQL4 Q5U216 Q5U317 Q5XI29 Q63413 Q68FX7 Q6AY87 Q6AYK1 Q6PDU1 Q7TP17 Q7TQ84 Q80ZG5 Q8K3X0	AABR07026797.1 Alyref Bat1 Bat1a Casc3 Cbp20 Cbp80 Cdc40 Chtop Cl-4 Clp1 Cpsf1 Cpsf2 Cpsf3 Cpsf4 Cpsf5 Cpsf6 Cpsf7 Cstf1 Cstf2 Cstf2t Cstf3 Ddx39 Ddx39a Ddx39b Ddx48 Ddxl Dhx38 Eif4a3 Fip1l1 Fmip Fop Fyttd1 Hcc1 Hrs Magoh Magohb Mln51 Ncbp1 Ncbp2 Nudt21 Pabpn1 Papola Pcf11 Pdrp Poldip3 Rbm8 Rbm8a Rnps1 Sarnp Sfrs2 Sfrs5 Sfrs9 Slu7 Srrm1 Srsf1 Srsf11 Srsf2 Srsf3 Srsf5 Srsf7 Srsf9 Sympk Thoc2 Thoc5 Thoc6 Thoc7 U2af1 U2af1l4 U2af2 Uap56 Uif Upf3b wdr58	Rattus norvegicus (Norway rat)
Signal transduction by L1	Casein kinase II subunit alpha Casein kinase II subunit alpha Casein kinase II subunit beta Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibroblast growth factor receptor 1 Integrin beta-1 Integrin beta-3 Integrin subunit alpha 2b Integrin subunit alpha 5 Integrin subunit alpha 9 Integrin subunit alpha V Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Neural cell adhesion molecule 1 Neural cell adhesion molecule L1 Neuropilin-1 Ras-related C3 botulinum toxin substrate 1 Receptor protein-tyrosine kinase Serine/threonine-protein kinase PAK 1 Vav guanine nucleotide exchange factor 2	A0A0G2K1E2 A0A8I6GGN2 D3ZN51 D3ZYG0 F1LZX9 F7FH41 G3V6K6 P13596 P19139 P21708 P35465 P36506 P49134 P63086 P67874 Q01986 Q04589 Q05695 Q6RUV5 Q8R2H2 Q9QWJ9	Caml1 Ck2n Csnk2a1 Csnk2a2 Csnk2b Egfr Erk1 Erk2 Fgfr1 Flg Itga2b Itga5 Itga9 Itgav Itgb1 Itgb3 L1cam Map2k1 Map2k2 Mapk Mapk1 Mapk3 Mek1 Mek2 Mkk2 Ncam Ncam1 Nrp1 Pak1 Prkm1 Prkm3 Prkmk1 Prkmk2 Rac Rac1 Vav2	Rattus norvegicus (Norway rat)
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)	Bifunctional epoxide hydrolase 2 Cytochrome P450 1A1 Cytochrome P450 1A2 Cytochrome P450 1B1 Cytochrome P450 2C26-like Cytochrome P450 2J3 Cytochrome P450, family 2, subfamily j, polypeptide 16	A0A0G2JTQ9 A0A8I6AFV7 P00185 P04799 P51590 P80299 Q64678	Cyp1a-1 Cyp1a-2 Cyp1a1 Cyp1a2 Cyp1b1 Cyp2c66 Cyp2j16 Cyp2j3 Cyp2j9 Ephx2 LOC100912265	Rattus norvegicus (Norway rat)
Sodium-coupled phosphate cotransporters	Sodium-dependent phosphate transporter 1 Sodium-dependent phosphate transporter 2	Q63488 Q9JJP0	Pit1 Pit2 Ram1 Slc20a1 Slc20a2	Rattus norvegicus (Norway rat)
LXRs regulate gene expression linked to cholesterol transport and efflux	ATP binding cassette subfamily A member 1 G protein pathway suppressor 2 Histone deacetylase 3 Nuclear receptor co-repressor 2 Nuclear receptor coactivator Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta (Fragment) TBL1X/Y related 1 Transducin (beta)-like 1 X-linked histone acetyltransferase	A0A0G2JU91 A0A0G2JY80 A0A8I5ZLK5 A0A8I6APA0 A0A8I6G641 A0A8I6GLY5 D3ZNF4 P49743 Q05343 Q62685 Q62755 Q6P6W3	Abca1 Ep300 Gps2 Hdac3 Lxra Lxrb Ncoa1 Ncor2 Nr1h2 Nr1h3 Nr2b1 Nr2b2 Rcor-1 Rxra Rxrb Tbl1x Tbl1xr1	Rattus norvegicus (Norway rat)
PTK6 Regulates Cell Cycle	Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 1B G1/S-specific cyclin-D1 G1/S-specific cyclin-E1 Tyrosine-protein kinase	D3ZDS3 O08769 P35426 P39948 P39949 Q63699	Ccnd1 Ccne Ccne1 Cdk2 Cdk4 Cdkn1b Cdkn2 Ptk6 p27Kip1	Rattus norvegicus (Norway rat)
Breakdown of the nuclear lamina	Caspase-6 Lamin-B1 Prelamin-A/C	O35397 P48679 P70615	Casp6 Lmn1 Lmna Lmnb1 Mch2	Rattus norvegicus (Norway rat)
Heme degradation	ATP-binding cassette sub-family C member 2 Albumin Biliverdin reductase A Broad substrate specificity ATP-binding cassette transporter ABCG2 Fatty acid-binding protein, liver Glutathione S-transferase A6 Glutathione S-transferase alpha-1 Glutathione S-transferase alpha-2 Glutathione S-transferase alpha-3 Glutathione S-transferase alpha-5 Heme oxygenase 1 Heme oxygenase 2 Multidrug resistance-associated protein 1 NAD(P)-binding domain-containing protein Solute carrier organic anion transporter family member 1B2 Solute carrier organic anion transporter family member 2B1 UDP-glucuronosyltransferase 1-2 UDP-glucuronosyltransferase 1A1 UDP-glucuronosyltransferase 1A3 UDP-glucuronosyltransferase 1A5	A0A8I6A3K7 P00502 P02692 P02770 P04903 P04904 P06762 P20720 P23711 P46418 P46844 Q63120 Q64550 Q64637 Q64638 Q6AXY0 Q80W57 Q8CG09 Q9JHI3 Q9QZX8	Abcc1 Abcc2 Abcg2 Alb Bcrp1 Blvr Blvra Cmoat Cmrp ENSRNOG00000064875 Fabp1 Gsta1 Gsta2 Gsta3 Gsta5 Gsta6 Gstyc1 Gstyc2 Hmox1 Hmox2 Mrp1 Mrp2 Oatp1b2 Oatp2b1 Slc21a10 Slc21a9 Slco1b2 Slco2b1 Ugt1 Ugt1a1 Ugt1a2 Ugt1a3 Ugt1a5	Rattus norvegicus (Norway rat)
Pyrimidine catabolism	5', 3'-nucleotidase, cytosolic 5',3'-nucleotidase, mitochondrial 5'-nucleotidase, cytosolic IA 5'-nucleotidase 5'-nucleotidase Beta-ureidopropionase Dihydropyrimidinase Dihydropyrimidine dehydrogenase [NADP(+)] Thymidine phosphorylase Uridine phosphorylase Uridine phosphorylase	A0A8I5ZYY7 A0A8I6AHB0 D3ZWR1 D4A5J2 D4A9N9 F7F0D5 O89000 P21588 Q03248 Q5FVR2 Q63150	Bup1 DPD Dpyd Dpys Ecgf1 Nt5 Nt5c Nt5c1a Nt5c3a Nt5e Nt5m Nte Tymp Upb1 Upp1 Upp2	Rattus norvegicus (Norway rat)
Beta oxidation of hexanoyl-CoA to butanoyl-CoA	Enoyl-CoA hydratase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Short-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P14604 P15651 Q60587 Q64428 Q9WVK7	Acads Echs1 Had Hadh Hadha Hadhb Hadhsc Schad	Rattus norvegicus (Norway rat)
RNA Polymerase I Promoter Opening	Histone H2A type 2-A Histone H2A.J Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H3.1 Histone H3.3 Histone H3 Histone H4 Methyl-CpG binding domain protein 2 Mitogen-activated protein kinase 3 Nucleolar transcription factor 1	A0A0G2JXI9 A0A8I5ZSA8 A0A8I5ZYY0 A0A8I6A2W1 A0A8I6A7P3 A0A8I6AFW8 A0A8I6AWT3 A0A8I6G659 A9UMV8 D3ZJ08 D3ZVK7 D3ZXP3 D4A986 D4ACM0 G3V9C7 M0RBQ5 P0CC09 P21708 P25977 P62804 P84245 Q00729 Q6LED0	ENSRNOG00000062927 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 Erk1 H2ab3 H2ac10 H2ac18 H2ac4 H2afb3 H2afx H2aj H2ax H2az2 H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H3-3b H3.3b H3c13 H3f3b H4c16 H4c2 H4f16 H4ft Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist2h2aa3 Hist2h3c2 Hist4 Hist4h4 LOC100365043 LOC100910200 LOC120097726 LOC684797 Mapk3 Mbd2 Prkm3 Tcfubf Th2b Ubf-1 Ubtf	Rattus norvegicus (Norway rat)
Ciprofloxacin ADME	Albumin Broad substrate specificity ATP-binding cassette transporter ABCG2 Solute carrier family 22 member 1 Solute carrier organic anion transporter family member 1A4	O35913 P02770 Q63089 Q80W57	Abcg2 Alb Bcrp1 Oatp1a4 Oatp2 Oct1 Slc21a5 Slc22a1 Slco1a4	Rattus norvegicus (Norway rat)
Negative feedback regulation of MAPK pathway	Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 RAF proto-oncogene serine/threonine-protein kinase non-specific serine/threonine protein kinase	A0A8I6ATH0 P11345 P21708 P36506 P63086 Q01986	Braf Erk1 Erk2 Map2k1 Map2k2 Mapk Mapk1 Mapk3 Mek1 Mek2 Mkk2 Prkm1 Prkm3 Prkmk1 Prkmk2 Raf Raf1	Rattus norvegicus (Norway rat)
FLT3 Signaling	Forkhead box O3 GRB2-associated-binding protein 2 GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 10 Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase SOS Ras/Rac guanine nucleotide exchange factor 1 receptor protein-tyrosine kinase	A0A0G2JW59 A0A0G2K344 D3ZBQ1 D4A3T0 P08644 P0CE43 P20171 P47196 P47197 P62994 Q04970 Q63484 Q63787 Q9EQH1	Akt1 Akt2 Akt3 Ash Flt3 Foxo3 Gab2 Grb10 Grb2 Hras Hras1 Kras Kras2 Nras Pik3ca Pik3r1 Sos1	Rattus norvegicus (Norway rat)
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)	Dipeptidyl peptidase 4 Free fatty acid receptor 1 Gastric inhibitory polypeptide Glucose-dependent insulinotropic receptor	P14740 Q06145 Q7TQN8 Q8K3T4	Cd26 Dpp4 Ffar1 Gip Gpr119 Gpr40	Rattus norvegicus (Norway rat)
RHOJ GTPase cycle	DEP domain containing 1B Dedicator of cytokinesis 8 Inositol polyphosphate 5-phosphatase OCRL Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Ras homolog family member J Rho GTPase activating protein 1 Rho GTPase activating protein 21 Rho GTPase activating protein 32 Rho GTPase activating protein 5 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 Rho GTPase-activating protein SYDE1 Triple functional domain protein	A0A0G2JYR5 A0A0G2K7N9 A0A8I6A829 A0A8I6APL5 A0A8I6GDA1 A0A8I6GLR6 D3ZGS3 D3ZZN9 D4AA32 F1M0Z1 F1MAK3 P0CAX5 P81128 Q5RJS2 Q63787 Q63788	Arhgap1 Arhgap21 Arhgap26 Arhgap32 Arhgap35 Arhgap5 Depdc1b Dock8 Grlf1 Ocrl Ophn1 P190A Pik3r1 Pik3r2 Prex1 Rhoj Syde1 Trio p190ARHOGAP	Rattus norvegicus (Norway rat)

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