GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **201 - 225** of **1070** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism	GlyTouCan ID
APAP ADME	ATP-binding cassette sub-family C member 2 ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family C member 5 ATP-binding cassette subfamily C member 4 Aminoacylase-1A Arylamine N-acetyltransferase 1 Arylamine N-acetyltransferase 2 Broad substrate specificity ATP-binding cassette transporter ABCG2 Cytochrome P450 2E1 Cytosolic non-specific dipeptidase Glutathione S-transferase Mu 2 Glutathione S-transferase P Glutathione S-transferase theta-1 Glutathione hydrolase 1 proenzyme Glutathione hydrolase 5 proenzyme Glutathione hydrolase 6 Glutathione hydrolase 7 Multidrug resistance-associated protein 1 Sulfotransferase 1A1 Sulfotransferase 2A1 Sulfotransferase 2A2 Sulfotransferase 2A6 UDP-glucuronosyltransferase 1-6 UDP-glucuronosyltransferase 1A1 UDP-glucuronosyltransferase 1A7 UDP-glucuronosyltransferase 1A8 UDP-glucuronosyltransferase 2B15 UDP-glucuronosyltransferase 2B17 UDP-glucuronosyltransferase 2B1 UDP-glucuronosyltransferase 2B2 UDP-glucuronosyltransferase 2B37 UDP-glucuronosyltransferase 2B7 UDP-glucuronosyltransferase arylamine N-acetyltransferase	F1LTB8 F1M3J4 G3V9I5 O88563 P04906 P05182 P07314 P08010 P08430 P08541 P08542 P09875 P15709 P17988 P19488 P22789 P36511 P50235 P50297 P50298 Q01579 Q62789 Q63120 Q64550 Q64633 Q64634 Q6AYS7 Q6IE08 Q6Q0N1 Q80W57 Q8CG09 Q99MZ4 Q9QWE9 Q9QYM0	Aac1 Aac2 Abcc1 Abcc2 Abcc3 Abcc4 Abcc5 Abcg2 Acy1 Acy1a Bcrp1 Cmoat Cmoat2 Cmrp Cndp2 Cyp2e Cyp2e-1 Cyp2e1 Ggt Ggt1 Ggt5 Ggt6 Ggt7 Ggtl3 Ggtla1 Gstm2 Gstp1 Gstt1 Mlp2 Mrp1 Mrp2 Mrp3 Mrp4 Mrp5 Nat1 Nat2 Nat3 RGD1559459 Smp2a St1a1 St2a1 St2a2 Sult1a1 Sult2a1 Sult2a2 Sult2a6 Udpgtr2 Ugt1 Ugt1a1 Ugt1a6 Ugt1a7 Ugt1a7c Ugt1a8 Ugt2b Ugt2b1 Ugt2b12 Ugt2b15 Ugt2b17 Ugt2b2 Ugt2b3 Ugt2b34l1 Ugt2b36 Ugt2b37 Ugt2b4 Ugt2b5 Ugt2b6 Ugt2b7 Ugt2b8	Rattus norvegicus (Norway rat)
MDK and PTN in ALK signaling	Midkine Pleiotrophin Receptor-type tyrosine-protein phosphatase zeta Tyrosine-protein kinase receptor	F1LRZ0 P63090 Q62656 Q9R1S9	Alk Mdk Ptn Ptprz Ptprz1 Ptpz	Rattus norvegicus (Norway rat)
Elevation of cytosolic Ca2+ levels	Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 P2X purinoceptor 1 P2X purinoceptor 2 P2X purinoceptor 3 P2X purinoceptor 4 P2X purinoceptor 5 P2X purinoceptor 6 P2X purinoceptor 7 Short transient receptor potential channel 3 Transient receptor potential cation channel, subfamily C, member 7	F1LQF7 P29994 P29995 P47824 P49653 P49654 P51577 P51578 P51579 Q63269 Q64663 Q9JMI9	Insp3r Itpr1 Itpr2 Itpr3 P2rx1 P2rx2 P2rx3 P2rx4 P2rx5 P2rx6 P2rx7 P2rxl1 Trpc3 Trpc7 Trrp3	Rattus norvegicus (Norway rat)
Biosynthesis of DHA-derived SPMs	Polyunsaturated fatty acid lipoxygenase ALOX12 Polyunsaturated fatty acid lipoxygenase ALOX15 Prostaglandin G/H synthase 2	F1LQ70 P35355 Q02759	Alox12 Alox12l Alox15 Cox-2 Cox2 Ptgs2	Rattus norvegicus (Norway rat)
Histamine receptors	Histamine H1 receptor Histamine H2 receptor Histamine H2 receptor Histamine H3 receptor Histamine H4 receptor	F1LNK8 P25102 P31390 Q91ZY1 Q9QYN8	Hrh1 Hrh2 Hrh3 Hrh4	Rattus norvegicus (Norway rat)
CD28 co-stimulation	CD86 molecule Cd80 molecule GRB2-related adaptor protein 2 Proto-oncogene tyrosine-protein kinase LCK Proto-oncogene tyrosine-protein kinase Src T-cell-specific surface glycoprotein CD28 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	F1LM93 G3V671 O35531 P31042 Q01621 Q07014 Q3KR57 Q62844 Q9WUD9	Cd28 Cd80 Cd86 Fyn Grap2 Lck Lyn Src Yes1	Rattus norvegicus (Norway rat)
PECAM1 interactions	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Integrin beta-3 Integrin subunit alpha V Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Platelet endothelial cell adhesion molecule Proto-oncogene tyrosine-protein kinase LCK Proto-oncogene tyrosine-protein kinase Src Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6	F1LM93 F1LZX9 P10686 P41499 P81718 P97573 Q01621 Q07014 Q3SWT0 Q62844 Q8R2H2 Q9WUD9	Fyn Inpp5d Itgav Itgb3 Lck Lyn Pecam Pecam1 Plcg1 Ptph6 Ptpn11 Ptpn6 Ship Ship1 Src Yes1	Rattus norvegicus (Norway rat)
Cation-coupled Chloride cotransporters	Solute carrier family 12 member 1 Solute carrier family 12 member 2 Solute carrier family 12 member 3 Solute carrier family 12 member 4 Solute carrier family 12 member 5 Solute carrier family 12 member 7 Solute carrier family 12, member 6	E9PTX9 G3V6N7 P55016 P55018 Q5RK27 Q63632 Q63633	Kcc1 Kcc2 Kcc4 Nkcc2 Slc12a1 Slc12a2 Slc12a3 Slc12a4 Slc12a5 Slc12a6 Slc12a7 Tsc	Rattus norvegicus (Norway rat)
Regulation of CDH11 gene transcription	Transcription factor Sp1 Zinc finger E-box binding homeobox 2	E9PTC3 Q01714	Sp1 Zeb2	Rattus norvegicus (Norway rat)
HDL remodeling	ATP binding cassette subfamily G member 1 Albumin Apolipoprotein A-I Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Endothelial lipase Phosphatidylcholine-sterol acyltransferase Phospholipid transfer protein	E9PSP1 G3V642 G3V8D4 P02650 P02770 P04639 P06759 P18424 Q8VBX1	Abcg1 Alb Apoa1 Apoc2 Apoc3 Apoe Lcat Lipg Pltp	Rattus norvegicus (Norway rat)
Activation of BAD and translocation to mitochondria	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein theta 14-3-3 protein zeta/delta Bcl2-associated agonist of cell death Calcineurin subunit B type 1 Serine/threonine-protein phosphatase Stratifin	E2CWF0 G3V9A3 O35147 P35213 P61983 P62260 P63100 P63102 P68255 P68511	Bad Cna2 Cnb Msfs1 Ppp3cc Ppp3r1 Sfn Ywhab Ywhae Ywhag Ywhah Ywhaq Ywhaz	Rattus norvegicus (Norway rat)
Class C/3 (Metabotropic glutamate/pheromone receptors)	Extracellular calcium-sensing receptor G-protein coupled receptor family C group 6 member A Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Metabotropic glutamate receptor 1 Metabotropic glutamate receptor 2 Metabotropic glutamate receptor 3 Metabotropic glutamate receptor 4 Metabotropic glutamate receptor 5 Metabotropic glutamate receptor 6 Metabotropic glutamate receptor 7 Metabotropic glutamate receptor 8 Taste receptor type 1 member 1 Taste receptor type 1 member 2 Taste receptor type 1 member 3 Taste receptor type 2 member 106 Taste receptor type 2 member 119 Taste receptor type 2 member 120 Taste receptor type 2 member 135 Taste receptor type 2 member 136 Taste receptor type 2 member 13 Taste receptor type 2 member 140 Taste receptor type 2 member 16 Taste receptor type 2 member 38 Taste receptor type 2 member 39 Taste receptor type 2 member 3 Taste receptor type 2 member 40 Taste receptor type 2 member 41 Taste receptor type 2 member 4 Taste receptor type 2 member 7 Taste receptor type 2	D4AEI0 O88871 P23385 P31421 P31422 P31423 P31424 P35349 P35400 P48442 P70579 Q4VHE7 Q675B7 Q67ER9 Q67ES0 Q67ES2 Q67ET0 Q67ET1 Q67ET2 Q67ET3 Q67ET7 Q70VB1 Q923K1 Q9JKE7 Q9JKE9 Q9JKT7 Q9JKU0 Q9JKU1 Q9Z0R7 Q9Z0R8 Q9Z0U4	Casr Gabbr1 Gabbr2 Gpr51 Gpr70 Gpr71 Gprc1a Gprc1b Gprc1c Gprc1d Gprc1e Gprc1f Gprc1g Gprc1h Gprc2a Gprc6a Grm1 Grm2 Grm3 Grm4 Grm5 Grm6 Grm7 Grm8 Mglur1 Mglur2 Mglur3 Mglur4 Mglur5 Mglur6 Mglur7 Mglur8 Pcar1 T1r1 T1r2 T1r3 T2r16 T2r17 T2r18 T2r20 T2r38 Tas1r1 Tas1r2 Tas1r3 Tas2r1 Tas2r106 Tas2r108 Tas2r118 Tas2r119 Tas2r12 Tas2r120 Tas2r121 Tas2r126 Tas2r13 Tas2r130 Tas2r135 Tas2r136 Tas2r137 Tas2r138 Tas2r139 Tas2r140 Tas2r144 Tas2r145 Tas2r16 Tas2r18 Tas2r19 Tas2r26 Tas2r28 Tas2r3 Tas2r31 Tas2r32 Tas2r38 Tas2r39 Tas2r4 Tas2r40 Tas2r41 Tas2r6 Tas2r7 Tr1 Tr2 Tr3	Rattus norvegicus (Norway rat)	G58161NS
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	Aldo-keto reductase family 1 member C21 Aldo-keto reductase family 1, member C1 Carbonyl reductase [NADPH] 1 Cytochrome P450 family 8 subfamily B member 1 Hematopoietic prostaglandin D synthase Prostacyclin synthase Prostaglandin E synthase 2 Prostaglandin E synthase 3 Prostaglandin E synthase Prostaglandin G/H synthase 1 Prostaglandin G/H synthase 2 Prostaglandin-H2 D-isomerase Thromboxane-A synthase	D4AE56 G3V8J2 O35543 P22057 P35355 P47727 P49430 P83868 Q3MHS3 Q62969 Q63921 Q6AYQ2 Q9JHF3	Akr1c1 Akr1c21 Cbr Cbr1 Cox-1 Cox-2 Cox1 Cox2 Cyp5 Cyp5a1 Cyp8 Cyp8b1 Gsts Hpgds Hsd17b5 Pgds Pges Pig12 Ptgds Ptgds2 Ptges Ptges2 Ptges3 Ptgis Ptgs1 Ptgs2 Tbxas1 Tebp	Rattus norvegicus (Norway rat)
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein theta 14-3-3 protein zeta/delta Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 M-phase inducer phosphatase Stratifin Wee1-like protein kinase	D4ADT2 G3V9A3 P30277 P35213 P39951 P61983 P62260 P63102 P68255 P68511 Q63802	Ccnb1 Cdc2 Cdc25c Cdc2a Cdk1 Cdkn1 Msfs1 Sfn Wee1 Ywhab Ywhae Ywhag Ywhah Ywhaq Ywhaz	Rattus norvegicus (Norway rat)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	Cell division cycle protein 20 homolog Mitotic arrest deficient 2 like 1	D4ACM2 Q62623	Cdc20 Mad2l1	Rattus norvegicus (Norway rat)
Cytosolic sensors of pathogen-associated DNA	Absent in melanoma 2 Double-strand break repair protein MRE11	D4A9W0 Q9JIM0	Aim2 Mre11 Mre11a	Rattus norvegicus (Norway rat)
Interleukin-38 signaling	Interleukin-1 receptor accessory protein-like 1 Interleukin-1 receptor-like 2 Interleukin-1 Mitogen-activated protein kinase 8	D4A9I5 P49185 P59824 Q62929	Il1f10 Il1rapl1 Il1rl2 Jnk1 Mapk8 Prkm8	Rattus norvegicus (Norway rat)
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)	Potassium channel subfamily K member 1 Potassium channel subfamily K member Potassium channel subfamily K member	D4A806 G3V8R8 Q9Z2T2	Kcnk1 Kcnk6 Kcnk7	Rattus norvegicus (Norway rat)
ABO blood group biosynthesis	Galactoside alpha-(1,2)-fucosyltransferase 1 Galactoside alpha-(1,2)-fucosyltransferase 2 Histo-blood group ABO system transferase 2 Histo-blood group ABO system transferase 2	D4A7T1 Q10980 Q10984 Q8CFC4	Abo2 Fta Ftb Fut1 Fut2 Sec1	Rattus norvegicus (Norway rat)
Lectin pathway of complement activation	Collectin subfamily member 10 Ficolin-1 Ficolin-2 Mannan-binding lectin serine protease 1 Mannan-binding lectin serine protease 2 Mannose-binding protein C	D4A7F6 P08661 P57756 Q8CHN8 Q9JJS8 Q9WTS8	Colec10 Crarf Fcn1 Fcn2 Fcna Fcnb Masp1 Masp2 Masp3 Mbl2	Rattus norvegicus (Norway rat)	G49108TO G57321FI
DDX58/IFIH1-mediated induction of interferon-alpha/beta	Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Interferon regulatory factor 3 Mitochondrial antiviral-signaling protein Mitochondrial import receptor subunit TOM70 TANK-binding kinase 1	D4A7D3 F7EXX5 P34058 P82995 Q66HG9 Q75Q39	Hsp84 Hsp86 Hsp90aa1 Hsp90ab1 Hspc3 Hspca Hspcb Ips1 Irf3 Mavs Tbk1 Tomm70 Tomm70a Visa	Rattus norvegicus (Norway rat)
Methylation	Adenosylhomocysteinase Arsenite methyltransferase Catechol O-methyltransferase Cytochrome P450 1A2 Glutathione S-transferase omega-1 Methionine adenosyltransferase 2 subunit beta Methionine synthase reductase Methionine synthase Nicotinamide N-methyltransferase S-adenosylmethionine synthase isoform type-1 S-adenosylmethionine synthase isoform type-2 Thiopurine S-methyltransferase	D4A605 P04799 P10760 P13444 P18298 P22734 Q498R1 Q5U2R0 Q8VHT6 Q9Z0T0 Q9Z2Q4 Q9Z339	Ahcy Ams1 Ams2 As3mt Comt Cyp1a-2 Cyp1a2 Cyt19 Gsto1 Mat1a Mat2a Mat2b Mtr Mtrr Nnmt Tpmt	Rattus norvegicus (Norway rat)
PDH complex synthesizes acetyl-CoA from PYR	Ac1164 Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha Pyruvate dehydrogenase E1 component subunit beta, mitochondrial	D4A5G8 P08461 P26284 P49432 Q06437 Q6P6R2 Q7TQ85	Dlat Dld LOC311254 Pdha1 Pdha1l1 Pdha2 Pdhb Pdhx	Rattus norvegicus (Norway rat)
Activation of the AP-1 family of transcription factors	Cyclic AMP-dependent transcription factor ATF-2 Mapk11 protein Mitogen-activated protein kinase 10 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 8 Mitogen-activated protein kinase 9 Protein c-Fos Transcription factor Jun	D4A3U7 P12841 P17325 P21708 P49185 P49186 P49187 P63086 P70618 Q00969	Atf2 Csbp1 Csbp2 Erk1 Erk2 Fos Jnk1 Jnk2 Jnk3 Jun Mapk Mapk1 Mapk10 Mapk11 Mapk14 Mapk3 Mapk8 Mapk9 Prkm1 Prkm10 Prkm3 Prkm8 Prkm9 Rjg-9	Rattus norvegicus (Norway rat)
p38MAPK events	GTPase HRas GTPase KRas GTPase NRas MAP kinase-activated protein kinase 3 MAPK activated protein kinase 2 Mapk11 protein Mitogen-activated protein kinase 14 Ral guanine nucleotide dissociation stimulator	D4A3U7 P08644 P20171 P70618 Q03386 Q04970 Q66H84 Q80ZF4	Csbp1 Csbp2 Hras Hras1 Kras Kras2 Mapk11 Mapk14 Mapkapk2 Mapkapk3 Nras Ralgds	Rattus norvegicus (Norway rat)

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