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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
neurodegenerative disease
Summary
- Synonym
-
- degenerative disease
- Definition
- A central nervous system disease that results in the progressive deterioration of function or structure of neurons.
- Super Class
- central nervous system disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 50 | ACO2 | aconitase 2 | |
| 334 | APLP2 | amyloid beta precursor like protein 2 | |
| 387 | RHOA | ras homolog family member A | |
| 388 | RHOB | ras homolog family member B | |
| 389 | RHOC | ras homolog family member C | |
| 847 | CAT | catalase | |
| 1778 | DYNC1H1 | dynein cytoplasmic 1 heavy chain 1 | |
| 1855 | DVL1 | dishevelled segment polarity protein 1 | |
| 1857 | DVL3 | dishevelled segment polarity protein 3 | |
| 2011 | MARK2 | microtubule affinity regulating kinase 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 19170 | Psmb1 | proteasome (prosome, macropain) subunit, beta type 1 | |
| 19179 | Psmc1 | protease (prosome, macropain) 26S subunit, ATPase 1 | |
| 19206 | Ptch1 | patched 1 | |
| 19207 | Ptch2 | patched 2 | |
| 20276 | Scnn1a | sodium channel, nonvoltage-gated 1 alpha | |
| 20277 | Scnn1b | sodium channel, nonvoltage-gated 1 beta | |
| 20278 | Scnn1g | sodium channel, nonvoltage-gated 1 gamma | |
| 20510 | Slc1a1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | |
| 20511 | Slc1a2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 | |
| 20512 | Slc1a3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 84487 | Slc17a6 | solute carrier family 17 member 6 | |
| 94198 | Psmb1 | proteasome 20S subunit beta 1 | |
| 157074 | Sdha | succinate dehydrogenase complex flavoprotein subunit A | |
| 171086 | Trak2 | trafficking kinesin protein 2 | |
| 266767 | Slc17a8 | solute carrier family 17 member 8 | |
| 287545 | Sarm1 | sterile alpha and TIR motif containing 1 | |
| 296851 | Pon2 | paraoxonase 2 | |
| 298521 | Grik3 | glutamate ionotropic receptor kainate type subunit 3 | |
| 300733 | Tspan3 | tetraspanin 3 | |
| 312086 | Pon3 | paraoxonase 3 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 192309 | tpi1a | triosephosphate isomerase 1a | |
| 403143 | sarm1 | sterile alpha and TIR motif containing 1 | |
| 406411 | rhoaa | ras homolog gene family, member Aa | |
| 406659 | rhoac | ras homolog gene family, member Ac | |
| 407667 | asic4b | acid-sensing (proton-gated) ion channel family member 4b | |
| 407668 | asic4a | acid-sensing (proton-gated) ion channel family member 4a | |
| 407669 | asic2 | acid-sensing (proton-gated) ion channel 2 | |
| 407670 | asic1c | acid-sensing (proton-gated) ion channel 1c | |
| 407672 | asic1b | acid-sensing (proton-gated) ion channel 1b | |
| 436718 | rhocb | ras homolog family member Cb |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 448598 | pon2 | paraoxonase 2 | Xenopus tropicalis (tropical clawed frog) | |
| 780064 | slc17a7 | solute carrier family 17 (vesicular glutamate transporter), member 7 | Xenopus tropicalis (tropical clawed frog) | |
| 100038162 | tpi1 | triosephosphate isomerase 1 | Xenopus tropicalis (tropical clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 173064 | ced-1 | Cell death abnormality protein 1 | |
| 173631 | ptc-3 | Protein patched homolog 3 | |
| 174274 | ptc-1 | Protein patched homolog 1;SSD domain-containing protein | |
| 175502 | tir-1 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;NAD(+) hydrolase tir-1;Sterile alpha and TIR motif-containing protein 1 | |
| 176204 | glr-1 | Glutamate receptor 1 | |
| 176291 | eat-4 | Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4 | |
| 176441 | vglu-2 | Major facilitator superfamily (MFS) profile domain-containing protein | |
| 176442 | vglu-3 | putative vesicular glutamate transporter vglu-3 | |
| 177882 | glt-3 | Putative sodium-dependent excitatory amino acid transporter glt-3 | |
| 180783 | apl-1 | Amyloid-beta-like protein |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 851013 | ACO1 | aconitate hydratase ACO1 | |
| 851620 | TPI1 | triose-phosphate isomerase TPI1 | |
| 853173 | MTM1 | Mtm1p | |
| 853770 | BUD2 | GTPase-activating protein BUD2 | |
| 853792 | OSI1 | Osi1p | |
| 854943 | NTE1 | lysophospholipase | |
| 855392 | FIG4 | phosphatidylinositol-3,5-bisphosphate 5-phosphatase | |
| 855897 | HRR25 | serine/threonine protein kinase HRR25 | |
| 856294 | RHO1 | Rho family GTPase RHO1 | |
| 856422 | RPN1 | proteasome regulatory particle base subunit RPN1 |
