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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
acute myeloid leukemia
Summary
- Synonym
-
- AML - acute Myeloid Leukemia
- Leukemia, Myelocytic, acute
- acute myeloblastic leukaemia
- acute myeloblastic leukemia
- acute myelogenous leukaemia
- acute myelogenous leukemia
- acute myeloid leukaemia
- Definition
- A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.
- Super Class
- myeloid leukemia
External Links
- Disease Ontology
- DOID:9119
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- GARD
- MGI genotype (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 1387 | CREBBP | CREB binding protein | |
| 1437 | CSF2 | colony stimulating factor 2 | |
| 1440 | CSF3 | colony stimulating factor 3 | |
| 1441 | CSF3R | colony stimulating factor 3 receptor | |
| 1493 | CTLA4 | cytotoxic T-lymphocyte associated protein 4 | |
| 1543 | CYP1A1 | cytochrome P450 family 1 subfamily A member 1 | |
| 1555 | CYP2B6 | cytochrome P450 family 2 subfamily B member 6 | |
| 1786 | DNMT1 | DNA methyltransferase 1 | |
| 2146 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | |
| 2152 | F3 | coagulation factor III, tissue factor |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 214133 | Tet2 | tet methylcytosine dioxygenase 2 | |
| 218952 | Fermt2 | fermitin family member 2 | |
| 227720 | Nup214 | nucleoporin 214 | |
| 228790 | Asxl1 | ASXL transcriptional regulator 1 | |
| 233489 | Picalm | phosphatidylinositol binding clathrin assembly protein | |
| 269951 | Idh2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | |
| 269966 | Nup98 | nucleoporin 98 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24296 | Cyp1a1 | cytochrome P450, family 1, subfamily a, polypeptide 1 | |
| 24479 | Idh1 | isocitrate dehydrogenase (NADP(+)) 1 | |
| 24493 | Il1a | interleukin 1 alpha | |
| 24600 | Nos3 | nitric oxide synthase 3 | |
| 24770 | Ccl2 | C-C motif chemokine ligand 2 | |
| 24787 | Sod2 | superoxide dismutase 2 | |
| 24842 | Tp53 | tumor protein p53 | |
| 25325 | Il10 | interleukin 10 | |
| 29302 | Itgb3 | integrin subunit beta 3 | |
| 50662 | Runx1 | RUNX family transcription factor 1 |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 373579 | kit.L | KIT proto-oncogene receptor tyrosine kinase L homeolog | Xenopus laevis (African clawed frog) | |
| 380373 | cxcr4.S | C-X-C motif chemokine receptor 4 S homeolog | Xenopus laevis (African clawed frog) | |
| 397782 | fgfr1.S | fibroblast growth factor receptor 1 S homeolog | Xenopus laevis (African clawed frog) | |
| 399444 | fgfr1.L | fibroblast growth factor receptor 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 548648 | fgfr1 | fibroblast growth factor receptor 1 | Xenopus tropicalis (tropical clawed frog) | |
| 100038176 | cxcr4 | C-X-C motif chemokine receptor 4 | Xenopus tropicalis (tropical clawed frog) | |
| 100192360 | cxcr4.L | C-X-C motif chemokine receptor 4 L homeolog | Xenopus laevis (African clawed frog) | |
| 100337618 | cdh1.S | cadherin 1, type 1 S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 172813 | npp-14 | Nuclear pore complex protein 14 | |
| 175182 | ver-1 | Protein ver-1 | |
| 175504 | pat-3 | Integrin beta pat-3 | |
| 176240 | pat-2 | Integrin alpha pat-2 | |
| 180408 | mrp-2 | Multidrug resistance-associated protein 1 | |
| 180409 | mrp-1 | Multidrug resistance-associated protein 1 | |
| 180628 | cht-1 | putative endochitinase | |
| 181178 | gpx-5 | Glutathione peroxidase | |
| 182513 | gpx-3 | Glutathione peroxidase 3 | |
| 186632 | ver-4 | Tyrosine-protein kinase receptor ver-4 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850369 | ADP1 | putative ATP-dependent permease ADP1 | |
| 850871 | IDP2 | isocitrate dehydrogenase (NADP(+)) IDP2 | |
| 851493 | IDP1 | isocitrate dehydrogenase (NADP(+)) IDP1 | |
| 851977 | CTS2 | putative chitinase | |
| 852495 | PGI1 | glucose-6-phosphate isomerase | |
| 852788 | NUP145 | nucleocytoplasmic transporter NUP145 | |
| 853590 | VPS70 | putative zinc metalloprotease | |
| 854430 | TRE2 | putative zinc metalloprotease | |
| 855723 | IDP3 | isocitrate dehydrogenase (NADP(+)) IDP3 | |
| 855927 | TRE1 | Tre1p |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000006 | Autosomal dominant inheritance |
| HP:0001442 | Typified by somatic mosaicism |
| HP:0004808 | Acute myeloid leukemia |
