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Standards Ontologies Notations
acute myeloid leukemia

Summary
Synonym
  • AML - acute Myeloid Leukemia
  • Leukemia, Myelocytic, acute
  • acute myeloblastic leukaemia
  • acute myeloblastic leukemia
  • acute myelogenous leukaemia
  • acute myelogenous leukemia
  • acute myeloid leukaemia
Definition
A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.
Super Class
myeloid leukemia
Disease Ontology
DOID:9119
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 61 - 70 of 77 in total
Gene ID Gene Symbol Description Source
8021 NUP214 nucleoporin 214
8028 MLLT10 MLLT10 histone lysine methyltransferase DOT1L cofactor
8233 ZRSR2 zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2
8301 PICALM phosphatidylinositol binding clathrin assembly protein
8714 ABCC3 ATP binding cassette subfamily C member 3
8772 FADD Fas associated via death domain
9429 ABCG2 ATP binding cassette subfamily G member 2 (JR blood group)
10499 NCOA2 nuclear receptor coactivator 2
23236 PLCB1 phospholipase C beta 1
23305 ACSL6 acyl-CoA synthetase long chain family member 6
Displaying entries 41 - 50 of 57 in total
Gene ID Gene Symbol Description Source
21950 Tnfsf9 tumor necrosis factor (ligand) superfamily, member 9
21973 Top2a topoisomerase (DNA) II alpha
21974 Top2b topoisomerase (DNA) II beta
22059 Trp53 transformation related protein 53
22339 Vegfa vascular endothelial growth factor A
26357 Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group)
50702 Cfhr1 complement factor H-related 1
50765 Tfr2 transferrin receptor 2
76408 Abcc3 ATP-binding cassette, sub-family C member 3
210126 Lpp LIM domain containing preferred translocation partner in lipoma
Displaying entries 1 - 10 of 25 in total
Gene ID Gene Symbol Description Source
24296 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
24479 Idh1 isocitrate dehydrogenase (NADP(+)) 1
24493 Il1a interleukin 1 alpha
24600 Nos3 nitric oxide synthase 3
24770 Ccl2 C-C motif chemokine ligand 2
24787 Sod2 superoxide dismutase 2
24842 Tp53 tumor protein p53
25325 Il10 interleukin 10
29302 Itgb3 integrin subunit beta 3
50662 Runx1 RUNX family transcription factor 1
Displaying entries 11 - 15 of 15 in total
Gene ID Gene Symbol Description Source
41166 Calr Calreticulin
41737 trx trithorax
42160 htl heartless
44885 mys myospheroid
46091 Nup214 Nucleoporin 214kD
Displaying all 4 entries
Gene ID Gene Symbol Description Source
30256 kita KIT proto-oncogene, receptor tyrosine kinase a
30682 vegfaa vascular endothelial growth factor Aa
30705 fgfr1a fibroblast growth factor receptor 1a
114424 cdh1 cadherin 1, type 1, E-cadherin (epithelial)
Displaying all 8 entries
Gene ID Gene Symbol Description Source Organism
373579 kit.L KIT proto-oncogene receptor tyrosine kinase L homeolog Xenopus laevis (African clawed frog)
380373 cxcr4.S C-X-C motif chemokine receptor 4 S homeolog Xenopus laevis (African clawed frog)
397782 fgfr1.S fibroblast growth factor receptor 1 S homeolog Xenopus laevis (African clawed frog)
399444 fgfr1.L fibroblast growth factor receptor 1 L homeolog Xenopus laevis (African clawed frog)
548648 fgfr1 fibroblast growth factor receptor 1 Xenopus tropicalis (tropical clawed frog)
100038176 cxcr4 C-X-C motif chemokine receptor 4 Xenopus tropicalis (tropical clawed frog)
100192360 cxcr4.L C-X-C motif chemokine receptor 4 L homeolog Xenopus laevis (African clawed frog)
100337618 cdh1.S cadherin 1, type 1 S homeolog Xenopus laevis (African clawed frog)
Displaying all 10 entries
Gene ID Gene Symbol Description Source
172813 npp-14 Nuclear pore complex protein 14
175182 ver-1 Protein ver-1
175504 pat-3 Integrin beta pat-3
176240 pat-2 Integrin alpha pat-2
180408 mrp-2 Multidrug resistance-associated protein 1
180409 mrp-1 Multidrug resistance-associated protein 1
180628 cht-1 putative endochitinase
181178 gpx-5 Glutathione peroxidase
182513 gpx-3 Glutathione peroxidase 3
186632 ver-4 Tyrosine-protein kinase receptor ver-4
Displaying entries 1 - 10 of 11 in total
Gene ID Gene Symbol Description Source
850369 ADP1 putative ATP-dependent permease ADP1
850871 IDP2 isocitrate dehydrogenase (NADP(+)) IDP2
851493 IDP1 isocitrate dehydrogenase (NADP(+)) IDP1
851977 CTS2 putative chitinase
852495 PGI1 glucose-6-phosphate isomerase
852788 NUP145 nucleocytoplasmic transporter NUP145
853590 VPS70 putative zinc metalloprotease
854430 TRE2 putative zinc metalloprotease
855723 IDP3 isocitrate dehydrogenase (NADP(+)) IDP3
855927 TRE1 Tre1p
The Human Phenotype Ontology
Displaying all 3 entries
HPO ID HPO Term
HP:0000006 Autosomal dominant inheritance
HP:0001442 Typified by somatic mosaicism
HP:0004808 Acute myeloid leukemia
Displaying 1 entry
Gene ID Gene Symbol Description
3845 KRAS KRAS proto-oncogene, GTPase
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024