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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
colorectal cancer
Summary
- Definition
- A large intestine cancer that is located_in the colon and/or located_in the rectum.
- Super Class
- large intestine cancer
External Links
- Disease Ontology
- DOID:9256
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 3192 | HNRNPU | heterogeneous nuclear ribonucleoprotein U | |
| 3265 | HRAS | HRas proto-oncogene, GTPase | |
| 3312 | HSPA8 | heat shock protein family A (Hsp70) member 8 | |
| 3569 | IL6 | interleukin 6 | |
| 3716 | JAK1 | Janus kinase 1 | |
| 3791 | KDR | kinase insert domain receptor | |
| 3845 | KRAS | KRAS proto-oncogene, GTPase | |
| 3897 | L1CAM | L1 cell adhesion molecule | |
| 3976 | LIF | LIF interleukin 6 family cytokine | |
| 4015 | LOX | lysyl oxidase |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11350 | Abl1 | c-abl oncogene 1, non-receptor tyrosine kinase | |
| 11487 | Adam10 | a disintegrin and metallopeptidase domain 10 | |
| 11651 | Akt1 | thymoma viral proto-oncogene 1 | |
| 11652 | Akt2 | thymoma viral proto-oncogene 2 | |
| 11814 | Apoc3 | apolipoprotein C-III | |
| 12007 | Azgp1 | alpha-2-glycoprotein 1, zinc | |
| 12028 | Bax | BCL2-associated X protein | |
| 12229 | Btk | Bruton agammaglobulinemia tyrosine kinase | |
| 12235 | Bub1 | BUB1, mitotic checkpoint serine/threonine kinase | |
| 12305 | Ddr1 | discoidin domain receptor family, member 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 25283 | Gclc | glutamate-cysteine ligase, catalytic subunit | |
| 25311 | Dcc | DCC netrin 1 receptor | |
| 25496 | Notch1 | notch receptor 1 | |
| 25513 | Pik3r1 | phosphoinositide-3-kinase regulatory subunit 1 | |
| 25589 | Kdr | kinase insert domain receptor | |
| 25717 | Tgfb3 | transforming growth factor, beta 3 | |
| 29199 | Hfe | homeostatic iron regulator | |
| 29499 | Shh | sonic hedgehog signaling molecule | |
| 29591 | Tgfbr1 | transforming growth factor, beta receptor 1 | |
| 29613 | Ntrk3 | neurotrophic receptor tyrosine kinase 3 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31293 | N | Notch | |
| 31792 | Nrg | Neuroglian | |
| 32556 | Stim | Stromal interaction molecule | |
| 33196 | smo | smoothened | |
| 33496 | lilli | lilliputian | |
| 34091 | Spn28Dc | Serpin 28Dc | |
| 35560 | Bap170 | Brahma associated protein 170kD | |
| 37455 | Egfr | Epidermal growth factor receptor | |
| 39392 | Est-6 | Esterase 6 | |
| 39393 | Est-P | Esterase P |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30225 | smo | smoothened, frizzled class receptor | |
| 30682 | vegfaa | vascular endothelial growth factor Aa | |
| 30718 | notch1a | notch receptor 1a | |
| 406411 | rhoaa | ras homolog gene family, member Aa | |
| 406659 | rhoac | ras homolog gene family, member Ac | |
| 554230 | kdr | kinase insert domain receptor (a type III receptor tyrosine kinase) | |
| 559736 | galnt12 | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 | |
| 100006041 | rhoab | ras homolog gene family, member Ab |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 100038176 | cxcr4 | C-X-C motif chemokine receptor 4 | Xenopus tropicalis (tropical clawed frog) | |
| 100127346 | grin2a.L | glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog | Xenopus laevis (African clawed frog) | |
| 100192360 | cxcr4.L | C-X-C motif chemokine receptor 4 L homeolog | Xenopus laevis (African clawed frog) | |
| 100485011 | galnt12 | polypeptide N-acetylgalactosaminyltransferase 12 | Xenopus tropicalis (tropical clawed frog) | |
| 100491274 | rnf43 | ring finger protein 43 | Xenopus tropicalis (tropical clawed frog) | |
| 108719043 | galnt12.L | polypeptide N-acetylgalactosaminyltransferase 12 L homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 172233 | unc-40 | Netrin receptor unc-40 | |
| 172689 | sup-17 | Disintegrin and metalloproteinase domain-containing protein 10 homolog | |
| 174044 | sma-6 | Serine/threonine-protein kinase receptor sma-6 | |
| 174462 | let-23 | Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase | |
| 175182 | ver-1 | Protein ver-1 | |
| 175201 | stim-1 | Stromal interaction molecule 1 | |
| 175590 | cdh-4 | Cadherin-4 | |
| 176282 | lin-12 | lin-12/Notch intracellular domain | |
| 176286 | glp-1 | glp-1/Notch intracellular domain | |
| 176575 | plr-1 | putative E3 ubiquitin-protein ligase plr-1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850438 | ERS1 | cystinosin-like protein ERS1 | |
| 850614 | HXK1 | hexokinase 1 | |
| 851543 | OSH2 | oxysterol-binding protein related protein OSH2 | |
| 851670 | GIS1 | histone demethylase GIS1 | |
| 852410 | CYC8 | transcription regulator CYC8 | |
| 852546 | GPX2 | glutathione peroxidase GPX2 | |
| 853313 | PBS2 | mitogen-activated protein kinase kinase PBS2 | |
| 853361 | ALY2 | Aly2p | |
| 853770 | BUD2 | GTPase-activating protein BUD2 | |
| 853842 | GPX1 | glutathione peroxidase GPX1 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000006 | Autosomal dominant inheritance |
| HP:0006716 | Hereditary nonpolyposis colorectal carcinoma |
| HP:0002891 | Uterine leiomyosarcoma |
| HP:0006753 | Neoplasm of the stomach |
| HP:0001442 | Typified by somatic mosaicism |
| HP:0006740 | Transitional cell carcinoma of the bladder |
| HP:0005584 | Renal cell carcinoma |
