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Standards Ontologies Notations
Guidelines
MIRAGE
type 2 diabetes mellitus

Summary
Synonym
  • NIDDM
  • insulin resistance
  • non-insulin-dependent diabetes mellitus
  • type 2 diabetes
  • type II diabetes mellitus
Definition
A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Super Class
diabetes mellitus
Disease Ontology
DOID:9352
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 121 - 129 of 129 in total
Gene ID Gene Symbol Description Source
51206 GP6 glycoprotein VI platelet
51738 GHRL ghrelin and obestatin prepropeptide
54901 CDKAL1 CDKAL1 threonylcarbamoyladenosine tRNA methylthiotransferase
55937 APOM apolipoprotein M
64805 P2RY12 purinergic receptor P2Y12
79068 FTO FTO alpha-ketoglutarate dependent dioxygenase
80339 PNPLA3 patatin like domain 3, 1-acylglycerol-3-phosphate O-acyltransferase
116519 APOA5 apolipoprotein A5
253559 CADM2 cell adhesion molecule 2
Displaying entries 11 - 19 of 19 in total
Gene ID Gene Symbol Description Source
20614 Snap25 synaptosomal-associated protein 25
50518 a nonagouti
53412 Ppp1r3c protein phosphatase 1, regulatory subunit 3C
68916 Cdkal1 CDK5 regulatory subunit associated protein 1-like 1
103988 Gck glucokinase
140491 Ppp1r3a protein phosphatase 1, regulatory subunit 3A
228355 Madd MAP-kinase activating death domain
266690 Cyb5r4 cytochrome b5 reductase 4
384783 Irs2 insulin receptor substrate 2
Displaying entries 1 - 10 of 21 in total
Gene ID Gene Symbol Description Source
24185 Akt1 AKT serine/threonine kinase 1
24385 Gck glucokinase
24536 Lepr leptin receptor
24617 Serpine1 serpin family E member 1
24835 Tnf tumor necrosis factor
24889 Cckar cholecystokinin A receptor
25024 Gipr gastric inhibitory polypeptide receptor
25204 Pcsk1 proprotein convertase subtilisin/kexin type 1
25467 Irs1 insulin receptor substrate 1
25608 Lep leptin
Displaying all 2 entries
Gene ID Gene Symbol Description Source
33496 lilli lilliputian
42549 InR Insulin-like receptor
Displaying all 3 entries
Gene ID Gene Symbol Description Source
176000 ogt-1 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase;protein O-GlcNAc transferase
177850 gon-1 A disintegrin and metalloproteinase with thrombospondin motifs gon-1;Peptidase M12B domain-containing protein
266823 parp-1 Poly [ADP-ribose] polymerase;Poly [ADP-ribose] polymerase 1
Displaying 1 entry
Gene ID Gene Symbol Description Source
856386 LAG1 sphingosine N-acyltransferase LAG1
Related Glycoprotein
Displaying 1 entry
UniProt ID Protein Name Source
P38703 Ceramide synthase LAG1
The Human Phenotype Ontology
Displaying all 4 entries
HPO ID HPO Term
HP:0000855 Insulin resistance
HP:0005978 Type II diabetes mellitus
HP:0000006 Autosomal dominant inheritance
HP:0003584 Late onset
Displaying all 6 entries
Gene ID Gene Symbol Description
2645 GCK glucokinase
2820 GPD2 glycerol-3-phosphate dehydrogenase 2
3990 LIPC lipase C, hepatic type
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
5506 PPP1R3A protein phosphatase 1 regulatory subunit 3A
6514 SLC2A2 solute carrier family 2 member 2
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025