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Standards Ontologies Notations
type 2 diabetes mellitus

Summary
Synonym
  • NIDDM
  • insulin resistance
  • non-insulin-dependent diabetes mellitus
  • type 2 diabetes
  • type II diabetes mellitus
Definition
A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Super Class
diabetes mellitus
Disease Ontology
DOID:9352
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 161 - 170 of 325 in total
Gene ID Gene Symbol Description Source
4089 SMAD4 SMAD family member 4
4282 MIF macrophage migration inhibitory factor
4288 MKI67 marker of proliferation Ki-67
4312 MMP1 matrix metallopeptidase 1
4313 MMP2 matrix metallopeptidase 2
4314 MMP3 matrix metallopeptidase 3
4318 MMP9 matrix metallopeptidase 9
4502 MT2A metallothionein 2A
4543 MTNR1A melatonin receptor 1A
4544 MTNR1B melatonin receptor 1B
Displaying entries 191 - 200 of 249 in total
Gene ID Gene Symbol Description Source
24053 Sgcg sarcoglycan, gamma (dystrophin-associated glycoprotein)
26357 Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group)
26362 Axl AXL receptor tyrosine kinase
26383 Fto FTO alpha-ketoglutarate dependent dioxygenase
27226 Pla2g7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
30930 Vps26a VPS26 retromer complex component A
50518 a nonagouti
53322 Nucb2 nucleobindin 2
53412 Ppp1r3c protein phosphatase 1, regulatory subunit 3C
56373 Cpb2 carboxypeptidase B2
Displaying entries 91 - 100 of 166 in total
Gene ID Gene Symbol Description Source
25712 Ifng interferon gamma
25718 Igf1r insulin-like growth factor 1 receptor
25757 Cpt1a carnitine palmitoyltransferase 1A
26295 Ogt O-linked N-acetylglucosamine (GlcNAc) transferase
29139 Dcn decorin
29199 Hfe homeostatic iron regulator
29260 Tlr4 toll-like receptor 4
29340 Prkce protein kinase C, epsilon
29414 Akt3 AKT serine/threonine kinase 3
29473 Aoc3 amine oxidase, copper containing 3
Displaying entries 1 - 10 of 80 in total
Gene ID Gene Symbol Description Source
31234 Pdfr Pigment-dispersing factor receptor
31248 sgg shaggy
31271 w white
31806 Ogg1 8-oxoguanine DNA glycosylase
31926 Idgf4 Imaginal disc growth factor 4
32442 Rab3-GEF Rab3 GDP-GTP exchange factor
32974 Zw Zwischenferment
33007 Dop2R Dopamine 2-like receptor
33496 lilli lilliputian
34091 Spn28Dc Serpin 28Dc
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
30173 nog3 noggin 3
30174 nog1 noggin 1
30262 ins preproinsulin
30667 mtnr1aa melatonin receptor 1A a
30668 mtnr1bb melatonin receptor 1Bb
30682 vegfaa vascular endothelial growth factor Aa
266751 adra2b adrenoceptor alpha 2B
321664 aldob aldolase b, fructose-bisphosphate
337685 ogt.1 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
393807 ppp1r3cb protein phosphatase 1, regulatory subunit 3Cb
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source Organism
373759 cnr1.S cannabinoid receptor 1 (brain) S homeolog Xenopus laevis (African clawed frog)
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
379783 akt2.L v-akt murine thymoma viral oncogene homolog 2 L homeolog Xenopus laevis (African clawed frog)
380341 pon2.L paraoxonase 2 L homeolog Xenopus laevis (African clawed frog)
394283 sdc2.S syndecan 2 S homeolog Xenopus laevis (African clawed frog)
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
398006 insr.L insulin receptor L homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 69 in total
Gene ID Gene Symbol Description Source
171619 C53D5.5 Gamma-glutamyltranspeptidase 1
171782 abt-2 ABC transporter domain-containing protein
171905 ace-2 Carboxylic ester hydrolase
171999 poml-2 Arylesterase
172085 ugt-26 UDP-glucuronosyltransferase
172509 gpdh-3 putative glycerol-3-phosphate dehydrogenase, mitochondrial
173297 F49B2.6 Aminopeptidase
174685 ptp-3 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like;protein-tyrosine-phosphatase
175076 ace-3 Carboxylic ester hydrolase
175182 ver-1 Protein ver-1
Displaying entries 1 - 10 of 32 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850369 ADP1 putative ATP-dependent permease ADP1
850391 NPP1 nucleotide diphosphatase/phosphodiesterase NPP1
850614 HXK1 hexokinase 1
850645 BPT1 ATP-binding cassette bilirubin transporter BPT1
850678 YBT1 bile acid-transporting ATPase YBT1
850886 ATG26 sterol 3-beta-glucosyltransferase
850979 PIG1 protein phosphatase regulator PIG1
851006 ECM38 gamma-glutamyltransferase
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
The Human Phenotype Ontology
Displaying all 4 entries
HPO ID HPO Term
HP:0000855 Insulin resistance
HP:0005978 Type II diabetes mellitus
HP:0000006 Autosomal dominant inheritance
HP:0003584 Late onset
Displaying all 6 entries
Gene ID Gene Symbol Description
2645 GCK glucokinase
2820 GPD2 glycerol-3-phosphate dehydrogenase 2
3990 LIPC lipase C, hepatic type
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
5506 PPP1R3A protein phosphatase 1 regulatory subunit 3A
6514 SLC2A2 solute carrier family 2 member 2
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024