Inhibition of TSC complex formation by PKB
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Activation of PKB
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- Akt2
- Nipk
- Pdk1
- Pdpk1
- Them4
- Trib3
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mTORC1-mediated signalling
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- Akt1s1
- ENSRNOG00000066475
- Eef2k
- Eif4e
- Eif4ebp1
- Eif4g1
- Fkbp1
- Fkbp1a
- Frap1
- Gbl
- Lamtor1
- Lamtor3
- Lamtor4
- Lamtor5
- Lst8
- Map2k1ip1
- Mlst8
- Mtor
- Raft1
- Rheb
- Rps6
- Rps6kb1
- Rptor
- RragB
- Rraga
- Rragc
- Rragc_predicted
- Rragd
- Slc38a9
- Ywhab
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HSF1-dependent transactivation
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- Akt1s1
- Camk2a
- Camk2b
- Camk2d
- Camk2g
- Cryab
- Cryac
- Dnajb1
- Frap1
- Gbl
- Hsbp1
- Hsc70
- Hsc73
- Hsf1
- Hsp22
- Hsp70-1
- Hsp70-2
- Hsp70-3
- Hsp84
- Hsp86
- Hsp90aa1
- Hsp90ab1
- Hspa1
- Hspa1a
- Hspa1b
- Hspa1l
- Hspa2
- Hspa8
- Hspb8
- Hspc3
- Hspca
- Hspcb
- Lst8
- Mlst8
- Mtor
- Raft1
- Rptor
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Negative regulation of NOTCH4 signaling
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KSRP (KHSRP) binds and destabilizes mRNA
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- Akt1
- Dcp2
- Dis3
- Exosc1
- Exosc2
- Exosc3
- Exosc4
- Exosc5
- Exosc6
- Exosc7
- Exosc8
- Exosc9
- Fubp2
- Khsrp
- LOC103690064
- LOC679140
- Msfs1
- Parn
- Ywhaz
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Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
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- Akt1
- CaMIII
- Calm3
- Cam3
- Camc
- Gch
- Gch1
- Gchfr
- Gfrp
- Hsp86
- Hsp90aa1
- Hspca
- Nos3
- Prkg2
- Pts
- Spr
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Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
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- Akt1
- Brf1
- Cmg1
- Dcp1a
- Dcp2
- Dis3
- Exosc1
- Exosc2
- Exosc3
- Exosc4
- Exosc5
- Exosc6
- Exosc7
- Exosc8
- Exosc9
- LOC103690064
- LOC679140
- Mapkapk2
- Tis11b
- Xrn1
- Ywhab
- Zfp36l1
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Extra-nuclear estrogen signaling
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- Akt1
- Areg
- Btc
- CaMIII
- Calm3
- Cam3
- Camc
- Cav
- Cav1
- Cav2
- Dtr
- Egf
- Egfr
- Erbeta
- Ereg
- Esr
- Esr1
- Esr2
- Estr
- Fak
- Fak1
- Gnai-1
- Gnai-2
- Gnai-3
- Gnai1
- Gnai2
- Gnai3
- Gnat-3
- Gnat3
- Hbegf
- Hegfl
- Hrmt1l2
- Hsp86
- Hsp90aa1
- Hspca
- Igf1r
- Mmp-7
- Mmp2
- Mmp3
- Mmp7
- Mmp9
- Nos3
- Nr3a1
- Nr3a2
- Pik3ca
- Pik3r1
- Pik3r2
- Pik3r3
- Prmt1
- Ptk2
- S1pr3
- Sdgf
- Serz
- Shc1
- Sphk1
- Src
- Strn
- Tgfa
- Zdhhc7
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PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1
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- Akt1
- Arap1
- Cbl
- Dok1
- LOC100360645
- Ptk6
- Rps27a
- Uba80
- Ubb
- Ubbl1
- Ubc
- Ubcep1
- Ubcl1
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eNOS activation
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- Akt1
- Apt1
- CaMIII
- Calm3
- Cam3
- Camc
- Cav
- Cav1
- Cygb
- Ddah
- Ddah1
- Hsp86
- Hsp90aa1
- Hspca
- Lypla1
- Nos3
- Spr
- Stap
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Integrin signaling
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- Akt1
- Apbb1ip
- Cgef2
- Csk
- Epac
- Epac1
- Epac2
- Fak
- Fak1
- Fga
- Fgb
- Fgg
- Fn1
- Itga2b
- Itgb3
- Krev1
- Pdk1
- Pdpk1
- Ptk2
- Ptpn1
- Rap1a
- Rap1b
- Rapgef3
- Rapgef4
- Rasgrp
- Rasgrp1
- Rasgrp2
- Shc1
- Src
- Syk
- Tln1
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Deactivation of the beta-catenin transactivating complex
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- Akt1
- Akt2
- Apc
- Api3
- Bars
- Birc4
- Btrc
- Catnb
- Cby
- Cby1
- Chd8
- Crm1
- Ctbp1
- Ctbp3
- Ctnnb1
- Ctnnbip1
- Esp2
- Esp3
- Grg4
- Hdac1
- LOC100360645
- Lef1
- Msfs1
- Pgea1
- Rps27a
- Sox-6
- Sox13
- Sox17
- Sox2
- Sox3
- Sox4
- Sox6
- Sox7
- Sox9
- Tcf7
- Tcf7l1
- Tcf7l2
- Tle1
- Tle2
- Tle3
- Tle4
- Uba80
- Ubb
- Ubbl1
- Ubc
- Ubcep1
- Ubcl1
- Xiap
- Xpo1
- Ywhaz
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Negative regulation of the PI3K/AKT network
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- Akt1
- Akt2
- Akt3
- Nipk
- Phlpp
- Phlpp1
- Plekhe1
- Pten
- Scop
- Them4
- Trib3
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AKT-mediated inactivation of FOXO1A
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- Akt1
- Akt2
- Akt3
- Foxo1
- Foxo1a
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Regulation of localization of FOXO transcription factors
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- Akt1
- Akt2
- Akt3
- Foxo1
- Foxo1a
- Foxo3
- Foxo4
- Foxo6
- Msfs1
- Sfn
- Ywhab
- Ywhag
- Ywhaq
- Ywhaz
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Downregulation of ERBB2:ERBB3 signaling
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- Akt1
- Akt2
- Akt3
- Erbb2
- Erbb3
- LOC100360645
- Ndf
- Neu
- Nrg1
- Nrg2
- Ntak
- Rnf41
- Rps27a
- Uba80
- Ubb
- Ubbl1
- Ubc
- Ubcep1
- Ubcl1
- Usp8
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AKT phosphorylates targets in the nucleus
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- Akt1
- Akt2
- Akt3
- Creb-1
- Creb1
- Foxo1
- Foxo1a
- Foxo3
- Foxo4
- Foxo6
- Hmr
- Ngfib
- Nr4a1
- Rps6kb2
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Estrogen-dependent nuclear events downstream of ESR-membrane signaling
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- Akt1
- Akt2
- Akt3
- Cdkn1b
- Creb-1
- Creb1
- Crm1
- Erk2
- Foxo3
- Kis
- Kist
- Mapk
- Mapk1
- Prkm1
- Uhmk1
- Xpo1
- p27Kip1
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CTLA4 inhibitory signaling
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- Akt1
- Akt2
- Akt3
- Cd80
- Cd86
- Ctla4
- Fyn
- LOC100909468
- Lck
- Lyn
- Ppp2ca
- Ppp2cb
- Ppp2r1a
- Ppp2r1b
- Ppp2r5a
- Ppp2r5b
- Ppp2r5c
- Ppp2r5d
- Ppp2r5e
- Ptpn11
- Src
- Yes1
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CD28 dependent PI3K/Akt signaling
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- Akt1
- Akt2
- Akt3
- Cd28
- Cd80
- Cd86
- Frap1
- Fyn
- Gbl
- Lck
- Lst8
- Map3k14
- Map3k8
- Mapkap1
- Mip1
- Mlst8
- Mtor
- Nipk
- Pdk1
- Pdpk1
- Pik3ca
- Pik3r1
- Pik3r2
- Pik3r3
- Protor1
- Prr5
- Raft1
- Rictor
- Sin1
- Them4
- Tpl2
- Trib3
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Cyclin E associated events during G1/S transition
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- Akt1
- Akt2
- Akt3
- Cables1
- Cak
- Cak1
- Ccne
- Ccne1
- Ccne2
- Ccnh
- Cdc25a
- Cdk2
- Cdk7
- Cdkn1a
- Cdkn1b
- Cdkn2
- Mnat1
- Mo15
- Rb-1
- Rb1
- Wee1
- p27Kip1
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Cyclin A:Cdk2-associated events at S phase entry
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- Akt1
- Akt2
- Akt3
- Cables1
- Cak
- Cak1
- Ccna1
- Ccna2
- Ccnh
- Cdc25a
- Cdc25b
- Cdk2
- Cdk7
- Cdkn1a
- Cdkn1b
- Cdkn2
- Fzr1
- Mnat1
- Mo15
- Rb-1
- Rb1
- Wee1
- p27Kip1
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VEGFR2 mediated vascular permeability
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- Akt1
- Akt2
- Akt3
- CaMIII
- Calm3
- Cam3
- Camc
- Catnb
- Cav
- Cav1
- Cdh5
- Ctnnb1
- Ctnnd1
- Frap1
- Gbl
- Hsp86
- Hsp90aa1
- Hspca
- Jup
- Lst8
- Mapkap1
- Mip1
- Mlst8
- Mtor
- Nipk
- Nos3
- Pak1
- Pak2
- Pak3
- Pdk1
- Pdpk1
- Pg
- Protor1
- Prr5
- Rac
- Rac1
- Raft1
- Rictor
- Sin1
- Them4
- Trib3
- Vav
- Vav1
- Vav2
- Vav3
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Regulation of TP53 Activity through Association with Co-factors
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- Akt1
- Akt2
- Akt3
- Brn-3
- Brn3
- Brn3a
- Brn3b
- Ket
- P53
- P63
- Phf20
- Pou4f1
- Pou4f2
- Ppp1r13b
- Ppp1r13l
- Tp53
- Tp53bp2
- Tp63
- Tp73
- Tp73l
- Trp63
- Zfp385a
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