SUMO is conjugated to E1 (UBA2:SAE1)
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- AOS1
- SAE1
- SAE2
- SMT3A
- SMT3B
- SMT3C
- SMT3H1
- SMT3H2
- SMT3H3
- SUA1
- SUMO1
- SUMO2
- SUMO3
- UBA2
- UBL1
- UBLE1A
- UBLE1B
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STING mediated induction of host immune responses
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- ABS
- C6orf150
- CGAS
- DDX41
- ERIS
- IFI16
- IFNGIP1
- MB21D1
- MITA
- RNF81
- RO52
- SSA1
- STING
- STING1
- TMEM173
- TRIM21
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STAT6-mediated induction of chemokines
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- ERIS
- MITA
- NAK
- STAT6
- STING
- STING1
- TBK1
- TMEM173
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STAT5 activation downstream of FLT3 ITD mutants
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- ASH
- BCL2L
- BCL2L1
- BCLX
- CAP20
- CD135
- CDKN1
- CDKN1A
- CIP1
- FLK2
- FLT3
- GAB2
- GRB2
- KIAA0571
- MDA6
- NOX4
- PIC1
- PIM1
- PTP2C
- PTPN11
- RENOX
- SDI1
- SHPTP2
- STAT5
- STAT5A
- STAT5B
- STK1
- WAF1
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STAT5 Activation
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- CD135
- FLK2
- FLT3
- FLT3LG
- GAB2
- KIAA0571
- PTP2C
- PTPN11
- SHPTP2
- STAT5
- STAT5A
- STAT5B
- STK1
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STAT3 nuclear events downstream of ALK signaling
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- AIM
- APRF
- B7H1
- BHLHE78
- BLIMP1
- CD274
- CXXC9
- DNMT
- DNMT1
- EP300
- HDAC1
- HDAC2
- HDAC3
- HIF1A
- IL2RG
- MOP1
- P300
- PASD8
- PDCD1L1
- PDCD1LG1
- PDL1
- PRDM1
- RPD3L1
- SIN3A
- STAT3
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SRP-dependent cotranslational protein targeting to membrane
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- BBC1
- CCG2
- D11S2243E
- D6S218E
- DDOST
- DXS648E
- EC45
- FAU
- FTE1
- KIAA0102
- KIAA0115
- LAMBR
- LAMR1
- MFTL
- MPS1
- NEDD6
- OST48
- QM
- RIG
- RPL1
- RPL10
- RPL10A
- RPL10L
- RPL11
- RPL12
- RPL13
- RPL13A
- RPL14
- RPL15
- RPL17
- RPL18
- RPL18A
- RPL19
- RPL21
- RPL22
- RPL22L1
- RPL23
- RPL23A
- RPL24
- RPL26
- RPL26L1
- RPL26P1
- RPL27
- RPL27A
- RPL28
- RPL29
- RPL3
- RPL30
- RPL31
- RPL32
- RPL34
- RPL35
- RPL35A
- RPL36
- RPL36A
- RPL36AL
- RPL37
- RPL37A
- RPL38
- RPL39
- RPL39L
- RPL39L1
- RPL3L
- RPL4
- RPL41
- RPL44
- RPL5
- RPL6
- RPL7
- RPL7A
- RPL8
- RPL9
- RPL9P7
- RPL9P8
- RPL9P9
- RPLP0
- RPLP1
- RPLP2
- RPN1
- RPN2
- RPP2
- RPS10
- RPS11
- RPS12
- RPS13
- RPS14
- RPS15
- RPS15A
- RPS16
- RPS17
- RPS17L
- RPS18
- RPS19
- RPS2
- RPS20
- RPS21
- RPS23
- RPS24
- RPS25
- RPS26
- RPS27
- RPS27A
- RPS27L
- RPS28
- RPS29
- RPS3
- RPS3A
- RPS4
- RPS4X
- RPS4Y
- RPS4Y1
- RPS4Y2
- RPS4Y2P
- RPS5
- RPS6
- RPS7
- RPS8
- RPS9
- RPSA
- RRP1
- SCAR
- SEC11A
- SEC11C
- SEC11L1
- SEC11L3
- SEC61A
- SEC61A1
- SEC61A2
- SEC61B
- SEC61G
- SPC12
- SPC18
- SPC21
- SPC22
- SPC25
- SPCS1
- SPCS2
- SPCS3
- SPCS4A
- SPCS4C
- SRP14
- SRP19
- SRP54
- SRP68
- SRP72
- SRP9
- SRPR
- SRPRA
- SRPRB
- SSR1
- SSR2
- SSR3
- SSR4
- SURF-3
- SURF3
- TRAM
- TRAM1
- TRAPA
- TRAPB
- TRAPD
- TRAPG
- TXREB1
- UBA52
- UBA80
- UBCEP1
- UBCEP2
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SOS-mediated signalling
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- HRAS
- HRAS1
- IRS1
- IRS2
- NRAS
- SOS1
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SMAD4 MH2 Domain Mutants in Cancer
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- DPC4
- MADH2
- MADH3
- MADH4
- MADR2
- SMAD2
- SMAD3
- SMAD4
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SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
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- BHLHE39
- CCNC
- CCNK
- CCNT1
- CCNT2
- CDC2L4
- CDK8
- CDK9
- CDKN2B
- COL1A2
- CPR4
- DP1
- DP2
- DPC4
- E2F4
- E2F5
- EP300
- ERK1
- ERK2
- FUR
- FURIN
- HDAC1
- JUNB
- MADH2
- MADH3
- MADH4
- MADH7
- MADH8
- MADR2
- MAPK1
- MAPK3
- MEN1
- MTS2
- MYC
- NSEP1
- P300
- PACE
- PAI1
- PCSK3
- PLANH1
- PRKM1
- PRKM2
- PRKM3
- RBL1
- RNF111
- RPD3L1
- RPS27A
- SCG2
- SERPINE1
- SMAD2
- SMAD3
- SMAD4
- SMAD7
- SP1
- TAK
- TAZ
- TFDP1
- TFDP2
- TGIF
- TGIF1
- TGIF2
- TSFP1
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- WWTR1
- YB1
- YBX1
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SMAD2/3 Phosphorylation Motif Mutants in Cancer
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- ALK5
- MADH2
- MADH3
- MADR2
- SKR4
- SMAD2
- SMAD3
- TGFB
- TGFB1
- TGFBR1
- TGFBR2
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SMAD2/3 MH2 Domain Mutants in Cancer
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- DPC4
- MADH2
- MADH3
- MADH4
- MADR2
- SMAD2
- SMAD3
- SMAD4
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SMAC, XIAP-regulated apoptotic response
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- API3
- BIRC4
- CASP3
- CASP7
- CPP32
- DIABLO
- IAP3
- MCH3
- SMAC
- XIAP
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SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
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- APAF1
- API3
- BIRC4
- CASP3
- CASP7
- CASP9
- CPP32
- CYC
- CYCS
- DIABLO
- IAP3
- KIAA0413
- MCH3
- MCH6
- SMAC
- XIAP
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SMAC (DIABLO) binds to IAPs
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- APAF1
- API3
- BIRC4
- CASP3
- CASP7
- CASP9
- CPP32
- CYC
- CYCS
- DIABLO
- IAP3
- KIAA0413
- MCH3
- MCH6
- SMAC
- XIAP
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SLIT2:ROBO1 increases RHOA activity
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- ARH12
- ARHA
- DUTT1
- MYO9B
- MYR5
- RHO12
- RHOA
- ROBO1
- SLIL3
- SLIT2
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SLBP independent Processing of Histone Pre-mRNAs
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- CBP20
- CBP80
- COD
- KIAA1141
- LSM10
- LSM11
- NCBP
- NCBP1
- NCBP2
- PBSCF
- PBSCG
- SNRPB
- SNRPB1
- SNRPD3
- SNRPE
- SNRPF
- SNRPG
- ZFP100
- ZNF473
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SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
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- CBP20
- CBP80
- COD
- HBP
- KIAA1141
- LSM10
- LSM11
- NCBP
- NCBP1
- NCBP2
- PBSCF
- PBSCG
- SLBP
- SNRPB
- SNRPB1
- SNRPD3
- SNRPE
- SNRPF
- SNRPG
- ZFP100
- ZNF473
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SIRT1 negatively regulates rRNA expression
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- GTF2D1
- H2AB1
- H2AC14
- H2AC18
- H2AC19
- H2AC20
- H2AC4
- H2AC6
- H2AC7
- H2AC8
- H2AFA
- H2AFB1
- H2AFE
- H2AFG
- H2AFJ
- H2AFL
- H2AFM
- H2AFO
- H2AFQ
- H2AFV
- H2AFX
- H2AJ
- H2AV
- H2AX
- H2AZ2
- H2BC1
- H2BC10
- H2BC11
- H2BC12
- H2BC12L
- H2BC13
- H2BC14
- H2BC15
- H2BC17
- H2BC21
- H2BC26
- H2BC3
- H2BC4
- H2BC5
- H2BC6
- H2BC7
- H2BC8
- H2BC9
- H2BFA
- H2BFB
- H2BFC
- H2BFD
- H2BFE
- H2BFF
- H2BFG
- H2BFH
- H2BFJ
- H2BFK
- H2BFL
- H2BFN
- H2BFQ
- H2BFR
- H2BFS
- H2BFT
- H2BS1
- H2BU1
- H3-3A
- H3-3B
- H3.3A
- H3.3B
- H3C1
- H3C10
- H3C11
- H3C12
- H3C13
- H3C14
- H3C15
- H3C2
- H3C3
- H3C4
- H3C6
- H3C7
- H3C8
- H3F2
- H3F3
- H3F3A
- H3F3B
- H3FA
- H3FB
- H3FC HIST1H3C
- H3FD
- H3FF
- H3FH
- H3FI
- H3FJ
- H3FK
- H3FL
- H3FM
- H4-16
- H4/A
- H4/B
- H4/C
- H4/D
- H4/E
- H4/G
- H4/H
- H4/I
- H4/J
- H4/K
- H4/M
- H4/N
- H4/O
- H4C1
- H4C11
- H4C12
- H4C13
- H4C14
- H4C15
- H4C16
- H4C2
- H4C3
- H4C4
- H4C5
- H4C6
- H4C8
- H4C9
- H4F2
- H4FA
- H4FB
- H4FC
- H4FD
- H4FE
- H4FG
- H4FH
- H4FI
- H4FJ
- H4FK
- H4FM
- H4FN
- H4FO
- HIRIP1
- HIRIP2
- HIST1H2AB
- HIST1H2AC
- HIST1H2AD
- HIST1H2AE
- HIST1H2AJ
- HIST1H2BA
- HIST1H2BB
- HIST1H2BC
- HIST1H2BD
- HIST1H2BE
- HIST1H2BF
- HIST1H2BG
- HIST1H2BH
- HIST1H2BI
- HIST1H2BJ
- HIST1H2BK
- HIST1H2BL
- HIST1H2BM
- HIST1H2BN
- HIST1H2BO
- HIST1H3A
- HIST1H3B
- HIST1H3D
- HIST1H3E
- HIST1H3F
- HIST1H3G
- HIST1H3H
- HIST1H3I
- HIST1H3J
- HIST1H4A
- HIST1H4B
- HIST1H4C
- HIST1H4D
- HIST1H4E
- HIST1H4F
- HIST1H4H
- HIST1H4I
- HIST1H4J
- HIST1H4K
- HIST1H4L
- HIST2H2AA
- HIST2H2AA3
- HIST2H2AA4
- HIST2H2AC
- HIST2H2BE
- HIST2H3A
- HIST2H3C
- HIST2H3D
- HIST2H4
- HIST2H4A
- HIST2H4B
- HIST3H2BB
- HIST4H4
- JOSD3
- KIAA0409
- KMT1A
- NML
- RRP8
- SIR2L1
- SIRT1
- SUV39H
- SUV39H1
- TAF1A
- TAF1B
- TAF1C
- TAF1D
- TBP
- TF2D
- TFIID
- TSH2B
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SHOC2 M1731 mutant abolishes MRAS complex function
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- ARAF
- ARAF1
- BRAF
- BRAF1
- KIAA0862
- MRAS
- PKS
- PKS2
- PPP1CB
- PPP1CC
- RAF
- RAF1
- RAFB1
- RRAS3
- SHOC2
- YWHAB
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SHC1 events in ERBB4 signaling
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- BTC
- DTR
- DTS
- EREG
- GGF
- HBEGF
- HEGFL
- HGL
- HRAS
- HRAS1
- HRGA
- NDF
- NRAS
- NRG1
- NRG2
- NRG3
- NRG4
- NTAK
- SHC
- SHC1
- SHCA
- SMDF
- SOS1
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SHC1 events in ERBB2 signaling
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- BTC
- DTR
- DTS
- EGF
- EGFR
- ERBB
- ERBB1
- ERBB2
- EREG
- GGF
- HBEGF
- HEGFL
- HER1
- HER2
- HGL
- HRAS
- HRAS1
- HRGA
- MLN19
- NDF
- NEU
- NGL
- NRAS
- NRG1
- NRG2
- NRG3
- NRG4
- NTAK
- PKCA
- PKCD
- PKCE
- PRKACA
- PRKCA
- PRKCD
- PRKCE
- PTPN12
- SHC
- SHC1
- SHCA
- SMDF
- SOS1
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SHC1 events in EGFR signaling
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- AREG
- AREGB
- BTC
- DTR
- DTS
- EGF
- EGFR
- EPGN
- ERBB
- ERBB1
- EREG
- HBEGF
- HEGFL
- HER1
- HRAS
- HRAS1
- NRAS
- SDGF
- SHC
- SHC1
- SHCA
- SOS1
- TGFA
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SHC-related events triggered by IGF1R
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- HRAS
- HRAS1
- IBP1
- IGF1
- IGF1R
- IGF2
- NRAS
- SOS1
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SHC-mediated cascade:FGFR4
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- FGF1
- FGF16
- FGF18
- FGF19
- FGF2
- FGF20
- FGF23
- FGF4
- FGF6
- FGF9
- FGFA
- FGFB
- FGFR4
- HRAS
- HRAS1
- HST
- HST2
- HSTF1
- HSTF2
- HYPF
- JTK2
- KLB
- KS3
- NRAS
- SOS1
- TKF
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